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World Journal of Cardiovascular Diseases 2023年第7期13卷 404-414页

作者： madhu Roka Keshab Raj Neupane Rabindra Simkhada Ravi Sahi Department of Medicine Gandaki Medical College Pokhara Nepal Department of Cardiology Shahid Gangalal National Heart Centre Kathmandu Nepal

Background: Dyslipidemia and hypertension are independent cardiovascular risk factors that are linked by insulin resistance and they require follow-up and more aggressive therapeutic strategies. Hence, the present study was done to study the prevalence of Diabetes and Dyslipidemia patterns in hypertensive patients. Methods: A cross-sectional observational study was done on patients with hypertension for duration of one year, i.e. from Feb 2022 to January 2023. A total of 726 hypertensive Patients were included. All calculations and statistical analyses were processed by SPSS 25.0. Results: A Total of 726 patients with a history of hypertension were included;the average age was 55, with 24.2% of patients belonging to the age group 51 - 60;55.8% were males and 44.2% were females. In the present study, the prevalence of diabetes was 29.06% and 35.5% of patients in the prediabetic stage. The most frequent dyslipidaemic form was reduced HDL, seen in 96.1% and 94% of new and old respectively;followed by elevated LDL, 86% and 48.2% in new and old respectively. It was followed by elevated TG level and Total cholesterol levels. Conclusion: There was a high prevalence of diabetes, pre-diabetes as well as dyslipidemia in hypertensive patients.

关键词： Hypertension Diabetes Dyslipidemia

Low velocity impact studies of E-glass/epoxy composite laminates at different thicknesses and temperatures

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Defence Technology（防务技术） 2019年第6期15卷 897-904页

作者： T.Sreekantha Reddy P.Rama Subba Reddy Vemuri madhu Defence Metallurgical Research Laboratory

Low velocity impact experiments were carried out on E-glass/epoxy composite laminates having varying thicknesses at sub zero and elevated temperatures using hemi spherical steel impactor of 16 mm diameter with impact energies in the rage of 50-150 *** performance of the laminates was assessed in terms of energy absorption,maximum displacement,peak force and failure *** indicated that the effect of temperature on energy absorption of the laminate is negligible although the laminates are embrittling at sub zero *** it has influence on failure behaviour and *** force has increased linearly with increase in laminate thickness from 5 to 10 *** it got reduced by 25% when temperature was increased from-20℃ to 100℃,Based on experimental results,laminate perforation energies were predicted using curve fitting *** analysis was carried out using Taguchi method to identify the global effects of various parameters on laminate performance and confirmed that the laminate thickness has significant influence as compared to temperature,for the studied range.

关键词： Laminates Glass fibres Impact behaviour Delamination

Flash X-ray radiography technique to study the high velocity impact of soft projectile on E-glass/epoxy composite material

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Defence Technology（防务技术） 2019年第2期15卷 216-226页

作者： B.Venkata Ramudu C.Jayarami Reddy V.madhu Armour Design and Development Division Defence Metallurgical Research Laboratory

In the present paper, the high velocity impact of 9 mm soft lead projectile on 10 mm and 30 mm thick Eglass/epoxy composites was studied using a 450 kV Flash X-ray radiography(FXR) system. The basic parameters of FXR imaging, such as effect of ratio of target to film(TF) and source to target(ST) distances and X-ray penetration thickness of the composite material were optimized based on clarity and the actual dimensions of the objects. The optimized parameters were used in the FXR imaging of the ballistic event of 9 mm soft projectile on E-glass/epoxy composite. The real time deformation patterns of both the projectile and composite target during the ballistic impact were captured and studied at different time intervals. The notable failure modes of the 10 mm thick target with time include fibre breakage, bulging on the back side, delamination, recovery of the bulging, reverse bulging and its recovery. However, with increase in thickness of the target to 30 mm the only failure mechanism observed is the breaking of fibres. The ballistic impact event was also numerically simulated using commercially available LS-DYNA software. The numerically simulated deformation patterns of the projectile and target at different time intervals are closely matching with the corresponding radiographic images.

关键词： Flash X-ray radiography E-Glass/epoxy composite Ballistic impact Numerical simulation

Globalization and Voluntary Environmental Management in Developing Countries

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Frontiers of Economics in China-Selected Publications from Chinese Universities 2014年第1期9卷 138-163页

作者： madhu Khanna Yuan Liao Department of Agricultural and Consumer Economics University of Illinois at Urbana-Champaign. Urbana IL 61801 USA

Weak capacity to enforce regulations and sanction violators, and an emphasis on economic growth in developing countries has led to concerns about worsening environmental conditions and the potential for these countries becoming pollution havens for multinational corporations. International environmental standards, voluntary programs, and public disclosure programs have gained popularity because they engage market participants in providing incentives for self-regulation and have the potential to substitute for the lack of domestic regulatory capacity. This paper analyzes the motivations for firms to undertake voluntary environmental management and reviews the empirical evidence on the type of firms participating in such initiatives and their effectiveness in improving environmental performance. We also consider the special case of China that has witnessed dramatic globalization following its acceptance into the World Trade Organization and participation by its firms in global supply chains. We conclude with a discussion of the effectiveness of these efforts as a substitute for weak regulatory and civic society pressures in these countries.

关键词： voluntary programs ISO 14001 public disclosure programs,foreign direct investment export-oriented firms

Mini versus ultra-mini percutaneous nephrolithotomy in a paediatric population

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Asian Journal of Urology 2022年第1期9卷 75-80页

作者： Dilip K.Mishra Sonia Bhatt Sundaram Palaniappan Talamanchi V.K.Reddy Vinothkumar Rajenthiran Y.L.Sreeranga madhu S.Agrawal Department of Urology Global Rainbow HospitalAgraUttar PradeshIndia Department of Pediatrics F H Medical CollegeAgraUttar PradeshIndia Department of Urology Sengkang General HospitalSingapore

Objective:To evaluate whether there would be a difference in outcome when the smaller ultra-mini 12 Fr sheath was used instead of the mini 16 Fr sheath for percutaneous nephrolithotomy(PCNL)in paediatric patients for stones less than 25 ***:This was a prospective cohort study of patients who underwent PCNL in our hospital in a 2-year period from July 2016 to June 2018 by a single *** was performed in a prone position and tract was dilated to the respective size using single step *** was used to fragment the ***-free outcome was defined as absence of stone fragment at 3 months on kidney,ureter,and bladder ***:There were 40 patients in each *** stone size was comparable between the two groups(14.5 mm vs.15.0 mm).The procedure was completed faster in the 16 Fr group compared to 12 Fr group(24.5 min vs.34.6 min).Stone clearance was highly successful in both groups(97.5%vs.95.0%).There was no difference in complications between the two *** decrease in hemoglobin was minimal in both groups(0.2 g/dL vs.0.3 g/dL).Conclusion:We found that the success rates were similar in both mini PCNL and the smaller ultra-mini PCNL *** significant difference in bleeding was noted in our pilot study,however,operative time was longer in the ultra-mini group as compared to the mini sheath group.

关键词： Percutaneous nephrolithotomy Mini percutaneous nephrolithotomy Ultra-mini percutaneous nephrolithotomy Minimally invasive percutaneous nephrolithotomy Paediatric percutaneous nephrolithotomy Renal stone Urolithiasis

Effect of irrigation schedule on growth and seed yield of camelina(Camelina sativa L.)in Tarai region of central Himalaya

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Oil Crop Science 2021年第1期6卷 8-11页

作者： Ankur Agarwal Om Prakash madhu Bala Defence Institute of Bio-Energy Research Defence R&D OrganizationGoraparaoP.OArjunpurHaldwaniUttarakhand263139India

Camelina(Camelina sativa)has emerged as a potential biofuel crop globally with its suitability even as a jet fuel source with 75–80%less greenhouse gas emissions compared to common petroleum *** crop has originated from Mediterranean region and belongs to Brassicaceae ***,DRDO has made initial and pioneer efforts in successful introduction of this crop to India and its agro-technology *** a short duration crop with lesser input requirement,it fits well in the cropping pattern of hilly states of Indian *** areas experience fallow land due to shortage of irrigation water for growing other *** present study revealed that irrigation at flowering stage is more *** at this stage(if only one irrigation is available)exhibited grain yield of 1.004 kg·m^(-2)which was 21 and 80%higher over pod setting and rosette stage irrigation,*** maximum seed yield was observed under treatment where irrigation was provided at all three crop growth stages(2.044 kg·m^(-2)).It was 50%higher over T6 treatment(where two irrigations were given at rosette and flowering stage)and 104%higher over T3(where only one irrigation was given at flowering stage).

关键词： Irrigation scheduling Water requirement Water deficit Biofuel crop False flax

Impact of the source and serial passaging of goat mesenchymal stem cells on osteogenic differentiation potential:implications for bone tissue engineering

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Journal of Animal Science and Biotechnology 2016年第4期7卷 482-494页

作者： Hoda Elkhenany Lisa Amelse Marc Caldwell Ramadan Abdelwahed madhu Dhar Department of Large Animal Clinical Sciences University of Tennessee Department of Surgery Faculty of Veterinary MedicineAlexandria University

Background： Adult mesenchymal stem cells （MSCs） can be conveniently sampled from bone marrow, peripheral blood, muscle, adipose and connective tissue, harvested from various species, including, rodents, dogs, cats, horses, sheep, goats and human beings. The MSCs isolated from adult tissues vary in their morphological and functional properties. These variations are further complicated when cells are expanded by passaging in culture. These differences and changes in MSCs must be considered prior to their application in the clinic or in a basic research study. Goats are commonly used as animal models for bone tissue engineering to test the potential of stem cells for bone regeneration. As a result, goat MSCs isolated from bone marrow or adipose tissue should be evaluated using in vitro assays, prior to their application in a tissue engineering project. Results： In this study, we compared the stem cell properties of MSCs isolated from goat bone marrow and adipose tissue. We used quantitative and qualitative assays with a focus on osteogenesis, including, colony forming unit, rate of cell proliferation, tri-lineage differentiation and expression profiling of key signal transduction proteins to compare MSCs from low and high passages. Primary cultures generated from each source displayed the stem cell characteristics, with variations in their osteogenic potentials. Most importantly, low passaged bone marrow MSCs displayed a significantly higher and superior osteogenic potential, and hence, will be the preferred choice for bone tissue engineering in future in vivo experiments. In the bone marrow MSCs, this process is potentially mediated by the p38 MAPK pathway. On the other hand, osteogenic differentiation in the adipose tissue MSCs may involve the p44/42 MAPK pathway. Conclusions： Based on these data, we can conclude that bone marrow and fat-derived MSCs undergo osteogenesis via two distinct signaling pathways. Even though the bone marrow MSCs are the preferred source fo

关键词： Caprine mesenchymal Osteogenesis stem cells

Numerical investigations on HCCI engine with increased induction induced swirl and engine speed

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Journal of Central South University 2015年第10期22卷 3837-3848页

作者： T.Karthikeya Sharma G.Amba Prasad Rao K.madhu Murthy Department of Mechanical Engineering NIT

Homogeneous charge compression ignition(HCCI) mode of combustion is popularly known for achieving simultaneous reduction of NOx as well as soot emissions as it combines the compression ignition(CI) and spark ignition(SI) engine features. In this work, a CI engine was simulated to work in HCCI mode and was analyzed to study the effect of induction induced swirl under varying speeds using three-zone extended coherent flame combustion model(ECFM-3Z, compression ignition) of STAR-CD. The analysis was done considering speed ranging from 800 to 1600 r/min and swirl ratios from 1 to 4. The present study reveals that ECFM-3Z model has well predicted the performance and emissions of CI engine in HCCI mode. The simulation predicts reduced in-cylinder pressures, temperatures, wall heat transfer losses, and piston work with increase in swirl ratio irrespective of engine speed. Also, simultaneous reduction in CO2 and NOx emissions is realized with higher engine speeds and swirl ratios. Low speeds and swirl ratios are favorable for low CO2 emissions. It is observed that increase in engine speed causes a marginal reduction in in-cylinder pressures and temperatures. Also, higher turbulent energy and velocity magnitude levels are obtained with increase in swirl ratio, indicating efficient combustion necessitating no modifications in combustion chamber design. The investigations reveal a total decrease of 38.68% in CO2 emissions and 12.93% in NOx emissions when the engine speed increases from 800 to 1600 r/min at swirl ratio of 4. Also an increase of 14.16% in net work done is obtained with engine speed increasing from 800 to 1600 r/min at swirl ratio of 1. The simulation indicates that there is a tradeoff observed between the emissions and piston work. It is finally concluded that the HCCI combustion can be regarded as low temperature combustion as there is significant decrease in in-cylinder temperatures and pressures at higher speeds and higher swirl ratios.

关键词： HCCI发动机发动机转速涡流比诱导数值研究均质充量压缩着火二氧化碳排放 STAR-CD

Bioactivity guided isolation of mosquito larvicide from Piper longum

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Asian Pacific Journal of Tropical Medicine 2011年第2期4卷 112-116页

作者： madhu.S Kumar Vijayan VA Shaukath AK Vector Biology Research Lab Department of Studies in ZoologyUniversity of MysoreManasagangotriMysore 570 006KarnatakaIndia Department of Studies in Zoology University of MysoreManasagangotriMysore 570 006KarnatakaIndia Department of Chemistry Yuvaraja's CollegeUniversity of MysoreMysore-05India

Objective:To isolate the larvicidal component from the fruits of Piper longum（***） against the filariasis vector,Culex quinquefasciatus（***）.Methods:Pulverized fruits of *** were subjected to soxhlet extraction using series of organic solvents of increasing *** the solvent extracts were verified for their larvicidal efficacy against 4th instar larvae of *** employing standard WHO *** fractionation through column chromatography lead to the isolation of a bioactive amide, pipyahyine from the petroleum ether ***:Petroleum ether extract was found to be the most active fraction among all the extracts tested with LC50 and LC90 being 1.03 and 2.04 ppm ***,pipyahyine,an isolated component of the same fraction was found to be even more effective than the parent extract in terms of LC50 being 0.58 and 1.88 ppm respectively. Conclusions:From the results,it is evident that *** can be considered as a powerful arsenal for the control of mosquito population.

关键词： Piper longum Bioassay Pipyahyine Culex quinquefasciatus Filariasis Larvicide

Optical properties of amorphous thin film of Se-Te-Ag system prepared by using thermal evaporation technique

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Progress in Natural Science:Materials International 2011年第1期21卷 36-39页

作者： madhu MISHRA Rashmi CHAUHAN Anju KATIYAR K.K.SRIVASTAVA Department of Physics Dayanand Braiendra Swarup D.B.S.(P.G.) CollegeKanpur(U.P.)India Department of Physics D.A-V.(P.G.) CollegeKanpur(U.P.)India Department of Physics Dayanand Brajendra Swarup D.B.S.(P.G.) CollegeKanpur(U.P.)India

Optical reflection and transmission spectra of Se80-xTe20Agx(where x=0,5,10 and 15,molar percent) chalcogenide thin films have been obtained in the range 300-1 200 nm at room *** samples are prepared by melt quenching technique and thin films are obtained by using vacuum evaporation technique on glass transition at room *** present paper reports the effect of Ag contents on various optical parameters such as optical band gap,refractive index,extinction coefficient,absorption *** spectra are used for calculating these optical *** band gap Egis determined from the plot of (ahv)1/2versus *** and imaginary parts of the dielectric constant changes slightly with the variation of Ag contents in different *** film exhibits indirect band gap which increases with increasing Ag *** observed behavior is explained on the basis of Davis and Mott model for the density of *** absorption coefficient of thin films exhibits linear dependence on photon *** optical parameters are calculated by using theory of *** the optical parameters change with the variation of the film *** spectrophotometer JASCO-UV/VIS/NIR is used to determine optical constants.

关键词： chalcogenide thin film band gap optical constant