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Design of a large-scale model for wind tunnel test of a multiadaptive flap concept

Chinese Journal of Aeronautics 2024年第2期37卷 58-80页

作者： mürüvvet Sinem SICIm DEmIRCI Rosario PECORA metin Orhan KAYA Aeronautical Engineering Department Istanbul Technical UniversityIstanbulTurkey Industrial Engineering Department University of Naples Federico IINapoliItaly

The design and application of morphing systems are ongoing issues compelling the aviation *** Clean Sky-program represents the most significant aeronautical research ever launched in Europe on advanced technologies for greening next-generation *** primary purpose of the program is to develop new concepts aimed at decreasing the effects of aviation on the environment,increasing reliability,and promoting eco-friendly *** ambitions are pursued through research on enabling technologies fostering noise and gas emissions reduction,mainly by improving aircraft aerodynamic *** the Clean Sky framework,a multimodal morphing flap device was designed based on tight industrial requirements and tailored for large civil aircraft *** flap is deployed in one unique setting,and its cross section is morphed differently in take-off and landing to get the necessary extra lift for the specific flight ***,during the cruise,the tip of the flap is deflected for load control and induced drag *** manufacturing the first flap prototype,a high-speed(ma=0.3),large-scale test campaign(geometric scale factor 1:3)was deemed necessary to validate the performance improvements brought by this novel system at the aircraft *** the other hand,the geometrical scaling of the flap prototype was considered impracticable due to the unscalability of the embedded mechanisms and actuators for shape ***,a new architecture was conceived for the flap model to comply with the scaled dimensions requirements,withstand the relevant loads expected during the wind tunnel tests and emulate the shape transition capabilities of the true-scale *** strategies were developed to effectively morph the model during wind tunnel tests while ensuring the robustness of each morphed configuration and maintaining adequate stiffness levels to prevent undesirable deviations from the intended aerodynamic ***,

关键词： morphing structures Smart aircraft morphing flap Adaptive systems Finger-like ribs Wind tunnel tests Large-scale morphing archi-tectures Variable camber airfoil

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Artificial Intelligence Prediction of One-Part Geopolymer Compressive Strength for Sustainable Concrete

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Computer modeling in Engineering & Sciences 2024年第10期141卷 525-543页

作者： mohamed Abdel-mongy mudassir Iqbal m.Farag Ahmed.m.Yosri Fahad Alsharari Saif Eldeen A.S.Yousef Department of Civil Engineering College of EngineeringJouf UniversitySakaka72388Saudi Arabia Department of Civil Engineering University of Engineering and TechnologyPeshawar54890Pakistan Civil Engineering Department Faculty of EngineeringAl-Azhar UniversityCairo11884Egypt Civil Engineering Department Faculty of EngineeringAswan UniversityAswan81528Egypt

Alkali-activated materials/geopolymer(AAms),due to their low carbon emission content,have been the focus of recent studies on ecological *** terms of performance,fly ash and slag are preferredmaterials for precursors for developing a one-part ***,determining the optimum content of the input parameters to obtain adequate performance is quite challenging and scarcely ***,in this study,machine learning methods such as artificial neural networks(ANN)and gene expression programming(GEP)models were developed usingmATLAB and GeneXprotools,respectively,for the prediction of compressive strength under variable input materials and content for fly ash and slag-based one-part *** database for this study contains 171 points extracted from literature with input parameters:fly ash concentration,slag content,calcium hydroxide content,sodium oxide dose,water binder ratio,and curing *** performance of the two models was evaluated under various statistical indices,namely correlation coefficient(R),mean absolute error(mAE),and rootmean square error(RmSE).In terms of the strength prediction efficacy of a one-part geopolymer,ANN outperformed *** and parametric analysis were also performed to identify the significant contributor to *** to a sensitivity analysis,the activator and slag contents had the most effects on the compressive strength at 28 *** water binder ratio was shown to be directly connected to activator percentage,slag percentage,and calcium hydroxide percentage and inversely related to compressive strength at 28 days and curing temperature.

关键词： Artificial intelligence techniques one-part geopolymer artificial neural network gene expression modelling sustainable construction polymers

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Intelligent Fractional-Order Controller for SmES Systems in Renewable Energy-Based microgrid

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Computer modeling in Engineering & Sciences 2024年第8期140卷 1807-1830页

作者： Aadel m.Alatwi Abualkasim Bakeer Sherif A.Zaid Ibrahem E.Atawi Hani Albalawi Ahmed m.Kassem Electrical Engineering Department Faculty of EngineeringUniversity of TabukTabuk47913Saudi Arabia Industrial Innovation and Robotic Center(IIRC) University of TabukTabuk47731Saudi Arabia Department of Electrical Engineering Faculty of EngineeringAswan UniversityAswan81542Egypt Renewable Energy and Environmental Technology Centre University of TabukTabuk47913Saudi Arabia Electrical Engineering Department Faculty of EngineeringSohag UniversitySohag82524Egypt

An autonomous microgrid that runs on renewable energy sources is presented in this *** has a supercon-ducting magnetic energy storage(SmES)device,wind energy-producing devices,and an energy storage ***,because such microgrids are nonlinear and the energy they create varies with time,controlling and managing the energy inside them is a difficult ***-order proportional integral(FOPI)controller is recommended for the current research to enhance a standalone microgrid’s energy management and *** suggested dedicated control for the SmES comprises two loops:the outer loop,which uses the FOPI to regulate the DC-link voltage,and the inner loop,responsible for regulating the SmES current,is constructed using the intelligent FOPI(iFOPI).The FOPI+iFOPI parameters are best developed using the dandelion optimizer(DO)approach to achieve the optimum *** suggested FOPI+iFOPI controller’s performance is contrasted with a conventional PI controller for variations in wind speed and microgrid *** optimal FOPI+iFOPI controller manages the voltage and frequency of the *** behavior of the microgrid as a reaction to step changes in load and wind speed was measured using the proposed *** simulations were used to evaluate the recommended system’s *** results of the simulations showed that throughout all interruptions,the recommended microgrid provided the load with AC power with a constant amplitude and *** addition,the required load demand was accurately ***,the microgrid functioned incredibly well despite SmES and varying wind *** obtained under identical conditions were compared with and without the best FOPI+iFOPI *** utilizing the optimal FOPI+iFOPI controller with SmES,it was found that the microgrid performed better than the microgrid without SmES.

关键词： Fractional-order proportional integral(FOPI) intelligent controller renewable energy resources superconducting magnetic energy storage optimization

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Assessment of plant diversity of endemic species of the Saharo-Arabian region in Egypt

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Journal of Arid Land 2024年第7期16卷 1000-1021,I0002-I0044页

作者： Asmaa S ABO HATAB Yassin m AL-SODANY Kamal H SHALTOUT Soliman A HAROUN mohamed m EL-KHALAFY Botany and microbiology Department Faculty of ScienceKafrelsheikh UniversityKafrelsheikh 33511Egypt Botany Department Faculty of ScienceTanta UniversityTanta 31527Egypt

Savanna, semi-deserts, and hot deserts characterize the Saharo-Arabian region, which includes morocco, mauretania, Algeria, Tunisia, Libya, Egypt, Palestine, Kuwait, Saudi Arabia, Qatar, Bahrain, the United Arab Emirates, Oman, Yemen, southern Jordan, Syria, Iraq, Iran, Afghanistan, Pakistan, and northern India. Its neighboring regions, the Sudano-Zambezian region belonging to the Paleotropical Kingdom and the mediterranean and Irano-Turanian regions included in the Holarctic Kingdom, share a large portion of their flora with the Saharo-Arabian region. Despite the widespread acknowledgment of the region's global importance for plant diversity, an up to date list of the Saharo-Arabian endemics is still unavailable. The available data are frequently insufficient or out of date at both the whole global and the national scales. Therefore, the present study aims at screening and verifying the Saharo-Arabian endemic plants and determining the phytogeographical distribution of these taxa in the Egyptian flora. Hence, a preliminary list of 429 Saharo-Arabian endemic plants in Egypt was compiled from the available literature. Indeed, by excluding the species that were recorded in any countries or regions outside the Saharo-Arabian region based on different literature, database reviews, and websites, the present study has reduced this number to 126 taxa belonging to 87 genera and 37 families. Regarding the national geographic distribution, South Sinai is the richest region with 83 endemic species compared with other eight phytogeographic regions in Egypt, followed by the Isthmic Desert(the middle of Sinai Peninsula, 53 taxa). Sahara regional subzone(SS1) distributes all the 126 endemic species, Arabian regional subzone(SS2) owns 79 taxa, and Nubo-Sindian subzone(SS3) distributes only 14 endemics. Seven groups were recognized at the fourth level of classification as a result of the application of the two-way indicator species analysis(TWINSPAN) to the Saharo-Arabian endemic sp

关键词： endemism phytogeographical regions Saharo-Arabian floristic region Egyptian flora plant diversity two-way indicator species analysis(TWINSPAN)

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Poly(A)-specific RNase(PARN)generates and regulates miR-125a-5p 3’-isoforms,displaying an altered expression in breast cancer

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Signal Transduction and Targeted Therapy 2024年第5期9卷 1805-1807页

作者： Luisa Tomasello Shoshanah m.Holub Giovanni Nigita Rosario Distefano Carlo m.Croce Department of Cancer Biology and Genetics The Ohio State UniversityColumbusOHUSA Department of Internal medicine Division of HematologyThe Ohio State UniversityColumbusOHUSA

Dear Editor,microRNAs(miRNAs)are small non-coding RNAs crucial for post-transcriptional gene regulation,processed from primary miRNA transcripts by Drosha and Dicer.1 Latest advancements in Next Generation Sequencing highlighted the existence of miRNA isoforms(isomiRs)resulting from alternative processing,RNA editing,or post-transcriptional modifications.

关键词： breast cancer advancement

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Effect of solidification cooling rate on microstructure and tribology characteristics of Zn-4Si alloy

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International Journal of minerals,metallurgy and materials 2024年第2期31卷 362-373页

作者： F.Akbari m.Golkaram S.Beyrami G.Shirazi K.mantashloo R.Taghiabadi m.Saghafi Yazdi I.Ansarian Department of metallurgy and material Science Imam Khomeini International University(IKIU)Qazvin ***Iran

The main objective of this work was to modify the microstructure and enhance the tribological properties of a new Zn-4Si al-loy through a high solidification cooling rate(SCR).According to the results,by increasing the SCR from 2.0 to 59.5℃/s the average size of primary Si particles and that of the grains reduced from 76.1 and 3780μm to less than about 14.6 and 460μm,***-ing the SCR also enhanced the microstructural homogeneity,decreased the porosity content(by 50%),and increased the matrix hardness(by 36%).These microstructural changes enhanced the tribological *** instance,under the applied pressure of 0.5 mPa,an in-crease in the SCR from 2.0 to 59.5℃/s decreased the wear rate and the average friction coefficient of the alloy by 57%and 23%,*** wear mechanism was also changed from the severe delamination,adhesion,and abrasion in the slowly-cooled alloy to the mild tribolayer delamination/abrasion in the high-cooling-rate-solidified sample.

关键词： zinc-silicon alloy primary silicon solidification cooling rate tribology sliding wear

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Neuroprotective effect of liraglutide and memantine in a rat model of Alzheimer’s disease

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Asian Pacific Journal of Tropical Biomedicine 2024年第5期14卷 207-214页

作者： Duaa m.Bakhshwin Foziya W.Alhalabi mohamad Omar Barasheed Ahmed m.Bakhshwin maha H.Jamal mohammed A.Bazuhair Fatemah O.Kamel Rania m.magadmi Zoheir A Damanhouri Samar m.Alsaggaf Department of Clinical Pharmacology Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia Hera General Hospital MakkahSaudi Arabia Department of Pathology Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia Department of Clinical Anatomy Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia

Objective:To assess the effect of memantine combined with liraglutide on aluminum chloride(AlCl_(3))and D-galactose(D-GAL)-induced neurotoxicity in ***:male Wistar rats were divided into 5 groups of 5 animals each:the positive control,the negative control,the memantine-treated group,the liraglutide-treated group,and the combination group treated with memantine and ***_(3)and D-GAL were used to induce *** tests,brain beta-amyloid protein,and oxidative stress biomarkers were ***:The morris water maze test indicated an enhanced memory in the combination ***,the combination treatment of liraglutide and memantine resulted in a remarkable reduction in the beta-amyloid protein level in the brain *** inflammation and oxidative stress biomarkers were significantly reduced,and the levels of antioxidant parameters were ***:The combination of liraglutide and memantine exerts neuroprotective effects and enhances memory and cognitive functions in rats with Alzheimer’s disease.

关键词： Alzheimer’s disease Cognitive function Glucagonlike peptide-1 Liraglutide memantine

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monogenic diabetes in children:An underdiagnosed and poorly managed clinical dilemma

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World Journal of Diabetes 2024年第6期15卷 1051-1059页

作者： Saptarshi Bhattacharya Joseph m Pappachan Department of Endocrinology Indraprastha Apollo HospitalsDelhi 110076India Department of Endocrinology and metabolism Lancashire Teaching Hospitals NHS TrustPreston PR29HTUnited Kingdom Faculty of Science Manchester Metropolitan UniversityManchester M156BHUnited Kingdom Faculty of Biology Medicine and HealthThe University of ManchesterManchester M139PLUnited Kingdom

monogenic diabetes,constituting 1%-2%of global diabetes cases,arises from single gene defects with distinctive inheritance *** over 50 associated genetic disorders,accurate diagnoses and management of monogenic diabetes remain inadequate,underscoring insufficient clinician *** disease spectrum encompasses maturity-onset diabetes of the young(mODY),characterized by distinct genetic mutations affecting insulin secretion,and neonatal diabetes mellitus(NDm)-a heterogeneous group of severe hyperglycemic disorders in *** diabetes,autoimmune monogenic diabetes,genetic insulin resistance and lipodystrophy syndromes further diversify the monogenic diabetes landscape.A tailored approach based on phenotypic and biochemical factors to identify candidates for genetic screening is recommended for suspected cases of *** diagnosis warrants immediate molecular genetic testing for infants under six *** these genetic defects presents a unique opportunity for precision *** research aimed to develop cost-effective genetic testing methods and gene-based therapy can facilitate appropriate identification and optimize clinical *** and study of new genes offer a valuable opportunity to gain deeper insights into pancreatic cell biology and the pathogenic mechanisms underlying common forms of *** clinical review published in the recent issue of World Journal of Diabetes is such an attempt to fill-in our knowledge gap about this enigmatic disease.

关键词： monogenic diabetes maturity-onset diabetes of the young Neonatal diabetes mitochondrial diabetes Insulin resistance syndromes Genetic testing Next generation sequencing

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Overcoming geographical and socioeconomic limitations in colorectal cancer screening

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 1683-1689页

作者： Sofia Rozani Panagis m Lykoudis School of medicine National and Kapodistrian University of AthensAthens 11527Greece Division of Surgery and Interventional Science University College LondonLondon WC1E 6BTUnited Kingdom

Despite colorectal cancer’s(CRC)high global incidence,residents of low-and middle-income countries,as well as low-income minorities in advanced economies have low screening *** studies demonstrate that in these groups higher incidence of CRC is observed,yet screening rates remain low for consistent *** income,low educational background,and lack of awareness in combination with inadequate social security of certain population groups impede access and compliance rates to CRC *** the other hand,despite the global availability of multiple screening approaches(colonoscopy,sigmoidoscopy,faecal occult blood test,faecal immunochemical test,computed tomography-colonography,etc.)with proven diagnostic validity,many low-income countries still lack established screening *** absence of screening guidelines in these countries along with the heterogeneity of guidelines in the rest of the world,demonstrate the need for global measures to tackle this issue *** essential step forward is to develop a global approach that will link specific elements of screening with the incidence and available resources in each country,to ensure the achievement of at least a minimum screening program in low-income *** cheaper,cost-effective techniques,which can be carried out by less specialized healthcare providers,might not be equivalent to endoscopy for CRC screening but seems more realistic for areas with fewer *** has been highlighted as the most pivotal element for the effective implementation of any screening program concerning ***,multiple studies have demonstrated that outreach strategies and community-based educational programs are associated with encouraging outcomes,yet a centrally coordinated expansion of these programs could provide more consistent ***,patient navigator programs,wherever implemented,have increased CRC screening and improved ***,global coordin

关键词： Colorectal cancer Screening Low-and middle-income countries Socioeconomic disparities Cancer

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mechanisms behind the environmental sensitivity of carbon fiber reinforced polytetrafluoroethylene(PTFE)

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Friction 2024年第5期12卷 997-1015页

作者： Pontus JOHANSSON P.mARKLUND m.BJORLING Y.SHI Division of machine Element LuleåUniversity of TechnologyLuleåSE-97187Sweden

Carbon fiber reinforced polytetrafluoroethylene (CF/PTFE) composites are known for their exceptional tribological performance when sliding against steel or cast iron in inert gas environments. Compared to experiments in humid air, about an order of magnitude lower wear rate and several times lower coefficient of friction have been reported for tests conducted in dry nitrogen and hydrogen. moreover, trace moisture has been shown to affect the friction and wear significantly of this tribosystem, although a possible effect of oxygen cannot be ruled out due to uncertainties regarding the oxygen concentrations. While several studies have pointed out the environmental sensitivity of CF/PTFE, the understanding of the underlying mechanisms are very limited. The objective of this research is to investigate the individual and combined effect of oxygen and moisture on the tribological behavior of CF/PTFE sliding against steel. Additionally, this study aims to elucidate the underlying mechanisms that govern the environmental sensitivity of the system. Climate-controlled three-pin-on-disc experiments were conducted in nitrogen atmospheres at various concentrations of oxygen and moisture. The tribological results clearly demonstrate that both moisture and oxygen contribute to increased friction and wear. However, the adverse effect was much more pronounced for oxygen than moisture. A qualitative method was developed to estimate the tribofilm coverage on the CF/PTFE surface. Results showed strong correlation between high coverage of strongly adhered tribofilm and low wear rate. moreover, a loosely adhered tribofilm was observed on top of the CF/PTFE surface in presence of moisture. FTIR analysis indicated that the loosely adhered tribofilm found in the moisture-enriched environment contained a significant amount of adsorbed water, which may explain the lower coefficient of friction in presence of moisture compared to oxygen. The adsorbed water in the loosely adhered tribofilm coul

关键词： polymer composite tribofilm tribochemistry atmosphere

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