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Exploring magneto-electric nanoparticles(MENPs):a platform for implanted deep brain stimulation

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Neural Regeneration Research 2023年第1期18卷 129-130页

作者： małgorzata Kujawska Ajeet Kaushik Department of Toxicology Poznan University of Medical SciencesPoznańPoland NanoBioTech Laboratory Health Systems EngineeringDepartment of Natural SciencesFlorida Polytechnic UniversityLakelandFLUSA

Towards implanted deep brain stimulation(D B S):The human brain i s a complex network of 86 billion neurons and 85 billion nonneuronal cells and they are coordinated in a well-defined ratio(1:1)which is required for desired body *** connectivity among neuronal cells secretes neurotransmitters(e.g.,dopamine)to establish a perfect connection between the brain and a peripheral system i.e.,motor coordination.

关键词： stimulation dopamine implanted

The influence of mining factors on seismic activity during longwall mining of a coal seam

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International Journal of Mining Science and Technology 2021年第3期31卷 429-437页

作者： Łukasz Wojtecki Joanna Kurzeja małgorzata Knopik Department of Geology and Geophysics Central Mining Institute40-166 KatowicePoland Polish Mining Group 40-039 KatowicePoland

In this article an attempt to determine the influence of mining factors on the seismic activity during the longwall mining of the upper layer of coal seam no.405/2 in one of the Polish hard coal mines in the Upper Silesian Coal Basin was *** longwall panels were mined in analogous geological conditions and based on the same mining system and ***,there was significant difference with regards to the mining factors,which was reflected in the observed seismic *** tools used in mining seismology were applied to illustrate the aforementioned influence of mining factors,*** frequency-energy distribution,the frequency-magnitude distribution,the 2 D distribution of released seismic energy,the relationship between released seismic energy and the volume of mined coal,the Benioff strain release,and the Gutenberg-Richter(GR)b coefficient distribution(b is the proportion between high and low energy tremors).Concerning the Benioff strain release,a new solution,based on the slope of a fitted line in a moving time window,is proposed.

关键词： Underground coal mining Induced seismicity Seismic statistics Benioff strain release

SARS-CoV-2 getting into the brain;neurological phenotype of COVID-19,and management by nano-biotechnology

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Neural Regeneration Research 2023年第3期18卷 519-520页

作者： małgorzata Kujawska Ebrahim Mostafavi Ajeet Kaushik Department of Toxicology Poznan University of Medical SciencesPoznańPoland Stanford Cardiovascular Institute/Department of Medicine Stanford University School of MedicineStanfordCAUSA NanoBioTech Laboratory Health Systems EngineeringDepartment of Natural SciencesFlorida Polytechnic UniversityLakelandFLUSA

Human coronavirus infection getting into the brain:By February 2022,the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection,causing the coronavirus disease 2019(COVID-19)outbreak,has infected around 415 million people,and caused~5.8 million deaths worldwide(WHO,https://***/).As SARS-CoV-2 replicates during the infection,it undergoes genetic mutation to generate variants with varying characteristics and mutation *** emerging,over time,new variants that differ with transmissibility,immunity,and infection severity pose continuous challenges to established COVID-19 management strategies and *** SARS-CoV-2 variants such as Omicron(B.1.1.529),Delta(B.1.617.2),UK(B.1.17),South Africa(B.1.351),Brazil(P.1),and New York B.1.525-B.1.526 were detected worldwide and accelerated severity of COVID-19 pandemic(Figure 1A;McQuaid et al.,2021).

关键词： immunity Figure getting

Porcine Coronaviruses: Overview of the State of the Art

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Virologica Sinica 2021年第5期36卷 833-851页

作者： Hanna Turlewicz-Podbielska małgorzata Pomorska-Mo´l Department of Preclinical Sciences and Infectious Diseases Faculty of Veterinary Medicine and Animal SciencesPoznan University of Life Sciencesul.Wołyn´ska 3560-637 PoznanPoland

Like RNA viruses in general,coronaviruses(CoV)exhibit high mutation rates which,in combination with their strong tendency to recombine,enable them to overcome the host species barrier and adapt to new *** is currently known that six CoV are able to infect *** of them belong to the genus Alphacoronavirus[transmissible gastroenteritis coronavirus(TEGV),porcine respiratory coronavirus(PRCV),porcine epidemic diarrhea virus(PEDV),swine acute diarrhea syndrome coronavirus(SADS-CoV)],one of them to the genus Betacoronavirus[porcine hemagglutinating encephalomyelitis virus(PHEV)]and the last one to the genus Deltacoronavirus(PDCoV).PHEV was one of the first identified swine CoV and is still widespread,causing subclinical infections in pigs in several ***,a spike deletion mutant of TGEV associated with respiratory tract infection,appeared in the 1980 *** is considered nonpathogenic since its infection course is mild or *** its appearance,pig populations have become immune to both PRCV and TGEV,leading to a significant reduction in the clinical and economic importance of ***,PEDV and PDCoV are enteropathogenic CoV and cause clinically indistinguishable acute gastroenteritis in all age groups of *** and SADS-CoV have emerged in 2014(US)and in 2017(China),*** diagnosis is crucial for controlling CoV infections and preventing them from *** vaccines are available only for some porcine CoV,prevention should focus mainly on a high level of *** view of the diversity of CoV and the potential risk factors associated with zoonotic emergence,updating the knowledge concerning this area is essential.

关键词： Coronavirus Pig Emerging Re-emerging

Planar Blatter radicals through Bu_(3)SnH-and TMS_(3)SiH-assisted cyclization of aryl iodides: azaphilic radical addition

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Organic Chemistry Frontiers 2022年第4期9卷 929-938页

作者： Paulina Bartos małgorzata Celeda Anna Pietrzak Piotr Kaszynski Faculty of Chemistry University ofŁodz91-403ŁodzPoland Faculty of Chemistry Łodz University of Technology90-924ŁodzPoland Centre of Molecular and macromolecular Studies Polish Academy of Sciences90-363ŁodzPoland Department of Chemistry Middle Tennessee State UniversityMurfreesboroTennessee 37132USA

Bu_(3)SnH-and TMS_(3)SiH-assisted cyclizations of iodoarene derivatives of benzo[e][1,2,4]triazine lead to the formation of planar Blatter radicals(2-phenyl-3H-[1,2,4]triazino[5,6,1-kl]phenoxazin-3-yls and 2-phenyl-3H... 详细信息

关键词： cyclization radicals

Neural stem cells for Parkinson’s disease management:Challenges,nanobased support,and prospects

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World Journal of Stem Cells 2023年第7期15卷 687-700页

作者： Tuba Oz Ajeet Kaushik małgorzata Kujawska Department of Toxicology Poznan University of Medical SciencesPoznan 60-631Poland NanoBioTech Laboratory Health System EngineeringDepartment of Environmental EngineeringFlorida Polytechnic UniversityLakelandFL 33805United States School of Engineering University of Petroleum and Energy StudiesDehradun 248007India

Parkinson’s disease(PD),characterized by loss of nigrostriatal dopaminergic neurons,is one of the most predominant neurodegenerative diseases affecting the elderly population *** concept of stem cell therapy in managing neurodegenerative diseases has evolved over the years and has recently rapidly *** stem cells(NSCs)have a few key features,including selfrenewal,proliferation,and multipotency,which make them a promising agent targeting *** is generally agreed that challenges for NSC-based therapy are present at every stage of the transplantation process,including preoperative cell preparation and quality control,perioperative procedures,and postoperative graft preservation,adherence,and overall therapy *** this review,we provided a comprehensive,careful,and critical discussion of experimental and clinical data alongside the pros and cons of NSC-based therapy in *** the state-of-the-art accomplishments of stem cell therapy,gene therapy,and nanotechnology,we shed light on the perspective of complementing the advantages of each process by developing nano-stem cell therapy,which is currently a research *** various obstacles and challenges remain,nano-stem cell therapy holds promise to cure PD,however,continuous improvement and development from the stage of laboratory experiments to the clinical application are necessary.

关键词： Parkinson’s disease Synuclein Neural stem cells Nanomaterials Nano-stem cell therapy

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美国的图论:第一个百年

数学译林 2024年第1期43卷 69-72页

作者： malgorzata marciniak 陆柱家(译) 童欣(校) 纽约城市大学LaGuardia社区学院不详

Robin Wilson,John ***,and David ***,Graph Theory in America:The First Hundred *** University Press,2023,320 pp.,$35.怀着极大的好奇心和夏天的热情,我把这本书拿在手里.对于精装本出版物来说,它相对较轻,非常适合在休闲度假或... 详细信息

关键词： Robin 图论 Princeton

Metals content in sediments of ephemeral streams with small reservoirs(the Negev Desert)

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International Journal of Sediment Research 2020年第3期35卷 269-277页

作者： ma?gorzata Kijowska-Struga?a ?ukasz Wiejaczka Rafa? Koz?owski Judith Lekach Polish Academy of Sciences Institute of Geography and Spatial OrganizationResearch Station in Szymbark Polish Academy of Sciences Institute of Geography and Spatial OrganizationDepartment Polish Academy of SciencesInstitute of Geography and Spatial OrganizationDepartment of Geoenvironmental Research The Jan Kochanowski University Institute of Geography and Environmental Sciences Bar-Ilan University Department of Geography and Environment

The content of 19 metals(chromium,cobalt,nickel,strontium,arsenic,magnesium,barium,cesium,gallium,rubidium,uranium,vanadium,zinc,lead,copper,cadmium,iron,manganese,and aluminum) in sediment in three ephemeral streams(Nahal Sansana,Nahal Revivim and Nahal Pura) with reservoirs in the Negev Desert is studied *** study was done in September *** samples were collected from the surface layer of sediment(up to 10 cm) in the reservoirs and in the channels upstream and downstream of the ***,which on average,accounted for 72% dominated in the *** the spatial distribution of the particle size,sand and gravel fractions were deposited in the ***,iron,and magnesium accounted for 99% of all analyzed *** Principal Component Analysis(PCA) and Hierarchical Cluster Analysis(HCA) showed that sediment in the Negev Desert channel upstream of the reservoirs had similar concentrations of *** were also found between the analyzed *** bottom sediment in reservoirs had higher concentrations of metals than sediment upstream and downstream of the *** comparison of concentrations in upstream and downstream locations did not show any unambiguous trends because metal concentrations downstream from the reservoirs were not always lower than upstream of the *** analysis of the sediment enrichment factor(EF) showed the highest value in the reservoirs and the lowest downstream of the *** concentrations of most analyzed metals did not indicate the possibility of potential ecological risk(SQG).

关键词： Metal content Sediment Reservoir Arid zone Israel

New Core-Shell Type Polymeric Supports Based on the Amberlite XAD-4 Adsorbent: A Novel Synthesis Procedure

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中国化学:英文版 2015年第5期33卷 594-600页

作者： Piotr Cyganowski Dorota Jermakowicz-Bartkowiak Jacek Chęcmanowski małgorzata Kujawska marek Bryjak Division of Polymer and Carbonacenous materials Faculty of ChemistryWroclaw University of TechnologyWybrzeze Wyspianskiego 2750-370 WroclawPoland Department of Surface Engineering Catalysis and CorrosionFaculty of ChemistryWroclaw University of TechnologyWybrzeze Wyspianskiego 2750-370 WroclawPoland

The chloromethyl groups have been introduced into commercial S/DVB copolymer matrixes via interpenetratingpolymer networks (IPN) synthesis. The procedure involves impregnation of the Amberlite XAD-4 adsorbent,with use of the vinylbenzyl chloride (VBC) and divinylbenzene (DVB) monomers mixture, and suspensionpolymerization process. The syntheses were evaluated by FT-IR spectra and SEM analyses and furthermore bychlorine content determination as well as characterization of porous structure by nitrogen adsorption at liquid nitrogentemperature. Designed synthesis approach allowed determining organic and water phases composition. Furthermore,impact of an excess of the organic phase removal method has been investigated. Basing on the obtainedresults it could be stated that the chloromethyl groups, derived from VBC monomer, were successfully introducedinto the XAD-4 structure. Captured SEM images revealed significant changes in the beads’ surface morphology afterpolymerization processes. The presented studies reveal designed and executed synthesis processes, which involvethe use of a proper water phase and excess of organic phase removal. Observed changes in the beads’ morphologysuggest that introduced functionalities are concentrated on the porous surface of the XAD-4 adsorbent.

关键词： vinylbenzyl chloride divinylbenzene mesoporous materials synthesis design interpenetrating polymer networks