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Extent of lymphadenectomy has no impact on postoperative complications after gastric cancer surgery in Sweden

Chinese Journal of Cancer Research 2017年第4期29卷 313-322页

作者： chih-han kung huan song weimin ye magnus nilsson jan johansson ioannis rouvelas tomoyuki irino lars lundell jon a tsai mats lindblad department of clinical science intervention and technology(clintec)division of surgerykarolinska institutet171 77 StockholmSweden department of surgery skelleftea county hospital931 86 SkellefreaSweden department of medical epidemiology and biostatistics karolinska institutet171 77 StockholmSweden section of esophagogastric surgery centre for digestive diseaseskarolinska university hospital141 86 StockholmSweden department of surgery skane university hospital and lund universityfaculty of medicinedepartment of clinical sciences221 00 LuridSweden

Objective： Curative gastric cancer surgery entails removal of the primary tumor with adequate margins including regional lymph nodes. European randomized controlled trials with recruitment in the 1990＇s reported increased morbidity and mortality for D2 compared to D 1. Here, we examined the extent of lymphadenectomy during gastric cancer surgery and the associated risk for postoperative complications and mortality using the strengths of a population-based study. Methods： A prospective nationwide study conducted within the National Register of Esophageal and Gastric Cancer. All patients in Sweden from 2006 to 2013 who underwent gastric cancer resections with curative intent were included. Patients were categorized into DO, D I, or D I ＋/D2, and analyzed regarding postoperative morbidity and mortality using multivariable logistic regression. Results： In total, 349 （31.7%） patients had a DO, 494 （44.9%） DI, and 258 （23.4%） DI＋/D2 lymphadenectomy. The 30-d postoperative complication rates were 25.5%, 25.1% and 32.2 % （DO, D I and D1 ＋/D2, respectively）, and 90-d mortality rates were 8.3%, 4.3 % and 5.8%. After adjustment for confounders, in mukivariable analysis, there were no significant differences in risk for postoperative complications between the lymphadenectomy groups. For 90-d mortality, there was a lower risk for D1 vs. DO. Conclusions： The majority of gastric cancer resections in Sweden have included only a limited lymphadenectomy （DO and DI）. More extensive lymphadenectomy （DI＋/D2） seemed to have no impact on postoperative morbidity or mortality.

关键词： Gastric cancer lymphadenectomy national database mortality complications

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A comparison of process performance during the anaerobic mono-and co-digestion of slaughterhouse waste through different operational modes

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Journal of Environmental Sciences 2018年第2期30卷 149-156页

作者： Jhosané Pagés-Díaz Ileana Pereda-Reyes Jose Luis Sanz magnus Lundin Mohammad J.Taherzadeh Ilona Sárvári Horváth Process Engineering Centre (CIPRO) Universidad Tecnológica de La Habana "José Antonio Echeverría" (Technical University of Havana "José A. Echeverría") (Cujae) Swedish Centre for Resource Recovery University of Bor?s Department of Molecular Biology Autonomous University of Madrid

The use of consecutive feeding was applied to investigate the response of the microbial biomass to a second addition of substrates in terms of biodegradation using batch tests as a promising alternative to predict the behavior of the process. Anaerobic digestion（AD） of the slaughterhouse waste（SB） and its co-digestion with manure（M）, various crops（VC）, and municipal solid waste were evaluated. The results were then correlated to previous findings obtained by the authors for similar mixtures in batch and semi-continuous operation modes. AD of the SB failed showing total inhibition after a second feeding. Co-digestion of the SB ＋ M showed a significant improvement for all of the response variables investigated after the second feeding, while co-digestion of the SB ＋ VC resulted in a decline in all of these response variables. Similar patterns were previously detected, during both the batch and the semi-continuous modes.

关键词： Co-digestion Biomethane potential test Second feeding Specific methanogenic activity Slaughterhouse waste

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Thrips Pests of China and The United States

Thrips Pests of China and The United States

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第三届全国生物入侵大会

作者： Zhon-gren Lei Stuart R Reitz State Key Laboratory of Plant Disease and Insect Pests Institute for Plant ProtectionChinese Academy of Agricultural Sciences BeijingChina Center for Medical Agricultural and Veterinary EntomologyAgricultural Research Service USDA 6383 Mahan Dr.TallahasseeFL 32308-1410 USA

Thrips are among the most important agricultural pests globally because of the damage inflicted by their oviposition,feeding,and ability to transmit plant *** of their invasiveness,a number of pest species are common to both China and the United States and present significant challenges to growers of a wide range of crops in both *** the pest thrips common to both countries are four of the major global thrips pests,Frankliniella occidentalis(Pergande), Scirtothrips dorsalis Hood,Thrips palmi Karny,and Thrips tabaci *** review addresses characteristics that enable to thrips to be such damaging pests and how biological attributes of thrips create challenges for their *** these challenges,a number of successful management tactics have been developed for various cropping *** discuss some of these tactics that have been developed,including the use of cultural controls,biological controls,and judicious use of insecticides that do not disrupt overall pest management *** exchange of this type of information will help to facilitate management of pest thrips,especially in regions where species have recently invaded.A prime example is ***,the western flower thrips,which is native to the United ***,management tactics developed in the United States can be adapted to China,where *** is a recent invader that is *** further success in management of thrips requires a thorough understanding of thrips ecology,we discuss areas of future research and emphasize the importance of collaboration among different countries to enhance our overall understanding of the biology and ecology of thrips and to improve management programs for these pests.

关键词： Thrips Tospovirus Invasive Integrated pest management

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A highly selective C-rhamnosyltransferase from Viola tricolor and insights into its mechanisms

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Acta Pharmaceutica Sinica B 2023年第8期13卷 3535-3544页

作者： Bo-Yun Han Zi-Long Wang Junhao Li Qing Jin Hao-Tian Wang Kuan Chen Yang Yi Hansgren Xue Qiao Min Ye State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesPeking UniversityBeijing 100191China Department of Physics and Astronomy Uppsala UniversityUppsala SE-75120Sweden College of Life Science Anhui Agricultural UniversityHefei 230036China Peking University-Yunnan Baiyao International Medical Research Center Beijing 100191China

C-Glycosides are important natural products with various *** plant biosynthetic pathways,the C-glycosylation step is usually catalyzed by C-glycosyltransferases(CGTs),and most of them prefer to accept uridine 5’-diphosphate glucose(UDP-Glc)as sugar *** CGTs favoring UDP-rhamnose(UDP-Rha)as sugar donor has been reported,thus ***,we report the first selective C-rhamnosyltransferase VtCGTc from the medicinal plant Viola *** could efficiently catalyze C-rhamnosylation of 2-hydroxynaringenin 3-C-glucoside,and exhibited high selectivity towards *** for the sugar donor selectivity of VtCGTc were investigated by molecular dynamics(MD)simulations and molecular mechanics with generalized Born and surface area solvation(MM/GBSA)binding free energy ***144 played a vital role in recognizing UDP-Rha,and the V144T mutant could efficiently utilize *** work provides a new and efficient approach to prepare flavonoid C-rhamnosides such as violanthin and iso-violanthin.

关键词： Flavonoid C-glycoside C-rhamnosyltransferase Biosynthesis Catalytic mechanisms Sugardonorselectivity

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Characterisation of a novel, multifunctional, co-processed excipient and its effect on release profile of paracetamol from tablets prepared by direct compression

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Asian Pacific Journal of Tropical Biomedicine 2015年第9期5卷 739-742页

作者： Eraga Sylvester Okhuelegbe Arhewoh Matthew Ikhuoria Uhumwangho Michael Uwumagbe Iwuagwu magnus Amara Department of Pharmaceutics and Pharmaceutical Technology Faculty of Pharmacy University of Benin

Objective: To characterise a novel multifunctional pharmaceutical excipient and investigate its ef ect on paracetamol release from tablets prepared by direct ***: The excipient was prepared by co-processing gelatinized maize starch with sodium carboxymethyl cellulose and microcrystalline cellulose in a ratio of 2:1:1, dried and pulverized into powder. The excipient formulated was characterized using Fourier transform infrared spectroscopy and dif erential scanning calorimetry. The excipient was used to prepare batches of tablets by direct compression with drug-excipient ratios of 1:1, 1:2, 1:3 and 1:4. Parameters evaluated on tablets include crushing strength, friability and in vitro dissolution studies. Results: Differential scanning calorimetry analysis revealed a crystalline excipient while Fourier transform infrared spectroscopy showed no interaction between the excipient and paracetamol. Tablets from all the batches gave average crushing strength values between 3.47 and 4.88 kp. The 1:1 and 1:2 tablet batches were comparable to each other while 1:3 and 1:4 were also comparable to one another in their dissolution proi les. The dissolution parameters of the 1:4 batch was faster with- m∞(90.5%), t50%(3.5 min), t70%(11.6 min) while that of ratio 1:1 was the least with- m∞(48.6%), m5min(23.8%). Their release kinetics followed a KorsmeyerPeppas model with a super case-II transport ***: The drug-excipient ratios of 1:3 and 1:4 gave pharmaceutically acceptable tablets that met the British Pharmacopoeia specii cations. The t50% value of the 1:4 batch of tablets may i nd its usefulness in formulating drugs for which a fast onset of action is desired.

关键词： Co-processed excipient Dissolution proiles Paracetamol tablet Direct compression

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In Situ Etching for Total Control Over Axial and Radial Nanowire Growth

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Nano Research 2010年第4期3卷 264-270页

作者： magnus T.Borgström Jesper Wallentin Johanna Trägårdh Peter Ramvall Martin Ek LReine Wallenberg Lars Samuelson Knut Deppert Solid State Physics Lund UniversityBox 118S-22100LundSweden Polymer&Materials Chemistry/nCHREM Lund UniversityS-22100 LundSweden H.H.Wills Physics Laboratory University of BristolTyndall AvenueBristol BS81TLUnited Kingdom

We report a method using in situ etching to decouple the axial from the radial nanowire growth pathway,independent of other growth *** a wide range of growth parameters can be explored to improve the nanowire properties without concern of tapering or excess structural defects formed during radial *** demonstrate the method using etching by HCl during InP nanowire *** improved crystal quality of etched nanowires is indicated by strongly enhanced photoluminescence as compared to reference nanowires obtained without etching.

关键词： MOVPE nanowire growth in situ etching photoluminescence

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自有操作系统为何重要? 梅赛德斯—奔驰技术高层对谈

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汽车之友 2023年第4期 76-79页

作者：纳森 Markus Schafer magnus Ostberg 不详梅赛德斯-奔驰集团股份公司董事会梅赛德斯-奔驰集团股份公司

2023年2月23日,梅赛德斯-奔驰发布了打造自有操作系统***的具体计划。据悉,这一操作系统将在本年代中期伴随全新模块化车型架构,即MMA平台一同推出。自有操作系统到底优势何在?建立自有操作系统为何成为当今汽车技术领域的主流趋势之一... 详细信息

2023年2月23日,梅赛德斯-奔驰发布了打造自有操作系统***的具体计划。据悉,这一操作系统将在本年代中期伴随全新模块化车型架构,即MMA平台一同推出。自有操作系统到底优势何在?建立自有操作系统为何成为当今汽车技术领域的主流趋势之一?梅赛德斯-奔驰又为自身的***操作系统设立了哪些预期?

关键词：操作系统梅赛德斯模块化主流趋势 OS

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A comparative UV-HPLC analysis of ten brands of ibuprofen tablets

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Asian Pacific Journal of Tropical Biomedicine 2015年第10期5卷 880-884页

作者： Sylvester Okhuelegbe Eraga Mathew Ikhuoria Arhewoh Rosemary Ngozi Chibuogwu magnus Amara Iwuagwu Department of Pharmaceutics and Pharmaceutical Technology Faculty of Pharmacy University of Benin

Objective: To investigate the pharmaceutical equivalence of ten brands of ibuprofen tablets(400 mg) purchased from pharmacies in Benin City, ***: The drug samples were subjected to uniformity of weight, crushing strength,friability, melting point, disintegration and dissolution tests following acceptable and official protocols. The ibuprofen content was determined using UV and high performance liquid chromatography ***: Crushing strength values of the drug samples ranged between 6 and 16 kp while the disintegration times were between 7.43 and 10.40 min(for uncoated tablets) and3.25–37.32 min(for coated tablets). Friability values were less than 1% and the melting points of recrystallized ibuprofen from the samples ranged from 73.5 to 76.0 C. The amount of ibuprofen released within 1 h ranged between 18% and 102% and two brands failed the content of active ingredient in the UV method of assay while all the brands passed the test using ***: Ibuprofen(400 mg) tablets marketed in Benin City, Nigeria vary in pharmaceutical quality.

关键词： pharmaceutical tablets ingredient passed melting d

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Redundancy and Response Diversity of Functional Groups:Implications for the Resilience of Coral Reefs

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AMBIO－人类环境杂志 2006年第1期35卷 30-35页

作者： magnus Nystrǒm 梁虹（译）瑞典斯德哥尔摩大学系统生态学系和交叉学科环境研究中心不详

对多尺度功能群生物多样性的深入了解有助于珊瑚礁管理的加强。本文主要分析了功能群内多样性在保护有利于珊瑚礁状况复原的重要生态系统过程中的作用。对于与生态系统复原有关的两个重要的物种多样性指标：功能丰余性和功能群内对变化... 详细信息

对多尺度功能群生物多样性的深入了解有助于珊瑚礁管理的加强。本文主要分析了功能群内多样性在保护有利于珊瑚礁状况复原的重要生态系统过程中的作用。对于与生态系统复原有关的两个重要的物种多样性指标：功能丰余性和功能群内对变化的反应多样性进行了分析，采用了三个重要的功能群来演示这两个指标之间的相互关系．以及它们在珊瑚礁复原过程中的作用：虫黄藻（珊瑚虫的共生微藻）、造礁珊瑚和草食动物。对功能丰余性和反应多样性破坏的后果进行了进一步研究，对保护珊瑚礁复原过程中关键的生态过程策略进行了探讨。

关键词：生物多样性珊瑚礁功能群复原反应生态系统过程多样性指标两个指标草食动物生态过程

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Waste Tire Rubber-based Refrigerants for Solid-state Cooling Devices

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Chinese Journal of Polymer Science 2020年第7期38卷 769-775,I0007页

作者： Nicolau Molina Born Erik Oda Usuda Mariana da Silva Gigliotti Denílson JoséMarcolino de Aguiar William Imamura Lucas Soares Paixao Alexandre magnus Gomes Carvalho Catalan Institute of Nanoscience and Nanotechnology(ICN2) 08860BellaterraBarcelonaSpain The Institute of Photonic Sciences(ICFO) 08193CastelldefelsBarcelonaSpain Universidade Federal de Sāo Paulo(UNIFESP) 00972-270DiademaSPBrazil Instituto de Física"Gleb Wataghin" Universidade Estadual de Campinas(UNICAMP)13083-970CampinasSPBrazil Universidade Tecnológica Federal do Paraná(UTFPR) 84017-220Ponta GrossaPRBrazil Faculdade de Engenharia Mec(a)nica Universidade Estadual de Campinas(UNICAMP)13083-860CampinasSPBrazil Departamento de Engenharia Mec(a)nica Universidade Estadual de Maringá(UEM)870-900MaringáPRBrazil

Management of discarded tires is a compelling environmental issue *** there are several approaches developed to recycle waste tire rubbers,their application in solid-state cooling is still *** the high barocaloric potential verified for elastomers,the use of waste tire rubber(WTR)as a refrigerant in solid-state cooling devices is very ***,we investigated the barocaloric effects in WTR and polymer blends made of vulcanized natural rubber(VNR)and WTR,to evaluate its feasibility for solid-state cooling *** adiabatic temperature changes and the isothermal entropy changes reach giant values,as well as the performance parameters,being comparable or even better than most barocaloric materials in ***,pure WTR and WTR-based samples also present a faster thermal exchange than VNR,consisting of an additional advantage of using these discarded ***,the present findings evidence the encouraging perspectives of employing waste rubbers in solid-state cooling based on barocaloric effects,contributing to both the recycling of polymers and the sustainable energy technology field.

关键词： Waste tire rubber Solid-state cooling Barocaloric effect Tire recycling Sustainable energy

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