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Enhancing mechanism of intestinal absorption of highly lipophilic compounds using microemulsion e Quantitative analysis of the partitioning to the mesenteric lymph in intestinal cells

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Asian Journal of Pharmaceutical Sciences 2015年第3期10卷 186-193页

作者： Kazunori Iwanaga Yoichi Higashiyama makoto Miyazaki Masawo Kakemi Division of Pharmaceutics Osaka University of Pharmaceutical Sciences4-20-1 NasaharaTakatsukiOsaka 569-1094Japan

The purpose of this study was to quantify the effect of the fatty acid alkyl-chain length of a polyethylene glycol(PEG)glyceryl ester,which was used as a microemulsion oil component,on the partitioning of highly lipophilic compounds to the mesenteric lymph after oral *** blue N,a highly lipophilic anthraquinone derivative,was orally administered to lymph duct-cannulated and untreated rats in two kinds of different ***®50/13 and Gelucire®44/14 were used as the oil component with long chain and medium chain fatty acid portions,respectively,of PEG glyceryl esters in *** cumulative amount of oil blue N in lymph fluid was almost the same between the two microemulsions,although the transferred amount of oil component(triglyceride)in the lymph after administration of the Gelucire®50/13 microemulsion was significantly higher than that of the Gelucire®44/14 *** the other hand,the solubility of oil blue N in Gelucire®44/14 was much higher than that in Gelucire®50/*** significant differences were observed between microemulsions in the bioavailability of oil blue *** these data,the partitioning of oil blue N to the lymph was calculated using a mathematical model,showing that the partitioning ratios of oil blue N to the lymph fluid were almost the same for both *** solubility of oil blue N to the oil component of the microemulsions and the transfer of triglycerides to the lymph after administration of the microemulsions counteract each other,leading to similar partitioning ratios of oil blue N to the lymph.

关键词： Microemulsion Intestinal absorption Mesenteric lymph Partition Quantitative analysis

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Acquisition of hyponymy relations for agricultural terms from a Japanese statutory corpus

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Information Processing in Agriculture 2014年第2期1卷 95-104页

作者： makoto Nakamura Tomohiro Ohno Yasuhiro Ogawa Katsuhiko Toyama Japan Legal Information Institute Graduate School of LawNagoya UniversityFuro-choChikusa-kuNagoya 464-8601Japan Information Technology Center Nagoya UniversityFuro-choChikusa-kuNagoya 464-8601Japan Graduate School of Information Science Nagoya UniversityFuro-choChikusa-kuNagoya 464-8601Japan

This paper,which aims to increment the vocabulary of an existing thesaurus using hyponymy relations,focuses on an agricultural thesaurus called *** main goal is to acquire AGROVOC-qualified candidates from the hyponymy relations of legal texts and *** propose a pattern-based approach to hyponymy relation *** experimental result showed that 222 and 868 candidates are extracted from statutory sentences with 67.1%precision and tables with 37.0%precision,respectively.

关键词： AGROVOC Japanese statutory corpus Legal text processing

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Xanthogranulomatous Inflammation of Myometrium Causing Pelvic Extension: Report of Two Cases

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Open Journal of Obstetrics and Gynecology 2022年第2期12卷 147-153页

作者： Kyousuke Takeuchi Ai Yoshida makoto Sugimoto Masayuki Fujita Hiroki Morita Department of Obstetrics and Gynecology National Hospital Organization Kobe Medical Center Kobe Japan Department of Pathology National Hospital Organization Kobe Medical Center Kobe Japan Department of Obstetrics and Gynecology Kohnan Medical Center Kobe Japan

Background: Xanthogranulomatous inflammation of the female reproductive organs is a rare chronic inflammation. In most reported cases, the lesion was limited to the endometrium and fallopian tubes. Here, we report two cases of xanthogranulomatous inflammation of the myometrium with a history of endometrial biopsy. Case Reports: In two cases, myometrial xanthogranulomatous inflammation destroyed the myometrium. This inflammation developed into surrounding pelvic organs, resulting in uterine perforation. Conclusion: When inflammatory lesions are found after intrauterine manipulation, the possibility of developing xanthogranulomatous inflammation should be considered. If antibiotics are ineffective, prompt surgical treatment is necessary.

关键词： Xanthogranulomatous Inflammation Myometrium Klebsiella Pneumoniae Surgical Intervention Endometrial Biopsy

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Formation mechanism of extension fractures induced by excavation of a gallery in soft sedimentary rock,Horonobe area,Northern Japan

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Geoscience Frontiers 2013年第1期4卷 105-111页

作者： Tetsuya Tokiwa Kimikazu Tsusaka makoto Matsubara Taiki Ishikawa Daisuke Ogawa Horonobe Underground Research Unit Japan Atomic Energy AgencyHokkaido 098-3224Japan Geoscience Research Laboratory Kanagawa 242-0014Japan Mitsubishi Materials Techno Corporation Tokyo 102-8205Japan

This paper focuses on the formation mechanism of fractures induced by excavation of a gallery in soft sedimentary rocks in the Horonobe area of Japan. Detailed fracture mapping of the gallery indicates that the fractures consist of both pre-existing shear fractures and excavation damaged zone （EDZ） fractures. EDZ fractures correspond to weak planes associated with bedding planes or transgranular cracks. The EDZ fractures terminate against pre-existing shear fractures. Therefore, even for excavations in soft sedimentary rocks, formation of the EDZ fractures are controlled by pre-existing fractures and earlier weak planes.

关键词： Fracture Excavation damaged zone (EDZ)Weak plane Soft rock Excavation

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Starch metabolism and grain chalkiness under high temperature stress

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National Science Review 2016年第3期3卷 280-282页

作者： Pei-Ching Lo Li Hu Hidemi Kitano makoto Matsuoka Graduate School of Bioagricultural Sciences Nagoya University Bioscience and Biotechnology Center Nagoya University

Rice is one of the most important staple crops,demand for which is increasing with population growth all over the world,especially in *** of recent global warming,significant reduction in yield and quality of rice has now become a serious *** of the most common damages incurred by high temperature(HT) stress is grain *** grains show loosely packed

关键词： QTLs GBSSI Starch metabolism and grain chalkiness under high temperature stress high

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Effects of zincate treatment on adhesion of electroless Ni-P coating onto various aluminum alloys

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中国有色金属学会会刊：英文版 2009年第4期19卷 814-818页

作者： makoto HINO Koji MURAKAMI Yutaka MITO OKA Ken MURAOKA Teruto KANADANI Industrial Technology Research Institute of Okayama Prefecture Okayama University of Science

The effects of alloying elements on zincate treatment and adhesion of electroless Ni-P coating onto various aluminum alloy substrates were *** morphology of zinc deposits in the 1st zincate treatment and its adhesion were changed depending on the alloying *** zinc deposits in the 2nd zincate treatment became thinly uniform,and the adhesion between aluminum alloy substrate and Ni-P coating was improved irrespective of the alloying *** analysis revealed the existence of zinc on the surface of each aluminum alloy substrate after the pickling in 5% nitric *** zinc on the surface should be an important factor influencing the morphology of zinc deposit at the 2nd zincate treatment and its adhesion.

关键词：化学镀镍锌酸盐铝合金治疗合金涂层粘连合金元素表面形貌

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Turbo-pump with Isolated Two Stage Impellers for Future Rocket Engine (Trial to Drive Impellers Independently)

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Journal of Thermal Science 2008年第1期17卷 28-34页

作者： Toshiaki Kanemoto makoto Shimojyo Ryunosuke Kawashima Daisuke Tanaka Akira Inagaki Shin Oba Kyushu Institute of Technology:Sensui 1-1 TobataKitakyushu 804-8550Japan Professor Kyushu Institute of Technology:Sensui 1-1 TobataKitakyushu 804-8550Japan DMW Corporation:Miyoshi 3-27 Mishima 411-8560Japan

为了在 impellers 压制成穴并且做涡轮泵，更长生活， inducer 与主要 impeller 被分开，两 impellers 独立地被驾驶。在 impellers 附近的泵和流动条件的表演试验性地被调查，下列结果被获得。(1 ) 主要 impeller 贡献在 inducer 和主... 详细信息

为了在 impellers 压制成穴并且做涡轮泵，更长生活， inducer 与主要 impeller 被分开，两 impellers 独立地被驾驶。在 impellers 附近的泵和流动条件的表演试验性地被调查，下列结果被获得。(1 ) 主要 impeller 贡献在 inducer 和主要 impeller 之间的流动相互作用。(2 ) 两 impellers 的旋转速度能独立地被控制以便同时总体上压制成穴不仅 impeller，而且在 inducer。

关键词：离心式水泵诱导物涡轮机火箭发动机 NPSH

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Experimental Study of Heating Fluid between Two Concentric Cylinders with Cavities

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Journal of Thermal Science 2008年第2期17卷 175-180页

作者： Hiromitsu HAMAKAWA Hiroyuki MORI makoto IINO Masaaki HORI Mizuho YAMASAKI Toshiaki SETOGUCHI Department of Mechanical Engineering Oita University EBARA Kyushu Co. Ltd. Fanuc LTD Kawasaki Heavy Industries Ltd. Department of Mechanical Engineering Saga University

在这篇论文，我们在在有洞的内部柱体被旋转的二同心柱体之间的环隙涉及加热液体，外部柱体在休息。加热液体和成穴行为上的内部柱体的洞的效果被检验。我们测量了流动率，转子的旋转速度，磨擦转矩，温度上升和压力在这台设备的入口和... 详细信息

在这篇论文，我们在在有洞的内部柱体被旋转的二同心柱体之间的环隙涉及加热液体，外部柱体在休息。加热液体和成穴行为上的内部柱体的洞的效果被检验。我们测量了流动率，转子的旋转速度，磨擦转矩，温度上升和压力在这台设备的入口和插头之间落下。水的流动率从 0.42 × 1 0 −4 到 4.59 × 1 在入口的 0 −4 m 3/s。磨擦转矩和有洞的内部柱体的热的数量比没有洞的盒子大，并且当内部柱体的旋转速度增加了，他们增加了。当内部柱体的旋转速度增加了，效率接近了大约 1。在内部柱体的表面上的洞的成穴的行为被讨论。

关键词：剪切流同心环状物摩擦性能热处理

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Discussion on the mechanism of ground improvement method at the excavation of shallow overburden tunnel in difficult ground

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Underground Space 2016年第2期1卷 94-107页

作者： Kiyoshi Kishida Ying Cui Masaichi Nonomura Tomomi Iura makoto Kimura Department of Urban Management Kyoto UniversityKyoto 615-8540Japan Department of Civil Engineering Meijo UniversityNagoya 468-5802Japan Railway Engineering Co.Ltd. Tokyo 105-0012Japan Japan Railway Construction Transport and Technology AgencyYokohama 231-8351Japan Department of Civil and Earth Resources Engineering Kyoto UniversityKyoto 615-8540Japan

Tunnel construction opportunities involving shallow overburdens under difficult(e.g.,soft,unconsolidated)grounds have been increasing in *** auxiliary methods for excavating mountain tunnels have been developed and can satisfy stringent construction *** ground improvement method,which is one of the auxiliary methods for shallow overburden tunnels,has demonstrated its ability to effectively control the amount of settlement under soft ***,the mechanism of the ground improvement method has not been clarified,nor has a suitable design code been established for ***,because the strength of the improved ground and the suitable length and width of the improved area have not been fully understood,an empirical design has been applied in every *** this paper,the mechanical behavior during the excavation,including that of the stabilized ground,is evaluated through trapdoor experiments and numerical *** addition,the enhancement of tunnel stability resulting from the application of the ground improvement method is discussed.

关键词： Auxiliary method Shallow overburden Soft ground Ground improvement Settlement

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On Minimal Surfaces in Space Forms Whose Gauss Imageshave Constant Curvature

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Chinese Quarterly Journal of Mathematics 1995年第4期10卷 74-77页

作者： makoto SAKAKI Dpartment of

ＯｎＭｉｎｉｍａｌＳｕｒｆａｃｅｓｉｎＳｐａｃｅＦｏｒｍｓＷｈｏｓｅＧａｕｓｓＩｍａｇｅｓｈａｖｅＣｏｎｓｔａｎｔＣｕｒｖａｔｕｒｅ￥ＭａｋｏｔｏＳＡＫＡＫＩ（ＤｐａｒｔｍｅｎｔｏｆＭａｔｈｅｍａｔｉｃｓ，Ｆａｃｕｌ... 详细信息

ＯｎＭｉｎｉｍａｌＳｕｒｆａｃｅｓｉｎＳｐａｃｅＦｏｒｍｓＷｈｏｓｅＧａｕｓｓＩｍａｇｅｓｈａｖｅＣｏｎｓｔａｎｔＣｕｒｖａｔｕｒｅ￥ＭａｋｏｔｏＳＡＫＡＫＩ（ＤｐａｒｔｍｅｎｔｏｆＭａｔｈｅｍａｔｉｃｓ，ＦａｃｕｌｔｙｏｆＳｃｉｅｎｃｅ，Ｈｉｒｏｓ...

关键词：常曲率极小曲面高斯象点空间形式

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