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mRI与68Ga-PSmA-11 PET/mRI的PSmA-PET联合评估前列腺癌复发

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国际医学放射学杂志 2024年第5期 623-623页

作者： K.Jannusch N.m.Bruckmann J.morawitz m.Boschheidgen H.H.quick K.Herrmann 张昕怡苗彦

目的探讨mRI与68Ga-PSmA-11 PET/mRI的PET评估前列腺癌（PCa）生化复发分期的优势。方法本回顾性研究纳入PCa生化复发并进行全身增强68Ga-PSmA-11

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Efficacy of 1% Permethrin and 2% Permethrin Combined with 1% Piperonyl Butoxide against Rhipicephalus sanguineus Ticks in Naturally Infested Dogs

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Pharmacology & Pharmacy 2024年第7期15卷 237-247页

作者： Andrea márquez-Aguado Froylán Ibarra-Velarde Joaquín Ambia-medina Rosa Arias-García Departamento de Parasitologa Facultad de Medicina Veterinaria y Zootecnia Universidad Nacional Autnoma de Mxico Mexico City Mxico Laboratorios Salud Animal S.A de C.V. Mexico City Mxico

The aim of the present study was to compare the ixodicide efficacy of 1% permethrin applied as a shampoo-bath in single treatment and a combined formulation of 2% permethrin + 1% piperonyl butoxide applied as powder in a single treatment against Rhipicephalus sanguineus ticks, in naturally infested dogs. Eighteen adult cross-mixed dogs, harboring to at least 20 ticks/animal, were selected on pre-treatment live tick counts. On day 0, the dogs were then divided in 3 groups of 6 animals each, for treatment: Group 1 (G1) received 1% permethrin applied as shampoo-bath (approximately 10 ml/kg bw), according to label instructions. G2 was treated with 2% permethrin + 1% piperonyl butoxide applied as powder, and rubbed as massage on the body, as recommended by the producer. G3 served as a non-treated control. After the treatment, the dogs were checked out for live ticks counting on days 0, 1, 7, and 14. The ixodicide efficacy was assessed based on the percentage reductions of ticks on the days analyzed post-treatment, with respect to the untreated control. Results showed that permethrin alone removed ticks on 81%, 93.1% and 89.6% for days 1, 7 and 14, respectively. The combined formulation of 2% permethrin + 1% piperonyl butoxide exerted a better efficacy of 98.8, 97.7 and 97.0%, respectively. It is concluded that this combined formulation was highly effective at rapidly repelling and killing Riphicephalus sanguineus ticks on naturally infected dogs, showing a significant effect on days 1, 7 and 14 after tick exposure. The sustained high and quick level of efficacy of this combination may well interfere with the transmission of Riphicephalus sanguineus ticks. It is concluded that the sustained high level of efficacy of the permethrin + piperonyl butoxide combination may well exert an additive effect and could interfere with the transmission of Riphicephalus sanguineus ticks.

关键词： Efficacy Permethrin Permethrin + Piperonyl Butoxide Riphicephalus sanguineus Dogs

Effect of Turbidity on Semi-Automatic Analysis of Copepod Size and Abundance Distribution in the Water Column

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Advances in Bioscience and Biotechnology 2024年第6期15卷 380-395页

作者： Thiago da Silva matos Carolina Siqueira dos Reis Laura de Andrade moura márcio Abreu Ricardo Coutinho Lohengrin Fernandes IEAPm/UFF marine Biotechnology Post-Graduate Program Arraial do Cabo Brazil Instituto de Estudos do mar Almirante Paulo moreira Arraial do Cabo Brazil

Automated image systems to characterize aquatic organisms improve research and enable fast response to environmental risk situations. In November 2015, a dam in mariana City-mG (Brazil) collapsed and led to the disposal of mud tailings from the mining process to the Doce River. The accident resulted in several casualties and incalculable damage to surrounding communities and the environment. The mud increased water turbidity, an essential condition to the functioning of the image analysis systems, and directly affected the characterization of the organisms, making it impossible to distinguish copepods in the mud, due to the blurred outline. To get a quick response evaluating environmental situations, this work aimed to develop and test different algorithms characterizing and classifying copepods by their size (length and area) using in situ images acquired by the Lightframe On-Sight Keyspecies Investigation device. Field tests were carried out under different turbidity levels throughout the gradient observed in the coastal zone adjacent to the Doce River. The best algorithm reduced nearly 50% of the noise in some images when compared with manual treatment and led to 96% accuracy in measurement and counting. Semi-automated devices that perform post-processing corrections are suitable for fast environmental evaluation under high turbidity scenarios.

关键词： Imaging Zooplankton Doce River LOKI Copepod

C.V.m.史密斯:《生命问题》——一本关于生物学思想来源的论著

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世界科学 1981年第9期 59-60页

作者： Allison quick ,吴晓江

生命问题是解释为什么某些物体表现出我们认为无生命的行为,而另一些物体独特地表现出我们认为有生命的行为的问题。对无生命物体和有生命物体的差异所作的各种各样的解释,是在不同的本体论和认识论的见解及其持续不断的争论的基础上形... 详细信息

生命问题是解释为什么某些物体表现出我们认为无生命的行为,而另一些物体独特地表现出我们认为有生命的行为的问题。对无生命物体和有生命物体的差异所作的各种各样的解释,是在不同的本体论和认识论的见解及其持续不断的争论的基础上形成的。了解这些见解,可以提供一个了解生物学发展的基本框架。史密斯这本书的长处在于他试图用这样一个框架写一部生物学史。(该书一九七六年由伦敦麦克米伦公司出版——译者注) 这本书包括了从希腊以前到现在对生命的科学认识的主要理论活动。因此,它显然不能试图写成一部详细的历史,而是一个多少有点紧扣一个主题——这个主题由著者多方面地描写为从目的论转

关键词：还原论逻辑实证主义 C.V.m 生物学史史密斯机械论机械唯物主义生命形而上学机体论亚里士多德泛灵论万物有灵论

改善HIV/AIDS患者健康相关结果的营养评估、咨询和支持（NACS）干...

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Bacterial graphical user interface oriented by particle swarm optimization strategy for optimization of multiple type DFACTS for power quality enhancement in distribution system

作者： Am Tang T quick m Chung CA Wanke 王若愚 Tufts University School of Medicine Department of Public Health and Community MedicineNutrition/Infection Unit

【背景】虽然许多研究表明,在抗逆转录病毒治疗(ART)开始时严重到中度的消瘦可以很好地预测死亡率,但在ART开始时或之前的营养干预是否能改善预后仍不清楚。这篇综述分析了在资源有限的环境中营养评估、咨询和支持(NACS)干预措施的数据...

【背景】虽然许多研究表明,在抗逆转录病毒治疗(ART)开始时严重到中度的消瘦可以很好地预测死亡率,但在ART开始时或之前的营养干预是否能改善预后仍不清楚。这篇综述分析了在资源有限的环境中营养评估、咨询和支持(NACS)干预措施的数据。【方法】我们确定了2005年至2014年间发表的关于NACS干预措施有效性的文章,特别是其对五种结果的影响:死亡率、发病率、护理保留率、生活质量和/或预防艾滋病毒持续传播。我们对个别文章的整体质量进行了评级,并总结了证据和对每项结果的预期影响。【结果】21篇文章符合所有入选标准。证据的总体质量很差,主要是因为很少有研究旨在直接解决感兴趣的问题。只有两项研究是随机试验和适当的对照组。其余的是一种食物支持与另一种食物支持的随机研究,队列(非随机)研究,或单臂研究。个人研究质量的评分范围从"中等"到"较弱",整体证据质量从"一般"到"差"。我们将对所有结果的预期影响评为"不确定"【结论】迫切需要在资源有限的环境中进行严格、设计更好的研究,以了解单独营养评估和咨询的有效性,以及了解更好的食物支持方式(目标、时间、成分、形式和持续时间)以提高患者短期和长期保留率的研究在护理和治疗以及临床结果方面。

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Journal of Central South University 2017年第3期24卷 569-588页

作者： m.mohammadi m.montazeri S.Abasi Department of Electrical Engineering Borujerd Branch Islamic Azad University Borujerd Iran

This study proposes a graphical user interface(GUI) based on an enhanced bacterial foraging optimization(EBFO) to find the optimal locations and sizing parameters of multi-type DFACTS in large-scale distribution *** proposed GUI based toolbox,allows the user to choose between single and multiple DFACTS allocations,followed by the type and number of them to be *** EBFO is then applied to obtain optimal locations and ratings of the single and multiple *** is found to be faster and provides more accurate results compared to the usual PSO and *** obtained with mATLAB/Simulink simulations are compared with PSO,BFO and enhanced *** reveals that enhanced BFO shows quick convergence to reach the desired solution there by yielding superior solution *** results concluded that the EBFO based multiple DFACTS allocation using DSSSC,APC and DSTATCOm is preferable to reduce power losses,improve load balancing and enhance voltage deviation index to 70%,38% and 132% respectively and also it can improve loading factor without additional power loss.

关键词： distribution system power quality single type and multiple type DFACTS BFO algorithm particle swarm optimization(PSO)

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A Note on Optimal Foldover Four-level Factorials

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Acta mathematica Sinica,English Series 2016年第3期32卷 286-296页

作者： A.m.ELSAWAH m.A.AL-AWADY m.A.ABD ELGAWAD Hong QIN Department of mathematics Faculty of ScienceZagazig UniversityZagazig 44519Egypt Faculty of mathematics and Statistics Central China Normal UniversityWuhan 430079P.R.China Department of mathematics Faculty of ScienceBenha UniversityBenha 13518Egypt

The foldover is a quick and useful technique in construction of fractional factorial designs, which typically releases aliased factors or interactions. The issue of employing the uniformity criterion measured by the centered L2-discrepancy to assess the optimal foldover plans was studied for four-level design. A new analytical expression and a new lower bound of the centered L2-discrepancy for fourlevel combined design under a general foldover plan are respectively obtained. A necessary condition for the existence of an optimal foldover plan meeting this lower bound was described. An algorithm for searching the optimal four-level foldover plans is also developed. Illustrative examples are provided, where numerical studies lend further support to our theoretical results. These results may help to provide some powerful and efficient mgorithms for searching the optimal four-level foldover plans.

关键词： Centered L2-discrepancy foldover plan optimal foldover plan combined design lower bounds

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