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Ground-state mass of ^(22)Al and test of state-of-the-art ab initio calculations

Chinese Physics C 2024年第3期48卷 72-78页

作者：孙铭泽于越王新鹏王猛李健国张玉虎 K.Blaum 陈祖毅陈瑞九邓涵宇付超义葛文文黄文嘉焦红扬李红蕙李宏福罗胤芳廖挺 YuALitvinov 司敏帅鹏史金阳王茜邢元明徐星徐瑚珊许甫荣袁琪 T.Yamaguchi 颜鑫亮杨建成原有进周小红周旭张敏曾奇 CAS Key Laboratory of high Precision Nuclear Spectroscopy Institute of Modern PhysicsChinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China max-Planck-Institut für Kernphysik Saupfercheckweg 169117 HeidelbergGermany GSI helmholtzzentrum für Schwerionenforschung Planckstraße 164291 DarmstadtGermany Advanced Energy Science and Technology Guangdong Laboratory Huizhou516007China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Department of Physics Saitama UniversitySaitama 338-8570Japan School of Nuclear Science and Engineering East China University of TechnologyNanchang 330013China

The ground-state mass excess of the T_(z)=−2 drip-line nucleus ^(22)Al is measured for the first time as 18103(10)keV using the newly-developed Bρ-defined isochronous mass spectrometry method at the cooler storage ring in *** new mass excess value allowed us to determine the excitation energies of the two low-lying 1+states in ^(22)Al with significantly reduced uncertainties of 51 *** compared to the analogue states in its mirror nucleus ^(22)F,the mirror energy differences of the two 1^(+)states in the ^(22)Al-^(22)F mirror pair are determined to be−625(51)keV and−330(51)*** excitation energies and mirror energy differences are used to test the state-of-the-art ab initio valence-space in-medium similarity renormalization group calculations with four sets of interactions derived from the chiral effective field *** mechanism leading to the large mirror energy differences is investigated and attributed to the occupation of theπs_(1/2) orbital.

关键词： nuclear mass Bρ-defined ImS mirror energy difference ab initio VS-ImSRG calculations chiral interactions

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Evaluation of the seismic behavior of reinforced concrete structures with flat slab-column gravity frame and shear walls through nonlinear analysis methods

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Earthquake Engineering and Engineering Vibration 2024年第3期23卷 713-726页

作者： m.A.Najafgholipour S.heidarian Radbakhsh E.Erfani Department of Civil and Environmental Engineering Shiraz University of TechnologyShiraz ***Iran Department of Building Civiland Environmental EngineeringConcordia UniversityMontréal H3G 1M8Canada

This paper presents an investigation of the seismic behavior of reinforced concrete(RC)structures in which shear walls are the main lateral load-resisting elements and the participation of flat slab floor systems is not considered in the seismic design *** this regard,the behavior of six prototype structures(with different heights and plan layouts)is investigated through nonlinear static and time history analyses,implemented in the OpenSees *** results of the analyses are presented in terms of the behavior of the slab-column connections and their mode of failure at different loading ***,the global response of the buildings is discussed in terms of some parameters,such as lateral overstrength due to the gravity flat slab-column *** to the nonlinear static analyses,in structures in which the slab-column connections were designed only for gravity loads,the slab-column connections exhibited a punching mode of failure even in the early stages of ***,the punching failure was eliminated in structures in which a minimum transverse reinforcement recommended in ACI 318(2019)was provided in the slabs at joint ***,despite neglecting the contribution of gravity flat slab-column frames in the lateral load resistance of the structures,a relatively significant overstrength was imposed on the structures by the gravity frames.

关键词： RC flat slab-column frames seismic behavior nonlinear analysis time history analysis

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Nonuniform Dependence on the Initial Data for Solutions of Conservation Laws

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Communications on Applied mathematics and Computation 2024年第1期6卷 489-500页

作者： John m.holmes Barbara Lee Keyfitz Department of mathematics The Ohio State UniversityColumbusOH43210USA

In this paper,we study systems of conservation laws in one space *** prove that for classical solutions in Sobolev spaces h^(s),with s>3/2,the data-to-solution map is not uniformly *** results apply to all nonlinear s... 详细信息

关键词： Conservation laws Data-to-solution map Nonuniform dependence

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Sparse-Grid Implementation of Fixed-Point Fast Sweeping WENO Schemes for Eikonal Equations

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Communications on Applied mathematics and Computation 2024年第1期6卷 3-29页

作者： Zachary m.miksis Yong-Tao Zhang Department of Applied and Computational mathematics and Statistics University of Notre DameNotre DameIN46556USA

Fixed-point fast sweeping methods are a class of explicit iterative methods developed in the literature to efficiently solve steady-state solutions of hyperbolic partial differential equations(PDEs).As other types of fast sweeping schemes,fixed-point fast sweeping methods use the Gauss-Seidel iterations and alternating sweeping strategy to cover characteristics of hyperbolic PDEs in a certain direction simultaneously in each sweeping *** resulting iterative schemes have a fast convergence rate to steady-state ***,an advantage of fixed-point fast sweeping methods over other types of fast sweeping methods is that they are explicit and do not involve the inverse operation of any nonlinear local ***,they are robust and flexible,and have been combined with high-order accurate weighted essentially non-oscillatory(WENO)schemes to solve various hyperbolic PDEs in the *** multidimensional nonlinear problems,high-order fixed-point fast sweeping WENO methods still require quite a large amount of computational *** this technical note,we apply sparse-grid techniques,an effective approximation tool for multidimensional problems,to fixed-point fast sweeping WENO methods for reducing their computational ***,we focus on fixed-point fast sweeping WENO schemes with third-order accuracy(Zhang et al.2006[41]),for solving Eikonal equations,an important class of static hamilton-Jacobi(h-J)*** experiments on solving multidimensional Eikonal equations and a more general static h-J equation are performed to show that the sparse-grid computations of the fixed-point fast sweeping WENO schemes achieve large savings of CPU times on refined meshes,and at the same time maintain comparable accuracy and resolution with those on corresponding regular single grids.

关键词： Fixed-point fast sweeping methods Weighted essentially non-oscillatory(WENO)schemes Sparse grids Static hamilton-Jacobi(h-J)equations Eikonal equations

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human leukocyte antigen compatibility and incidence of donorspecific antibodies in pediatric liver transplant recipients

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World Journal of Gastroenterology 2024年第33期30卷 3837-3845页

作者： melina U melere Flavia h Feier Jorge Neumann Antônio N Kalil Juliana de m montagner Luiza S Nader Carolina S da Silva marco Aurélio F Junior Gabriela P Coral Guilherme P Bobsin Cristina T Ferreira Department of hepatology and Liver Transplantation Santa Casa de Porto AlegrePorto Alegre 90050170Rio Grande do SulBrazil Department of hepato-biliary-pancreatic Surgery and Liver Transplantation Irmandade Santa Casa de Misericórdia de Porto AlegrePorto Alegre 90020-090Rio Grande do SulBrazil Postgraduation Program in medicine:hepatology Federal University of Health Sciences of Porto AlegrePorto Alegre 90050-170Rio Grande do SulBrazil Laboratory of Transplantation Immunology Irmandade Santa Casa de Misericórdia de Porto AlegrePorto Alegre 90020-090Rio Grande do SulBrazil

BACKGROUND Antibody-mediated rejection following liver transplantation(LT)has been increasingly recognized,particularly with respect to the emergence of de novo donor-specific antibodies(DSAs)and their impact on graft *** substantial evidence for adult populations exists,research focusing on pediatric LT outcomes remains *** To investigate the prevalence of human leukocyte antigen(hLA)mismatches and DSA and evaluate their association with rejection episodes after pediatric *** A cohort of pediatric LT recipients underwent hLA testing at Santa Casa de Porto Alegre,Brazil,between December 2013 and December *** patients who survived for>30 days after LT with at least one DSA analysis were *** classes I and II and cross-matches were *** presence of de novo DSA(dnDSA)was evaluated at least 3 months after LT using the Luminex®single antigen bead method,with a positive reaction threshold set at 1000 *** episodes were confirmed by liver *** Overall,67 transplanted children were analyzed;61 received grafts from living donors,85%of whom were related to ***-transplant DSA(class I or II)was detected in 28.3%of patients,and dnDSA was detected in 48.4%.The median time to DSA detection after LT was 19.7[interquartile range(IQR):4.3-35.6]*** rejection occurred in 13 patients at follow-up,with C4d positivity observed in 5/13 Liver *** median time to rejection was 7.8(IQR:5.7-12.8)*** presence of dnDSA was significantly associated with rejection(36%vs 3%,Phe rejection-free survival rates at 12 and 24 months were 76%vs 100%and 58%vs 95%for patients with dnDSA anti-DQ vs those without,*** Our findings highlight the importance of incorporating DSA assessment into pre-and post-transplantation protocols for pediatric LT *** implications may include immunosuppression minimization strategies based on this analysis in pediatric LT recip

关键词： human leukocyte antigens Donor-specific antibodies Liver transplantation Pediatric Rejection

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highly toxic Aβ begets more Aβ

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Neural Regeneration Research 2024年第9期19卷 1871-1872页

作者： merc m.Kemeh Noel D.Lazo Gustaf h.Carlson School of Chemistry and Biochemistry Clark UniversityWorcesterMAUSA

Alzheimer’s disease(AD)is the most common form of dementia-the 7th leading cause of death *** the tissue level,AD is characterized by the presence of extracellular amyloid plaques that are comprised primarily of the amyloid-βpeptide(Aβ),and by intraneuronal neurofibrillary tangles composed of *** genetics of early-onset AD and longitudinal brain-imaging studies of late-onset AD indicate that extracellular Aβdeposition,in general,precedes neurofibrillary tangle formation in neurons(hampel et al.,2021;Young-Pearse et al.,2023).

关键词： Aβ tau Alzheimer death

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hematological malignancies in Sickle Cell Disease Patients: Report of Four Cases in Togo and Literature Review

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Open Journal of Blood Diseases 2024年第1期14卷 31-41页

作者： Padaro Essohana Guedenon m. Koffi magnang hèzouwè Womey m. C. Kodzovi Layibo Yao Kalaissi mandjamana Agate R. Pikiliwè Department of hematology Campus Teaching Hospital University of Lomé Lomé Togo Department of Pediatrics Sylvanus Olympio Teaching Hospital University of Lomé Lomé Togo National Center of Research and Treatement of Sickle Cell Disease Patients (CNRSD) Lomé Togo Department of hematology Sylvanus Olympio Teaching Hospital University of Lomé Lomé Togo

Background: hemopathies were rarely observed in major sickle cell disease patients some thirty years ago, probably due to the high mortality rate among the latter as a result of progressive complications. Thanks to advances in the management of sickle cell disease, patients' life expectancy has increased considerably, exposing them more frequently to neoplasia, including hematological malignancies. The increased risk of leukemogenesis is multifactorial and linked to the pathophysiological mechanisms of the clinical manifestations of sickle cell disease. Study Setting: The clinical haematology department of campus teaching hospital and the paediatric onco-haematology unit of Sylvanus Olympio teaching hospital in Lomé were used as study settings. Observations: Four hematologic malignancies were collected in a cohort of 5847 major sickle cell syndromes. The median age of the patients was 31.25 years (extremes: 14 and 58 years) and they were predominantly female (sex ratio m/F = 0.25). Two were on background therapy with hydroxyurea. Among the four patients, there were two cases of acute lymphocytic leukemia, including ALL3 in a 58-year-old SS woman and T-ALL2 in a 12-year-old SC. Then, a case of lymphocytic lymphoma in a 20-year-old SS man was reported and finally a case of chronic myelocytic leukemia in a 33-year-old woman of Sβ+ thalassaemia phenotype. Conclusion: To further report this coexistence, it is therefore essential to systematically consider hematological malignancies during major sickle cell syndromes even if there are similarities in the symptomatology of these two serious pathological situations.

关键词： hematological malignancies Sickle Cell Disease Lomé-Togo

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In vivo and in vitro study of resorbable magnesium wires for medical implants:mg purity,surface quality,Zn alloying and polymer coating

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Journal of magnesium and Alloys 2024年第6期12卷 2472-2488页

作者： K.Tesar J.Luňácková m.Jex m.Žaloudková R.Vrbová m.Bartoš P.Klein L.Vištejnová J.Dušková E.Filová Z.Sucharda m.Steinerová S.habr K.Balík A.Singh Department of materials Faculty of Nuclear Sciences and Physical EngineeringCzech Technical University in PragueTrojanova 13Prague 12000Czech Republic Institute of Physics Czech Academy of SciencesNa Slovance 2Prague 18221Czech Republic Institute of Dental medicine First Faculty of MedicineCharles University and General University Hospital in PragueKaterinská32Prague 12801Czech Republic Department of Physics Faculty of Nuclear Sciences and Physical EngineeringCzech Technical University in PragueBrehová7Prague 11519Czech Republic Department of Composites and Carbon materials Institute of Rock Structure and MechanicsCzech Academy of SciencesV Holešovickách 41Prague 18209Czech Republic Institute of Anatomy First Faculty of MedicineCharles UniversityU Nemocnice 3Prague 12800Czech Republic Biomedical Center Faculty of Medicine in PilsenCharles UniversityAlej Svobody 76Pilsen 32300Czech Republic Department of Pathological Physiology Faculty of Medicine in PilsenCharles UniversityAlej Svobody 7632300 PilsenCzech Republic Department of histology and Embryology Faculty of Medicine in PilsenCharles UniversityAlej Svobody 7632300 PilsenCzech Republic Institute of Pathology First Faculty of MedicineCharles University and General University Hospital in PragueStudnickova 2Prague 12800Czech Republic Department of Biomaterials and Tissue Engineering Institute of PhysiologyCzech Academy of SciencesVidenska 1083Prague 14200Czech Republic Research Center for Structural materials National Institute for Materials Science1-2-1 SengenTsukuba 305-0047Japan

magnesium is an excellent material in terms of biocompatibility and its corrosion products can serve as an active source for new bone ***,localized corrosion and h_(2)generation limit the potential of mg-based *** low-alloyed mg-Zn wires can strongly reduce problems with large h_(2)bubbles and improve the mechanical properties considerably while maintaining excellent long-term *** pickling and a polymer coating can be effectively used to lower the rate of in vivo *** this work,microstructural,mechanical,and in vitro characterization of 250μm and 300μm extruded wires made from ultra-pure mg,commercially pure mg,mg-0.15Zn,mg-0.4Zn and mg-1Zn was ***,mg-0.4Zn wires together with a variant coated with a copolymer of L-lactide andε-caprolactone were tested in vivo on artificially damaged Wistar rat *** on the observed mg-induced osteogenesis,polymer-coated mg wires with a small addition of Zn are a perspective material for bone-support applications,such as cerclage and fixation wires.

关键词： magnesium Resorbable mg wire mg-Zn implant degradation Biocompatibility study Zn grain boundary segregation

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Design of a large-scale model for wind tunnel test of a multiadaptive flap concept

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Chinese Journal of Aeronautics 2024年第2期37卷 58-80页

作者： mürüvvet Sinem SICIm DEmIRCI Rosario PECORA metin Orhan KAYA Aeronautical Engineering Department Istanbul Technical UniversityIstanbulTurkey Industrial Engineering Department University of Naples Federico IINapoliItaly

The design and application of morphing systems are ongoing issues compelling the aviation *** Clean Sky-program represents the most significant aeronautical research ever launched in Europe on advanced technologies for greening next-generation *** primary purpose of the program is to develop new concepts aimed at decreasing the effects of aviation on the environment,increasing reliability,and promoting eco-friendly *** ambitions are pursued through research on enabling technologies fostering noise and gas emissions reduction,mainly by improving aircraft aerodynamic *** the Clean Sky framework,a multimodal morphing flap device was designed based on tight industrial requirements and tailored for large civil aircraft *** flap is deployed in one unique setting,and its cross section is morphed differently in take-off and landing to get the necessary extra lift for the specific flight ***,during the cruise,the tip of the flap is deflected for load control and induced drag *** manufacturing the first flap prototype,a high-speed(ma=0.3),large-scale test campaign(geometric scale factor 1:3)was deemed necessary to validate the performance improvements brought by this novel system at the aircraft *** the other hand,the geometrical scaling of the flap prototype was considered impracticable due to the unscalability of the embedded mechanisms and actuators for shape ***,a new architecture was conceived for the flap model to comply with the scaled dimensions requirements,withstand the relevant loads expected during the wind tunnel tests and emulate the shape transition capabilities of the true-scale *** strategies were developed to effectively morph the model during wind tunnel tests while ensuring the robustness of each morphed configuration and maintaining adequate stiffness levels to prevent undesirable deviations from the intended aerodynamic ***,

关键词： morphing structures Smart aircraft morphing flap Adaptive systems Finger-like ribs Wind tunnel tests Large-scale morphing archi-tectures Variable camber airfoil

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Immunological Exploration of helicobacter pylori Serotype O_(2) O-Antigen by Using a Synthetic Glycan Library

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Chinese Journal of Chemistry 2024年第3期42卷 243-251页

作者： ming Zhao Guangzong Tian Chunjun Qin Xiaopeng Zou Peter h. Seeberger Jing hu Jian Yin Key Laboratory of Carbohydrate Chemistry and Biotechnology Ministry of EducationSchool of Biotechnology & School of Life Sciences and Health EngineeringJiangnan UniversityLihu Avenue 1800WuxiJiangsu214122 China Biomolecular Systems Department Max Planck Institute of Colloids and InterfacesAm Mühlenberg 1Potsdam14476 Germany Wuxi School of medicine Jiangnan UniversityLihu Avenue 1800WuxiJiangsu214122 China

helicobacter pylori(***)infection is a threat to human *** lipopolysaccharide(LPS)O-antigen holds promise for developing *** is meaningful to explore the immunological activity of oligosaccharides with different lengths and frameshifts for antigen ***,a glycan library of *** O2 O-antigen containing eight fragments is *** screening with *** O2 LPS sera and patients’sera by glycan microarray,the disaccharide hPO2G-2b and trisaccharide hPO2G-3a show strong antigenicity and then are separately conjugated with carrier protein *** glycoconjugates elicit a robust immunoglobulin G(IgG)immune response in *** anti-hPO2G-3a IgG antibodies possess a much stronger binding affinity with the LPS and bacteria of *** O2 than the anti-hPO2G-2b IgG *** is no cross-reaction between both sera IgG antibodies with LPS and bacteria of *** O1,O6,and *** results demonstrate the trisaccharide hPO2G-3a is a promising candidate for *** vaccine development.

关键词： Glycoconjugates helicobacter pylori Immunology microarrays O-antigen Oligosaccharides

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