Radiofrequency ablation of liver tumors: Actual limitations and potential solutions in the future
Radiofrequency ablation of liver tumors: Actual limitations and potential solutions in the future作者机构：Department of SurgeryKantonsspital Liestal
出 版 物：《World Journal of Hepatology》 (世界肝病学杂志（英文版）（电子版）)
年 卷 期：2011年第3卷第1期
页 面：8-14页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Radiofrequency ablation Hepatocellular carcinoma Thermoablation Colorectal cancer Liver metastases
摘 要：Over the past decade,radiofrequency ablation(RFA) has evolved into an important therapeutical tool for the treatment of non resectable primary and secondary liver *** clinical benefit of RFA is represented in several clinical *** underline the safety and feasibility of this new and modern concept in treating liver *** has proven its clinical impact not only in hepatocellular carcinoma(HCC) but also in metastatic disease such as colorectal cancer(CRC).Due to the increasing number of HCC and CRC,RFA might play an even more important role in the ***,the refinement of RFA technology is as important as the evaluation of data of prospective randomized trials that will help define guidelines for good clinical practice in RFA application in the *** combination of hepatic resection and RFA extends the feasibility of open surgical procedures in patients with extensive *** effects of RFA such as biliary tract damage,liver failure and local recurrence remain an important task today but overall the long term results of RFA application in treating liver tumors are *** ablation of liver tumors due to insufficient technology of ablation needles,tissue cooling by the neighbouring blood vessels,large tumor masses and ablation of tumors in close vicinity to heat sensitive organs remain difficult tasks for *** solutions to overcome these limitations of RFA will include refinement of ultrasonographic guidance(accuracy of probe placement),improvements in needle technology(*** preventing charring)and intraductal cooling techniques.
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