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Journal of Pharmaceutical Analysis 2024年第3期14卷 435-438页

作者： congyu ma Ning Sheng Jun Wu Lulu Wang Jiandong Jiang Haibo Yu Jinlan Zhang State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia MedicaChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing100050China Institute of Medicinal Biotechnology Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing100050China

Abnormal synaptic plasticity causes cognitive *** long-term potentiation(LTP)is a critical synaptic plasticity process[1].Rescuing impaired LTP is challenging;hence,novel agents are required for LTP *** medicine Dengzhan Shengmai(DzSM)has shown notable clinical efficacy against cognitive deficits[2].However,it remains unclear how DzSM modulates *** previous study[3]revealed the influence of DZSM on glutamatergic and GABAergic synapses following chronic cerebral hypoperfusion(CCH),which motivated us to assess how DzSM affects synaptic functions.

关键词： impaired impairment hence

Historical tillage promotes grass-legume mixtures establishment and accelerates soil microbial activity and organic carbon decomposition

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Journal of Arid Land 2024年第7期16卷 910-924页

作者： ZHOU Jiqiong GONG Jinchao WANG Pengsen SU Yingying LI Xuxu LI Xiangjun LIU Lin BAI Yanfu ma congyu WANG Wen HUANG Ting YAN Yanhong ZHANG Xinquan Department of Grassland Science College of Grassland Science&TechnologySichuan Agricultural UniversityChengdu 611130China Yunnan Sheep Breeding and Extension Center Kunming 655204China

Perennial grass-legume mixtures have been extensively used to restore degraded grasslands,increasing grassland productivity and forage *** is crucial for seedbed preparation and sustainable weed management for the establishment of grass-legume ***,a common concern is that intensive tillage may alter soil characteristics,leading to losses in soil organic carbon(SOC).We investigated the plant community composition,SOC,soil microbial biomass carbon(MBC),soil enzyme activities,and soil properties in long-term perennial grass-legume mixtures under two different tillage intensities(once and twice)as well as in a fenced grassland(FG).The establishment of grass-legume mixtures increased plant species diversity and plant community coverage,compared with *** with once tilled grassland(OTG),twice tilled grassland(TTG)enhanced the coverage of high-quality leguminous forage species by 380.3%.Grass-legume mixtures with historical tillage decreased SOC and dissolved organic carbon(DOC)concentrations,whereas soil MBC concentrations in OTG and TTG increased by 16.0%and 16.4%,respectively,compared with *** significantly decreased the activity of N-acetyl-β-D-glucosaminidase(NAG)by 72.3%,whereas soil enzymeβ-glucosidase(βG)in OTG and TTG increased by 55.9%and 27.3%,respectively,compared with *** analysis indicated a close association of the increase in MBC andβG activities with the rapid decline in *** result suggested that MBC was a key driving factor in soil carbon storage dynamics,potentially accelerating soil carbon cycling and facilitating biogeochemical *** establishment of grass-legume mixtures effectively improves forage quality and boosts plant diversity,thereby facilitating the restoration of degraded *** tillage assists in establishing legume-grass mixtures by controlling weeds,it accelerates microbial activity and organic carbon *** findings provide a foundation for understanding the

关键词： tillage grass-legume mixtures fencing grassland microbial biomass carbon β-glucosidase(βG) N-acetyl-β-D-glucosaminidase(NAG)

Corrigendum to“Active components of Dengzhan Shengmai ameliorate cognitive impairment by facilitating hippocampal long-term potentiation via the NMDA receptor-mediated Ca^(2+)/CaMKII pathway”[***.14(2024)435–438]

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Journal of Pharmaceutical Analysis 2024年第6期14卷 933-933页

The authors regret there was an unfortunate error in the reproduction of Fig.1I in the *** the original figure,the fluorescence picture of the positive control drug-ifenprodil was *** authors have corrected Fig.1I and provided the original fluorescence pictures of all groups(seven groups,n=5 for each group)to the editorial ***,the corrected Fig.1I is shown *** authors declare that this correction does not affect the description,interpretation,or the original conclusions of the article.

关键词： correction Active picture

超临界流体-蒸发光散射法测定常见油脂类药用辅料皂化后的脂肪酸组成及其在油脂鉴别中的应用

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色谱 2024年第6期42卷 581-589页

作者：王紫颖施海蔚马聪玉柳文媛陈蕾刘真袁耀佐张玫唐盛中国药科大学药学院江苏南京211112 江苏省食品药品监督检验研究院江苏南京210019 国家药品监督管理局化学药品杂质谱研究重点实验室江苏南京210019 中国医学科学院药物研究所北京100050 国家药典委员会北京100061 南京市食品药品监督检验院江苏南京211198 江苏科技大学环境与化学工程学院江苏镇江212003

脂肪酸是油脂类药用辅料的重要组成成分,可直接反映油脂类药用辅料及制剂的质量和安全性。本研究利用超临界流体色谱-蒸发光散射检测器,建立了同时测定肉豆蔻酸、棕榈酸、硬脂酸、花生酸、二十二烷酸和木蜡酸6种脂肪酸的分析方法。为避... 详细信息

脂肪酸是油脂类药用辅料的重要组成成分,可直接反映油脂类药用辅料及制剂的质量和安全性。本研究利用超临界流体色谱-蒸发光散射检测器,建立了同时测定肉豆蔻酸、棕榈酸、硬脂酸、花生酸、二十二烷酸和木蜡酸6种脂肪酸的分析方法。为避免脂肪酸与酯相互转化而造成的脂肪酸种类与含量测定偏差,本方法采取先皂化后测定的方式,并系统优化了实验条件,实现了6种脂肪酸的定量分析。在优化的实验条件下,6种脂肪酸可在12 min内实现高效分离,并且在各自的质量浓度范围内线性关系良好,检出限和定量限分别为5~10 mg/L和10~25 mg/L,加标回收率为80.93%~111.66%。本文所建立方法灵敏,高效,重复性和稳定性好,满足油脂类药用辅料中脂肪酸的分析要求,并成功应用于5种常见油脂类药用辅料(玉米油、大豆油、椰子油、橄榄油、花生油)中6种脂肪酸的含量测定;同时结合主成分分析方法,实现了对不同油脂类药用辅料的准确判别,为油脂类药用辅料的快速鉴别和掺伪分析提供了有价值的参考。

关键词：超临界流体色谱蒸发光散射检测器油脂类药用辅料脂肪酸皂化反应

Coherent link between a Ti:sapphire comb and a 1.5μm laser via nonlinear interaction in photonic crystal fiber

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Photonics Research 2024年第2期12卷 350-355页

作者： YUAN YAO HAOSEN SHI GUANG YANG BO LI congyu WANG HONGFU YU LONGSHENG ma YANYI JIANG State Key Laboratory of Precision Spectroscopy East China Normal UniversityShanghai 200062China Collaborative Innovation Center of Extreme Optics Shanxi UniversityTaiyuan 030006China

Optical clock networks have distinct advantages for the dissemination of time/frequency,geodesy,and fundamental *** realize such a network,the telecom band and optical atomic clocks have to be coherently *** the telecom band and optical atomic clocks reside in a distinct spectral region,second-harmonic generation is usually introduced to bridge the large frequency *** this paper,we introduce a new method to coherently link a 1550 nm continuous wave laser with a Ti:sapphire mode-locked laser-based optical frequency *** coupling the 1550 nm continuous wave laser light and the Ti:sapphire comb light together into a photonic crystal fiber,nonlinear interaction takes place,and new comblike frequency components related to the 1550 nm laser frequency are generated in the visible ***,we can detect beat notes between two combs in the visible region with a signal-to-noise ratio of more than 40 dB in a resolution bandwidth of300 *** this signal,we realize an optical frequency divider for converting the frequency of optical clocks in the visible region to the telecom band at 1.55μ*** out-of-loop measurement shows that the additional noise and uncertainty induced in optical frequency conversion are 5×10^(-18)at 1 s averaging time and 2.2×10^(-19),respectively,which are limited by the uncompensated light path fluctuation but fulfill precision measurement using state-of-the-art optical clocks.

关键词： fiber interaction nonlinear

Energy Saving Methods and Results Analysis in the Hotel

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Energy Saving Methods and Results Analysis in the Hotel

不同产地脱脂乳木果仁总酚含量测定及其生物活性

2011 2nd International Conference on Advances in Energy Engineering(ICAEE)

作者： Xinhong Zhao congyu ma Pingdao Gu Shanghai Anyo Energy Efficiency Technology Co. Ltd Enviromental Science and Engineering College in Donghua University

In this paper,the situation of energy consumptions of the hotel in the domestic was *** feasible energy-saving technologies in hotel were introduced *** energy-saving programs and the actual energy savings which were ... 详细信息

关键词： Energy consumption in hotel Energy Saving Waste heat recovery

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中国药科大学学报 2018年第5期49卷 572-579页

作者：李达马聪玉吕青林柳文媛冯锋张杰中国药科大学中药学院南京210009 江苏食品药品职业技术学院淮安223003 中国药科大学药物分析教研室南京210009 中国药科大学生物材料重点实验室南京210009

测定了26个不同产地脱脂乳木果仁甲醇提取物的总酚含量(TPC)、抗氧化、细胞毒、EB病毒早期抗原(EBV-EA)抑制等活性,并评价了TPC与各生物活性间的相关性。采用紫外分光光度法测定TPC;采用1,1-二苯基-2-苦基肼(DPPH)自由基清除法、2,2'-... 详细信息

测定了26个不同产地脱脂乳木果仁甲醇提取物的总酚含量(TPC)、抗氧化、细胞毒、EB病毒早期抗原(EBV-EA)抑制等活性,并评价了TPC与各生物活性间的相关性。采用紫外分光光度法测定TPC;采用1,1-二苯基-2-苦基肼(DPPH)自由基清除法、2,2'-连氮基-双(3-乙基苯并噻唑啉-6-磺酸)二铵盐(ABTS)自由基清除法和铁离子还原法(FRAP) 3种方法评价提取物抗氧化活性; 3-(4,5-二甲基噻唑-2)-2,5-二苯基四氮唑溴盐(MTT)法评价提取物对人白血病细胞HL60,肺癌细胞A549和乳腺癌细胞SK-BR-3的细胞毒性;间接免疫酶法评价提取物对EBV-EA抑制活性。结果表明:不同产地乳木果仁总酚含量相差较大(25. 8~265. 7 mg/g,以没食子酸计);部分产地提取物或有较好的抗氧化活性[DPPH:IC503. 4~54. 9μg/m L,ABTS:1. 11~4. 09 mmol/g(以Trolox计),FRAP:1. 24~1. 93 mmol/g(以Trolox计)]、较强的细胞毒性(对不同细胞)(IC5025. 1~95. 5μg/m L)和EBV-EA抑制活性(100μg/m L:85. 8%~94. 9%),其中TPC只与抗氧化活性有显著的相关关系(r=0. 750~0. 837,P <0. 01)。

关键词：乳木果仁总酚含量抗氧化活性细胞毒活性 EBV-EA抑制活性

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浅析空气源热泵供暖双循环的节能效果

建设科技 2022年第5期 104-106页

作者：缪兴冲王潇洋马丛雨四季沐歌科技集团有限公司北京101113

超低温空气源热泵凭借其运行的经济性、环保性,是“双碳”政策下力推的节能型高效设备。空气源热泵不同于锅炉,其供热能力受环境温度影响较大,且单台设备基本无负荷调节能力,流经热泵的最小流量与用户末端需求流量也不一致,给输送系统... 详细信息

超低温空气源热泵凭借其运行的经济性、环保性,是“双碳”政策下力推的节能型高效设备。空气源热泵不同于锅炉,其供热能力受环境温度影响较大,且单台设备基本无负荷调节能力,流经热泵的最小流量与用户末端需求流量也不一致,给输送系统选择造成较大的困扰。空气源热泵供暖循环系统有单循环与双循环两种形式,河北南宫市丽滨佳苑小区采用单循环形式,水泵耗电量超出预期145%。本文将结合河北南宫市空气源供暖项目分析两种系统形式的适应性。

关键词：单循环双循环

豆禾混播对丛枝菌根真菌群落及氮素吸收的影响

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中国草地学报 2023年第7期45卷 71-80页

作者：李香君弓晋超李旭旭马骢毓刘琳孙飞达周冀琼四川农业大学草业科技学院四川成都611130

丛枝菌根真菌是一种土壤有益真菌,能与植物形成共生关系,对植物养分吸收方面起着至关重要的作用。为了探究豆禾混播草地对AMF群落及氮养分吸收的影响,本试验在川西南建立鸭茅+白三叶+红三叶混播草地,对比混播处理与各单播对照中土壤AMF... 详细信息

丛枝菌根真菌是一种土壤有益真菌,能与植物形成共生关系,对植物养分吸收方面起着至关重要的作用。为了探究豆禾混播草地对AMF群落及氮养分吸收的影响,本试验在川西南建立鸭茅+白三叶+红三叶混播草地,对比混播处理与各单播对照中土壤AMF群落及植物氮素吸收变化机制。结果表明:1)混播中鸭茅全氮含量比鸭茅单播高57.94%,全磷含量在单播和混播中没有显著变化。混播中鸭茅δ^(15)N值显著提高,比单播鸭茅高31.04%,且鸭茅植物全氮、δ^(15)N值与菌丝密度呈正相关关系;2)混播中豆科植物固氮量比单播白三叶高103.59%、比单播红三叶高70.33%,且固氮量和菌丝密度呈显著正相关关系;3)侵染率在单播和混播中差异不显著,但混播中孢子密度及菌丝密度显著高于单播;4)混播中土壤铵态氮、微生物生物量氮显著高于单播,而单播红三叶土壤中的硝态氮含量最高。我们的试验证明了,豆禾混播草地的建植将会增加土壤中的菌丝密度和孢子密度,促进豆科植物的固氮量与禾本科植物的养分吸收。

关键词：豆禾混播 AMF ^(15)N标记养分吸收

不同豆禾混播比例对植物种间关系及草地生产力的影响

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草业科学 2022年第11期39卷 2307-2316页

作者：郭川赵艳兰李香君周冀琼刘琳孙飞达白彦福马骢毓四川农业大学草业科技学院四川成都611130

选取西南山地丘陵区常见的4种豆禾牧草鸭茅(Dactylis glomerata)、多年生黑麦草(Lolium perenne)、白三叶(Trifolium repens)、红三叶(***),设置3个豆禾比例[5:5(L_(5)G_(5))、4:6(L_(4)G_(6))、3:7(L_(3)G_(7))]及4种草单播(DG、LP、BP、TP)共7个处理。通过在3和30 cm土层进行^(15)N同位素标定,分析不同混播比例下,由不同固氮潜力及根系深度植物构建的混播及单播群落的相对总产量、竞争强度、土地当量比、超产效应、补偿效应、选择效应、植物氮磷含量、固氮量和固氮率的异同,探究混播草地的生产性能及垂直生态位养分吸收策略,揭示高产稳定混播草地的维持机制。结果表明,相较单播,4种植物混播草地具有明显的超产优势,其中L_(5)G_(5)处理的地上生物量、相对总产量、土地当量比、超产效应和植物全磷含量最高;混播草地中较高的生产力主要受到补偿效应的影响。相较单播,L_(5)G_(5)混播草地中植物在土层3 cm的^(15)N吸收量及豆科固氮量均显著提升(P<0.05),L_(5)G_(5)混播植物在浅层3 cm土壤的氮素吸收量及豆科的固氮量显著高于在深层30 cm土壤(P<0.05)。本研究为西南地区多年生混播草地生产力提升提供了理论基础及技术支撑。

关键词：豆禾混播超产效应补偿效应固氮量氮磷吸收生态位种间竞争