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A review:the mechanism of plant-derived polysaccharides on osteoblasts and osteoclasts

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未来食品学报(英文) 2024年第3期4卷 183-192页

作者： mengjie Ren adel F.Ahmed meng Li menghan Li Zhiruo Yan Jinmei Wang National R&d Center for Edible Fungus Processing Technology Henan UniversityKaifeng 475004China Joint International Research Laboratory of Food&medicine Resource Function Henan ProvinceKaifeng 475004China medicinal and Aromatic Plants Researches department Horticulture Research InstituteAgricultural Research CenterGiza 12511Egypt

Bone loss and deterioration of bone microarchitecture would increase the bone fragility and fracture risk,leading to the *** and more evidences proved that plant-derived polysaccharides could have a remarkable influence on osteoblasts and osteoclasts,exerting anti-osteoporosis *** to the previous research,the extract of Cibotium barumoz,Achyranthes bidentata,Curculigo orchioides,Epimedium brevicornum,Angelica sinensis,Polygonatum sibiricum,dendrobium officinale,morinda officinalis,Nelumbo mucifera,diospyros kaki,Hordeum vulgare,Cistanche deserticola,Commiphora myrrha and other plant-derived polysaccharides could benefit to the osteoblasts and *** essential mechanisms are mainly related to the activation or inhibition of many factors,including runt-related transcription factor 2(Runx2),B-catenin,osterix(Osx),activator protein-1(AP-1),osteocalcin(OCN/BGP),alkaline phosphatase(ALP),osteopontin(OPN),bone morphogenetic protein(BmP),phosphatidylinositol 3-kinase(PI3K)/C-Jun N-terminal kinase(JNK)/extracellular regulated protein kinase(ERK),osteoprotegerin(OPG),receptor activator of nuclear factor-kB(RANK),monocyte/macrophage colony-stimulating factor(m-CSF),tumor necrosis factor receptor-associated factor 6(TRAF-6),receptor activator of nuclear factor(NF)-KB ligand(RANKL),nuclear factor of activated T cells 1(NFATc1),c-Fos,matrix metallopeptidase-9(mmP-9),glycogen synthase kinase 3β(GSK3B)/B-catenin,nuclear factor E2-related factor 2(Nf2),as well as these related pathways,such as Wnt/p-catenin,BmP-2/SmAd1/5/8,PI3K/AKT,OPG/RANKL/RANK,NF-κB,mAPKs,*** plant-derived polysaccharides could improve the dynamic balance of bone formation and resorption through promoting the differentiation and maturation of osteoblast or inhibiting its *** reviewed plant-derived polysaccharides and their regulating mechanisms on the osteoclasts and osteoblasts provide the evidences for the development of osteoporosis therapeutics.

关键词： Osteoporosis Plant-derived polysaccharides Osteogenesis promotion Osteoclasts inhibition

multiphysics simulation of VVER-1200 fuel performance during normal operating conditions

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Nuclear Science and Techniques 2023年第2期34卷 139-152页

作者： Khaled m.Yassin m.ham.d H.Hassan mohammad m.Ghoneim mostafa S.Elkolil adel Alyan Said A.Agamy Nuclear Research Center Egyptian Atomic Energy AuthorityAbo Zaabal 13759CairoEgypt department of Nuclear and Radiological Engineering Faculty of EngineeringAlexandria UniversityAlexandria 21544Egypt Faculty of Engineering Egyptian Russian UniversityBadr 11829Egypt

Nuclear fuel performance modeling and simulation are critical tasks for nuclear fuel design optimization and safety analysis under normal and transient *** performance is a complicated phenomenon that involves thermal,mechanical,and irradiation mechanisms and requires special multiphysics *** this study,a fuel performance model was developed using the COmSOL multiphysics *** modeling was performed for a 2d axis-symmetric geometry of a UO2fuel pellet in the E110 clad for VVER-1200 *** modeling considers all relevant phenomena,including heat generation and conduction,gap heat transfer,elastic strain,mechanical contact,thermal expansion,grain growth,densification,fission gas generation and release,fission product swelling,gap/plenum pressure,and cladding thermal and irradiation *** model was validated using a code-to-code evaluation of the fuel pellet centerline and surface temperatures in the case of constant power,in addition to validation of fission gas release(FGR)*** prediction proved that the model could perform according to previously published VVER nuclear fuel performance parameters.A sensitivity study was also conducted to assess the effects of uncertainty on some of the model *** model was then used to predict the VVER-1200 fuel performance parameters as a function of burnup,including the temperature profiles,gap width,fission gas release,and plenum pressure.A compilation of related material and thermomechanical models was conducted and included in the modeling to allow the user to investigate different material/performance *** the model was developed for normal operating conditions,it can be modified to include off-normal operating conditions.

关键词： VVER-1200 Fuel performance COmSOL code Zr-1%Nb cladding UO2 fuel rod

Gauss Gradient and SURF Features for Landmine detection from GPR Images

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Computers, materials & Continua 2022年第6期71卷 4457-4486页

作者： Fatma m.El-Ghamry Walid El-Shafai mahmouad I.Abdalla Ghada m.El-Banby Abeer d.Algarni moawad I.dessouky adel S.Elfishawy Fathi E.Abd El-Samie Naglaa F.Soliman department of Electronics and Communications Engineering Faculty of EngineeringZagazig UniversityZagazigSharqia44519Egypt department of Electronics and Electrical Communications Engineering Faculty of Electronic EngineeringMenoufia UniversityMenoufia32952Egypt department of Industrial Electronics and Control Engineering Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt department of Information Technology College of Computer and Information SciencesPrincess Nourah Bint Abdulrahman UniversityRiyadhSaudi Arabia

Recently,ground-penetrating radar(GPR)has been extended as a well-known area to investigate the subsurface ***,its output has a low resolution,and it needs more processing for more *** paper presents two algorithms for landmine detection from GPR *** first algorithm depends on a multi-scale technique.A Gaussian kernel with a particular scale is convolved with the image,and after that,two gradients are estimated;horizontal and vertical ***,histogram and cumulative histogram are estimated for the overall gradient *** bin values on the cumulative histogram are used for discrimination between images with and without ***,a neural classifier is used to classify images with cumulative histograms as feature *** second algorithm is based on scale-space analysis with the number of speeded-up robust feature(SURF)points as the key parameter for *** addition,this paper presents a framework for size reduction of GPR images based on decimation for efficient *** further classification steps can be performed on images after *** sensitivity of classification accuracy to the interpolation process is studied in detail.

关键词： GPR images cumulative histogram gradient image neural classifier SURF

An efficient energy-management strategy for a dC microgrid powered by a photovoltaic/fuel cell/battery/supercapacitor

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Clean Energy 2022年第6期6卷 827-839页

作者： Furqan A.Abbas adel A.Obed mohammed A.Qasim Salam J.Yaqoob Seydali Ferahtia department of Electrical Engineering Electrical Engineering Technical CollegeMiddle Technical UniversityBaghdad 10001Iraq department of Nuclear Power Plants and Renewable Energy Sources Ural Federal University19 Mira St620002 YekaterinburgRussia department of Projects and Engineering Services Ministry of HealthBaghdad 10001Iraq department of Research and Education Authority of the Popular CrowdPrime MinisterBaghdad 10001Iraq Laboratore d’Analyse des Signaux et Systemes Department of Electrical EngineeringUniversity of M’silaMsila 28000Algeria

The outcome of this paper is to suggest an efficient energy-management strategy(EmS)for a direct-current(dC)microgrid(mG).The typical mG is composed of two renewable energy sources[photovoltaic(PV)systems and fuel cells(FCs)]and two energy-storage elements(lithium-ion battery and supercapacitor).An EmS was proposed to ensure optimal bus voltage with a power-sharing arrangement between the load and the *** a result,in the suggested dC mG,non-linear flatness control theory was used instead of the traditional proportional-integral control *** suggested EmS is intended to supply high power quality to the load under varying load conditions with fluctuating solar irradiation while considering the FC *** validate and prove the effectiveness of the proposed EmS,a mATLAB®environment was *** addition,the output power of the PV system was maximized using the particle swarm optimization algorithm as a maximum power point tracking(mPPT)technique to track the mPP of the 3000-W PV system under different irradiance *** results show that the suggested EmS delivers a stable and smooth dC bus voltage with minimum overshoot value(0.1%)and improved ripple content(0.1%).As a result,the performance of the dC mG was enhanced by employing the flatness control theory,which provides higher power quality by stabilizing the bus voltage.

关键词： photovoltaic fuel cell lithium energy management flatness control supercapacitor non-linear control

The Impact of medical Profession Type, Gender, and Years of Experience on Thinking Styles: What Are the Implications for Patient Safety?

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Journal of Behavioral and Brain Science 2022年第11期12卷 569-588页

作者： adel Omar Bataweel Patient Safety and Risk management Administration King Fahad Medical City Riyadh Kingdom of Saudi Arabia

Background: Healthcare providers were faced daily with many decision-making that impacted patients’ safety. According to dual process theory, there were two types of thinking: Experiential style (ES) and Rational Style (RS). Both thinking styles had an impact on individuals’ decisions making. Therefore, the aim of this study was to find out nurses’ and physicians’ styles of thinking and how this impacted patients’ safety. design: A cross-sectional study. methods: Nurses and physicians sample of adults (n = 308), 190 (61.7%) of the sample were nurses and 118 (38.3%) of the sample were physicians. Participants completed a self-report online survey, which included demographic information followed by questionnaires to measure thinking style and a cognitive puzzle to see if the medical error was associated with certain styles of thinking. Results: The main findings were that nurses (m = 2.41, Sd = 0.37) had significantly higher scores compared to physicians (m = 2.29, Sd = 0.39) in their ES, t(305) = 2.73, p = 0.007;with medium effect size, d = 0.37692. Conclusion: Nurses differed from physicians in ES where nurses had a significantly higher score than physicians which could be positive for patients’ safety as higher ES would report errors compared to lower ES.

关键词： Patient Safety Thinking Style Rational Style Experiential Style medical Error

Assessing the impact of artificial recharge on groundwater in an overexploited aquifer: A case study in the Cheria Basin, North-East of Algeria

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地下水科学与工程:英文版 2023年第3期11卷 263-277页

作者： mouna djellali Omar Guefaïfia Chemsedinne Fehdi adel djellali Amor hamad Sedimentary Environment Mineral and Water Resources of Eastern Algeria LaboratoryDepartment of Earth sciences and universeLarbi Tebessi University12002 TebessaAlgeria Environmental laboratory Mining instituteLarbi Tebessi University12002 TebessaAlgeria

The Cheria region in Northeastern Algeria has been facing aquifer overexploitation by the agricultural sector and prolonged droughts,resulting in a considerable decline in groundwater *** study investigates the feasibility of implementing artificial recharge techniques to replenish the Eocene aquifer which serves as the primary water source in the Cheria region.A 3d transient numerical model,based on the finite difference method,was used to simulate groundwater flow from 2021 to 2031 using Visual mOdFLOW *** the modelling process,three scenarios were considered:(1)including pumping without a recharge,(2)recharge of the entire area through efficient infiltration without pumping,and(3)artificial recharge using river water infiltration basins at two sites,draa douamis sinkholes and Eocene limestone *** simulation results showed that aquifer exploitation without recharge caused significant drawdowns,which were 3 m to 7 m in the north-eastern part and 8 m to 12 m in the central and southern *** contrast,the second scenario,involving recharge without pumping,showed a rise in groundwater levels of 2 m to 2.7 m in the north-eastern part and 3 m to 3.62 m in the central and southern *** third scenario,employing artificial recharge,indicated a positive response to artificial recharge,with increased piezometric levels at the proposed sites,signifying a beneficial impact on the *** findings underline the potential of artificial recharge as a promising approach to address the groundwater depletion and environmental issues in the Cheria Basin.

关键词： Eocene limestone Piezometric level Numerical simulation Visual mOdFLOW Flex Artificial recharge

deep learning acceleration of multiscale superresolution localization photoacoustic imaging

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Light(Science & Applications) 2022年第6期11卷 1166-1177页

作者： Jongbeom Kim Gyuwon Kim Lei Li Pengfei Zhang Jin Young Kim Yeonggeun Kim Hyung ham Kkim Lihong V.Wang Seungchul Lee Chulhong Kim departments of Electrical Engineering Mechanical EngineeringConvergence IT Engineeringand Interdisciplinary Bioscience and BioengineeringGraduate School of Artificial IntelligenceMedical Device Innovation CenterPohang University of Science and Technology(POSTECH)77 Cheongam-roNam-guPohangGyeongbuk 37673Republic of Korea Caltech Optical Imaging Laboratory Andrew and Peggy Cherng Department of Medical EngineeringDepartment of Electrical EngineeringCalifornia Institute of Technology1200 E.California Blvd.MC 138-78PasadenaCA 91125USA School of Precision Instruments and Optoelectronics Engineering Tianjin University92 Weijin RoadNankai DistrictTianjin 300072China Opticho 532CHANGeUP GROUND87 Cheongam-roNam-guPohangGyeongsangbuk 37673Republic of Korea

A superresolution imaging approach that localizes very small targets,such as red blood cells or droplets of injected photoacoustic dye,has significantly improved spatial resolution in various biological and medical imaging ***,this superior spatial resolution is achieved by sacrificing temporal resolution because many raw image frames,each containing the localization target,must be superimposed to form a sufficiently sampled high-density superresolution ***,we demonstrate a computational strategy based on deep neural networks(dNNs)to reconstruct high-density superresolution images from far fewer raw image *** localization strategy can be applied for both 3d label-free localization optical-resolution photoacoustic microscopy(OR-PAm)and 2d labeled localization photoacoustic computed tomography(PACT).For the former,the required number of raw volumetric frames is reduced from tens to fewer than *** the latter,the required number of raw 2d frames is reduced by 12 ***,our proposed method has simultaneously improved temporal(via the dNN)and spatial(via the localization method)resolutions in both label-free microscopy and labeled ***-learning powered localization PA imaging can potentially provide a practical tool in preclinical and clinical studies requiring fast temporal and fine spatial resolutions.

关键词： deep frames networks

FPGA-based hardware-in-the-loop for multi-domain simulation

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International Journal of modeling, Simulation, and Scientific Computing 2019年第4期10卷 20-37页

作者： Abdelouahab d.Benhamadouche Farid djahli adel Ballouti Abdeslem Sahli department of Electronic University Ferhat Abbas Setif 1 Setif 19000Algeria Faculty of Technology University Mohamed Boudiaf of M’Sila M’Sila 28000Algeria

In this paper,we present a new approach for complex system design,which allows rapid,efficient and low-cost *** approach can simplify designing tasks and go faster from system modeling to effective hardware *** multi-domain systems requires different engineering competences and several tools,our approach gives a unique design environment,based on the use of VHdL-AmS modeling language and FPGA device within the same design *** approach is intended to enhance hardware-in-the-loop(HIL)practices with a more realistic simulation which improve the verification process in the system design *** paper describes the implementation of a software/hardware platform as a practical support for our approach,the feasibility and the benefits of this approach are demonstrated through a practical case study for power converter *** obtained results show that the developed method achieves significant speed-up compared with conventional simulation,with a minimum used resources and minimum latency.

关键词： Hardware-in-the-loop(HIL)simulation multi-domain system verification system control field-programmable gate array(FPGA) VHdL-AmS

Sensitive and fast response ethanol chemical sensor based on as-grown Gd_2O_3 nanostructures

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Journal of Rare Earths 2015年第2期33卷 214-220页

作者： m.m.Abdullah mohammed m.Rahman Houcine Bouzid m.Faisal Sher Bahadar Khan S.A.Al-Sayari adel A.Ismail Promising Centre for Sensors and Electronic devices (PCSEd) College of Science and Arts Najran University P.O. Box-1988Najran 11001 Saudi Arabia Center of Excellence for Advanced materials Research (CEAmR) & Chemistry department King Abdulaziz University P.O. Box 80203Jeddah 21589 Saudi Arabia Laboratory of Ferroelectric materials Faculty of Sciences of Sfax Route Soukra Km 35B.P. 802 F-3018 Sfax Tunisia College of Science and Arts-Sharoura Najran University P.O. Box-1988Najran 11001 Saudi Arabia Central metallurgical Research and development Institute (CmRdI) P.O.Box: 87 Helwan 11421 Cairo Egypt

Well crystalline gadolinium oxide（Gd2O3） nanostructures were grown by annealing the hydrothermally as-prepared nanostructures without using any template. microscopic studies of Gd2O3 nanostructures were recorded along the [111] direction due to the clearly resolved interplanar distance d（222）-0.31 nm of the cubic crystal structure Gd2O3. Sensing mechanism of Gd2O3 as efficient electron mediator for the detection of ethanol was explored. As-fabricated sensor demonstrated the high-sensitivity of -0.266 μAm/m/cm2 with low detection limit（-52.2 μmol/L） and correlation coefficient（r^2, 0.618）. To the best of our knowledge, this was the first report for the detection of ethanol using as-grown（at 1000 oC） Gd2O3 nanostructures by simple and reliable Ⅰ-Ⅴ technique and rapid assessment of the reaction kinetics（in the order of seconds）. The low cost of the starting reagents and the simplicity of the synthetic route made it a promising chemical sensor for the detection of various toxic analytes, which are not environmentally safe.

关键词： growth Gd2O3 nanostructures ethanol Ⅰ-Ⅴ technique chemical sensing rare earths