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Paraben Content in Adjacent Normal-malignant Breast Tissues from Women with Breast Cancer

Biomedical and Environmental Sciences 2019年第12期32卷 893-904页

作者： Mohammad Mehdi Amin Maryam Tabatabaeian Afsane Chavoshani Elham Amjadi majid Hashemi Karim Ebrahimpour Roya Klishadi Sedigheh khazaei Maijan Mansourian Environment Research Center Research Institute for Primordial Prevention of Non-Communicable DiseaseIsfahan University of Medical SciencesIsfahanIran Department of Environmental Health Engineering School of HealthIsfahan University of Medical SciencesIsfahanIran Breast Surgeon Board certificate in general surgery in Anahid ClinicIsfahanIran Student Research Committee Isfahan University of Medical SciencesIsfahanIran Anatomical Clinical Pathologist Poursina Hakim Digestive Diseases Research CenterIsfahan University of Medical SciencesIsfahanIran Environmental Health Engineering School of Public HealthKerman University of Medical SciencesKermanIran Environmental Health Engineering Research Center Kerman University of Medical SciencesKermanIran Child Growth and Development Research Cen ter Research Institute for Primordial Prevention of Non-Communicable DiseaseIsfahan University of Medical SciencesIsfahanIran Microbiologist Molecular Pathology Research CenterImam Reza HospitalKermanshah University of Medical SciencesKermanshahIran Department of Biostatistics and Epidemiology School of HealthIsfahan University of Medical SciencesIsfahanIran

Objective Accumulation of estrogenic compounds and other carcinogens in normal breast tissues contributes to unpredictable breast cancer incidence during adolescence and throughout *** assess the role of parabens in this phenomenon,the paraben content of adjacent normal-malignant breast tissues is measured in women with breast cancer living in Isfahan Province,*** Adjacent normal-malignant breast tissue samples were obtained from 53 *** parabens including methyl-paraben(Me PB),ethyl-paraben(Et PB),propyl-paraben(Pr PB),and butylparaben(Bu PB)were extracted from the sample supernatant and then subjected to gas chromatography *** Some risk factors for breast cancer were stimulated by parabens in adjacent malignant-normal breast tissues among young and middle-aged women with breast *** observed a significant association for dose-response pattern of Me PB[OR=98.34(11.43–185.2),P=0.027]for both ER+and PR+women and Me PB[OR=164.3(CI:112.3–216.3),P<0.001]for HER2+women than women with negative *** risk of 95-fold increase in Me PB dose and 164-fold increase in∑PBs dose were significant for women with hereditary breast cancer in first-degree *** These results may promote future epidemiology studies and strategies to improve women's lifestyle and consume paraben-free products.

关键词： Paraben Breast cancer Malignant tissues Normal tissues Demography Risk factors

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Forty Years of Air Temperature Change over Iran Reveals Linear and Nonlinear Warming

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Journal of Meteorological Research 2022年第3期36卷 462-477页

作者： majid KAZEMZADEH Zahra NOORI Sadegh JAMALI Abdulhakim M.ABDI Faculty of Natural Resources University of Tehran77871-31587KarajIran Department of Technology and Society Lund UniversitySE-22100LundSweden Centre for Environmental and Climate Science Lund UniversitySE-22362LundSweden

Spatiotemporal analysis of long-term changes in air temperature is of prime importance for climate change research and the development of effective mitigation and adaptation *** there are considerable studies on air temperature change across the globe,most of them have been on linear trends and time series analysis of nonlinear trends have not received enough ***,spatiotemporal patterns of monthly and annual mean(Tmean),maximum(T_(max)),and minimum(T_(min))air temperature at 47 synoptic stations across climate zones in Iran for a 40-yr period(1978–2017)are analyzed.A polynomial fitting scheme(Polytrend)is used to both monthly and annual air temperature data to detect trends and classify them into linear and nonlinear(quadratic and cubic)*** significant(non-significant)trends in Tmean,T_(max),and T_(min) across all climate zones are 41.1%(58.9%),34.1%(65.9%),and 46%(54%),*** highest magnitude of increasing trends is observed in the annual T_(min)(0.47℃decade−1)and the lowest magnitude is for the annual T_(max)(0.4℃decade−1).Across the country,increasing trends(=37.2%)have higher spatial coverage than the decreasing trends(=3.2%).Warming trends in Tmean(65.3%)and T_(min)(73.1%)are mainly observed in humid climate zone while warming trends in T_(max) are in semi-arid(43.9%)and arid(34.1%)*** change with a positive trend is predominant in all Tmean(56.7%),T_(max)(67.8%),and T_(min)(71.2%)and for both monthly and annual ***,the linear trends have the highest warming rate in annual T_(min)(0.83℃decade^(−1))and Tmean(0.46℃decade^(−1))whereas the nonlinear trends have the highest warming rate in annual T_(max)(0.52℃decade^(−1)).The linear trend type is predominant across the country especially in humid climate zones whereas the nonlinear trends(quadratic and cubic)are mainly observed in the arid climate *** study highlights nonlinear changes and spatiotemporal trends in air temperature in Iran an

关键词： linear trends nonlinear trends time series analysis air temperature Polytrend Iran

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Enzymatic activity and physico-chemical changes of terminal bud in rain-fed fig(Ficus carica L. ‘Sabz’) during dormant season

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Horticultural Plant Journal 2022年第2期8卷 195-204页

作者： Sahar Sedaghat Badii Gaaliche majid Rahemi Hamid Zare Moslem Jafari Department of Horticultural Science Faculty of AgricultureShiraz UniversityShiraz***Iran Laboratory of Horticulture National Agricultural Research Institute of Tunisia(INRAT)IRESA-University of CarthageEl MenzahTunis 1004Tunisia Fig Research Station Fars Agricultural and Natural Resources Research and Education CenterAgricultural ResearchEducation and Extension Organization(AREEO)Estahban 74518778Iran

Rain-fed fig culture is known to provide a good quality of dried figs, while almost no research has been reported so far on the enzyme activity comparisons of seasonal variations among terminal buds in this plant. Toward this goal, we evaluated the physiochemical changes of terminal buds of fig 'Sabz' and their micromorphology during the dormant season(November to April) using Scanning Electron Microscope(SEM) analysis during two consecutive years(2016 and 2017). Results indicated that the highest contents of total sugars in terminal fig buds were registered in January and the lowest values were noticed in April. SEM analysis showed the presence of vegetative terminal fig buds during the dormant season and after bud-break in April. An increasing trend was observed for the protein content, length and diameter of terminal buds at the beginning of bud-break. In dormant buds, ascorbate peroxidase, peroxidase and catalase enzymes exhibited initially an ascending pattern,while it decreased from December. A second increase for these enzymes occurred during the dormant season until bud-break. Superoxide dismutase activity increased in buds during the dormancy season until bud-break. Proline content remained stable in buds from November to February, while it decreased rapidly until bud-break. Furthermore, a downward trend of the total phenol content in buds was observed between the onset and end of dormant period. In general, the dormant buds in 'Sabz' fig cultivar were metabolically active with a short dormant period under the rain-fed conditions.

关键词： Fig Dormancy Bud break Enzyme activity Micromorphology

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Effect of 2-mercaptobenzothiazole concentration on sour-corrosion behavior of API X60 pipeline steel:Electrochemical parameters and adsorption mechanism

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International Journal of Minerals,Metallurgy and Materials 2022年第2期29卷 271-282页

作者： Masoud Sabzi Amir Hayati Jozani Farzad Zeidvandi majid Sadeghi Saeid Mersagh Dezfuli Young Researchers and Elite Club Dezful BranchIslamic Azad UniversityDezfulIran Department of Materials Science and Engineering Science and Research BranchIslamic Azad UniversityTehranIran Center of Excellence for Surface Engineering and Corrosion Protection of Industrial School of Metallurgy and Materials EngineeringCollege of EngineeringUniversity of TehranP.O.Box 11155-4563TehranIran

We investigated the effect of the 2-mercaptobenzothiazole concentration on the sour-corrosion behavior of API X60 pipeline steel in an environment containing H_(2)S at 25°C and in the presence of 0,2.5,5.0,7.5,and 10.0 g/L of 2-mercaptobenzothiazole *** examine this behavior,we conducted open-circuit potential(OCP),potentiodynamic polarization,and electrochemical impedance spectroscopy(EIS)*** dispersive spectroscopy and scanning electron microscopy were also used to analyze the corrosion *** results of the OCP and potentiodynamic polarization tests revealed that 2-mercaptobenzothiazole reduces the speed of both the anodic and cathodic *** assessment of the Gibbs free energy of the inhibitor(△G_(ads)^(■))indicated that its value was less than-20 kJ·mol^(-1)and greater than-40 k J·mol^(-1).Therefore,the adsorption of 2-mercaptobenzothiazole onto the surface of the API X60 pipeline steel occurs both physically and chemically,the latter of which is particularly *** addition,as the△G_(ads)^(■)dsvalue was negative,we could conclude that the adsorption of 2-mercaptobenzothiazole onto the surface of the pipeline steel occurs *** EIS results indicate that with the increase in the 2-mercaptobenzothiazole inhibitor concentration,the corrosion resistance of API X60 steel *** analysis of the corrosion products revealed that iron sulfide compounds form on the *** summary,the results showed that an increase in the inhibitor concentration results in a decrease in the corrosion rate and an increase in inhibitory ***,we found that the 2-mercaptobenzothiazole adsorption process on the API X60 steel surfaces in an H2 S-containing environment follows the Langmuir adsorption isotherm and occurs spontaneously.

关键词： API X60 steel sour corrosion 2-mercaptobenzothiazole inhibitor concentration electrochemical parameters environments containing hydrogen sulfide

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Blockchain-based DDoS attack mitigation protocol for device-to-device interaction in smart home

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Digital Communications and Networks 2023年第2期9卷 383-392页

作者： Bello Musa Yakubu majid Iqbal Khan Abid Khan Farhana Jabeen Gwanggil Jeon Department of Mathematics and Computer Science Chulalongkorn UniversityBangkok10330Thailand Department of Computer Science COMSATS University Islamabad(CUI)Islamabad45550Pakistan College of Science and Engineering University of DerbyDerbyDE221GBUnited Kingdom Department of Embedded Systems Engineering Incheon National UniversityIncheon22012South Korea

Smart home devices are vulnerable to a variety of *** matter gets more complicated when a number of devices collaborate to launch a colluding attack(e.g.,Distributed-Denial-of-Service(DDoS))in a network(e.g.,Smart home).To handle these attacks,most studies have hitherto proposed authentication protocols that cannot necessarily be implemented in devices,especially during Device-to-Device(D2D)*** into the potential of Ethereum blockchain and smart contracts,this work proposes a lightweight authentication mechanism that enables safe D2D interactions in a smart *** Ethereum blockchain enables the implementation of a decentralized prototype as well as a peer-to-peer distributed ledger *** work also uses a single server queuing system model and the authentication mechanism to curtail DDoS attacks by controlling the number of service requests in the *** simulation was conducted twenty times,each with varying number of devices chosen at random(ranging from 1 to 30).Each requester device sends an arbitrary request with a unique resource requirement at a *** is done to measure the system's consistency across a variety of device *** experimental results show that the proposed protocol not only prevents colluding attacks,but also outperforms the benchmark protocols in terms of computational cost,message processing,and response times.

关键词： DDoS attack Device-to-device Smart homes Blockchain Authentication Ethereum smartcontract

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Laser-assisted growth of hierarchically architectured 2D MoS2 crystals on metal substrate for potential energy applications

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International Journal of Extreme Manufacturing 2022年第4期4卷 235-244页

作者： Parvin Fathi-Hafshejani Jafar Orangi majid Beidaghi Masoud Mahjouri-Samani Department of Electrical and Computer Engineering Auburn UniversityAuburnAL 36849United States of America Department of Mechanical and Material Engineering Auburn UniversityAuburnAL 36849United States of America

Recently, there has been substantial interest in the large-scale synthesis of hierarchically architectured transition metal dichalcogenides and designing electrodes for energy conversion and storage applications such as electrocatalysis, rechargeable batteries, and supercapacitors. Here we report a novel hybrid laser-assisted micro/nanopatterning and sulfurization method for rapid manufacturing of hierarchically architectured molybdenum disulfide (MoS2) layers directly on molybdenum sheets. This laser surface structuring not only provides the ability to design specific micro/nanostructured patterns but also significantly enhances the crystal growth kinetics. Micro and nanoscale characterization methods are employed to study the morphological, structural, and atomistic characteristics of the formed crystals at various laser processing and crystal growth conditions. To compare the performance characteristics of the laser-structured and unstructured samples, Li-ion battery cells are fabricated and their energy storage capacity is measured. The hierarchically architectured MoS2 crystals show higher performance with specific capacities of about 10 mAh cm-2, at a current rate of 0.1 mA cm-2. This rapid laser patterning and growth of 2D materials directly on conductive sheets may enable the future large-scale and roll-to-roll manufacturing of energy and sensing devices.

关键词： 2D materials laser manufacturing laser patterning energy applications Li-ion battery

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Global trends of cancer:The role of diet,lifestyle,and environmental factors

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Cancer Innovation 2023年第4期2卷 290-301页

作者： Hassan Bahrami majid Tafrihi Independent Health/Nutrition Researcher TehranIran Molecular and Cell Biology Research Laboratory 2 Department of Molecular and Cell BiologyFaculty of SciencesUniversity of MazandaranBabolsarIran

Effective treatment of cancer requires understanding the nature of the disease and accurately addressing the main root *** risk factors for cancer include poor nutrition,an acidogenic diet,an unhealthy lifestyle,and exposure to carcinogens such as toxins,chemicals,and *** risk of developing cancers may be reduced by sufficient oxygenation and maintaining optimal alkalinity and nutritional balance at the cell *** review paper summarizes some diet and lifestyle modifications that may potentially be considered for preventing and controlling some ***,worldwide statistical data for cancer incidence rates published by International Agency for Research on Cancer are analyzed for certain cancers regionally,concerning the effect of dietary habits and environmental factors that meaningfully correlate with the global trends of *** study of cancer root causes integrated with analyzing the statistics related to cancer incidence rates suggests that the risk of developing cancer may be reduced by modifying dietary habits and lifestyle factors,as well as reducing exposure to *** with healthy balanced dietary habits may have a lower cancer risk than those who frequently have unhealthy diets;hence,considering a balanced natural diet and healthy lifestyle may be suggested as a complementary or alternative solution in cancer treatments.

关键词： cancer cancerprevention cancerstatistics environmentalfactors healthydiet lifestyle

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Generalization of Advanced Encryption Standard Based on Field of Any Characteristic

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Computers, Materials & Continua 2022年第12期73卷 6121-6138页

作者： Nabilah Abughazalah majid Khan Noor Munir Ammar SAlanazi Iqtadar Hussain Department of Mathematical Sciences College of SciencePrincess Nourah Bint Abdulrahman UniversityP.O.Box 84428Riyadh 11671Saudi Arabia Department of Applied Mathematics&Statistics Institute of Space TechnologyIslamabadPakistan King Abdulaziz City for Science and Technology RiyadhSaudi Arabia Mathematics Program Department of MathematicsStatistics and PhysicsCollege of Arts and SciencesQatar University2713DohaQatar Statistical Consulting Unit College of Arts and ScienceQatar UniversityDohaQatar

Nowadays most communications are done by utilizing digital transmission *** security of this digital information transmitted through different communication systems is quite *** secrecy of digital data is one of the burning topics of the digitally developed *** exist many traditional algorithms in the literature to provide methods for robust *** most important and recent modern block cipher named the advanced encryption standard(AES)is one of the extensively utilized encryption schemes with binary *** is a succession of four fundamental steps:round key,sub-byte,shift row,and mix *** this work,we will provide an innovative methodology for extending the AES in a Galois fieldwith any characteristic *** four steps in the fundamental process with binary characteristics will be adjusted because of the new *** applying double affine transformations,we have enhanced the number of options in our suggested substitution *** reconstruction of the nonlinear confusion component and encryption structure provides robustness in the generalized *** increase in the keyspace due to the Galois field generalization implies that we have improved additional confusion abilities and broadened the current *** implementation of the proposed structure of AES for image,audio,and video encryption will provide high security for secure communication.

关键词： AES generalized AES binary field ternary function

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Identification of Composite-Metal Bolted Structures with Nonlinear Contact Effect

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Computers, Materials & Continua 2022年第2期70卷 3383-3397页

作者： Mohammad Ghalandari Ibrahim Mahariq majid Pourghasem Hasan Mulki Fahd Jarad Department of Aerospace Engineering Sharif University of TechnologyTehranIran College of Engineering and Technology American University of theMiddle EastKuwait Faculty of Mechanical and Mechatronics Engineering IHUTehranIran Department of Mathematics Cankaya UniversityEtimesgutAnkaraTurkey Department of Medical Research China Medical University HospitalChina Medical UniversityTaichungTaiwan

The middle layer model has been used in recent years to better describe the connection behavior in composite *** influencing parameters including low pre-screw and high preload have the main effects on nonlinear behavior of the connection as well as the amplitude of the excitation force applied to the ***,in this study,the effects of connection behavior on the general structure in two sections of increasing damping and reducing the stiffness of the structures that lead to non-linear phenomena have been *** to the fact that in composite structure we are faced to the limitation of increasing screw preload which tend to structural damage,so the investigation on the hybrid connection(metal-composite)behavior is *** this research,using the two-dimensional middle layer theory,the stiffness properties of the connection are modeled by normal stiffness and the connection damping is modeled using the structural damping in the shear *** frequency response diagrams have been extracted twice for two different excitation forces and then proposed by a high-order multitasking approximation according to the response range of the nonlinear finite element model for stiffness and damping of the *** effect of increasing the amplitude of the excitation force and decreasing the preload of the screw on the nonlinear behavior of the component has been *** results show that the limited presented novel component model has been accurately verified on the model obtained from the vibration experimental test and the reduction of nonlinear model updating based on that is *** comparison results show good agreementwith a maximumof 1.33%error.

关键词： Nonlinear equation hybrid joint behavior thin laminated element nonlinear frequency response function

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GIScience research challenges for realizing discrete global grid systems as a Digital Earth

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Big Earth Data 2022年第3期6卷 358-379页

作者： majid Hojati Colin Robertson Steven Roberts Chiranjib Chaudhuri Department of Geography and Environmental Studies Wilfrid Laurier UniversityWaterlooONCanada Coldwater Laboratory University of SaskatchewanCanmoreABCanada

Increasing data resources are available for documenting and detecting changes in environmental,ecological,and socioeconomic ***,data are distributed across a wide variety of sources(*** silos)and published in a variety of formats,scales,and semantic representations.A key issue,therefore,in building systems that can realize a vision of earth system monitoring remains data *** global grid systems(DGGSs)have emerged as a key technology that can provide a common multi-resolution spatial fabric in support of Digital Earth ***,DGGSs remain in their infancy with many technical,conceptual,and operational *** renewed interest in DGGS brought on by a recently proposed standard,the demands of big data,and growing needs for monitoring environmental changes across a variety of scales,we seek to highlight current challenges that we see as central to moving the field(s)and technologies of DGGS *** each of the identified challenges,we illustrate the issue and provide a potential solution using a reference DGGS *** articulation of these challenges,we hope to identify a clear research agenda,expand the DGGS research footprint,and provide some ideas for moving forward towards a scaleable Digital Earth *** such challenges helps the GIScience research community to achieve the real benefits of DGGS and provides DGGS an opportunity to play a role in the next generation of GIS.

关键词： DGGS discrete global grid systems GIScience Digital Earth

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