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Inhibition of Ehrlich ascites carcinoma by manilkara zapota *** bark in Swiss albino mice

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Asian Pacific Journal of Tropical Biomedicine 2011年第6期1卷 448-451页

作者： m abu Osman m mamunur Rasbid m Abdul Aziz m Rowshahul Habib m Rezaul karim Department of Biochemistry and molecular Biology Faculty of ScienceRajshahi University

Objective:To evaluate the antitumor activity of manilkara zapota(***) *** bark against Ehrlich ascites carcinoma(EAC) in Swiss albino ***:The in vivo antitumour activity of the ethyl acetate extract of stem bark of *** L.(EASm) was evaluated at 50,100 and 200 mg/kg bw against EAC using mean survival *** administration of the extract of ***,viable EAC cell count and body weight in the EAC tumour hosts were *** animal was also observed for improvement in the haematological parameters(e.g.,heamoglobin content,red and white blood cells count and differential cell count) after EASm treatment. Results:Intraperitoneal administration of EASm reduced viable EAC cells,increased the survival lime,and restored altered haematological *** efficacy was observed for EASm at 100 mg/kg dose(Pm bark of *** *** significant antitumour activity.

关键词： manilkara zapota Antitumour activity Stem bark Ehrlich ascites carcinoma Haematological parameter

Rainfall prediction by using ANFIS times series technique in South Tangerang, Indonesia

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Geodesy and Geodynamics 2020年第6期11卷 411-417页

作者： Wayan Suparta Azizan abu Samah Institute of Ocean and Earth Sciences(IOES) University of Malaya50603Kuala LumpurMalaysia Department of Electrical Engineering Institut Teknologi Nasional YogyakartaJl.BabarsariCaturtunggalDepokSlemanYogyakarta55281Indonesia

Excessive rainfall is one of the triggers for the flooding phenomenon,especially in the tropics with flat or concave *** critical points in the South Tangerang region,which are currently one of the most rapidly developing cities,cannot be ignored from the flooding *** cause disturbing human activities,loss of life and property,and in turn affect the economic stretch in an *** paper aimed to predict rainfall by exploring the application of artificial intelligence techniques such as ANFIS(Adaptive Neuro Fuzzy Inference System).The proposed technique combines neural network learning abilities with transparent linguistic representations of fuzzy *** ANFIS model with various input structures and membership functions was built,trained,and tested to evaluate the capability of a *** of six-year rainfall data on a monthly basis in South Tangerang City,Banten found that rainfall prediction based on ANFIS time series is promising where 80%of data testing is well predicted.

关键词： ANFIS Time series Rainfall South Tangerang

Geochemistry, mineralogy, and radioactivity of the abu Furad Area, Central Eastern Desert, Egypt

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Acta Geochimica 2019年第2期38卷 307-326页

作者： A.m.El mezayen E.K.abu Zeid W.S.Hosny m.G.El-Feky S.m.Omar S.A.Taalab Geology Department Faculty of Science Al Azhar University Nuclear material Authority Cairo Egypt

abu Furad is in the Central Eastern Desert,Egypt. It comprises metasediments, metavolcanics,metagabbros, syn-to late-orogenic granites, and post-orogenic granites, in addition to numerous dykes and veins of different shapes and composition invading all the older rocks cropping out in the study area. Field, petrographic,mineralogical, and chemical investigations led to the classification of abu Furad granites as quartz diorite, tonalite,granodiorite, and *** oxide and trace element data revealed that the syn-to late-orogenic granites and post-orogenic granites are peraluminous. Syn-to lateorogenic granites originated from calc-alkaline volcanic arc–related magma; while the post-orogenic granites(syenogranite) are highly fractionated, calc-alkaline granite from a within plate regime. Radiometrically, the studied quartz diorite, tonalite, and granodiorite had lower uranium and thorium contents and higher eU/eTh ratios than the syenogranites. This may indicate that the syn-to late-orogenic rocks originated from sources depleted in these elements. The average e Th/eU ratio of syenogranites was higher than that of average continental crust, suggesting that the syenogranites are relatively depleted in U. The studied altered syenogranites were strongly enriched in U and Th compared to the Earth's crust. On the other hand, the average of e U in pegmatites is lower than the global average for uraniferous pegmatites. The most recorded accessory minerals in the altered syenogranites were thorite, fergusonite, samarskite, columbite, zircon, monazite, xenotime,apatite, fluorite, sphene, atacamite, and malachite, in addition to chromium and nickel inclusions.

关键词： Hydrothermal alterations major oxide and trace elements Radiometry mineralogy Geochemistry Altered syenogranites Egypt

Tritrophic interactions between parasitoids and cereal aphids are mediated by nitrogen fertilizer

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Insect Science 2015年第6期22卷 813-820页

作者： muhammad A. Aqueel abu-bakar m. Raza Rashad m. Balal muhammad A. Shahid Irfan mustafa muhammad m. Javaid simon R. Leather Division of Biology Imperial College London Silwood Park Campus Ascot SL5 7PY UK University College of Agriculture Department of Biological Sciences University of Sargodha Pakistan Department of Crop and Environment Sciences Harper Adams UniversityShropshire TFIO 8NB UK

Host plant nutritional quality can directly and indirectly affect the third trophic levels. The aphid-parasitoid relationship provides an ideal system to investigate tritrophic interactions （as the parasitoids are completely dependent for their development upon their hosts） and assess the bottom up forces operating at different concentrations of nitrogen applications. The effects of varying nitrogen fertilizer on the performance of Aphidius colemani （V.） reared on Sitobion avenae （E） and Aphidius rhopalosiphi （D.） reared on Rhopalosiphum padi （L.） were measured. Parasitism and percent emergence ofparasitoids were positively affected by nitrogen fertilizer treatments while developmental duration （egg, larval, and pupal stages） was not affected by increasing nitrogen inputs. In males and females of both parasitoid species, adult longevity increased with the increasing nitrogen fertilizer. Hind tibia length and mummy weight of both parasitoid species increased with nitrogen fertilizer concentrations, as a result of larger aphids. This study showed that nitrogen application to the soil can have important consequences for aboveground multitrophic interactions.

关键词： cereal aphid parasitoids nitrogen fertilization tritrophic interactions

mesenchymal stem cells derived secretome as an innovative cell-free therapeutic approach

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BIOCELL 2022年第4期46卷 907-911页

作者： EJLAL abu-EL-RUB RAmADA R.KHASAWNEH FATImAH A.ALmAHASNEH HANA m.ZEGALLAI Department of Basic medical Sciences Faculty of MedicineYarmouk UniversityIrbid21163Jordan Physiology and Pathophysiology Faculty of MedicineUniversity of ManitobaWinnipegR3E0W2Canada Department of Pharmacology&Therapeutics University of ManitobaWinnipegR3E0W2Canada DREAm Children’s Hospital Research Institute of ManitobaWinnipegR3E0W2Canada

The paracrine and immunomodulatory cytokines secreted by mesenchymal stem cells(mSCs),generally referred to as the mSCs derived secretome,has substantial potential for the treatment of many chronic and degenerative *** secretome contains both common and disease specific cytokines and modulators that can be beneficial against a wide range of chronic ***,we discuss the mSCs secretome composition profile and its translational applicability and the challenges surrounding its use in clinical settings.

关键词： mesencyhmal stem cells Secretome Immuno-modulation Cytokines Growth factors

Green Approach to Corrosion Inhibition of mild Steel by Lignin Sulfonate in Acidic media

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Journal of Iron and Steel Research International 2016年第7期23卷 722-732页

作者： muna A.abu-DALO Nathir A.F.AL-RAWASHDEH Ahmed A.mUTLAQ Department of Applied Chemical Sciences Jordan University of Science and Technology

The inhibition effect of lignin sulfonate against corrosion for mild steel in acidic solution has been examined by means of FTIR（fourier transform infrared spectroscopy）,FAA（flame atomic absorption）spectroscopy,SEm（scanning electron microscope）,EDS（energy dispersive X-ray spectroscopy）,and mass loss *** results revealed that lignin is a beneficial inhibitor for mild steel corrosion in acidic *** has been further found that Langmuir adsorption isotherm is obeyed by the tested lignin′s adsorption over the surface of mild *** range of inhibition efficiency（IE）in 2mol·L^（-1） HCl was found to be 75.88%-87.88%for Reax 88 A,40.72%-60.32%for Reax 88 B,and 54.32%-63.03%for Reax 100 m,after immersed at 298 Kfor 24htime.

关键词： mild steel Fourier transform infrared spectroscopy inhibition adsorption corrosion

A review of control strategies used for morphing aircraft applications

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Chinese Journal of Aeronautics 2024年第4期37卷 436-463页

作者： muhammed S.PARANCHEERIVILAKKATHIL Jafar S.PILAKKADAN Rafic m.AJAJ mohammadreza AmOOZGAR Davood ASADI Yahya ZWEIRI michael I.FRISWELL Department of Aerospace Engineering Khalifa University of Science and TechnologyAbu DhabiUnited Arab Emirates Department of Aerospace Engineering Advanced Research and Innovation Center(ARIC)Khalifa University of Science and TechnologyAbu DhabiUnited Arab Emirates Department of mechanical Materials&Manufacturing EngineeringUniversity of NottinghamNottingham NG72RDUK Department of Aerospace Engineering Adana Alparslan Turkes Science and Technology UniversityTurkey College of Engineering Swansea UniversitySwansea SA18ENUK

This paper reviews the various control algorithms and strategies used for fixed-wing morphing aircraft applications. It is evident from the literature that the development of control algorithms for morphing aircraft technologies focused on three main areas. The first area is related to precise control of the shape of morphing concepts for various flight conditions. The second area is mainly related to the flight dynamics, stability, and control aspects of morphing aircraft. The third area deals mainly with aeroelastic control using morphing concepts either for load alleviation purposes and/or to control the instability boundaries. The design of controllers for morphing aircraft/wings is very challenging due to the large changes that can occur in the structural, aerodynamic, and inertial characteristics. In addition, the type of actuation system and actuation rate/speed can have a significant effect on the design of such controllers. The aerospace community is in strong need of such a critical review especially as morphing aircraft technologies move from fundamental research at a low Technology Readiness Level(TRL) to real-life applications. This critical review aims to identify research gaps and propose future directions. In this paper, research activities/papers are categorized according to the control strategy used. This ranges from simple Proportional Integral Derivative(PID) controllers at one end to complex robust adaptive controllers and deep learning algorithms at the other end. This includes analytical, computational, and experimental studies. In addition, the various dynamic models used and their fidelities are highlighted and discussed.

关键词： Control strategies morphing aircraft Shape morphing Flight dynamics Aeroelasticity

Aqueous ruthenium detection by microwave-assisted laser-induced breakdown spectroscopy

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Plasma Science and Technology 2022年第8期24卷 32-39页

作者： abu Farhan abu KASIm m A WAKIL Kevin GRANT milton HEARN Zeyad T ALWAHABI School of Chemical Engineering The University of AdelaideAdelaide SA 5005Australia

Aqueous ruthenium was detected in real-time under ambient conditions using microwaveassisted laser-induced breakdown spectroscopy(mW-LIBS).A 10 mJ laser energy and 750 W microwave power were directed at an open liquid jet sample of *** was observed that,for liquid flow,the coupling efficiency between the microwave and the laser-induced plasma was limited to 43%.The improvement in the ruthenium’s signal-to-noise ratio with mW-LIBS,with respect to LIBS,was *** on mW-LIBS,the limit of detection for aqueous ruthenium was determined to be 957±84 ppb.

关键词： microwave-assisted laser induced breakdown spectroscopy ruthenium detection laser induced breakdown spectroscopy

CDYL1 fosters double-strand break-induced transcription silencing and promotes homology-directed repair

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Journal of molecular Cell Biology 2018年第4期10卷 341-357页

作者： Enas R. abu-Zhayia Samah W. Awwad Bella m. Ben-Oz Hanan Khoury-Haddad Nabieh Ayoub Department of Biology Technion-Israel Institute of Technology Haifa 3200003 Israel

Cells have evolved DNA damage response （DDR） to repair DNA lesions and thus preserving genomic stability and impeding carcinogenesis. DNA damage induction is accompanied by transient transcription repression. Here, we describe a previously unrecognized role of chromodomain Y-like （CDYL1） protein in fortifying double-strand break （DSB）-induced transcription repression and repair. We showed that CDYL1 is rapidly recruited to damaged euchromatic regions in a poly （ADP-ribose） polymerase 1 （PARP1）-dependent, but ataxia telangiectasia mutated （ATm）-independent, manner. While the C-terminal region, containing the enoyl-CoA hydratase like （ECH） domain, of CDYL1 binds to poly （ADP-ribose）（PAR） moieties and mediates CDYL1 accumulation at DNA damage sites, the chromodomain and histone H3 trimethylated on lysine 9 （H3K9me3） mark are dispensable for its recruitment. Furthermore, CDYL1 promotes the recruitment of enhancer of zeste homolog 2 （EZH2）, stimulates local increase of the repressive methyl mark H3K27me3, and promotes transcription silencing at DSB sites. In addition, following DNA damage induction, CDYL1 depletion causes persistent G2/m arrest and alters H2AX and replication protein A （RPA2） phosphorylation. Remarkably, the ‘traffic-light reporter’ system revealed that CDYL1 mainly promotes homology-directed repair （HDR） of DSBs in vivo. Consequently, CDYL1-knockout cells display synthetic lethality with the chemotherapeutic agent, cisplatin. Altogether, our findings identify CDYL1 as a new component of the DDR and suggest that the HDR-defective ‘BRCAness’ phenotype of CDYL1-deficient cells could be exploited for eradicating cancer cells harboring CDYL1 mutations.

关键词： CDYL1 PARP1 double-strand breaks homology-directed repair non-homologous end joining H3K27me3 EZH2