Porcine Coronaviruses: Overview of the State of the Art

作     者：Hanna Turlewicz-Podbielska Małgorzata Pomorska-Mo´l Hanna Turlewicz-Podbielska;Ma(l)gorzata Pomorska-Mól

作者机构：Department of Preclinical Sciences and Infectious DiseasesFaculty of Veterinary Medicine and Animal SciencesPoznan University of Life Sciencesul.Wołyn´ska 3560-637 PoznanPoland 

出 版 物：《Virologica Sinica》 (中国病毒学（英文版）)

年 卷 期：2021年第36卷第5期

页      面：833-851页

核心收录：

学科分类：090601[农学-基础兽医学] 09[农学] 0906[农学-兽医学] 

基　　金：supported by the National Science Centre,Poland,under research project(DEC-2014/13/B/NZ6/02566) statutory funding 506.514.05.00 of the Department of Preclinical Sciences and Infectious Diseases,Faculty of Veterinary Medicine and Animal Science,Poznan University of Life Sciences,Poznan,Poland 

主　　题：Coronavirus Pig Emerging Re-emerging 

摘      要：Like RNA viruses in general,coronaviruses(CoV)exhibit high mutation rates which,in combination with their strong tendency to recombine,enable them to overcome the host species barrier and adapt to new *** is currently known that six CoV are able to infect *** of them belong to the genus Alphacoronavirus[transmissible gastroenteritis coronavirus(TEGV),porcine respiratory coronavirus(PRCV),porcine epidemic diarrhea virus(PEDV),swine acute diarrhea syndrome coronavirus(SADS-CoV)],one of them to the genus Betacoronavirus[porcine hemagglutinating encephalomyelitis virus(PHEV)]and the last one to the genus Deltacoronavirus(PDCoV).PHEV was one of the first identified swine CoV and is still widespread,causing subclinical infections in pigs in several ***,a spike deletion mutant of TGEV associated with respiratory tract infection,appeared in the 1980 *** is considered nonpathogenic since its infection course is mild or *** its appearance,pig populations have become immune to both PRCV and TGEV,leading to a significant reduction in the clinical and economic importance of ***,PEDV and PDCoV are enteropathogenic CoV and cause clinically indistinguishable acute gastroenteritis in all age groups of *** and SADS-CoV have emerged in 2014(US)and in 2017(China),*** diagnosis is crucial for controlling CoV infections and preventing them from *** vaccines are available only for some porcine CoV,prevention should focus mainly on a high level of *** view of the diversity of CoV and the potential risk factors associated with zoonotic emergence,updating the knowledge concerning this area is essential.