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In Vivo measurement of Toxic Elements Using X-ray Fluorescence Analysis

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In Vivo Measurement of Toxic Elements Using X-ray Fluorescen...

Gammasphere上裂变丰中子核核结构若干前沿领域的新进展(Ⅱ:第三和第四部分)(英文)

第三十五届国际光谱会议

作者： F.E.mcNeill d.R.Chettle J.m.O’meara m.Popovic R.C.N.Studinski mcmaster University hamilton ontarioCanada mcmaster University hamilton ontarioCanada University of Guelph Guelph OntarioCanada mcmaster University hamilton OntarioCanada mcmaster University hamilton OntarioCanada

＜正＞A common method of monitoring toxic elements in the workplace is to perform measurements on blood and urine *** this technique has the advantage of being relatively simple,the resultant data tend to provide information only about recent *** is often long term exposure to a heavy metal toxin that correlates with adverse health *** addition,blood and urine are not direct measurements of

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原子核物理评论 2010年第3期27卷 363-389页

作者：罗亦孝 J.H.hamilton J.O.Rasmussen A.V.Ramayya C.Goodin A.V.daniel N.J.Stone 朱胜江 J.K.Hwang 刘少华 C.J.Beyer 李科 H.L.Crowell d.Al mehed S.Frauendorf A.Covello V.di mitrov 张敬业车兴来姜卓 d.Fong A.Gelberg I.Stefanescu A.Gargano E.F.Jones P.m.Gore I.Y.Lee G.m.Ter-Akopian Yu.Ts.Oganessian m.A.Stoyer R.donangelo 马文超 J.d.Cole J.Kormicki 张学谦 S.C.Wu J.Gilat T.N.Ginter S.J.Asztalos Physics department Vanderbilt University Nashville TN 37235 USA Lawrence Berkeley National Laboratory Berkeley CA 94720 USA Flerov Laboratory for Nuclear Reactions JINR Dubna Russia Joint Institute for Heavy Ion Research Oak Ridge TN 37831 USA department of Physics Oxford University Oxford OX1 3PU United Kingdom department of Physics and Astronomy University of Tennessee Knoxville Tennessee 37996 USA Physics department Tsinghua University Beijing 100084 China department of Physics University of Notre Dame Notre Dame IN 46556 USA Institut far Strahlenphysik FZD-Rossendorf Postfach 510119 D-01314 Dresden Germany dipartimento di Scienze Fisiche Universita di Napoli Federico II and Istituto Nazionale di Fisica Nuclear Complesso Universitario di Monte S. Angelo Via Cintia 80126 Napoli Italy Idaho Accelerator Center Idaho State University Pocatello ID-83209-8263 USA Institut fur Kernphysik Universitat zu Koln 50937 Kdln Germany department of Chemistry and Biochemistry University of Maryland MD 20742 USA Lawrence Livermore National Laboratory Livermore CA 94550 USA Instituto de Fisica Facultad de Ingenieria C. C. 30 11300 Montevideo Uruguay mississippi State University Drawer 5167 Mississippi State MS 39762 USA Idaho National Laboratory Bldg. IRCPL MS2114 Idaho Falls ID 83415 USA department of Physics National Tsing Hua University Hsinchu Taiwan 30013 China National Superconducting Cyclotron Laboratory Michigan State University East Lansing Michigan 48824 USA massachusetts Institute of Technology Cambridge Massachusetts 02139 USA

使用Gammasphere多探测器系统对252Cf裂变源瞬发γ射线进行γ-γ-γ和γ-γ(θ)符合测量,A～100(Z～40,N>56)丰中子核区关于形状过渡、形状共存和形状突变的深入研究获得了新的进展。奇-Z核的系统研究揭示了从Z=39(Y)同位素的轴对称大... 详细信息

使用Gammasphere多探测器系统对252Cf裂变源瞬发γ射线进行γ-γ-γ和γ-γ(θ)符合测量,A～100(Z～40,N>56)丰中子核区关于形状过渡、形状共存和形状突变的深入研究获得了新的进展。奇-Z核的系统研究揭示了从Z=39(Y)同位素的轴对称大四极形变到Z=43(Tc),44(Ru)和45(Rh)同位素中具有中等四极形变之大三轴形变的过渡。Nb(Z=41)同位素具有过渡核的特征。根据邻近同位素和同中素带交叉信息的系统性及推转壳模型(CSm)计算,Tc和Rh偶-N同位素中观察到的带交叉产生于一对h11/2中子的转动顺排。首次观察到100Nb(Z=41,N=59)的高自旋能级纲图和形变态,从而证实了100Nb中的形状共存,并确认,在Nb同位素链上,基态形状突变发生于N=58(球形)到N=59(大形变);而在Sr(Z=38),Y(Z=39)和Zr(Z=40)各同位素链上,基态形状突变均发生于N=59(球形)到N=60(大形变)。100Nb具有大形变基态,同现有理论预言相矛盾,其大形变的基态及转动带所具有的很大的和不规则的转动惯量具有重要的理论意义。对奇-质子Cs(Z=55)和La(Z=57)丰中子同位素八极激发的详细研究,发现了141,143,144Cs同位素链上电二极矩d0随中子数增加而减小的急剧变化,此前在145,147La中观察到的电二极矩d0的较缓和的减小似乎亦很陡地下延至148La。在Cs和La同位素中观察到的电二极矩d0的急剧下降很可能同偶-质子核146Ba和224Ra中观察到的电二极矩d0的急剧下降相类似,后者已获反射非对称平均场壳修正理论的成功解释。实验证明,141Cs具有很大电二极矩d0。141Cs和142Xe中观测到的很大的电二极矩d0和仅在141Cs中观察到的电二极矩d0的simplex量子数相关性需要进一步的理论研究。根据转动频率比值ω-(I)/ω+(I)的检定,同Xe同位素一样,认定Cs同位素中包括号143Cs的八极激发为八极振动,而在La同位素中存在八极形变。

关键词：形状过渡轴对称形状三轴形变形状突变带交叉奇-质子八极激发 B(E1)/B(E2)比值电二极矩d0 二极矩的下降八极振动 Cs,La同位素

The exploitation of epichloae endophytes for agricultural benefit

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Fungal diversity 2013年第3期60卷 171-188页

作者： Linda J.Johnson Anouck C.m.de Bonth Lyn R.Briggs John R.Caradus Sarah C.Finch damien J.Fleetwood Lester R.Fletcher david E.Hume Richard d.Johnson Alison J.Popay Brian A.Tapper Wayne R.Simpson Christine R.Voisey Stuart d.Card AgResearch Ltd Grasslands Research CentreTennent DrivePalmerston North 4442New Zealand AgResearch Ltd Ruakura Research CentreEast StreetHamilton 3214New Zealand AgResearch Ltd Lincoln Research CentreCorner Springs Road and Gerald StreetLincoln 8140New Zealand AgResearch Laboratory of Structural Biology School of Biological SciencesUniversity of Auckland3a Symonds StreetAuckland 1142New Zealand Grasslanz Technology Ltd Tennent DrivePalmerston North 4474New Zealand

Epichloae endophytes of family Clavicipitaceae(comprising genera Epichloëand Neotyphodium)are fungal symbionts of Pooideae *** associations formed,range from mutually beneficial to antagonistic and the nature of this relationship is dependent upon the importance of vertical(via host seeds)versus horizontal(ascospore mediated)transmission of the *** endophytes can enhance their hosts’survival through protection from abiotic and biotic stresses and can thus be utilized in an agricultural ***-safe grass-endophyte associations that confer bio-protective properties for increased pasture persistence and productivity have been developed and *** of the crucial drivers underpinning the selection of epichloae strains for commercial development is endophyte derived *** potential of next generation endophytes is determined by testing a number of attributes such as agronomic fitness,animal and food safety as well as compatibility with host plants of *** research supports these activities by focusing on elucidating mechanisms of compatibility between host and fungal symbiont,as well as investigating other molecular drivers of symbiosis such as siderophore mediated iron-uptake,fungal signalling,fungal growth in host plants and fungal secondary *** review weaves together the different strands of multidisciplinary research aimed at ultimately exploiting epichloae endophytes for increased pasture performance.

关键词： Epichloë Neotyphodium Pooideae Symbiosis Secondary metabolite Toxicology

Search for the doubly heavy baryon Ξ_(bc)^(+)→ decaying to J/ψΞ_(c)^(+)

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中国物理C:英文版 2023年第9期47卷 1-13页

作者： R.Aaij A.S.W.Abdelmotteleb C.Abellan Beteta F.Abudinén T.Ackernley B.Adeva m.Adinolfi H.Afsharnia C.Agapopoulou C.A.Aidala S.Aiola Z.Ajaltouni S.Akar K.Akiba J.Albrecht F.Alessio m.Alexander A.Alfonso Albero Z.Aliouche P.Alvarez Cartelle S.Amato J.L.Amey Y.Amhis L.An L.Anderlini m.Andersson A.Andreianov m.Andreotti d.Andreou d.Ao F.Archilli A.Artamonov m.Artuso E.Aslanides m.Atzeni B.Audurier S.Bachmann m.Bachmayer J.J.Back A.Bailly-reyre P.Baladron Rodriguez V.Balagura W.Baldini J.Baptista de Souza Leite m.Barbetti R.J.Barlow S.Barsuk W.Barter m.Bartolini F.Baryshnikov J.m.Basels G.Bassi B.Batsukh A.Battig A.Bay A.Beck m.Becker F.Bedeschi I.B.Bediaga A.Beiter V.Belavin S.Belin V.Bellee K.Belous I.Belov I.Belyaev G.Bencivenni E.Ben-Haim A.Berezhnoy *** d.Berninghoff H.C.Bernstein C.Bertella A.Bertolin C.Betancourt F.Betti Ia.Bezshyiko S.Bhasin J.Bhom L.Bian m.S.Bieker N.V.Biesuz S.Bifani P.Billoir A.Biolchini m.Birch F.C.R.Bishop A.Bitadze A.Bizzeti m.P.Blago T.Blake F.Blanc S.Blusk d.Bobulska J.A.Boelhauve O.Boente Garcia T.Boettcher A.Boldyrev N.Bondar S.Borghi m.Borsato J.T.Borsuk S.A.Bouchiba T.J.V.Bowcock A.Boyer C.Bozzi m.J.Bradley S.Braun A.Brea Rodriguez J.Brodzicka A.Brossa Gonzalo d.Brundu A.Buonaura L.Buonincontri A.T.Burke C.Burr A.Bursche A.Butkevich J.S.Butter J.Buytaert W.Byczynski S.Cadeddu H.Cai R.Calabrese L.Calefice S.Cali R.Calladine m.Calvi m.Calvo Gomez P.Camargo magalhaes P.Campana d.H.Campora Perez A.F.Campoverde Quezada S.Capelli L.Capriotti A.Carbone G.Carboni R.Cardinale A.Cardini I.Carli P.Carniti L.Carus A.Casais Vidal R.Caspary G.Casse m.Cattaneo G.Cavallero V.Cavallini S.Celani J.Cerasoli d.Cervenkov A.J.Chadwick m.G.Chapman m.Charles Ph.Charpentier C.A.Chavez Barajas m.Chefdeville C.Chen S.Chen A.Chernov S.Chernyshenko V.Chobanova S.Cholak m.Chrzaszcz A.Chubykin V.Chulikov P.Ciambrone m.F.Cicala X.Cid Vidal G.Ciezarek G.Ciullo P.E.L.Clarke m.Clemencic H.V.Cliff J.Closier J.L.Cobbledick V.Coco J.A.B.Coelho J.Cogan E.Cogneras L.Cojocariu P.Collins T.Colombo L.Congedo A.Contu N.Cooke Centro Brasileiro de Pesquisas Físicas(CBPF) Rio de JaneiroBrazil Universidade Federal do Rio de Janeiro(UFRJ) Rio de JaneiroBrazil Center for High Energy Physics Tsinghua UniversityBeijingChina Institute Of High Energy Physics(IHEP) BeijingChina School of Physics State Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijingChina University of Chinese Academy of Sciences BeijingChina Institute of Particle Physics Central China Normal UniversityWuhanHubeiChina Université Savoie mont Blanc CNRSIN2P3-LAPPAnnecyFrance UniversitéClermont Auvergne CNRS/IN2P3LPCClermont-FerrandFrance Aix marseille Univ CNRS/IN2P3CPPMMarseilleFrance UniversitéParis-Saclay CNRS/IN2P3IJCLabOrsayFrance Laboratoire Leprince-Ringuet CNRS/IN2P3Ecole PolytechniqueInstitut Polytechnique de ParisPalaiseauFrance LPNHE Sorbonne UniversitéParis Diderot Sorbonne Paris CitéCNRS/IN2P3ParisFrance I.Physikalisches Institut RWTH Aachen UniversityAachenGermany Fakultät Physik Technische Universität DortmundDortmundGermany max-Planck-Institut für Kernphysik(mPIK) HeidelbergGermany Physikalisches Institut Ruprecht-Karls-Universität HeidelbergHeidelbergGermany School of Physics University College DublinDublinIreland INFN Sezione di Bari BariItaly INFN Sezione di Bologna BolognaItaly INFN Sezione di Ferrara FerraraItaly INFN Sezione di Firenze FirenzeItaly INFN Laboratori Nazionali di Frascati FrascatiItaly INFN Sezione di Genova GenovaItaly INFN Sezione di milano MilanoItaly INFN Sezione di milano-Bicocca MilanoItaly INFN Sezione di Cagliari MonserratoItaly Universitàdegli Studi di Padova Universitàe INFNPadovaPadovaItaly INFN Sezione di Pisa PisaItaly INFN Sezione di Roma La Sapienza RomaItaly INFN Sezione di Roma Tor Vergata RomaItaly Nikhef National Institute for Subatomic Physics AmsterdamNetherlands Nikhef National Institute for Subatomic Physics and VU University Amsterdam AmsterdamNetherlands AGH-University of Science and Technology Faculty of Physics and Applied Computer Scienc

A first search for the Ξ_(bc)^(+)J/ψΞ_(c)^(+) decay is performed by the LHCb experiment with a data sample of proton-proton collisions, corresponding to an integrated luminosity of 9 fb−1 recorded at centre-of-mass energies of 7, 8, and 13 TeV. Two peaking structures are seen with a local (global) significance of 4.3(2.8) and 4.1(2.4) standard deviations at masses of 6571 and 6694 meV/c2, respectively. Upper limits are set on the Ξ+bc baryon production cross-section times the branching fraction relative to that of the B+c→J/ψd+s decay at centre-of-mass energies of 8 and 13 TeV, in the Ξ+bc and in the B+c rapidity and transverse-momentum ranges from 2.0 to 4.5 and 0 to 20GeV/c, respectively. Upper limits are presented as a function of the Ξ+bc mass and lifetime.

关键词： QCd B physics charm physics spectroscopy

Growth and differentiation factor-11 is developmentally regulated in skeletal muscle and inhibits myoblast differentiation

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Open Journal of molecular and Integrative Physiology 2012年第4期2卷 127-138页

作者： Ferenc Jeanplong Shelley J. Falconer mark Thomas Kenneth G. matthews Jenny m. Oldham Trevor Watson Christopher d. mcmahon AgResearch Ltd. Ruakura Research Centre Hamilton New Zealand

Growth and differentiation factor-11 (GdF-11) is a secreted protein that is closely related to myostatin, a known inhibitor of skeletal muscle development. The role of GdF-11 in regulating skeletal muscle growth remains unclear and the pattern of expression during post-natal growth has not been reported. Therefore, we sought to determine the expression of GdF-11 during post-natal growth and its effect on myoblast proliferation and differentiation. We collected gastrocnemius muscles from male and female mice at 2, 3, 4, 6, 12, 20 and 32 weeks of age (n = 6 per sex and age). In addition, gastrocnemius muscles were col- lected from male wild-type and myostatin knockout mice at 4, 6, 12 and 20 weeks of age (n = 6 per age and genotype). RNA was extracted and reverse tran- scribed. Northern analysis identified an expected 4.4 kb mRNA transcript for GdF-11 in gastrocnemius muscles of mice. The concentration of GdF-11 mRNA, as determined by quantitative PCR, was increased in gastrocnemius muscles from 2 to 6 weeks—a period of rapid postnatal muscle growth—and remained higher in male than female mice from 4 to 20 weeks of age (P gastrocnemius muscles of myostatin knockout compared with wild-type mice (P may suggest a compensatory mecha- nism for the lack of myostatin. In support, recombi- nant GdF-11 inhibited differentiation of C2C12 mur- ine myoblasts and those isolated from myostatin knockout and wild-type mice (P d dif-ferentiation of C2C12 myoblasts was associated with decreased mRNA expression of early and late mo- lecular markers of differentiation (myod, myogenin, IGF-II, desmin and myHC, P dF-11 regulates growth of skeletal muscles by inhibiting myoblast differentiation in an autocrine/paracrine manner and, perhaps, also plays a role in regulating sexually dimorphic growth.

关键词： GdF-11 developmental Expression Post-Natal muscle Growth Sexual dimorphism myoblast differentiation

Critical mechanical properties and FEA simulation for crashworthiness assessment of a coarse-grained cast Am50 alloy

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Journal of magnesium and Alloys 2015年第3期3卷 188-196页

作者： S.Xu C.H.m.Simha m.Gesing J.Liang J.Lo CanmetmATERIALS Natural Resources Canada183 Longwood Rd SHamiltonOntario L8P 0A5Canada

A coarse-grained Am50 alloy was used as a model alloy for investigation of constitutive behaviour,Charpy toughness and effect of stress state on deformation and failure of cast mg *** results provide critical mechanical properties of a cast Am50 alloy for crashworthiness assessment and development of finite element simulation *** cast mg alloys,the effect of strain rate and temperature is larger on tensile strength than on compressive strength because twinning is more extensive in compression than in *** effect of strain rate on compressive strength is negligible because twinning activity of the cast mg alloy is *** load *** of Charpy specimens were measured for modelling,and the effect of loading rate and temperature on load of Charpy specimens is very small because part of the specimen is in *** equivalent strain to fracture of the cylindrical round notched tension specimen decreases with increasing stress triaxiality;though for the flat-grooved plane strain specimen,the equivalent fracture strain remains constant over the range of stress triaxiality *** the two different specimen geometries give rise to different Lode angle values,the test results show that the Lode angle parameter is an important parameter for deformation and fracture of mg *** element simulations of loading of the cylindrical notched-tension and Charpy specimens were carried out using a Lode-angle dependent von mises model,and were found to provide a reasonable description of the load-displacement curves measured in the *** the flat-grooved plane strain specimens,the computations under-predicted the force-displacement response measured.

关键词： Effect of strain rate and temperature Tensile and compressive Crash Simulation Am50

西伯利亚南部和劳伦大陆北部在元古代长期相连

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矿物岩石地球化学通报 2016年第3期35卷 486-486页

作者：夏群科 Ernst R E hamilton m A Soderlund U Hanes J A Gladkochub d P Okrugin A V Kolotilina T mekhonoshin A S Bleeker W LeC heminant A N Buchan K L Chamberlain K R didenko A N

哥伦比亚超大陆（Nuna-Colmbia,17～13亿年）和罗的尼亚超大陆（Rodinia,11～7亿年）的重建一直是地球科学家极感兴趣,也是多年来存在很多争论的科学问题。大火成岩省的分布和特征是古大陆重建的有效途径之一。

关键词：年龄数据地球科学家卡尔顿大学尼亚古地磁岩浆活动金属矿床框架性相互对应

Rationale and design of a randomised double-blind 2×2 factorial trial comparing the effect of a 3-month intensive statin and antiplatelet therapy for patients with acute mild ischaemic stroke or high-risk TIA with intracranial or extracranial atherosclerosis(INSPIRES)

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Stroke & Vascular Neurology 2023年第3期8卷 249-258,I0096-I0110页

作者： Ying Gao Yuesong Pan Shangrong Han Weiqi Chen Jing Jing Chunjuan Wang Yingying Yang Tingting Wang Xia meng Xingquan Zhao Liping Liu Hao Li S Claiborne Johnston Pierre Amarenco Philip m Bath Yongjun Wang Yilong Wang department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijingChina China National Clinical Research Center for Neurological diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina dean's Office Dell Medical SchoolUniversity of Texas at AustinAustinTexasUSA department of Neurology and Stroke Center Assistance Publique-Hôpitaux de Paris(APHP)Bichat HospitalINSERM LVTS-U1148University of ParisParisFrance Population Health Research Institute McMaster UniversityHamiltonOntarioCanada Stroke Trials Unit Mental Health&Clinical NeuroscienceUniversity of NottinghamNottinghamUK Advanced Innovation Center for Human Brain Protection Capital Medical UniversityBeijingChina National Center for Neurological diseases BeijingChina Research Unit of Artificial Intelligence in Cerebrovascular disease Chinese Academy of Medical SciencesBeijingChina Chinese Institute for Brain Research BeijingChina

Background It remains unclear if intensive antiplatelet and statin treatments begun within 24-72 hours of cerebral ischaemic events from intracranial or extracranial atherosclerosis is effective or *** The Intensive Statin and Antiplatelet Therapy for High-risk Intracranial or Extracranial Atherosclerosis(INSPIRES)trial is a randomised,double-blind,placebo-controlled,multicentre and 2×2 factorial trial.6100 individuals between the ages of 35 and 80 who have experienced a mild ischaemic stroke or high-risk transient ischaemic attack(TIA)within the previous 72 hours that is attributed to≥50%atherosclerotic stenosis of a major intracranial or extracranial artery or multiple infarctions of atherosclerotic origin will be enrolled in the *** subjects will be randomised 1:1:1:1 to one of four groups:(1)intensive antiplatelet therapy(combined clopidogrel and aspirin for days 1-21,then aspirin placebo and clopidogrel for days 22-90)plus immediate intensive statin therapy(atorvastatin at a dose of 80 mg daily for the first 21 days,then 40 mg daily for days 22-90);(2)intensive antiplatelet therapy plus delayed intensive statin therapy(atorvastatin placebo for days 1-3,followed by 40 mg per day of atorvastatin for days 4-90);(3)standard antiplatelet therapy(combination of clopidogrel placebo with aspirin for 90 days)plus immediate intensive statin therapy and(4)standard antiplatelet therapy plus delayed intensive statin *** primary efficacy endpoint is any new stroke(ischaemic or haemorrhagic)within 90 days after *** primary safety endpoint is moderate to severe bleeding at 90 *** The INSPIRES trial will assess the efficacy and safety of intensive antiplatelet therapy and immediate intensive statin therapy begun within 72 hours of onset in decreasing the recurrent stroke at 90 days in patients with acute mild ischaemic stroke or high-risk TIA of intracranial or extracranial atherosclerosis origin.

关键词： intracranial atherosclerosis random

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早期发生的严重糖尿病相关性微血管并发症

世界核心医学期刊文摘（儿科学分册） 2005年第2期1卷 41-41页

作者： hamilton J. Brown m. Silver R. daneman d. 贺莉 dr.division of EndocrinologyHospital for Sick Children555 University Ave TorontoOnt.M5G 1X8Canada

1例患有1型糖尿病的16岁女孩,虽然血糖控制得很好,但在1个月内发展成疼痛性外周神经疾病,1年内发展成增生性视网膜病。

关键词：增生性视网膜病疼痛性外周神经