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V0405 Dra:A New Deep and Low Mass Ratio Contact Binary with Extremely Fast Decrease in the Orbital Period

Research in Astronomy and Astrophysics 2024年第6期24卷 287-293页

作者： Chao-Yue Li Lin-Qiao Jiang Jie Zheng Yi-man Liu xiao-Yu Long Min Sun Han-Lu Zhang xiao-man Tian School of Science Leshan Normal UniversityLeshan 614000China Center for Applied Optics Research Leshan Normal UniversityLeshan 614000China Key Laboratory of Detection and Application of Space Effect in Southwest Sichuan Leshan 614000China CAS Key Laboratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China School of Aeronautics Shandong Jiaotong UniversityJinan 250000China

V0405 Dra is a W UMa-type binary *** on the TESS data,we have conducted an orbital period study and performed a light curve analysis for the *** orbital period study reveals that the O-C curve for V0405 Dra exhibits secular decrease at an extremely high rate of d P/dt=-2.71×10^(-6)day year^(-1),along with periodic variations characterized by an amplitude of A_(3)=0.0032 day and a period of P_(3)=1.413 *** orbital periodic change is possibly due to the light-travel time effect resulting from an additional third body in the system,for which we estimate a minimum mass of M_(3)=0.77M_(⊙).By employing the 2013 version of the Wilson-Devinney(W-D)method to synthesize a light curve,we derived photometric solutions indicating that V0405 Dra is a new deep(f=68.7%)and low-mass ratio(q=0.175)contact *** fast decrease in its orbital period is likely caused by mass transfer from the more massive primary star to the less massive secondary star,or due to angular momentum *** further mass transfer and loss of angular momentum,the binary will gradually evolve into a tighter contact configuration,eventually leading to a merger into a single star,following the evolutionary paths suggested for such deep and low mass ratio contact binaries.

关键词： (stars:)binaries(including multiple):close (stars:)binaries:eclipsing stars:individual(V0405 Dra)

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Analysis of destructive effect of Zn on carbon brick and way of Zn into carbon brick

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Journal of Iron and Steel Research(International) 2024年第6期31卷 1344-1354页

作者： Peng-bo Liu Shu-sen Cheng Yu-qing Xue xiao-man Cheng Zhao Liu University of Science and Technology Beijing Beijing 100083China Ministry of Ironmaking Shangdong Taishan Steel Group Co.Ltd.Taian 271000ShandongChina

The service life of a blast furnace depends largely on the degree of damage to the carbon brick in the *** brick and ramming material in the hearth of a 1780 m3 blast furnace after shutdown were sampled and *** was found that the substances in the cracks of the carbon brick near and above the taphole were ZnO and Zn_(2)SiO_(4),whereas the substances in the cracks of the carbon brick below the taphole were *** reaction of Zn with CO,SiO_(2),and Fes generates ZnO,Zn_(2)SiO_(4),and ZnS,resulting in volume expansion,which is an important reason for the cracking of carbon ***,several obvious Zn vapor flow channels were found in the ramming material,through which Zn vapor could enter the carbon brick,causing damage to the carbon *** the compactness of the ramming material is beneficial to preventing Zn vapor from entering the carbon brick through the voids in the ramming material,reducing the destructive effect of Zn on the carbon brick and further extending the service life of the blast furnace.

关键词： Zn Blast furnace Carbon brick Ramming material Crack

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Mechanistic study of lipid metabolism disorders in diabetic kidney disease treated with GLQMP based on network pharmacology,molecular docking and in vitro experiments

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Traditional Medicine Research 2024年第2期9卷 42-51页

作者： Shu-man Liu Zi-Jie Yan man xiao Yi-Qiang Xie College of Traditional Chinese Medicine Hainan Medical UniversityHaikou 571199China Key Laboratory of Biochemistry and Molecular Biology Hainan Medical UniversityHaikou 571199China.

Background:In this study,we used network pharmacology and molecular docking combined with vitro experiments to explore the potential mechanism of action of Gualou Qumai pill(GLQMP)against ***:We screened effective compounds and drug targets using Chinese medicine systemic pharmacology database and analysis platform and Chinese medicine molecular mechanism bioinformatics analysis tools;and searched for DKD targets using human online Mendelian genetics and gene *** potential targets of GLQMP for DKD were obtained through the intersection of drug targets and disease *** software was applied to build herbal medicine-active compound-target-disease networks and analyze them;protein-protein interaction networks were analyzed using the STRING database platform;gene ontology and Kyoto Encyclopedia of Genes and Genomes were used for gene ontology and gene and genome encyclopedia to enrich potential targets using the DAVID database;and the AutoDock Vina 1.1.2 software for molecular docking of key targets with corresponding key *** vitro experiments were validated by CCK8,oil red O staining,TC,TG,RT-qPCR,and Western ***:Through network pharmacology analysis,a total of 99 potential therapeutic targets of GLQMP for DKD and the corresponding 38 active compounds were obtained,and 5 core compounds were *** constructing the protein-protein interaction network and performing network topology analysis,we found that PPARA and PPARG were the key targets,and then we molecularly docked these two key targets with the 38 active compounds,especially the 5 core compounds,and found that PPARA and PPARG had good binding ability with a variety of *** vitro experiments showed that GLQMP was able to ameliorate HK-2 cell injury under high glucose stress,improve cell viability,reduce TC and TG levels as well as decrease the accumulation of lipid droplets,and RT-qPCR and Western blot confirmed that GLQMP was able to promote the expressi

关键词： Gualou Qumai pill diabetic kidney disease disorder of lipid metabolism network pharmacology molecular docking

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The structure of TRAF7 coiled-coil trimer provides insight into its function in zebrafish embryonic development

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Journal of Molecular Cell Biology 2024年第1期16卷 43-53页

作者： xiaozhen Song Ruixing Hu Yi Chen man xiao Hong Zhang Shengnan Wu Qing Lu Molecular Diagnostic Laboratory Shanghai Children’s HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200040China Bio-X Institutes Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders(Ministry of Education)Shanghai Jiao Tong UniversityShanghai 200030China Laboratory of Development and Diseases and State Key Laboratory for Medical Genomics Shanghai Institute of HematologyRuĳin HospitalShanghai JiaoTong University School of MedicineShanghai 200025China

TRAF7 serves as a crucial intracellular adaptor and E3 ubiquitin ligase involved in signal transduction pathways,contributing to immune responses,tumor progression,and embryonic *** mutations within the coiled-coil(CC)domain and WD40 repeat domain of TRAF7 could cause brain tumors,while germline pathogenic mutations contribute to severe developmental ***,the precise molecular mechanism underlying TRAF7 involvement in embryonic development remains *** this study,we employed zebrafish as an in vivo model ***7 knock down caused defects in zebrafish embryonic *** determined the crystal structure of TRAF7 CC domain at 3.3Åresolution and found that the CC region trimerization was essential for TRAF7 functionality during zebrafish embryonic ***,disease-causing mutations in TRAF7 CC region could impair the trimer formation,consequently impacting early embryonic development of ***,our study sheds light on the molecular mechanism of TRAF7 CC trimer formation and its pivotal role in embryonic development.

关键词： TRAF7 coiled-coil domain crystal structure trimerization embryonic development

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Laparoscopic spleen-preserving total pancreatectomy for the treatment of low-grade malignant pancreatic tumors:Two case reports and review of literature

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World Journal of Clinical Cases 2024年第17期12卷 3206-3213页

作者： Meng-Qing Sun xiao-man Kang xiao-Dong He Xian-Lin Han Department of General Surgery Peking Union Medical College HospitalChinese Academy of Medical SciencesBeijing 100730China

BACKGROUND Function-preserving pancreatectomy can improve the long-term quality of life of patients with benign or low-grade malignant tumors,such as intraductal papillary mucinous neoplasms(IPMNs)and mucinous cystic ***,there is limited literature on laparoscopic spleen-preserving total pancreatectomy(LSpTP)due to technical *** SUMMARY Patient 1 was a 51-year-old male diagnosed with IPMN based on preoperative imaging,showing solid nodules in the pancreatic head and diffuse dilation of the main pancreatic duct with atrophy of the distal *** performed L-SpTP with preservation of the splenic vessels,and the postoperative pathology report revealed IPMN with invasive *** 2 was a 60-year-old male with multiple cystic lesions in the pancreatic head and body.L-SpTP was performed,and intraoperatively,the splenic vein was injured and required *** pathology revealed a mucinous cystic tumor of the pancreas with low-grade *** patients were discharged on postoperative day 7,and there were no major complications during the perioperative *** We believe that L-SpTP is a safe and feasible treatment for low-grade malignant pancreatic tumors,but more case studies are needed to evaluate its safety,efficacy,and long-term outcomes.

关键词： Complete laparoscopic surgery Spleen-preserving total pancreatectomy Lowgrade malignant pancreatic tumors Function-preserving pancreatectomy Case report

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Exploring the molecular mechanism of Suoquan pill in the treatment of diabetic kidney disease based on network pharmacology,molecular docking,in vitro experiment

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Traditional Medicine Research 2024年第11期9卷 27-37页

作者： Zi-Jie Yan Yu Kang Shu-man Liu Fang-Yu Wang man xiao Yi-Qiang Xie College of Traditional Chinese Medicine Hainan Medical UniversityHaikou 571199China Graduate School Heilongjiang Academy of Traditional Chinese MedicineHarbin 150001China Department of Pharmacology College of PharmacyHainan Medical UniversityHaikou 571199China Key Laboratory of Biochemistry and Molecular Biology Hainan Medical UniversityHaikou 571199China.

Background:Diabetic kidney disease(DKD)is a microvascular complication of diabetes mellitus and is the main cause of end-stage renal *** pills(SQP)has a variety of pharmacological activities and multiple therapeutic effects,and it is used clinically as a basic formula for the treatment of ***:Public databases were used to identify SQP compounds and the potential targets of SQP and DKD.A drug-component-therapeutic target network was ***-protein interaction network analysis,Gene Ontology functional analysis,and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis were used to analyse the potential molecular mechanisms of SQP based on common targets of drugs and *** docking simulations were conducted to confirm the binding abity of the core compounds to key *** efficacy and predicted molecular mechanisms of SQP were validated using cell counting kit-8 assay,flow cytometry,and western blotting with HK-2 cells as a ***:Network pharmacology analysis showed that 26 compounds and 207 potential targets of SQP were involved in the treatment of DKD;boldine,denudatin B,pinocembrin,kaempferoid,and quercetin were considered core compounds,and epidermal growth factor receptor(EGFR)and proto-oncogene,non-receptor tyrosine kinase(SRC)were considered key *** Ontology enrichment analysis indicated that protein phosphorylation and negative regulation of apoptotic processes are important biological processes in the treatment of DKD by *** docking confirmed the excellent binding abilities of boldine,denudatin B,kaempferide,and quercetin to EGFR and *** results of in vitro experiments showed that treatment with an ethanolic extract of SQP significantly protected HK-2 cells from high glucose-induced cell *** addition,the SQP ethanol extract inhibited the phosphorylation of EGFR and SRC,suppressed the apoptosis rate,and regulated apoptosis-related proteins in HK-2 cells under hig

关键词： traditional Chinese medicine diabetic kidney disease Suoquan pill network analysis molecular docking

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ZnS@CdS/HAP复合微球的SILAR法制备及光催化性能

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中国环境科学 2024年第2期44卷 851-858页

作者：杨莉靳晓曼姜晓雪王柯罗玥长安大学水利与环境学院陕西西安710064 长安大学旱区地下水文与生态效应教育部重点实验室陕西西安710064 长安大学水利部旱区生态水文与水安全重点实验室陕西西安710064 中国电建集团西北勘测设计研究院有限公司陕西西安710065

以酵母模板法制备的中空羟基磷灰石(HAP)微球为基底,通过连续离子层吸附反应法(SILAR)制备ZnS@CdS/HAP复合微球,利用XRD、SEM、UV-vis等表征手段分析材料的晶体结构、微观形貌和光吸收能力等,同时结合亚甲基蓝的光催化降解实验探讨复合... 详细信息

以酵母模板法制备的中空羟基磷灰石(HAP)微球为基底,通过连续离子层吸附反应法(SILAR)制备ZnS@CdS/HAP复合微球,利用XRD、SEM、UV-vis等表征手段分析材料的晶体结构、微观形貌和光吸收能力等,同时结合亚甲基蓝的光催化降解实验探讨复合微球的光催化机理.结果表明:利用SILAR法成功实现了ZnS@CdS/HAP复合微球的制备,ZnS@CdS/HAP复合微球的直径约为3~5μm且分散性良好,在可见光区有良好的吸收性能,具有优异的光催化活性,在催化剂添加量1g/L、pH=7、温度为25℃的条件下,对50mL浓度为10mg/L的亚甲基蓝溶液可见光催化100min时去除率高达93%.机理分析证实,ZnS@CdS/HAP光催化可能存在的Z型电荷迁移机制在有效抑制光生载流子复合的同时有效抑制光生腐蚀的发生,提升了ZnS@CdS/HAP复合微球的光催化活性和稳定性.

关键词： CdS ZnS 光腐蚀 HAP 光催化稳定性

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基于Sentinel-2和3D多源域自注意力模型的湿地分类

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遥感学报 2024年第1期28卷 266-279页

作者：楼桉君贺智肖曼李心媛中山大学地理科学与规划学院广州510275 南方海洋科学与工程广东省实验室(珠海) 珠海519082

准确的湿地分类可掌握湿地时空分异特征,在湿地研究中占据重要地位。针对现有基于小样本学习的湿地分类方法仅局限于利用目标域或单源域数据的问题,本文提出一种3D多源域自注意力小样本学习模型3DMDAFSL(3D Multi-source Domain self-At... 详细信息

准确的湿地分类可掌握湿地时空分异特征,在湿地研究中占据重要地位。针对现有基于小样本学习的湿地分类方法仅局限于利用目标域或单源域数据的问题,本文提出一种3D多源域自注意力小样本学习模型3DMDAFSL(3D Multi-source Domain self-Attention Few-Shot Learning)。首先,结合卷积和注意力机制的优势,设计基于自注意力机制和深度残差卷积的3D特征提取器;然后,采用对抗域自适应策略实现多源域特征对齐,在每个域分别进行小样本学习;最后,利用训练好的模型提取特征,并将特征输入至K近邻(K-nearest Neighbor)分类器以获取分类结果。结果表明,3D特征提取器相比无特征提取框架的湿地总体分类精度提升约6.79%;当使用多源域数据集时,3D-MDAFSL模型对中山市Sentinel-2湿地数据集的总体分类精度能达到93.52%,相比于现有算法有明显提升。本文所提出的3D-MDAFSL模型在湿地地物高精度提取和分类中有较好的应用价值。

关键词：遥感小样本湿地分类多源域自注意力

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层级治理体系下的政策再生产、注意力配置与政策效应——基于双重机器学习模型的数字乡村政策执行研究

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华中科技大学学报（社会科学版） 2024年第3期38卷 117-128页

作者：薛增鑫满小欧东北大学文法学院

政策再生产作为政策制定与政策执行的中间环节,是我国层级治理体系下实现顶层设计统一性与地方情境特殊性整合的关键机制。为回应当前对政策再生产政策效应及其内在机制探究不足的局限,本研究结合新制度理论和注意力基础观理论,构建了... 详细信息

政策再生产作为政策制定与政策执行的中间环节,是我国层级治理体系下实现顶层设计统一性与地方情境特殊性整合的关键机制。为回应当前对政策再生产政策效应及其内在机制探究不足的局限,本研究结合新制度理论和注意力基础观理论,构建了“政策再生产—注意力配置—政策效应”的整合分析框架,并基于数字乡村政策执行情境,引入双重机器学习模型(DML),实证检验了省级政府数字乡村政策再生产的政策效应以及地市级政府注意力配置的中介效应。研究发现,政策再生产与数字乡村建设水平之间呈现倒U形关系,且省级政府政策再生产的正向影响大于负向影响,呈现“非对称”性。进一步因果中介效应检验发现,地市级政府注意力配置在政策再生产对数字乡村建设水平的影响中发挥正向中介作用。因而,应从政策属性、组织权责和府际利益等层面合理调控政策再生产的边界与限度,注重提升政策设计与政府注意力的适配度,从而实现层级落实过程中政策绩效的稳定提升。

关键词：政策再生产注意力配置政策效应数字乡村机器学习

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罗进德:译道“四栖”翻译家

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上海翻译 2024年第1期 68-73,F0003页

作者：黄忠廉王小曼延边大学吉林延吉136200 深圳大学广东深圳518060

罗进德精通汉、英、俄三语,一生从译、从教,为译界办刊,出版译学图书,推进国家翻译实践,对翻译既至诚与至真,观察、思考与研究翻译也能至理,推动国内外译事发展更能至善;“四至”之中,既含他丰富的翻译人生,也显其所达的高度,是译(学)... 详细信息

罗进德精通汉、英、俄三语,一生从译、从教,为译界办刊,出版译学图书,推进国家翻译实践,对翻译既至诚与至真,观察、思考与研究翻译也能至理,推动国内外译事发展更能至善;“四至”之中,既含他丰富的翻译人生,也显其所达的高度,是译(学)界难得的“四栖”翻译家。

关键词：罗进德 “四栖”翻译家译道

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