Mesenchymal stem cells derived secretome as an innovative cell-free therapeutic approach

作     者：EJLAL ABU-EL-RUB RAMADA R.KHASAWNEH FATIMAH A.ALMAHASNEH HANA M.ZEGALLAI 

作者机构：Department of Basic Medical SciencesFaculty of MedicineYarmouk UniversityIrbid21163Jordan Physiology and PathophysiologyFaculty of MedicineUniversity of ManitobaWinnipegR3E0W2Canada Department of Pharmacology&TherapeuticsUniversity of ManitobaWinnipegR3E0W2Canada DREAMChildren’s Hospital Research Institute of ManitobaWinnipegR3E0W2Canada 

出 版 物：《BIOCELL》 (生物细胞（英文）)

年 卷 期：2022年第46卷第4期

页      面：907-911页

核心收录：

学科分类：1001[医学-基础医学(可授医学、理学学位)] 100101[医学-人体解剖与组织胚胎学] 10[医学] 

主　　题：Mesencyhmal stem cells Secretome Immuno-modulation Cytokines Growth factors 

摘      要：The paracrine and immunomodulatory cytokines secreted by mesenchymal stem cells(MSCs),generally referred to as the MSCs derived secretome,has substantial potential for the treatment of many chronic and degenerative *** secretome contains both common and disease specific cytokines and modulators that can be beneficial against a wide range of chronic ***,we discuss the MSCs secretome composition profile and its translational applicability and the challenges surrounding its use in clinical settings.