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Incorporation of Omega-3 on an Extruded Snack with Golden Flaxseed

Journal of Food Science and Engineering 2013年第6期3卷 317-322页

作者： Amira F. Kessler Annahas Damila R. de morais Breno m. Joia Ana C. de Aguiarl, Jesui V. Visentainer Antonio R. Giriboni monteiro Department of Food Engineering State University of Maringa Maringá Paran6 87020-900 Brazil Department of Chemistry State University of Maringa Maringá Paraná 87020-900 Brazil

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中能区64Zn+27Al反应中集体流的实验研究

中能区64Zn+27Al反应中集体流的实验研究

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第九届全国核物理大会

作者：贺智勇 J.Peter J.C.Angelique A.Auger G.Bizard R.Brou A.Buta C.Cabot E.Crema D.Cussol Y.El masri Ph.Eudes m.Gonin K.Hagel A.Kerambrum C.Lebrun A.Peghaire R.Popescu R.Regimbart E.Rosato F.Saint-laurent J.C,Steckmeyer B.Tamain E.Vient R.Wada 中国科学院近代物理研究所 LPC Caen ISMRAIN2P3—CNRS14050 CAEN CEDEXFRANCE GANIL BP5027 14021 CAEN CEDEXFRANCE Institut de Physique Nuclear UCL1348 Louvain—La—NeuveBELGIUM LPN Universite de Nantes44072 NANTES CEDEXFRANCE Cyclotron Institut Texas A&M UniversityCollege StationTX77843USA

核物质集体流的研究是重离子碰撞中很重要的一个研究课题,通过它可以探讨核物质状态方程．压缩效应和重离子碰撞动力学等．最近,我们在中能区观察到了集体流及其消失,买验是在法国 GANIL 加速器上进行的,用49,57,69和79 meV/u 的“Zn ...

核物质集体流的研究是重离子碰撞中很重要的一个研究课题,通过它可以探讨核物质状态方程．压缩效应和重离子碰撞动力学等．最近,我们在中能区观察到了集体流及其消失,买验是在法国 GANIL 加速器上进行的,用49,57,69和79 meV/u 的“Zn 束轰击Al 靶．前角3°至30°间粒子的探测由96块塑料闪烁体片组成的塑闪墙完成,塑闪墙分七环,靶距210cm．中后角30°至150°间

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病态肥胖外科治疗术前对非酒精性脂肪性肝炎的检测:声脉冲辐射力成像技术的初步研究

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国际医学放射学杂志 2013年第1期 90-90页

作者： F.Guzmán-Aroca m.D.Frutos-Bernal A.Bas J.A.Luján-mompeán m.Reus J.de Dios Berná-Serna 程悦 Department of of Radiology Virgen de la Arrixaca University Hospital30120 El PalmarMurciaSpain

目的在肥胖症治疗术前,采用声脉冲辐射力成像(ARFI)通过测定剪切波速度(SWV)技术,评价鉴别非酒精性脂肪肝(NAFLD)与非酒精性脂肪性肝炎(NASH)的能力。方法 32例肥胖症病人术前进行ARFI和常规超声检查。以肝脏活检结果为标准,并与ARFI和... 详细信息

目的在肥胖症治疗术前,采用声脉冲辐射力成像(ARFI)通过测定剪切波速度(SWV)技术,评价鉴别非酒精性脂肪肝(NAFLD)与非酒精性脂肪性肝炎(NASH)的能力。方法 32例肥胖症病人术前进行ARFI和常规超声检查。以肝脏活检结果为标准,并与ARFI和超声结果进行比较。根据组织学结果将病人分为3组:A组,单纯脂肪变性;B组,炎性改变;C组,纤维化。结果 SWV值的中位数为(1.57±0.79)m/s。所有病人的组织病理学检查均发现存在肝脏异常改变病变(100%),包括实验室检查正常者。A、B、C3组间的SWV值存在统计学差异,分别为(1.34±0.90)m/s、(1.55±0.79)m/s和(1.86±0.75)m/s(Pm/s,敏感度85%,特异度83.3%)。结论在无症状的肥胖症病人中,ARFI技术是鉴别NAFLD与NASH的有效诊断工具。

关键词：非酒精性脂肪性肝肥胖症病人肥胖病 NAFLD 术前

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白塞病合并周围神经病变(法国)

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世界核心医学期刊文摘（神经病学分册） 2005年第8期1卷 8-8页

作者： Ben Ghorbel I. Ibnelhadj Z. Zouari m. 方伯言 Service de médecine Interne Hpital La Rabta 1007 Tunis Tunisia

Introduction. The involvement of the peripheral nervous system in Behet’s d isease is very rare. Case report. We report a case of a 47-year-old man with a six-year history of Behet’s disease and a two-year history of peripheral n ervous system involvement. This patient presented with paraesthesia and weakness of the upper and lower limbs, diarrhea and erectile dysfunction. The electromyo gram showed evidence of an axonal sensorimotor neuropathy and the nerve biopsy s howed an axonal neuropathy. Routine blood tests were normal, there was no increa se of serum creatine kinase, aspartate aminotransfease or lactate dehydrogenase and no signs of hyperthyroidism. Fibroscopy and colonoscopy showed no signs of e ntero-Beh*** patient was treated with prednisone, cyclophosphamide and car bamazepine with an improvement of paraesthesia. Conclusion. The mechanism of the peripheral neuropathy in Behet’s disease is still unknown, it might be due t o vasculitis of the vasa nervorum or to the side effects of colchicine. Our repo rt is particular by the association of sensorimotor and autonomic involvement of peripheral neuropathy in a patient with Behet’s disease.

关键词：白塞病神经活检肌电图检查神经滋养血管感觉异常结肠镜检查勃起功能障碍肌无力乳酸脱氢酶轴索

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具有转移灶的原发性黑素瘤退化伴肌发育不全性皮肌炎(法语)

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世界核心医学期刊文摘（皮肤病学分册） 2006年第11期2卷 40-40页

作者： Villers A. lami m.-C. Filoche P. 李晓莉 Service de Dermatologie CHU de Poitiers 2 rue de la Milétrie 86021 Poitiers Cedex

Background. Dermatomyositis is a rare and serious inflammatory connective tissue disease characterized by a typical cutaneous rash and myopathy. Amyopathic dermatomyositis is a particular form of dermatomyositis involving only cutaneous signs and without myopathy present for over 2 years. Patients and methods. A 48 year-old woman presented with a 3-year history of cutaneous rash without myopathy characteristic of amyopathic dermatomyositis. Clinical examination revealed extensive axillary adenopathy, histological examination of which suggested secondary melanoma. The patient reported a black nevus in the axillary area that had disappeared 1 year earlier. Curettage of the lymph node was negative and the patient was treated with interferon (3m 3 times a week)-. Regression of the cutaneous signs was noted. Discussion. The data, there have been no other reports of paraneoplastic amyopathic dermatomyositis associated with regression of primary melanoma. The literature contains few reports of dermatomyositis associated with melanoma. Amyopathic dermatomyositis may be associated with malignancy.

关键词：黑素瘤皮肌炎发育不全腋窝淋巴结组织学检查结缔组织病皮肤症状肌病肌皮

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宫颈癌盆腔淋巴结切除术:腹膜外与腹腔镜两种术式的对比研究

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世界核心医学期刊文摘（妇产科学分册） 2006年第12期2卷 16-16页

作者： larciprete G. Casalino B. Segatore m.F. 张新艳 Associazione Fatebenefratelli per la Ricerca (A.Fa.R.) Department of Obstetrics and GynecologyFatebenefratelli Isola Tiberina HospitalP.zza Fatebenefratelli 3900186 RomeItaly

Objective:To compare the extraperitoneal versus the laparoscopic technique in performing pelvic lymphadenectomy in a series of patients undergoing a radical vaginal hysterectomy for locally advanced cervical cancer. Study design:Retrospective study with 42 patients undergoing a radical vaginal hysterectomy for cervical cancer. Patients from group A (20 patients) had a laparoscopic lymph node dissection and patients belonging to group B (22 patients) had an extraperitoneal lymphadenectomy. Historical data,clinical and surgical characteristics,perioperative and post-operative complications were analyzed. Follow-up was conducted according to the oncologic requirements. Results:No significant difference was observed between the two groups in terms of blood loss,post-operative pain,transfusions,hospital stay and post-operative hematomas. The extraperitoneal group (group B) significantly showed a reduced operating time,a greater number of nodes removed (p mphocyst occurred in group B. Conclusions:Extraperitoneal pelvic lymphadenectomy can be considered an adequate technique to complement radical vaginal operations for cervical cancer.

关键词：盆腔淋巴结腹膜外切除术腔镜晚期宫颈癌淋巴囊肿手术时间根治性手术手术特点术后疼痛

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左室收缩功能障碍所致心衰:出院及出院1年时的治疗

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世界核心医学期刊文摘（心脏病学分册） 2006年第1期2卷 58-58页

作者： Houpe D. Peltier m. Cohen-Solal A. C. Tribouilloy 杜媛 Service de Cardiologie B Groupe Hospitalier Sud Avenue RenéLannec 80 054 Amiens Cédex 1 France

Background: The treatment of heart failure(HF) due to left ventricular systolic dysfunction has been defined in recent guidelines, but these guidelines are not always applied in routine clinical practice. One of the objectives of the ETICS study was to evaluate medical treatment at discharge and after 1 year in patients hospitalised for a first episode of congestive HF due to left ventricular systolic dysfunction in 2000. methods: One hundred and seventy nine patients(63%males, mean age of 69±13 years) with an ejection fraction ≤40%were prospectively included. The main aetiology was ischaemic heart disease(44%). Results: The drugs prescribed at discharge and at one year, respectively, were loop diuretics in 95%and 91%of cases, angiotensin-converting enzyme(ACE) inhibitors in 82%and 75%, spironolactone in 35%and 37%, beta-blockers in 25%and 41%, digitalis glycosides in 34%and 30%of cases, and nitrates in 20%and 16%of cases. ACE inhibitors were prescribed at discharge and at 1 year at dosages reaching 64±29%and 72±30%of the recommended doses, respectively, and beta-blockers were prescribed at 26±16%and 35±25%of recommended doses, respectively. Conclusion: Diuretics and ACE inhibitors are largely prescribed in HF due to left ventricular systolic dysfunction, followed by spironolactone. Beta-blockers are still underused both in terms of the rate of patients receiving them and the daily doses. These results highlight the value of continuing to widely circulate official practice guidelines in order to improve the management of HF due to left ventricular systolic dysfunction.

关键词：左室收缩功能障碍临床治疗出院时心衰缺血性心脏病髓袢利尿药治疗情况射血分数平均年龄处方药物

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阴茎硬化萎缩性苔癣与致癌性人类乳头瘤病毒感染的相关性

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世界核心医学期刊文摘（皮肤病学分册） 2006年第10期2卷 52-52页

作者： Nasca m.R. Innocenzi D. micali G. 吴佳纹 Dermatology Clinic University of CataniaPiazza S.Agata La Vetere 695124 CataniaItaly

Background:Data on the prevalence of human papillomavirus(HPV)infection in patients with penile lichen sclerosus(LS)-are scant and ***:To investigate the prevalence of HPV infections in patients with penile ***:HPV infection was assessed by polymerase chain reaction(PCR)-in paraffin-embedded penile biopsies obtained from the glans or inner foreskin of 46 adult patients with penile LS,and in brush cytology smears of penile healthy mucosa from an equal number of randomly selected control males matched for *** evaluation was performed using conditional logistic regression ***:PCR disclosed the presence of HPV infection in17.4%of LS patients(HPV 16,six cases;HPV 18,one case;HPV 45,one case).Amongst the controls,HPV infection occurred in 8.7%of patients(HPV 16,two cases;HPV 53,one case;HPV 70,one case).Statistical regression analysis confirmed that the rate of HPV infection was higher amongst patients with genital LS than amongst healthy controls [odds ratio(OR),2.55;95%confidence interval(CI),0.73-8.89].Conclusions:Infection with oncogenic “high-risk”HPV types in patients with genital LS may enhance the risk of penile cancer arising on LS.

关键词：致癌性阴茎癌人乳头状瘤病毒细胞学涂片聚合酶链反应正常男性对数回归阴茎部活检标本统计

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乙型肝炎病毒的基因型和肝外表现

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世界核心医学期刊文摘（胃肠病学分册） 2006年第3期2卷 59-59页

作者： Cacoub P. Saadoun D. Bourlière m. 李宏宇 Department of Internal medicine Hpital La Pitié-Salpêtrière. 83 Boulevard de l'Hpital 75651 Paris Cedex 13 France

Background/Aims: This study aimed at correlating the presence of extrahepatic manifestations with hepatitis B virus (HBV) genotypes in patients with chronic HBV infection. methods: This was a national (France), multicenter, retrospective, cross-sectional study. HBV genotypes were determined in 190 patients HBsAg-positive for at least 6 months and documented before any treatment. Results: Patients were aged 42±15 years and mainly male (77%). Alcohol intake was high in 6%of them, ALT elevated in 73%; 27%were cirrhotic. All HBV genotypes were found, mainly A (24%), D (29%), C (11%), and E (10%). Thirty (16%) patients had clinical extrahepatic manifestations, mainly sensory-motor deficiency, sicca syndrome, myalgia, glomerulonephritis, and arthralgia-arthritis. Their presence was not related to any epidemiologic, viral (including genotypes) or hepatic factor, but to a higher platelet count (P=0.004). Twenty-nine (15%) patients had biological extrahepatic manifestations, mainly anti-smooth muscle, antinuclear, and anti-nucleo-some antibodies. Their presence was related only to anti-HBe antibodies positivity (P=0.007) or elevated platelet count (P=0.003). Carrying precore mutant HBV increased by 2.8 folds the risk to have at least one extrahepatic biological manifestation. Conclusions: No relationships between HBV genotypes and the presence of extrahepatic manifestations were evidenced in patients with chronic HBV infection.

关键词：乙型肝炎病毒基因分型抗平滑肌抗体干燥综合征抗核小体抗体肾小球肾炎关节痛抗核抗体肌痛

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脑胶质瘤的初始化疗

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世界核心医学期刊文摘（神经病学分册） 2005年第1期1卷 34-34页

作者： Sanson m. Cartalat-Carel S. Taillibert S. 陈云春 Federation de Neurologie mazarin Hopital de la Salpetriere 47Bd de l’ Hpital 75013Paris France Dr.

Background: Because of the diffuse nature of gliomatosis cerebri (GC), surgery is not suitable, and large field radiotherapy carries the risk of severe toxicity. In this setting, initial chemotherapy warrants further investigation. methods: The authors treated 63 consecutive patients with GC with initial chemotherapy consisting of either PCV (procarbazine, 60 mg/m2 on days 8 to 21; CCNU, 110 mg/m2 on day 1; and vincristine, 1.4 mg/m 2 on days 8 and 29) or temozolomide (TmZ; 150 to 200 mg/m2 for 5 days every 4 weeks). There were 40 men and 23 women, with a median age of 48 years (range, 17 to 74 years) and a median Karnofsky performance status of 90 (range, 50 to 100). GC was initially present at diagnosis in 49 patients (primary GC), whereas 14 patients with a circumscribed glioma at onset developed secondary GC after a median follow up period of 5.11 years. GC was classified based on the predominant tumor cells as astrocytic, oligodendroglial, or mixed GC. Results: Seventeen patients received 1 to 6 cycles (median, 5) of PCV, and 46 received 2 to 24 courses (median, 13) of TmZ. Grade 3 to 4 hematologic toxicity was seen in 4 of 17 (23.5% ) patients treated with PCV and in 4 of 46 (8.6% ) of those treated with TmZ. Clinical objective responses were observed in 21 of 63 (33% ) patients, and radiologic responses were seen in 16 of 62 (26% ), with no significant difference between the two regimens. For all patients combined, the median progression free survival (PFS) and overall survival (OS) were 16 months and 29 months, respectively. Regardless of the chemotherapeutic regimen, oligodendroglial GC had a better prognosis than astrocytic and oligoastrocytic GC in terms of PFS (p motherapy is useful for some patients with gliomatosis cerebri. Temozolomide is well tolerated and appears to be a valuable alternative to procarbazine CCNU vincristine, especially for those with slow growing, low grade GC.

关键词：初始化疗脑胶质瘤替莫唑胺少突胶质细胞瘤星形胶质细胞瘤甲基苄肼 vincristine 系统毒性中位随访期化疗方法

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