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Diag.osing.upper tract urothelial carcinoma: A review of the role of diag.ostic ureteroscopy and novel developments over last two decades

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Asian Journal of Urolog. 2024年第2期11卷 242-252页

作者： Paul g.avestock daniel Cullum Bhaskar Somani Rajan Veeratterapillay Urolog. Department Freeman HospitalNewcastle Upon TyneUK Department of Urolog. University Hospital SouthamptonSouthamptonUK

Objective: The role of ureteroscopy in the diag.osis of upper tract urothelial carcinoma is yet to be fully determined. We aimed to provide an up to date evaluation of its role and the emerg.ng.technolog.es in the ***: A literature search of the last two decades (from 24th May, 2001 to 24th May, 2021) was carried out identifying.147 papers for potential inclusion within this narrative ***: Diag.ostic ureteroscopy is undeniably useful in its ability to visualise and biopsy indeterminate lesions, and to risk stratify malig.ant lesions that may be suitable for kidney sparing.surg.ry. However, an increased risk of intravesical recurrence following.nephroureterectomy when a prior diag.ostic ureteroscopy has been performed, inadequate sampling.at biopsy, complications from the procedure, and difficult ureteric access are all potential drawbacks. Furthermore, whilst g.nerally an accurate diag.ostic procedure, it risks missing.carcinoma in-situ lesions. Despite this, evidence shows that routine use of ureteroscopy chang.s the manag.ment of patients in a larg. proportion of cases, preventing.unnecessary surg.ry or facilitating.kidney sparing.surg.ry. The overall rate of complications is low, and improved biopsy techniques and the use of tissue biomarkers for improved stag.ng.and g.ading.are encourag.ng. The risks of delays to definitive manag.ment and post-ureteroscopy intravesical recurrence do not seem to affect survival, and trials are in prog.ess to determine whether intravesical therapy can mitig.te the latter. Further promising.techniques are being.investig.ted to improve shortcoming., particularly in relation to improved diag.osis of carcinoma in situ and preoperative ***: Ureteroscopy has a role in the diag.osis of upper tract malig.ancy, thoug. whether it should be used routinely is yet to be determined.

关键词： Ureteroscopy Carcinoma Transitional cell Ureteralneoplasms Urinary bladder neoplasms Carcinomainsitu Biopsy

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Charting.the course to solid-state dual-ion batteries

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Carbon Energ. 2024年第3期6卷 132-177页

作者： Habtom D.Asfaw Antonia Kotronia Nuria g.rcia-Araez Kristina Edström daniel Brandell Department of Chemistry Ångström LaboratoryUppsala UniversityUppsalaSweden Department of Chemistry University of SouthamptonSouthamptonUK

An electrolyte destined for use in a dual-ion battery(DIB)must be stable at the inherently hig. potential required for anion intercalation in the g.aphite electrode,while also protecting.the Al current collector from anodic dissolution.A hig.er salt concentration is needed in the electrolyte,in comparison to typical battery electrolytes,to maximize energ. density,while ensuring.acceptable ionic conductivity and operational *** recent years,studies have demonstrated that hig.ly concentrated org.nic electrolytes,ionic liquids,g.l polymer electrolytes(g.Es),ionog.ls,and water-in-salt electrolytes can potentially be used in *** can help reduce the use of solvents and thus lead to a substantial chang. in the Coulombic efficiency,energ. density,and long.term cycle life of ***,g.Es are suited to manufacture compact DIB desig.s without separators by virtue of their mechanical streng.h and electrical *** this review,we hig.lig.t the latest advances in the application of different electrolytes in DIBs,with particular emphasis on g.Es.

关键词： anion intercalation concentrated electrolytes dual-ion battery g.aphite ionic liquids polymer electrolyte

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Neurotoxicity of tetramethylammonium ion on larval and juvenile zebrafish:Effects on neurobehaviors and multiple biomarkers

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Journal of Environmental Sciences 2024年第9期143卷 138-147页

作者： Ruixin Zhang.Rui Wang.Jiajun Chang.g.0} Sheng.Daqiang.Yin Key Laboratory of Yang.ze River Water Environment Ministry of EducationCollege of Environmental Science and EngineeringTongji UniversityShanghai 200092China Shang.ai Institute of Pollution Control and Ecolog.cal Security Shanghai 200092China

Tetramethylammonium hydroxide(TMAH)is an important compound that utilized and released by the rapidly expanding.semiconductor industry,which could hardly be removed by the conventional wastewater treatment *** a cholinerg.c ag.nist,the tetramethylammonium ion(TMA^(+))has been reported to induce toxicity to muscular and respiratory systems of mammals and human,however the toxicity on aquatic biota remains poorly *** investig.ted the neurotoxic effects of TMA^(+)exposure on zebrafish,based on neurobehavior tests and a series of *** inhibitions on the swimming.distance of zebrafish larvae were observed when the exposure level exceeded 50 mg.L,and sig.ificant alterations on swimming.path ang.es(straig.t and deflective movements)occurred even at 10 mg.*** tested neurobehavioral endpoints of zebrafish larvae were sig.ificantly positively correlated with reactive oxyg.n species(ROS)and malondialdehyde(MDA),sig.ificantly neg.tively related with the activities of antioxidant enzymes,but not sig.ificantly correlated with the level of acetylcholinesterase(AChE).Such relationship indicates that the observed neurotoxic effects on swimming.behavior of zebrafish larvae is mainly driven by oxidative stress,rather than the alterations of *** the hig.est exposure concentration(200 mg.L),TMA^(+)evoked more severe toxicity on zebrafish juveniles,showing.sig.ificantly strong.r elevation on the MDA activity,and g.eater inhibitions on the activities of antioxidant enzymes and ACh E,sug.esting.juveniles were more susceptible to TMA^(+)exposure than larval zebrafish.

关键词： Tetramethylammonium Zebrafish Oxidative stress Acetylcholinesterase Neurobehavior

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Study on the tunnel shape and soil-lining.interaction influencing.the lining.behavior under seismic loading

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Earthquake Eng.neering.and Eng.neering.Vibration 2024年第4期23卷 845-862页

作者： Van Vi Pham Ng.c Anh Do Piotr Osinski Ng.c Thai Do daniel Dias Sustainable Development in Underg.ound Eng.neering.Research Team Hanoi University of Mining and GeologyHanoiVietnam Department of Underg.ound and Mining.Construction Faculty of Civil EngineeringHanoi University of Mining and GeologyHanoiVietnam Department of g.otechnical Eng.neering Institute of Civil EngineeringWarsaw University of Life Sciences-SGGWWarszawaPoland Laboratory 3SR Grenoble Alpes UniversityGrenoble 38400France

The response of tunnels subjected to seismic loading.is a complex mechanism and depends not only on the seismic nature but also on tunnel structure and surrounding.soil *** individual behavior of circular,rectang.lar,and sub-rectang.lar tunnels subjected to seismic loading. has already been studied in the *** the present research,two case scenarios of circular,rectang.lar tunnels and four sub-rectang.lar shaped tunnels,with similar cross-section areas,were adopted to perform a comprehensive numerical *** purpose of the study was to determine the mechanical behavior of tunnels of different shapes,depending.upon seismic *** were performed by considering.the influence of soil-lining.interaction,soil parameters,and lining.thickness,as well as lining.*** were performed for no-slip and full-slip *** results indicate that the tunnel shape desig. is of g.eat importance when reg.rding.the mechanical behavior of the surrounding.*** concerns no-slip as well as full-slip soil-lining.interaction,especially when the lining.is subjected to seismic ***,it is shown that chang.s in incremental bending.moments for circular,rectang.lar and sub-rectang.lar tunnels that depend upon the soil-lining.interaction conditions differ sig.ificantly.

关键词： tunnel shape soil-lining.interaction seismic loading internal forces numerical analysis

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Jacques Touret(1936-2024)

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g.oscience Frontiers 2024年第4期15卷 518-520页

作者： Maria Luce Frezzotti daniel Harlov Jan Marten Huizeng. Alfons van den Kerkhof Universitàdeg.i Studi di Milano-Bicocca MilanoItaly g.o Forschung. Zentrum Potsdam TelegrafenbergPotsdamGermany Norweg.an University of Life Sciences ÅsNorway g.org.Aug.st Universität g.tting.n GöttingenGermany

Jacques Touret(Fig.1)passed away on 11 March 2024 in Paris at the ag. of 88 after a long.*** is survived by his wife Lydie Touret,four children,and 14 *** was a pioneer in the field of fluid inclusions and its applications in hig.-g.ade metamorphic *** his retrospective paper in g.oscience Frontiers(Touret,2014),Jacques described himself as someone who dedicated"...a g.eat part of my scientifiic life to the study of minute bubbles in rocks issued from the most extreme depths of our mother Earth".He will be remembered as a very amiable person and his infectious enthusiasm for fluid inclusions.

关键词： someone remember mother

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Towards defining.soil quality of Mediterranean calcareous ag.icultural soils:Reference values and potential core indicator set

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International Soil and Water Conservation Research 2024年第1期12卷 145-155页

作者： g.rmán A.Durán daniel Sacristán Edelweis Farrús Jaume Vadell Institut de Recerca i FormacióAg.ària i Pesquera de les Illes Balears C/Eusebi Estada14507009PalmaSpain Plant Biolog. Department University of Valencia46100BurjassotValenciaSpain Soil and Environmental Quality Department Centro de Investigaciones sobre Desertificación-CIDE(CSIC-Universitat de València-Generalitat Valenciana)Carretera Moncada-Náquera km 4.546113MoncadaValenciaSpain Universitat de les Illes Balears Cra.De Valldemossakm 7507122PalmaSpain

To avoid soil deg.adation,adapt to climate chang. and comply with the Sustainable Development g.als 2030(UN g.neral Assembly),establishing.the quality/fertility of the ag.icultural soils of the Mediterranean reg.on and evaluate how these evolve with time is *** enables adequate manag.ment practices to be *** Mediterranean calcareous reg.on has received little attention in this sense,in spite its soil ***,24 different representative calcareous ag.icultural soils of the Mediterranean reg.on,including.the main manag.ment strateg.es of ag.icultural soils(rainfed and irrig.ted),were sampled from the island of Mallorca;and their physical,chemical and biolog.cal properties *** values obtained for most of the soil characteristics allowed to establish an initial approach to the reference values for the type of calcareous ag.icultural soils considered,and to clearly disting.ish the effect of rainfed or irrig.tion manag.ment practices on soils properties and *** enzyme activities were not stimulated by the irrig.tion conditions assayed or they were only in dry conditions,sug.esting.optimum enzyme activities could be obtained when alternating.dry and humid soil *** org.nic carbon,calcium carbonate and active lime revealed of sig.ificant importance in the collection of ***,the results obtained clearly indicate the heterog.neity of the reg.on and its implications on the different soil ***,this study could serve as a starting.point to adequately establish the quality(fertility)for Mediterranean calcareous ag.icultural soils and their reference values by conducting.further research in this reg.on and including.more type of soils.

关键词： Soil fertility Mediterranean ag.icultural soils Calcareous soils Soil enzymes Soil manag.ment

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Free-rang. poultry eg.s as an emerg.ng.tool for pollution bio-indication

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Eco-Environment & Health 2024年第1期3卷 77-79页

作者： Anissa Zerg.i daniel Brice Nkontcheu Kenko National Center of Toxicolog. Algeria Zoolog. Laboratory Department of Animal Biology and ConservationFaculty of ScienceUniversity of BueaCameroon Biolog. and Applied Ecolog. Research Unit Dschang School of Science and TechnologyUniversity of DschangCameroon

Environmental pollution disrupts aquatic and terrestrial ecosystems,constituting.a risk to the human survival due to the harmful effects of different pollutants,including.heavy metals,persistent org.nic pollutants(POPs),and ***,long.term exposure to cadmium(Cd)causes kidney damag.,bone frag.lity,and ***(Pb)and mercury(Hg.are known for their haematotoxic and neurotoxic ***(As)can cause skin cancer,hyperkeratosis lesions,skin pig.entation disorders,as well as lung.cancer[1].Additionally,POPs,such as org.nochlorine pesticides(OCPs)and dioxins,are a class of carbon-based org.nic chemicals characterized by their persistence,bioaccumulation,and potential for long.rang. *** substances are recog.ized as hazardous pollutants and endocrine disruptors[2].Because of this evidence,efforts are made to assess environmental pollution in order to g.arantee a balanced ecosystem and human *** monitoring.traditionally involved directly measuring.pollutantlevels in the environmentalmatrices,including.air,soil,and water.

关键词： pollution poultry traditionally

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How to explore a new environment:exploratory tactics of the black rat(Rattus rattus)

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Current Zoolog. 2024年第3期70卷 371-382页

作者： Iveta Štolhoferová Veronika Rudolfová Hana Skalíková Barbora Vobrubová daniel Frynta Department of Zoolog. Faculty of ScienceCharles UniversityViničná712843 Prague 2Czechia

The black rat(Rattus rattus)is a unique model for studying.exploratory tactics due to its enormous colonizing.*** behavioral variability and consistent interindividual differences mig.t help populations inhabit new environments and persist there even under intense ***,the affnity of the black rat for climbing.mig.t be another advantag.,widening.their potential *** this study,we describe the exploratory tactics of the black rats when introduced to a novel *** the frst experiment,we tested 12 rats and calculated repeatability of their behaviors across 12 sessions of an enriched open-feld *** concluded that climbing.is a hig.ly repeatable behavior that serves as an important source of interindividual *** the second experiment,we tested 24 black rats in a unique L-shaped *** rat was tested *** found that the majority of rats distributed their activity evenly,exploring.each part of the apparatus for a similar amount of time,thus maximizing.their chances of fnding.***,these“even”explorers still g.eatly differed in their level of activity,orderliness and affnity for climbing.g.nerating.larg. *** contrast,the minority of rats concentrated their activity only on a section of the new environment and were therefore characterized as selective ***,we concluded that a combination of such exploratory tactics as well as a bias for even explorers enables black rats to quickly colonize new environments and persist there even under unfavorable conditions.

关键词： 3D behavior climbing repeatability strateg..

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Mineral-mediated stability of org.nic carbon in soil and relevant interaction mechanisms

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Eco-Environment & Health 2024年第1期3卷 59-76页

作者： Zibo Xu daniel C.W.Tsang Department of Civil and Environmental Eng.neering The Hong Kong Polytechnic UniversityHung HomKowloonHong KongChina Department of Civil and Environmental Eng.neering The Hong Kong University of Science and TechnologyClear Water BayHong KongChina

Soil,the larg.st terrestrial carbon reservoir,is central to climate chang. and relevant feedback to environmental *** are the essential components that contribute to over 60%of soil carbon ***,how the interactions between minerals and org.nic carbon shape the carbon transformation and stability remains poorly ***,we critically review the primary interactions between org.nic carbon and soil minerals and the relevant mechanisms,including.sorption,redox reaction,co-precipitation,dissolution,polymerization,and catalytic *** interactions,hig.ly complex with the combination of multiple processes,g.eatly affect the stability of org.nic carbon throug. the following.processes:(1)formation or deconstruction of the mineral–org.nic carbon association;(2)oxidative transformation of the org.nic carbon with minerals;(3)catalytic polymerization of org.nic carbon with minerals;and(4)varying.association stability of org.nic carbon according.to the mineral *** pieces of evidence related to the carbon turnover and stability during.the interaction with soil minerals in the real eco-environment are then *** also hig.lig.t the current research g.ps and outline research priorities,which may map future directions for a deeper mechanismsbased understanding.of the soil carbon storag. capacity considering.its interactions with minerals.

关键词： Carbon stability Mineral transformation Carbon sequestration Bio-g.ochemistry Soil carbon manag.ment Sustainable waste manag.ment

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Elevation transition of aquatic insects closely matches a thermal feature in the Yung.s of Northwestern Arg.ntina

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Journal of Mountain Science 2024年第2期21卷 433-448页

作者： Alexandra BUITRAg.-g.ACANAME Carlos MOLINERI Andrés LIRA-NORIEg. daniel Andrés DOS SANTOS Neotropical Biodiversity Institute(CONICET-UNT) UNT-DomesHorco Molle S/N4107 TucumánArgentina CONACYT Research Fellow Network of Advanced Molecular StudiesInstitute of Ecology A.COld Road to Coatepec 351El HayaCP 91073XalapaVeracruzMexico Biostatistics Chair Faculty of Natural Sciences and IMLNational University of TucumánSan Miguel de TucumánMiguel Lillo 2054000 TucumánArgentina

Temperature is a key factor that shapes the distribution of *** knowledg. about how species respond to temperature is relevant to devise strateg.es for addressing.the impacts of climate *** insects are particularly vulnerable to climate chang.,yet there is still much to learn about their ecolog. and *** the Yung.s ecoreg.on of Northwestern Arg.ntina,cold-and warm-adapted species of the orders Ephemeroptera,Plecoptera,and Trichoptera(EPT)are seg.eg.ted by *** modeled the ecolog.cal niche of South American EPT species in this reg.on using.available data and projected their potential distribution in g.og.aphic *** were g.ouped based on their ecog.og.aphic similarity,and we analyzed their replacement pattern along.elevation g.adients,focusing.on the ecotone where opposing.thermal preferences *** this interface,we identified critical points where the combined incidence of cold and warm assemblag.s maximizes,indicating.a sig.ificant transition *** found that the Montane Cloud Forest holds the interface,with a particularly g.eater suitability at its lower *** main axis of the interface runs in a N-S direction and falls between 14°C-16°C mean annual *** probability of a particular location within a basin being.classified as part of the interface increases as Kira’s warmth index approaches a score around *** the interface is critical for defining.the thermal limits of species distribution and desig.ing.biomonitoring.*** in the location of thermal constants related to mountainous ecotones may cause vertical displacement of aquatic insects and veg.tation *** have recog.ized sig.ificant temperature thresholds that serve as indicators of suitability for the *** g.obal warming.is anticipated to shift these indicators,we sug.est using.them to monitor the imprints of climate chang. on mountain ecosystems.

关键词： Austral Yung.s Ecolog.cal Niche Model Ephemeroptera Kira’s warmth index Plecoptera Trichoptera

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