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Managing Cases with Human Immunodeficiency Virus Infection: Knowing the Dynamics from Voluntary Counselling and Testing Clients in Bobo-Dioulasso for Better Planning in Burkina Faso (1996-2014)

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Advances in Infectious Diseases 2019年第2期9卷 137-149页

作者： Armel Poda M’winmalo Ines Evelyne Da Ziemlé Clément Méda Serge Somda Arsène Héma Jacques Zoungrana Isidore traoré Apoline Sondo Ismael Diallo Mamadaou Savadogo Issiaka Sombié madina traoré Nicolas Méda Department of Infectious Diseases Souro Sanou Teaching Hospital Bobo-Dioulasso Burkina Faso Centre MURAZ Bobo-Dioulasso Burkina Faso Department of Infectious Diseases Yalgado Ouedraogo Teaching Hospital Ouagadougou Burkina Faso Health Regional Direction of Hauts Bassins Region Bobo-Dioulasso Burkina Faso West African Health Organization (WAHO) Bobo-Dioulasso Burkina Faso Centre Anonyme de Dépistage et d’Information (CADI) Bobo-Dioulasso Burkina Faso

Background: The Anonymous Screening and Information Centre (CADI) is the oldest screening centre of HIV from Burkina Faso. Since its opening, no analysis on the evolution of Human Immunodeficiency Virus (HIV) prevalence has been carried out. Objective: The study aimed to describe the dynamics of HIV infection when managing centres offering voluntary counselling and testing to client, such as the Screening and Counselling Centre (CADI), in Bobo Dioulasso, Burkina Faso. Patients and Methods: A cross-sectional study was performed including people screened at the CADI from May 1996 to June 2014. Pearson khi2 test and Cuzick trend test were used with a 5% significance level. Results: From 7.1% of the 11,451 cases analyzed, the average age of clients screened was 30 ± 10.83 year-old. There was a female predominance (sex ratio = 0.8). The 16.4% (15.7 - 17.1) of the cases from the 11,451 clients included in our study were tested HIV positive. The global prevalence rate of HIV in the centre has significantly decreased from 46.2% in 1996 to 1.5% in 2014 (p Conclusion: The behaviour change could be a justification for the decline in HIV prevalence at the centre, hence the importance of sensitization campaigns.

关键词： Burkina Faso Clients Prevalence HIV Screening Case Management

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Ensemble Approach Combining Deep Residual Networks and BiGRU with Attention Mechanism for Classification of Heart Arrhythmias

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Computers, Materials & Continua 2024年第7期80卷 341-359页

作者： Batyrkhan Omarov Meirzhan Baikuvekov Daniyar Sultan Nurzhan Mukazhanov madina Suleimenova Maigul Zhekambayeva Department of Information Systems Al-Farabi Kazakh National UniversityAlmaty050040Kazakhstan Department of Mathematical and Computer Modeling International Information Technology UniversityAlmaty050040Kazakhstan Department of Software Engineering Satbayev UniversityAlmaty050013Kazakhstan

This research introduces an innovative ensemble approach,combining Deep Residual Networks(ResNets)and Bidirectional Gated Recurrent Units(BiGRU),augmented with an Attention Mechanism,for the classification of heart *** escalating prevalence of cardiovascular diseases necessitates advanced diagnostic tools to enhance accuracy and *** model leverages the deep hierarchical feature extraction capabilities of ResNets,which are adept at identifying intricate patterns within electrocardiogram(ECG)data,while BiGRU layers capture the temporal dynamics essential for understanding the sequential nature of ECG *** integration of an Attention Mechanism refines the model’s focus on critical segments of ECG data,ensuring a nuanced analysis that highlights the most informative features for arrhythmia *** on a comprehensive dataset of 12-lead ECG recordings,our ensemble model demonstrates superior performance in distinguishing between various types of arrhythmias,with an accuracy of 98.4%,a precision of 98.1%,a recall of 98%,and an F-score of 98%.This novel combination of convolutional and recurrent neural networks,supplemented by attention-driven mechanisms,advances automated ECG analysis,contributing significantly to healthcare’s machine learning applications and presenting a step forward in developing non-invasive,efficient,and reliable tools for early diagnosis and management of heart diseases.

关键词： CNN BiGRU ensemble deep learning ECG arrhythmia heart disease

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From food waste to high-capacity hard carbon for rechargeable sodium-ion batteries

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Carbon Resources Conversion 2024年第3期7卷 66-73页

作者： madina Kalibek Lunara Rakhymbay Zhanar Zhakiyeva Zhumabay Bakenov Seung-Taek Myung Aishuak Konarov Department of Chemical and Materials Engineering School of Engineering and Digital SciencesNazarbayev University53 Kabanbay Batyr Ave.AstanaKazakhstan Hybrid Materials Research Center Department of Nanotechnology and Advanced Materials EngineeringSejong Battery InstituteSejong UniversitySeoul 05006South Korea

In this study,we introduce a straightforward and effective approach to produce P-doped hard carbon using coffee grounds as the precursor,with H_(3)PO_(4)serving as the doping *** varying the concentrations of H_(3)PO_(4)(1 M,2 M,and 3 M),we aimed to determine the optimal doping level for maximizing the incorporation of phosphorus ions into the carbon *** investigation revealed that using 2 M of H_(3)PO_(4)as the dopant material for hard carbon led to promising electrochemical performance when employed as an anode material for sodium-ion *** P-doped hard carbon,carbonized at 1300℃,exhibited an impressive reversible capacity of 341 mAh g􀀀1 at a current density of 20 mA g􀀀1,with an initial Coulombic efficiency(ICE)of 83%.This outstanding electrochemical performance of P-doped hard carbon can be attributed to its unique properties,including a porous agglomerated structure,a significant interlayer spacing,and the formation of C-P bonds.

关键词： Coffee waste Hard carbon Phosphorus doping Sodium-ion batteries

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Some Indicators of the Water Regime in Some Varieties Belonging to the Monarda didyma L. Genus in the Conditions of Tashkent (Uzbekistan)

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American Journal of Plant Sciences 2024年第5期15卷 374-386页

作者： Mamadalieva Vakhobjon Kizi madina Rakhimova Tashkhanim Physiology of Plant and Botany Department Biology Faculty National University of Uzbekistan named after Mirzo Ulugbek Tashkent Uzbekistan Institute of Botany of the Academy of Sciences of the Republic of Uzbekistan Tashkent Uzbekistan

In this article, the names of 3 varieties of Monarda didyma L., which are considered to be introduced species, some indicators of the water regime in the climatic conditions of Uzbekistan: the amount of water in the leaves, water deficit, water storage capacity were studied in spring and summer, and seasonal changes were determined. According to these indicators of the water regime, the studied varieties belong to the labile water regime, high green mass (centner), seed yield (how many grams), resistance to diseases and pests have been determined, which shows that it is promising for introduction in the conditions of our republic. Therefore, it is recommended to breed these varieties in the foothills and hilly regions of Uzbekistan, where the amount of precipitation is more than 400 - 500 mm.

关键词： Uzbekistan Tashkent Monarda didyma Bergama Jar-Ptitsa Cambridge Scarlet Water Regime Water Quantity Water Shortage Water Storage Capacity Labile

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Cancer immunotherapy with envelopedself-amplifying mRNA CARG-2020 thatmodulates IL-12,IL-17 and PD-L1 pathways toprevent tumor recurrence

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Acta Pharmaceutica Sinica B 2024年第1期14卷 335-349页

作者： Ju Chen Bhaskara Reddy madina Elham Ahmadi Timur Olegovich Yarovinsky Marie Marthe Krady Eileen Victoria Meehan Isabella China Wang Xiaoyang Ye Elise Pitmon Xian-Yong Ma Bijan Almassian Valerian Nakaar Kepeng Wang Department of Immunology School of MedicineUniversity of Connecticut Health CenterFarmingtonCT 06030USA CaroGen Corporation FarmingtonCT 06030USA The Eighth Clinical Medical College of Guangzhou University of Chinese Medicine Foshan Hospital of Traditional Chinese MedicineFoshan 528000China The Loomis Chaffee School WindsorCT 06095USA

Targeting multiple immune mechanisms may overcome therapy resistance and further improve cancer immunotherapy for ***,we describe the application of virus-like vesicles(VLV)for delivery of three immunomodulators alone and in combination,as a promising approach for cancer *** vectors were designed to deliver single chain interleukin(IL)-12,shorthairpin RNA(shRNA)targeting programmed death ligand 1(PD-L1),and a dominant-negative form of IL-17 receptor A(dn-IL17RA)as a single payload or as a combination *** delivery of the VLV vector expressing IL-12 alone,as well as the trivalent vector(designated CARG-2020)eradicated large established ***,only CARG-2020 prevented tumor recurrence and provided long-term survival benefit to the tumor-bearing mice,indicating a benefit of the combined *** abscopal effects of CARG-2020 on the non-injected contralateral tumors,as well as protection from the tumor cell re-challenge,suggest immune-mediated mechanism of protection and establishment of immunological ***,CARG-2020 potently activates Th1 immune mechanisms and inhibits expression of genes related to T cell exhaustion and cancer-promoting *** ability of CARG-2020 to prevent tumor recurrence and to provide survival benefit makes it a promising candidate for its development for human cancer immunotherapy.

关键词： Virus-like vesicles Oncolytic virus IL-12 IL-17 PD-L1 T cell exhaustion Combination therapy Cancer immunotherapy

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“目标—行动—反馈”框架下Z县脱贫攻坚到乡村振兴的衔接路径——基于产业发展的视角

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新疆大学学报（哲学社会科学版） 2024年第4期52卷 93-102页

作者：麦迪娜·吐逊江杨瑶中国人民大学公共管理学院北京100872

脱贫攻坚到乡村振兴的有效衔接是建成社会主义现代化新农村,实现中国式现代化的关键所在,然而,该问题在目前阶段仍然面临着理论与实践的挑战。基于解答疑问和应对挑战的内在逻辑驱动,文章首先梳理了从脱贫攻坚转向乡村振兴的宏观政策背... 详细信息

脱贫攻坚到乡村振兴的有效衔接是建成社会主义现代化新农村,实现中国式现代化的关键所在,然而,该问题在目前阶段仍然面临着理论与实践的挑战。基于解答疑问和应对挑战的内在逻辑驱动,文章首先梳理了从脱贫攻坚转向乡村振兴的宏观政策背景,揭示了有效衔接的重要性和必要性;其次在“目标—过程—反馈”的分析框架下,从地方政策目标接续、产业发展行动变革、成果反馈机制构建三个方面对山西省Z县的案例资料展开分析,以期更全面地呈现基层实践中的衔接路径和基层治理样态,尝试为我国乡村振兴提供破解难题的关键路径参考。

关键词：脱贫攻坚乡村振兴目标—行动—反馈产业发展衔接路径

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Contribution and Relevance of Transfontanellar Ultrasound in Newborns in Ouagadougou: Multicentre Study on 1000 Cases

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Open Journal of Radiology 2024年第2期14卷 64-73页

作者： Ouedraogo Pakisba Ali Ouedraogo Nina-Astrid Somé Milckisédek Judickael Dabire Stive Arnauld Tankoano Ida Aida Napon Aischa madina Nikiema Zakari Diallo Ousseini Lougue Sorgho Leonie Claudine Cisse Rabiou Department of Medical Imaging Ouahigouya Regional University Hospital Centre Ouahigouya University Ouahigouya Burkina Faso Department of Diagnostic and Interventional Radiology Bogodogo University Hospital Ouagadougou Burkina Faso Department of Medical Imaging Souro Sanon University Hospital Bobo Dioulasso Burkina Faso Medical Imaging Service Yalgado Oudraogo University Hospital Ouagadougou Burkina Faso Department of Medical Imaging Charles de Gaulle Pediatric University Hospital Ouagadougou Burkina Faso Radiodiagnostic and Medical Imaging Laboratory Health Sciences Training and Research Unit Joseph Ki-Zerbo University Ouagadougou Burkina Faso

Objectives: To demonstrate the contribution and relevance of ETFs through the study of 1000 examination reports carried out in the medical imaging departments of the OUAGADOUGOU CHU. Material and method: Analytical descriptive study with retrospective collection, extended from 1st January 2020 to 1st January 2022. Results: Of the 1000 transfontanellar ultrasound reports, the mean age of patients was 7.61 +/ 7.5 days, with extremes of zero and 28 days. Sex was specified in 989 cases. Males accounted for 54.49% and females for 45.51%. 555 transfontanellar ultrasound were performed in 2020. 441 in 2021 and 4 in 2022. 61.9% of transfontanellar ultrasound were performed at the Bogodogo University Hospital, 205 at Charles de Gaulle and 176 at Tengandogo. Indications for transfontanellar ultrasound were dominated by neonatal distress (65.8%), followed by convulsions (10.2%) and prematurity (9.1%). Transfontanellar ultrasound was normal in 570 cases (57%) and abnormal in 430 cases (43%). Abnormalities were dominated by haemorrhage and ischaemic lesions in 66.28% (285) and 21.63% (93) of cases respectively. In the group of normal transfontanellar ultrasound, neonatal distress represented 59.65% of indications and prematurity 10.7% of indications. As for abnormal transfontanellar ultrasound, neonatal suffering accounted for 73.95% of indications and convulsions for 12.56%. The average age ofpatients with an abnormal transfontanellar ultrasound was 8.74 days +/ 7.89 days. The indication for investigations was relevant in 42.2% of cases and irrelevant in 57.8%;of the transfontanellar ultrasound with relevant indications, 0.71 were normal and 99.29 abnormal;of the transfontanellar ultrasound with irrelevant indications, the transfontanellar ultrasound was normal in 98.1% and abnormal in 1.9%. Conclusion: Transfontanellar ultrasound is an important part of ultrasound in current practice. Haemorrhage, anoxic-ischaemic lesions and hydrocephalus are the most frequent pathologies fou

关键词： Transfontanellar Ultrasound Neonatal Distress Relevance

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加强“新疆地方史”课程中的马克思主义民族理论政策教育教学研究

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喀什大学学报 2024年第4期45卷 108-114页

作者：杨清麦迪娜·帕它尔新疆大学马克思主义学院新疆乌鲁木齐830046

马克思主义民族理论是党的民族理论政策的指导思想,党的民族理论政策是马克思主义民族理论中国化的丰富和发展。在新疆高校,通过“新疆地方史”课程加强马克思主义民族理论政策的教育教学,有助于新疆大学生铸牢中华民族共同体意识。马... 详细信息

马克思主义民族理论是党的民族理论政策的指导思想,党的民族理论政策是马克思主义民族理论中国化的丰富和发展。在新疆高校,通过“新疆地方史”课程加强马克思主义民族理论政策的教育教学,有助于新疆大学生铸牢中华民族共同体意识。马克思主义民族理论政策是“新疆地方史”课程的理论根基,加强马克思主义民族理论政策教育教学,第一要整合教材内容,把马克思主义民族理论政策有机融入课程具体章节目中,突出马克思关于民族理论、国家理论的相关内容;第二加强实践教学,把马克思主义民族理论政策的相关内容融入实践教学环节,提升学习的重视度,把民族理论政策的重要内容纳入学生考核评价体系;第三发挥教师在教学环节的主导作用,让马克思主义民族理论专业教师参与到教、学、研、授的全过程,来增强“新疆地方史”课程中民族理论政策的教育教学针对性、指导性、有效性。

关键词： “新疆地方史”课程加强马克主义民族理论政策铸牢教育

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Eyelid Wounds: Epidemiological, Clinical and Etiological Aspects

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Open Journal of Ophthalmology 2024年第1期14卷 55-62页

作者： Aly Mbara Ka Jean Pierre Diagne Aissatou Aw El Hadji Malick Sy Soda Mbaye Hawo madina Diallo Audrey Samra Aboubacry Sadikh Sow Joseph Matar Mass Ndiaye Ousmane Ndiaga Senghor Lamine Ndiaye Mohamed Ndiaye Serigne Sohibou Gaye Papa Amadou Ndiaye Ophthalmology Department of Abass Ndao Hospital Dakar Senegal Ophthalmology Department of Aristide Le Dantec Hospital Dakar Senegal

Purpose: The aim is to show epidemiological, clinical and etiological characteristics of palpebral wounds. Methodology: This was a retrospective study focusing on patients with an eyelid wound, over a 10-year period from 2012 to 2021. We collected and analyzed the data using Excel. Results: The frequency of eyelid wounds was 0.1%. The average age of our patients was 19.38 years with a range of 1 and 62 years. The sex ratio was 3.7. Eighty-one percent of patients lived in Dakar. Fifty-seven percent (57%) of patients consulted less than 24 hours after the trauma and 7% of patients on D1. The circumstances were brawls (11%), domestic accidents (9%), road accidents (6%), and work accidents (6%). We noted 1 case of dog bite. Thirteen patients presented with post-traumatic decreased visual acuity. Involvement of the isolated upper eyelid was noted in 40% of cases and both eyelids in 15% of cases. Involvement of the lacrimal ducts was noted in 17% of cases, and that of the free edge in 21% of cases. Eyelid wounds were associated with eyeball damage in 21% of cases. Various associated lesions were observed. Ninety-one percent of patients received surgical treatment. Three cases of superinfections, 1 case of conjunctival granuloma and 1 case of phthysis of the eyeball with postoperative retinal detachment were noted. Conclusion: Eyelid sores are relatively common in our context. They require rapid surgical treatment in order to preserve the functional and aesthetic prognosis. .

关键词： Eyelid Wounds Epidemiology Clinic Etiologies

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The experience of land cover change detection by satellite data

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Frontiers of Earth Science 2012年第2期6卷 140-146页

作者： Lev SPIVAK Irina VITKOVSKAYA madina BATYRBAYEVA Alexey TEREKHOV The Institute of Space Research National Centre of Space Research and Technology of the Republic of Kazakhstan Almaty 050010 Kazakhstan

Sigificant dependence from climate and anthropogenic influences characterize ecological systems of Kazakhstan. As result of the geographical location of the republic and ecological situation vegetative degradation sites exist throughout the territory of Kazakhstan. The major process of desertification takes place in the arid and semi-arid areas. To allocate spots of stable degradation of vegetation, the transition zone was first identified. Productivity of vegetation in transfer zone is slightly dependent on climate conditions. Multi-year digital maps of vegetation index were generated with NOAA satellite images. According to the result, the territory of the republic was zoned by means of vegetation productivity criterion. All the arable lands in Kazakhstan are in the risky agriculture zone. Estimation of the productivity of agricultural lands is highly important in the context of risky agriculture, where natural factors, such as wind and water erosion, can significantly change land quality in a relatively short time period. We used an integrated vegetation index to indicate land degradation measures to assess the inter-annual features in the response of vegetation to variations in climate conditions from low- resolution satellite data for all of Kazakhstan. This analysis allowed a better understanding of the spatial and temporal variations of land degradation in the country.

关键词： remote sensing NOAA land cover changes,vegetation indexes

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