检索结果-南通市图书馆

Neural Regeneration Research 2023年第1期18卷 129-130页

作者： małgorzata Kujawska Ajeet Kaushik Department of Toxicology Poznan University of Medical SciencesPoznańPoland NanoBioTech Laboratory Health Systems EngineeringDepartment of Natural SciencesFlorida Polytechnic UniversityLakelandFLUSA

Towards implanted deep brain stimulation(D B S):The human brain i s a complex network of 86 billion neurons and 85 billion nonneuronal cells and they are coordinated in a well-defined ratio(1:1)which is required for desired body *** connectivity among neuronal cells secretes neurotransmitters(e.g.,dopamine)to establish a perfect connection between the brain and a peripheral system i.e.,motor coordination.

关键词： stimulation dopamine implanted

The influence of mining factors on seismic activity during longwall mining of a coal seam

在线全文

学校读者我要写书评

暂无评论

International Journal of Mining Science and Technology 2021年第3期31卷 429-437页

作者： Łukasz Wojtecki Joanna Kurzeja małgorzata Knopik Department of Geology and Geophysics Central Mining Institute40-166 KatowicePoland Polish Mining Group 40-039 KatowicePoland

In this article an attempt to determine the influence of mining factors on the seismic activity during the longwall mining of the upper layer of coal seam no.405/2 in one of the Polish hard coal mines in the Upper Silesian Coal Basin was *** longwall panels were mined in analogous geological conditions and based on the same mining system and ***,there was significant difference with regards to the mining factors,which was reflected in the observed seismic *** tools used in mining seismology were applied to illustrate the aforementioned influence of mining factors,*** frequency-energy distribution,the frequency-magnitude distribution,the 2 D distribution of released seismic energy,the relationship between released seismic energy and the volume of mined coal,the Benioff strain release,and the Gutenberg-Richter(GR)b coefficient distribution(b is the proportion between high and low energy tremors).Concerning the Benioff strain release,a new solution,based on the slope of a fitted line in a moving time window,is proposed.

关键词： Underground coal mining Induced seismicity Seismic statistics Benioff strain release

SARS-CoV-2 getting into the brain;neurological phenotype of COVID-19,and management by nano-biotechnology

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2023年第3期18卷 519-520页

作者： małgorzata Kujawska Ebrahim Mostafavi Ajeet Kaushik Department of Toxicology Poznan University of Medical SciencesPoznańPoland Stanford Cardiovascular Institute/Department of Medicine Stanford University School of MedicineStanfordCAUSA NanoBioTech Laboratory Health Systems EngineeringDepartment of Natural SciencesFlorida Polytechnic UniversityLakelandFLUSA

Human coronavirus infection getting into the brain:By February 2022,the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection,causing the coronavirus disease 2019(COVID-19)outbreak,has infected around 415 million people,and caused~5.8 million deaths worldwide(WHO,https://***/).As SARS-CoV-2 replicates during the infection,it undergoes genetic mutation to generate variants with varying characteristics and mutation *** emerging,over time,new variants that differ with transmissibility,immunity,and infection severity pose continuous challenges to established COVID-19 management strategies and *** SARS-CoV-2 variants such as Omicron(B.1.1.529),Delta(B.1.617.2),UK(B.1.17),South Africa(B.1.351),Brazil(P.1),and New York B.1.525-B.1.526 were detected worldwide and accelerated severity of COVID-19 pandemic(Figure 1A;McQuaid et al.,2021).

关键词： immunity Figure getting

Porcine Coronaviruses: Overview of the State of the Art

在线全文

学校读者我要写书评

暂无评论

Virologica Sinica 2021年第5期36卷 833-851页

作者： Hanna Turlewicz-Podbielska małgorzata Pomorska-Mo´l Department of Preclinical Sciences and Infectious Diseases Faculty of Veterinary Medicine and Animal SciencesPoznan University of Life Sciencesul.Wołyn´ska 3560-637 PoznanPoland

Like RNA viruses in general,coronaviruses(CoV)exhibit high mutation rates which,in combination with their strong tendency to recombine,enable them to overcome the host species barrier and adapt to new *** is currently known that six CoV are able to infect *** of them belong to the genus Alphacoronavirus[transmissible gastroenteritis coronavirus(TEGV),porcine respiratory coronavirus(PRCV),porcine epidemic diarrhea virus(PEDV),swine acute diarrhea syndrome coronavirus(SADS-CoV)],one of them to the genus Betacoronavirus[porcine hemagglutinating encephalomyelitis virus(PHEV)]and the last one to the genus Deltacoronavirus(PDCoV).PHEV was one of the first identified swine CoV and is still widespread,causing subclinical infections in pigs in several ***,a spike deletion mutant of TGEV associated with respiratory tract infection,appeared in the 1980 *** is considered nonpathogenic since its infection course is mild or *** its appearance,pig populations have become immune to both PRCV and TGEV,leading to a significant reduction in the clinical and economic importance of ***,PEDV and PDCoV are enteropathogenic CoV and cause clinically indistinguishable acute gastroenteritis in all age groups of *** and SADS-CoV have emerged in 2014(US)and in 2017(China),*** diagnosis is crucial for controlling CoV infections and preventing them from *** vaccines are available only for some porcine CoV,prevention should focus mainly on a high level of *** view of the diversity of CoV and the potential risk factors associated with zoonotic emergence,updating the knowledge concerning this area is essential.

关键词： Coronavirus Pig Emerging Re-emerging

Planar Blatter radicals through Bu_(3)SnH-and TMS_(3)SiH-assisted cyclization of aryl iodides: azaphilic radical addition

在线全文

学校读者我要写书评

暂无评论

Organic Chemistry Frontiers 2022年第4期9卷 929-938页

作者： paulina Bartos małgorzata Celeda Anna Pietrzak Piotr Kaszynski Faculty of Chemistry University ofŁodz91-403ŁodzPoland Faculty of Chemistry Łodz University of Technology90-924ŁodzPoland Centre of Molecular and macromolecular Studies Polish Academy of Sciences90-363ŁodzPoland Department of Chemistry Middle Tennessee State UniversityMurfreesboroTennessee 37132USA

Bu_(3)SnH-and TMS_(3)SiH-assisted cyclizations of iodoarene derivatives of benzo[e][1,2,4]triazine lead to the formation of planar Blatter radicals(2-phenyl-3H-[1,2,4]triazino[5,6,1-kl]phenoxazin-3-yls and 2-phenyl-3H... 详细信息

关键词： cyclization radicals

Neural stem cells for parkinson’s disease management:Challenges,nanobased support,and prospects

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Stem Cells 2023年第7期15卷 687-700页

作者： Tuba Oz Ajeet Kaushik małgorzata Kujawska Department of Toxicology Poznan University of Medical SciencesPoznan 60-631Poland NanoBioTech Laboratory Health System EngineeringDepartment of Environmental EngineeringFlorida Polytechnic UniversityLakelandFL 33805United States School of Engineering University of Petroleum and Energy StudiesDehradun 248007India

parkinson’s disease(PD),characterized by loss of nigrostriatal dopaminergic neurons,is one of the most predominant neurodegenerative diseases affecting the elderly population *** concept of stem cell therapy in managing neurodegenerative diseases has evolved over the years and has recently rapidly *** stem cells(NSCs)have a few key features,including selfrenewal,proliferation,and multipotency,which make them a promising agent targeting *** is generally agreed that challenges for NSC-based therapy are present at every stage of the transplantation process,including preoperative cell preparation and quality control,perioperative procedures,and postoperative graft preservation,adherence,and overall therapy *** this review,we provided a comprehensive,careful,and critical discussion of experimental and clinical data alongside the pros and cons of NSC-based therapy in *** the state-of-the-art accomplishments of stem cell therapy,gene therapy,and nanotechnology,we shed light on the perspective of complementing the advantages of each process by developing nano-stem cell therapy,which is currently a research *** various obstacles and challenges remain,nano-stem cell therapy holds promise to cure PD,however,continuous improvement and development from the stage of laboratory experiments to the clinical application are necessary.

关键词： parkinson’s disease Synuclein Neural stem cells Nanomaterials Nano-stem cell therapy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

美国的图论:第一个百年

数学译林 2024年第1期43卷 69-72页

作者： malgorzata marciniak 陆柱家(译) 童欣(校) 纽约城市大学LaGuardia社区学院不详

Robin Wilson,John ***,and David ***,Graph Theory in America:The First Hundred *** University Press,2023,320 pp.,$35.怀着极大的好奇心和夏天的热情,我把这本书拿在手里.对于精装本出版物来说,它相对较轻,非常适合在休闲度假或... 详细信息

关键词： Robin 图论 Princeton

Colovesical fistula as the initial manifestation of advanced colon cancer:A case report and review of literature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2018年第12期6卷 538-541页

作者： ma?gorzata Skierucha Wojciech Barud Jerzy Baraniak Witold Krupski Department of Internal Diseases Medical University of Lublin Department of Radiology Medical University in Lublin

Colovesical fistulas(CVFs) are rare complications of very advanced cancers of the abdominal or pelvic cavity and often cause diagnostic troubles. CVFs are found more often in males, whereas females usually suffer from rectovaginal or vesicovaginal fistulas. This article presents a case of a female patient who was admitted to the hospital because of acute diarrhea, presumably of infectious origin, and with only subtle abnormalities in blood tests and urinalysis. Owing to the ineffectiveness of the performed treatment and progressive intensification of symptoms, diagnostics were extended to include a computed tomography scan, sigmoidoscopy and cystography. The imaging results revealed a large heterogeneous conglomerate of solid and fluid structures in the pelvis, which involved reproductive organs, the bladder and sigmoid colon. The excrement leaking from the digestive tract was urine, and CVF was the fir-st manifestation of colon cancer. Shortly after the final diagnosis, the patient deteriorated and eventually died after an urgent colostomy was performed because of a bowel obstruction.

关键词： Fecaluria Pelvic cavity Colovesical fistula Colorectal cancer Diarrhea

Antibacterial and cytocompatible coatings based on poly(adipic anhydride) for a Ti alloy surface

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bioactive materials 2020年第3期5卷 709-720页

作者： Katarzyna Leśniak-Ziółkowska MonikaŚmiga-matuszowicz Agata Blacha-Grzechnik Sebastian Student Monika Brzychczy-Włoch małgorzata Krok-Borkowicz Elżbieta pamuła Wojciech Simka Alicja Kazek-Kęsik Faculty of Chemistry Silesian University of TechnologyB.Krzywoustego Street 644-100GliwicePoland Faculty of Chemistry Silesian University of TechnologyM.Strzody 9 Street44-100GliwicePoland Biotechnology Centre Silesian University of TechnologyB.Krzywoustego 8 Street44-100GliwicePoland Department of Systems Biology and Engineering Faculty of Automatic ControlElectronics and Computer ScienceSilesian University of TechnologyAkademicka 16 Street44-100GliwicePoland Department of Microbiology Jagiellonian University Medical CollegeCzysta 18 Street31-121KrakowPoland Faculty of materials Science and Ceramics AGH University of Science and TechnologyMickiewicza Av.3030-059KrakowPoland

This paper describes a formation of hybrid coatings on a Ti-2Ta-3Zr-36Nb *** is accomplished by plasma electrolytic oxidation and a dip-coating technique with poly(adipic anhydride)((C6H8O3)n)that is loaded with drugs:amoxicillin(C16H19N3O5S),cefazolin(C14H14N8O4S3)or vancomycin(C66H75Cl2N9O24·xHCl).The characteristic microstructure of the polymer was evaluated using scanning electron microscopy and confocal *** on the surface treatment,the surface roughness varied(between 1.53μm and 2.06μm),and the wettability was change with the over of time.X-ray photoelectron spectroscopy analysis showed that the oxide layer did not affect the polymer layer or loaded ***,the drugs lose their stability in a phosphate-buffered saline solution after 6.5 h of exposure,and its decrease was greater than 7%(HPLC analysis).The stability,drug release and concentration of the drug loaded into the material were precisely analyzed by high-performance liquid *** results correlated with the degradation of the polymer in which the addition of drugs caused the percent of degraded polymer to be between 35.5%and 49.4%after 1 h of material immersion,depending on the mass of the loaded drug and various biological responses that were ***,all of the coatings were cytocompatible with MG-63 osteoblast-like *** drug concentrations released from the coatings were sufficient to inhibit adhesion of reference and clinical bacterial strains(***).The coatings with amoxicillin showed the best results in the bacterial inhibition zone,whereas coatings with cefazolin inhibited adhesion of the above bacteria on the surface.

关键词： Titanium alloy poly(adipic anhydride) Antibacterial coatings Cytocompatible Dental implants