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Physico-chemical properties and macrofauna of soils under various farming systems of cold arid region in Balochistan,Pakistan

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Journal of Mountain Science 2024年第8期21卷 2618-2630页

作者： KHAN Mehmood GUL Shamim KAKAR Hidayatullah PANEZAI Sanaullah KHAN Nayab ZIAD Tariq NASEEM mahrukh shaheen Umbreen Department of Botany University of BalochistanQuetta 87300Pakistan Department of Natural Resource Sciences McGill University21111 Lakeshore Road Ste.Anne de BellevueQuébec H9X 3V9Canada Directorate of Agriculture Research Soil and Water TestingAgricultural Research InstituteQuetta 87300Pakistan Department of Geography and Regional Planning University of BalochistanQuetta 87300Pakistan Department of Zoology University of BalochistanQuetta 87300Pakistan

Barshore is a small village in the Pishin District,Balochistan,Pakistan,with dry summers and cold rainy *** is an agrarian region,mostly with orchards of various fruit *** study investigated the physico-chemical properties and macrofauna of soils under various agricultural management practices of this *** concentrations of soil organic matter(SOM),soil organic carbon(SOC),nutrients,pH,electrical conductivity,soil texture,and the abundance and number of species of soil macrofauna of the agricultural fields were *** agricultural fields were *** fields were orchards of apple,apricot or the mixture of apple and apricot trees and one field was a cropland,cultivated with wheat as a *** orchards were under conservation agricultural practices;whereas,the cropland was under conventional *** agricultural lands were 2-26 years *** concentration of soil organic matter(SOM)in the upper 0-10 cm depth of these field sites ranged from 11.6 g kg^(-1)to 32.8 g kg^(-1)*** compared to cropland,orchards had significantly higher concentration of SOM and SOC.A total of 18 soil macrofauna species were found and the most common and abundant were ants(Monomorium minimum,Camponotus pennsylvanicus,Solenopsis invicta,and Lasius niger)followed by Arion ssp.(Brown Slug)and earthworm Lumbricus *** analysis revealed non-significant relationship of the age and the concentration of SOM with the number of macrofauna species and with the concentrations of total mineral nitrogen,bioavailable phosphorus and *** existence of ants had no relationship with the concentration of SOM;whereas,existence of Lumbricus terrestris tended to had a positive relationship with the concentration of *** field of tree-based intercropping system was 2 years of age since the land was converted from rangeland to a cropland,had two ant species *** indicates the positive influence of crop diversification on soil

关键词： Soil organic matter Macrofauna Land use history Tree-based intercropping Conservation agriculture

Performance Analysis of ZF and RZF in Low-Resolution ADC/DAC Massive MIMO Systems

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China Communications 2024年第8期21卷 115-126页

作者： Talha Younas Shen Jin Muluneh Mekonnen Gao Mingliang Saqib Saleem Sohaib Tahir mahrukh Liaqat School of Electrical and Electronic Engineering Shandong University of TechnologyZibo 255000China Department of Electrical and Computer Engineering COMSATS University IslamabadSahiwal Campus Department of Electrical and Computer Engineering College of EngineeringDhofar UniversitySalalah 211Oman Department of Electrical and Computer Engineering Addis Ababa Science and Technology UniversityAddis AbabaEthiopia Department of Electrical Engineering College of Electrical and Mechanical EngineeringNUSTIslamabadPakistan

Large number of antennas and higher bandwidth usage in massive multiple-input-multipleoutput(MIMO)systems create immense burden on receiver in terms of higher power *** power consumption at the receiver radio frequency(RF)circuits can be significantly reduced by the application of analog-to-digital converter(ADC)of low *** this paper we investigate bandwidth efficiency(BE)of massive MIMO with perfect channel state information(CSI)by applying low resolution ADCs with Rician *** start our analysis by deriving the additive quantization noise model,which helps to understand the effects of ADC resolution on BE by keeping the power constraint at the receiver in *** also investigate deeply the effects of using higher bit rates and the number of BS antennas on bandwidth efficiency(BE)of the *** emphasize that good bandwidth efficiency can be achieved by even using low resolution ADC by using regularized zero-forcing(RZF)combining *** also provide a generic analysis of energy efficiency(EE)with different options of bits by calculating the energy efficiencies(EE)using the achievable *** emphasize that satisfactory BE can be achieved by even using low-resolution ADC/DAC in massive MIMO.

关键词： low-bit analog-digital converter massive(multiple-input-multiple-output)MIMO minimum mean square error(MMSE) regularized zero forcing zero forcing

The role of predictive and prognostic values of inflammatory markers in acute pancreatitis:a narrative review

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Journal of Pancreatology 2024年第1期7卷 72-85页

作者： Saira Rafaqat Aqsa Sattar Farhan Anjum mahrukh Gilani Sana Rafaqat Department of Zoology(Molecular Physiology) Lahore College for Women UniversityLahorePakistan Institute of Zoology University of the PunjabQuaid-i-Azam CampusLahorePakistan Department of Zoology Lahore College for Women UniversityLahorePakistan Department of Biotechnology(Human Genetics) Lahore College for Women UniversityLahorePakistan

Pancreatitis is an inflammatory condition affecting the pancreas and is classified into 2 types,acute and chronic,which can manifest in various *** review article summarizes the role of predictive and prognostic values of inflammatory markers in the pathogenesis of acute pancreatitis,mainly focused on preclinical and clinical *** includes serum amyloid A(SAA),monocyte chemotactic protein-1(MCP-1),erythrocyte sedimentation rate(ESR),interleukin-6(IL-6),C-reactive protein(CRP),IL-10,myeloperoxidase,pentraxin 3,and plasminogen activator inhibitor ***3 plays a crucial role in developing acute pancreatitis by triggering a receptor-interacting protein 3-dependent necroptosis pathway in acinar *** SAA3 could be a potential strategy for treating acute *** recruitment of monocytes/macrophages and the activation of the systemic MCP-1 signaling pathway play a role in the progression of pancreatitis,and blocking MCP-1 may have a suppressive effect on the development of pancreatic *** ESR can predict severe acute pancreatitis with slightly lower accuracy than *** ESR and CRP levels are combined at 24 hours,they predict severe acute pancreatitis ***-6 plays a crucial role in activating the Janus kinase/signal transducers and activators of the transcription pathway,exacerbating pancreatitis and contributing to the initiation and progression of pancreatic *** IL-10 plays a crucial role in controlling the regenerative phase and limiting the severity of fibrosis and glandular atrophy induced by repeated episodes of acute pancreatitis in *** predictive and diagnostic roles of these inflammatory factors in pancreatitis were introduced in detail in this review.

关键词： Acute pancreatitis Inflammatory markers Pathogenesis

Neural stem cell-based in vitro bioassay for the assessment of neurotoxic potential of water samples

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Journal of Environmental Sciences 2021年第3期33卷 72-86页

作者： Muhammad Irfan Masood Natalie Tamara Hauke Muhammad Jawad Nasim Muhammad Sarfraz mahrukh Naseem Karl Herbert Schäfer Division of Bioorganic Chemistry School of PharmacySaarland UniversityD-66123 SaarbrückenGermany Applied Life Sciences University of Applied Sciences Kaiserslautern66482 ZweibrückenGermany ENS Group University of Applied Sciences Kaiserslautern66482 ZweibrückenGermany Abwasserverband Bergstrasse Altau 1069469 WeinheimGermany Institute of Pharmaceutical Sciences University of Veterinary and Animal Sciences54000 LahorePakistan Department of Zoology University of BalochistanQuetta 87550Pakistan

Intensive agriculture activities,industrialization and growing numbers of wastewater treatment plants along river banks collectively contribute to the elevated levels of neurotoxic pollutants in natural water reservoirs across *** established an in vitro bioassay based upon neural stem cells isolated from the subventricular zone of the postnatal mouse to evaluate the neurotoxic potential of raw wastewater,treated sewage effluent,groundwater and drinking *** toxic potential of water samples was evaluated employing viability,proliferation,differentiation and migration *** found that raw wastewater could reduce the viability and proliferation of neural stem cells,and decreased the neuronal and astrocyte differentiation,neuronal neurite growth,astrocyte growth and cell *** sewage water also showed inhibitory effects on cell proliferation and *** results indicated that relatively high concentrations of nitrogenous substances,pesticides,mercuric compounds,bisphenol-A,and phthalates,along with some other pollutants in raw wastewater and treated sewage water,might be the reason for the neuroinhibitory effects of these water *** model successfully predicted the neurotoxicity of water samples collected from different sources and also revealed that the incomplete removal of contaminants from wastewater can be problematic for the developing nervous *** presented data also provides strong evidence that more effective treatments should be used to minimize the contamination of water before release into major water bodies which may be considered as water reservoirs for human usage in the future.

关键词： Neural stem cells Subventricular zone Neurotoxicity Bioassay Treated sewage effluents Pesticides

粉末中C抑制FeAl熔滴氧化机制及其对等离子喷涂层组织与性能的影响

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中国表面工程 2023年第1期36卷 44-56页

作者：周哲张黎董昕远雒晓涛 mahrukh M 李长久西安交通大学金属材料强度国家重点实验室西安710049 NED工程技术大学机械工程系巴基斯坦

大气等离子喷涂(APS)金属时,熔滴不可避免地发生氧化是难以获得粒子间结合充分的致密涂层的主要原因。以FeAl金属间化合物为例,提出一种在粉末中添加亚微米金刚石颗粒引入碳源,以期利用碳在高温下优先氧化的特性抑制等离子喷涂飞行粒子... 详细信息

大气等离子喷涂(APS)金属时,熔滴不可避免地发生氧化是难以获得粒子间结合充分的致密涂层的主要原因。以FeAl金属间化合物为例,提出一种在粉末中添加亚微米金刚石颗粒引入碳源,以期利用碳在高温下优先氧化的特性抑制等离子喷涂飞行粒子中Fe、Al元素的氧化,获得无氧化物的高温熔滴从而制备低氧含量(质量分数)、粒子间充分结合的FeAl金属间化合物涂层的新方法。采用APS制备Fe Al涂层,研究金刚石的添加对涂层氧含量、碳含量、涂层内粒子间结合质量与硬度的影响规律,探讨FeAl熔滴飞行中的氧化行为。采用商用热喷涂粒子诊断系统测量APS喷涂中的粒子温度,通过SEM与XRD表征了涂层的组织结构,并表征涂层的结合强度与硬度。结果表明,在等离子射流的加热和Fe、Al元素放热反应的联合作用下,飞行中FeAl熔滴的表面温度可达2 000℃以上,满足C原位脱氧的热力学条件。与不含碳的传统Fe Al涂层中的氧含量随喷涂距离的增加而显著增加的规律完全不同,用Fe/Al/2.5C粉末喷涂时涂层中的氧含量随距离的增加而减小,表明飞行中熔滴的氧化得到抑制,实现了C原位脱氧抑制金属元素氧化的自清洁氧化物的效应。FeAl/2.5C涂层氧含量由传统FeAl涂层的3.67 wt.%显著降至0.62 wt.%以下,涂层中有限的氧化物主要来源于粒子沉积后氧化。因Fe Al/2.5C熔滴温度超过2 100℃,实现了熔滴碰撞引起同质涂层粒子表面熔化的自冶金结合效果,提升了涂层的致密性,其表观孔隙率由2.2%降至0.28%;涂层结合强度高于59.2 MPa,且因涂层由FeAl相及Fe3AlCx渗碳体相组成,其硬度达到590 HV0.3,约为传统Fe Al涂层的2倍。

关键词：大气等离子喷涂 FeAl/2.5C涂层组织与性能原位脱氧自冶金结合

Stevenleaf from Gynostemma Pentaphyllum inhibits human hepatoma cell(HepG2)through cell cycle arrest and apoptotic induction

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Food Science and Human Wellness 2020年第3期9卷 295-303页

作者： Sayed Sajid Hussain Fan Zhang Yuanyuan Zhang Kiran Thakur mahrukh Naudhani Carlos L.Cespedes-Acuna Zhaojun Wei School of Food Science and Biological Engineering Hefei University of TechnologyHefei230009China Department of Basic Sciences Research Group in Chemistry and Biotechnology of Bioactive Natural ProductsFaculty of SciencesUniversity of Bio-BioAndres Bello AvenueChillanChile College of Biological Science and Technology Fuzhou UniversityFuzhou350108China Biological Science and Engineering College North Minzu UniversityYinchuan750021China

The anticancer activity of stevenleaf(SV)on the basis of cell viability,cell cycle,and apoptosis induction in HepG2 cancer cells were *** controlled the growth of HepG2 cells with IC50 of 139.82μmol/L for 24 h,IC50 of 119.12μmol/L for 48 h and cell cycle arrested at G0/G1 phase,induced cell apoptosis and enhanced intracellular ROS *** cell cycle arrest,the mRNA expression levels of p21,p27 and p53 were up-regulated,while the expression levels of Cyclin A,Cyclin D1,Cyclin E and CDK1/2 were *** efficiently up-regulated TNF R1,TRADD1 and FADD and down-regulated Caspase8 for cell death receptors;similarly,up-regulated Bax,Bak,Cytc,Apaf1,Caspase3 and Caspase9,and down-regulated Bcl2,Bcl xl and Bad for mitochondrial signal *** induced the mTOR-mediated cell apoptosis in HepG2 cells via activation of Akt and *** mechanistic explanation for the anticancer activity of SV as functional food can be derived from above results.

关键词： Gynostemma Pentaphyllum Stevenleaf HepG2 cell Cell cycle Apoptosis

Downregulation of nc886 contributes to prostate cancer cell invasion and TGFβ1-induced EMT

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Genes & Diseases 2022年第4期9卷 1086-1098页

作者： Ronghui Yang Lingkun Zuo Hui Ma Ying Zhou Ping Zhou Liyong Wang Miao Wang mahrukh Latif Lu Kong Department of Biochemistry and Molecular Biology Capital Medical UniversityBeijing 100069PR China Biomedical Engineering Institute of Capital Medical University Capital Medical UniversityBeijing 100069PR China Department of Pathology Beijing Friendship HospitalThe Second Clinical Medical College of Capital Medical UniversityBeijing 100050PR China Department of Nuclear Medicine Fourth Hospital of Hebei Medical UniversityShijiazhuangHebei 050010PR China

Epithelial-to-mesenchymal transition (EMT) activation is important in cancer progression and metastasis. Evidence indicates that nc886 is a representative Pol III gene that processes microRNA products via Dicer and further downregulates its target gene transforming growth factor- β1 (TGF-β1), which is the most prominent inducer of EMT in prostate cancer (PC). Consistent with the previous literature, we found that nc886 downregulation was strongly associated with metastatic behavior and showed worse outcomes in PC patients. However, little is known about the association between nc886 and the EMT signaling pathway. We developed a PC cell model with stable overexpression of nc886 and found that nc886 changed cellular morphology and drove MET. The underlying mechanism may be related to its promotion of SNAIL protein degradation via ubiquitination, but not to its neighboring genes, TGFβ-induced protein (TGFBI) and SMAD5, which are Pol II-transcribed. TGF-β1 also override nc886 promotion of MET via transient suppression the transcription of nc886, promotion of TGFBI or increase in SMAD5 phosphorylation. Both nc886 inhibition and TGFBI activation occur regardless of their methylation status. The literature suggests that MYC inhibition by TGF-β1 is attributed to nc886 downregulation. We incidentally identified MYC-associated zinc finger protein (MAZ) as a suppressive transcription factor of TGFBI, which is controlled by TGF-β1. We elucidate a new mechanism of TGF-β1 differential control of Pol II and the transcription of its neighboring Pol III gene and identify a new EMT unit consisting of nc886 and its neighboring genes.

关键词： EMT MET Non-coding RNA Prostate cancer TGF-β1

B清除大气等离子喷涂CuNi熔滴氧化物效应

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金属学报 2022年第2期58卷 206-214页

作者：任媛董昕远孙浩雒晓涛李成新 M.mahrukh 李长久西安交通大学金属材料强度国家重点实验室西安710049

提出了粉末中添加B的成分设计,实现通过B牺牲氧化而保护合金元素不氧化从而发展高温CuNi熔滴自清洁氧化物效应。采用CuNi2B与CuNi4B 2种粉末,通过大气等离子喷涂工艺制备涂层,通过SEM、EDS、XRD和ICP-OES等方法研究了B含量与喷涂距离对C... 详细信息

提出了粉末中添加B的成分设计,实现通过B牺牲氧化而保护合金元素不氧化从而发展高温CuNi熔滴自清洁氧化物效应。采用CuNi2B与CuNi4B 2种粉末,通过大气等离子喷涂工艺制备涂层,通过SEM、EDS、XRD和ICP-OES等方法研究了B含量与喷涂距离对CuNi涂层组织结构与性能的影响。结果表明,熔滴可加热至1900℃以上,粉末中B的引入可抑制飞行中高温熔滴中的合金元素的氧化,从而显著降低CuNi涂层中的O含量,而该效果受熔滴中B含量影响显著。采用4%B的CuNi合金粉末时,随着喷涂距离的增加,涂层中的氧化物显著降低,涂层中的O主要由熔滴沉积后的氧化引入,优化喷涂工艺制备的涂层O含量降低至0.43%,显著低于CuNiIn涂层的3.5%。当CuNi粉末含B为1.83%时,在距离超过100 mm,B含量降至0.5%以下时,不足以抑制等离子喷涂过程中飞行颗粒的合金元素氧化,故实现高温熔滴氧化保护的临界B含量约为0.5%。研究发现,B添加可引起合金熔点降低效应与去氧化物净化效应,从而显著增强了CuNi粒子间的冶金结合,提高了涂层的致密性;涂层B含量随粉末成分与工艺参数从0.26%增加至3.61%,而CuNi涂层硬度则随B含量增加从151 HV_(0.2)线性增加至457 HV_(0.2)。

关键词： CuNiIn涂层 CuNiB涂层组织与性能层间结合自熔效应等离子喷涂

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基于聚类方法的高压架空输电线路故障预测

基于聚类方法的高压架空输电线路故障预测

作者： mahrukh Ansari 华北电力大学(北京)

学位级别：硕士

输电线路是确保电力系统可靠性和安全运行的重要组成部分。输电线路故障直接威胁电网安全运行,造成事故和停电。对输电线路运行状况的精确预测和准确评估,可以为国民经济建设提供技术支持,为电力系统提高效率。架空输电线路的运行状态... 详细信息

输电线路是确保电力系统可靠性和安全运行的重要组成部分。输电线路故障直接威胁电网安全运行,造成事故和停电。对输电线路运行状况的精确预测和准确评估,可以为国民经济建设提供技术支持,为电力系统提高效率。架空输电线路的运行状态受运行条件和天气条件的影响,输电线路中断的主要原因是大风、冰冻、雷电等恶劣天气。已有的输电线路故障预测研究的局限性在于来自线上监测系统的不完整监测数据,在于难以预料的气候状况的突发变化,在于预测研究需要一定数量的历史输电线路故障数据。在此基础上,本论文从恶劣天气条件下的未知因素的着手,提出一种方法来计算天气和故障的相关性对输电线路故障情况的影响。本论文工作在完整的线上监控系统数据的基础上,研究了传输线故障预测问题。基于主成分分析法和K均值聚类算法,本论文修正了一种无监督机器学习方法。首先利用主成分分析法消除影响较小的因素,并减小数据维度,然后用K均值法构建聚类模型,通过测量中心到最远点之间的距离来预测天气造成的输电线故障的情况。为了对比分析聚类仿真的结果,又采用其它两种无监督学习算法——单类支持向量机方法和孤立森林法用来获得对比的聚类结果和模型精度。最后通过对比表明,当考虑到均值和标准偏差时,K均值聚类法和孤立森林法的误差基本近似于1%,单类支持向量机方法误差较大。通过仿真说明K均值法和孤立森林法的结果非常近似,都适用于本研究问题。

关键词：输电线路主成分分析法无监督机器学习 K均值聚类单类支持向量机法孤立森林法