检索结果-南通市图书馆

采用开放式1.0TmRI行mR引导下椎小关节注射疗法的预后研究

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

国际医学放射学杂志 2014年第1期 95-96页

作者： P.Freyhardt T.Hartwig m.D.Bucourt m.maurer D.Renz B.Gebauer 谷磊磊 Charité Universitátsmedizin Berlin Department of Radiology Augustenburger Platz 113353 Berlin Germany

目的评估使用1.0 T开放式mR设备行mR引导下椎小关节注射治疗的准确性、安全性及其疗效。方法采用质子加权毁损自旋回波序列,对45例下腰痛病人在mR透

关键词：开放式磁共振磁共振介入关节内注射治疗下腰痛临床预后

三维C臂CT引导下经颈静脉肝内门体分流术的可行性、技术成功率及操作时间

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

国际医学放射学杂志 2017年第1期 109-110页

作者： D.Ketelsen G.Groezinger m.maurer U.m.Lauer U.Grosse m.Horger 黄黎香 Department of Diagnostic and Interventional Radiology University of Tuebingen

摘要目的经颈静脉肝内门体静脉分流术成为治疗门静脉高压症的标准疗法。其中最有难度的一个步骤是门静脉的盲穿。本研究的目的是评估门静脉分支及门静脉靶向穿刺

关键词：经颈静脉门体静脉分流术门静脉颈静脉门脉系统成功率肝内门体静脉分流术操作时间 CT

ligelizumab治疗成人和青少年慢性自发性荨麻疹患者的临床研究

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

中国临床药理学杂志 2024年第3期40卷 453-453页

作者： maurer m 戴荣源

德国柏林夏里特医学院maurer团队报告了2项ligelizumab的3期临床研究结果。PEARL-1和PEARL-2是相同设计的随机、双盲、活性对照和安慰剂对照平行组研究。从46个国家的347个研究点招募了≥12岁的中重度H1-AH难治性慢性自发性荨麻疹(chron... 详细信息

德国柏林夏里特医学院maurer团队报告了2项ligelizumab的3期临床研究结果。PEARL-1和PEARL-2是相同设计的随机、双盲、活性对照和安慰剂对照平行组研究。从46个国家的347个研究点招募了≥12岁的中重度H1-AH难治性慢性自发性荨麻疹(chronic spontaneous urticaria,CSU)患者,并通过交互反应技术以3∶3∶3∶1的比例随机分配给予ligelizumab 72、120 mg,omalizumab 300 mg或安慰剂,每4周给药1次,持续52周。分配给安慰剂的患者从第24周开始接受ligelizumab 120 mg治疗。主要终点是第12周每周荨麻疹活动评分(urticaria activity score,UAS7)与基线的变化(change-from-baseline,CFB)。

关键词：临床研究结果慢性自发性荨麻疹安慰剂对照交互反应随机分配

Cutaneous manifestations of HIV/AIDS in the Era of Highly Active Antiretroviral Therapy: Evidence from Bangladesh

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Dermatology and Venereology 2022年第1期5卷 8-14页

作者： mohammad Rafiqul mowla mohammed Abul manchur A Q m Serajul Islam Toby maurer Department of Dermatology and Venereology Chittagong Medical CollegeChittagong 4203Bangladesh Department of microbiology University of ChittagongChittagong 4331Bangladesh Department of Dermatology Indiana UniversityBloomingtonIN 47405USA Institute for Global Health University of CaliforniaSan FranciscoCA 94110USA

Objective:Skin diseases are common and striking features of patients with human immunodeficiency virus/acquired immunodeficiency syndrome(HIV/AIDS)and may vary considerably by ethnic and geographic regions and by the influence of highly active antiretroviral therapy(HAART).However,little information exists regarding the cutaneous manifestations of patients with HIV/AIDS in *** study was performed to elucidate the spectrum of cutaneous disorders in patients with HIV/AIDS in the era of ***:This descriptive cross-sectional study was carried out in Chittagong medical College Hospital,Bangladesh from January 2017 and December *** case of HIV/AIDS for HAART therapy and all cases of HIV/AIDS who are already on HAART therapy were included in this *** statistical analysis was carried out by using frequencies and ***:Of 40 patients with HIV/AIDS,22(55.0%)were male and 18(45.0%)were *** patients ranged in age from 8 to 60 years,with a mean age of 38±0.966 *** all age groups,the highest 19(47.5%)patients were in the 31-to 40-year age *** of the patients were migrant workers[22/40(55.0%)]with low socioeconomic status[32/40(80.0%)],and the most common transmission mode was heterosexual activity[36/40(90.0%)].most of the patients[32/40(80.0%)]had mucocutaneous disorders,30/40(75.0%)had infective dermatoses,and 21/40(52.5%)had non-infective inflammatory *** of forty(20.0%)patients presented with three or more skin *** most common infective dermatoses were fungal infections[15/40(37.5%)],followed by viral infections[8/40(20.0%)],bacterial infections[4/40(10.0%)],and scabies[3/40(7.5%)].The most common non-infective dermatosis was generalized pruritus[6/40(15.0%)],followed by prurigo simplex[4/40(10.0%)],psoriasis[4/40(10.0%)],eczema[3/40(7.5%)],pruritic papular eruption[1/40(2.5%)],seborrheic dermatitis[1/40(2.5%)],urticaria[1/40(2.5%)],and xerosis[1/40(2.5%)].Patients treat

关键词： Bangladesh Chittagong cutaneous highly active antiretroviral therapy(HAART) human immunodefi-ciency virus/acquired immunodeficiency syndrome(HIV/AIDS)

Radiofrequency ablation of liver tumors: Actual limitations and potential solutions in the future

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Hepatology 2011年第1期3卷 8-14页

作者： Beat m Künzli Paolo Abitabile Christoph A maurer Department of Surgery Kantonsspital Liestal

Over the past decade,radiofrequency ablation(RFA) has evolved into an important therapeutical tool for the treatment of non resectable primary and secondary liver *** clinical benefit of RFA is represented in several clinical *** underline the safety and feasibility of this new and modern concept in treating liver *** has proven its clinical impact not only in hepatocellular carcinoma(HCC) but also in metastatic disease such as colorectal cancer(CRC).Due to the increasing number of HCC and CRC,RFA might play an even more important role in the ***,the refinement of RFA technology is as important as the evaluation of data of prospective randomized trials that will help define guidelines for good clinical practice in RFA application in the *** combination of hepatic resection and RFA extends the feasibility of open surgical procedures in patients with extensive *** effects of RFA such as biliary tract damage,liver failure and local recurrence remain an important task today but overall the long term results of RFA application in treating liver tumors are *** ablation of liver tumors due to insufficient technology of ablation needles,tissue cooling by the neighbouring blood vessels,large tumor masses and ablation of tumors in close vicinity to heat sensitive organs remain difficult tasks for *** solutions to overcome these limitations of RFA will include refinement of ultrasonographic guidance(accuracy of probe placement),improvements in needle technology(*** preventing charring)and intraductal cooling techniques.

关键词： Radiofrequency ablation Hepatocellular carcinoma Thermoablation Colorectal cancer Liver metastases

Composite tissue allotransplantation: opportunities and challenges

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cellular & molecular Immunology 2019年第4期16卷 343-349页

作者： Jasper Iske Yeqi Nian Ryoichi maenosono max maurer Igor m.Sauer Stefan G.Tullius Division of Transplant Surgery Department of SurgeryBrigham and Women’s HospitalHarvard Medical SchoolBostonMAUSA Institute of Transplant Immunology Integrated Research and Treatment Center TransplantationHannover Medical SchoolHannoverLower SaxonyGermany Department of Surgery Charité-Universitätsmedizin BerlinCampus CharitéMitte and Virchow-KlinikumBerlinGermany Einstein-BIH Visiting Fellow Department of SurgeryCharité-Universitätsmedizin BerlinCampus CharitéMitte and Virchow-KlinikumcBerlinGermany

Vascularized composite allotransplants(VCAs)have unique properties because of diverse tissue components transplanted en mass as a single *** addition to surgery,this type of transplant also faces enormous immunological challenges that demand a detailed analysis of all aspects of alloimmune responses,organ preservation,and injury,as well as the immunogenicity of various tissues within the VCA grafts to further improve graft and patient ***,the side effects of long-term immunosuppression for VCA patients need to be carefully balanced with the potential benefit of a non-life-saving *** this review article,we provide a comprehensive update on limb and face transplantation,with a specific emphasis on the alloimmune responses to VCA,established and novel immunosuppressive treatments,and patient outcomes.

关键词： surgery challenges graft

Performance and calibration of quark/gluon-jet taggers using 140 fb^(-1) of pp collisions at √s=13 TeV with the ATLAS detector

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics C 2024年第2期48卷 1-25页

作者： G. Aad B. Abbott K. Abeling N.J. Abicht S.H. Abidi A. Aboulhorma H. Abramowicz H. Abreu Y. Abulaiti B.S. Acharya C. Adam Bourdarios L. Adamczyk S.V. Addepalli m.J. Addison J. Adelman A. Adiguzel T. Adye A.A. Affolder Y. Afik m.N. Agaras J. Agarwala A. Aggarwal C. Agheorghiesei A. Ahmad F. Ahmadov W.S. Ahmed S. Ahuja X. Ai G. Aielli A. Aikot m. Ait Tamlihat B. Aitbenchikh I. Aizenberg m. Akbiyik T.P.A. Åkesson A.V. Akimov D. Akiyama N.N. Akolkar K. Al Khoury G.L. Alberghi J. Albert P. Albicocco G.L. Albouy S. Alderweireldt m. Aleksa I.N. Aleksandrov C. Alexa T. Alexopoulos F. Alfonsi m. Algren m. Alhroob B. Ali H.m.J. Ali S. Ali S.W. Alibocus m. Aliev G. Alimonti W. Alkakhi C. Allaire B.m.m. Allbrooke J.F. Allen C.A. Allendes Flores P.P. Allport A. Aloisio F. Alonso C. Alpigiani m. Alvarez Estevez A. Alvarez Fernandez m. Alves Cardoso m.G. Alviggi m. Aly Y. Amaral Coutinho A. Ambler C. Amelung m. Amerl C.G. Ames D. Amidei S.P. Amor Dos Santos K.R. Amos V. Ananiev C. Anastopoulos T. Andeen J.K. Anders S.Y. Andrean A. Andreazza S. Angelidakis A. Angerami A.V. Anisenkov A. Annovi C. Antel m.T. Anthony E. Antipov m. Antonelli F. Anulli m. Aoki T. Aoki J.A. Aparisi Pozo m.A. Aparo L. Aperio Bella C. Appelt A. Apyan N. Aranzabal S.J. Arbiol Val C. Arcangeletti A.T.H. Arce E. Arena J-F. Arguin S. Argyropoulos J.-H. Arling O. Arnaez H. Arnold G. Artoni H. Asada K. Asai S. Asai N.A. Asbah J. Assahsah K. Assamagan R. Astalos S. Atashi R.J. Atkin m. Atkinson H. Atmani P.A. Atmasiddha K. Augsten S. Auricchio A.D. Auriol V.A. Austrup G. Avolio K. Axiotis G. Azuelos D. Babal H. Bachacou K. Bachas A. Bachiu F. Backman A. Badea P. Bagnaia m. Bahmani A.J. Bailey V.R. Bailey J.T. Baines L. Baines O.K. Baker E. Bakos D. Bakshi Gupta V. Balakrishnan R. Balasubramanian E.m. Baldin P. Balek E. Ballabene F. Balli L.m. Baltes W.K. Balunas J. Balz E. Banas m. Bandieramonte A. Bandyopadhyay S. Bansal L. Barak m. Barakat E.L. Barberio D. Barberis m. Barbero m.Z. Barel K.N. Barends T. Barillari m-S. Barisits T. Barklow P. Baron D.A. Baron mo The ATLAS Collaboration

The identification of jets originating from quarks and gluons,often referred to as quark/gluon tagging,plays an important role in various analyses performed at the Large Hadron Collider,as Standard model measurements and searches for new particles decaying to quarks often rely on suppressing a large gluon-induced *** paper describes the measurement of the efficiencies of quark/gluon taggers developed within the ATLAS Collaboration,using √s=13 TeV proton–proton collision data with an integrated luminosity of 140 fb^(-1) collected by the ATLAS *** taggers with high performances in rejecting jets from gluon over jets from quarks are studied:one tagger is based on requirements on the number of inner-detector tracks associated with the jet,and the other combines several jet substructure observables using a boosted decision tree.A method is established to determine the quark/gluon fraction in data,by using quark/gluon-enriched subsamples defined by the jet *** in tagging efficiency between data and simulation are provided for jets with transverse momentum between 500 GeV and 2 TeV and for multiple tagger working points.

关键词： ATLAS JET QUARK GLUON TAGGING

Cytoreductive radical prostatectomy after chemohormonal therapy in patients with primary metastatic prostate cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Urology 2022年第1期9卷 69-74页

作者： Christa Babst Thomas Amiel Tobias maurer Sophie Knipper Lukas Lunger Robert Tauber margitta Retz Kathleen Herkommer matthias Eiber Gunhild von Amsbergb markus Graefen Juergen Gschwend Thomas Steuber matthias Heck Department of Urology Technical University of MunichRechts der Isar Medical CenterMunichGermany martini-Klinik Prostate Cancer Center HamburgGermany

Objective:Cytoreductive radical prostatectomy(cRP)has been proposed as local treatment option in metastatic hormone-sensitive prostate cancer(mHSPC)to prevent local complications and potentially improve oncological *** this study,we examined the feasibility of a multimodal concept with primary chemohormonal therapy followed by cRP and analyzed prostate size reduction under systemic treatment,postoperative complication rates,as well as early postoperative ***:In this retrospective study,38 patients with mHSPC underwent cRP after primary chemohormonal therapy(3-monthly luteinising hormone-releasing hormone-analogue+six cycles 3-weekly docetaxel 75 mg/m2)at two centers between September 2015 and December ***:Overall,10(26%)patients had high volume and 28(74%)patients had low volume disease at diagnosis,according to CHAARTED *** prostate-specific antigen(PSA)decreased from 65 ng/mL(interquartile range[IQR]35.0-124.5 ng/mL)pre-chemotherapy to 1 ng/mL(IQR 0.3-1.7 ng/mL)*** gland volume was significantly reduced by a median of 50%(IQR 29%-56%)under chemohormonal therapy(p=0.003).Postoperative histopathology showed seminal vesicle invasion in 33(87%)patients and negative surgical margins in 17(45%)*** complications(Grade 3 according to Clavien-Dindo)were observed in 4(11%)patients within 30 *** was reached in 87%of patients after 1 month and in 92%of patients after 6 *** time to castration-resistance from begin of chemohormonal therapy was 41.1 months and from cRP was 35.9 *** PSA-nadir≤1 ng/mL versus>1 ng/mL was a significant predictor of time to castration-resistance after cRP(median not reached versus 5.3 months;pme under chemohormonal therapy going along with a low postoperative complication and high early continence ***,the oncologic benefit from cRP is still under evaluation.

关键词： metastatic hormone-sensitive prostate cancer Chemohormonal therapy Cytoreductive radical prostatectomy Feasibility Prevent local complications Continence rate

Organosilane surfactant-assisted synthesis of mesoporous SSZ-39 zeolite with enhanced catalytic performance in the methanol-to-olefins reaction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Chemical Science and Engineering 2020年第2期14卷 267-274页

作者： Hao Xu Chi Lei Qinming Wu Qiuyan Zhu Xiangju meng Daniel Dai Stefan maurer Andrei-Nicolae Parvulescu Ulrich muller Fengshou Xiao Key Laboratory of Applied Chemistry of Zhejiang Province Department of ChemistryZhejiang UniversityHangzhou 310028China BASF Catalysts(Shanghai)Co. Ltd.Shanghai 201206China BASF SE Ludwigshafen 67056Germany

SSZ-39 zeolite with AEI framework structure is a good catalyst candidate for the methanol-to-olefins(mTO)***,the diffusion limitation and coke formation often results in fast deactivation of the SSZ-39 zeolite *** solution for this challenge is to introduce mesoporosity in the SSZ-39 ***,we report the synthesis of mesoporous SSZ-39 zeolite using an organosilane surfactant,,-dimethyl--(3-(trimethoxysilyl)propyl)octan-1-aminium chloride,as a mesopore template and,-dimethyl--2,6-dimethylpiperidinium as a micropore *** obtained zeolites were characterized by X-ray diffraction,N sorption,scanning electron microscopy,temperature programmed desorption of ammonia,and magic angle spinning nuclear magnetic resonance of *** results show that the mesoporous SSZ-39 zeolite has high crystallinity,meso/microporosity,high surface area,cuboid morphology,and abundant acidic *** importantly,this mesoporous SSZ-39 zeolite exhibits enhanced catalyst lifetime in the mTO reaction due to the presence of mesoporosity for fast mass transfer,compared with a conventional SSZ-39 zeolite without mesoporosity.

关键词： SSZ-39 zeolite mesopores organosilane surfactant mTO reaction soft template mass transfer