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Ultraviolet humic-like component contributes to riverine dissolved organic matter biodegradation

Journal of Environmental Sciences 2023年第2期124卷 165-175页

作者： maofei ni Siyue Li College of Eco-Environmental Engineering Guizhou Minzu UniversityGuiyang 550025China Research Center for Environmental Ecology and Engineering School of Environmental Ecology and Biological EngineeringWuhan Institute of TechnologyWuhan 430205China The karst environmental geological hazard prevention laboratory of Guizhou minzu University Guiyang 550025China Key Laboratory of Reservoir Aquatic Environment Research Center for EcohydrologyChongqing Institute of Green and Intelligent TechnologyChinese Academy of SciencesChongqing 400714China

Biological degradation of dissolved organic matter(DOm)regulates its structure and fate in river *** views suggested that labile components were dominantly consumed by microbial *** we provide new observations that a part of recalcitrant compounds largely contribute to riverine DOm *** excitationemission matrix fluorescent spectroscopy combined with peak picking and parallel factor analysis are used to explore component variability during DOm ***-like and tryptophan-like DOm are the primary components of riverine DOm,with proportion contributions of 39%–82% and 16%–61% for % of the maximumfluorescence intensity,*** 56 days of aerobic incubation in the dark,large amounts of tyrosine-like DOm generation are *** temperature enhances the decomposition of ultraviolet humiclike substance and further stimulates labile DOm bio-mineralization into carbon ***,averaged proportions of amino acid compositions(peak B and T)markedly increase(pmic-like compositions(peak A,m and C)decrease after DOm incubation,suggesting incomplete degradation of refractory DOm from high-molecular to low-molecular weight *** findings support the new notion of the continuous DOm biodegradation in a mode as“steps by steps”,contributing to a new understanding of carbon cycling for the UN Sustainable Development Goal.

关键词： Dissolved organic matter(DOm) Sequential biodegradation Recalcitrant compounds Component and fate Fluorescence analysis

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mitochondria–cGAS–STING axis is a potential therapeutic target for senescence-dependent inflammaging-associated neurodegeneration

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Neural Regeneration Research 2025年第3期20卷 805-807页

作者： Josém.Izquierdo Centro de Biología molecular Severo Ochoa(CBm) Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid(CSIC-UAM)MadridSpain

The word “senescence” comes from the Latin senescens, meaning “to begin to age”, and is characterized by a long-lasting but reversible block in proliferation, resulting from stress-induced cell cycle arrest of pre... 详细信息

关键词： Latin potential lasting

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Bioinformatics Analysis on lncRNA and mRNA Expression Profiles for Novel Biological Features of Valvular Heart Disease with Atrial Fibrillation

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Journal of Electronic Science and Technology 2021年第1期19卷 53-69页

作者： Wei Zeng ni-ni Rao Ke Liu the School of Life Science and Technology University of Electronic Science and Technology of ChinaChengdu 610054 the Guangdong Institute of Electronic Information Engineering University of Electronic Science and Technology of ChinaDongguan 523107 the Department of Sichuan Academy of medical Science Sichuan Provincial People’s HospitalChengdu 610072

The biological features of the valvular heart disease with atrial fibrillation(AF-VHD)remain unknown when involving long non-coding RNAs(lncRNAs).This study performed system analysis on lncRNA and messenger RNA(mRNA)expression profiles constructed by using bioinformatics methods and tools for biological features of *** change and t-test were used to identify differentially expressed(DE)lncRNAs and *** enrichment analysis of DE mRNAs was *** subgroups formed by lncRNAs and nearby mRNAs were screened,and a transcriptional regulation network among lncRNAs,mRNAs,and transcription factors(TFs)was *** interactions between mRNAs related to lncRNAs and drugs were *** 620 AF-VHDrelated DE lncRNAs and 452 DE mRNAs were *** 3 lncRNA subgroups were *** 665 regulations mediated by lncRNAs and TFs were *** 9 mRNAs related to lncRNAs had 1 or more potential drug interactions,totaling 37 *** these,9 drugs targeting 3 genes are already known to be able to control or trigger atrial fibrillation(AF)or other cardiac *** found biological features of AF-VHD provide foundations for further biological experiments to better understand the roles of lncRNAs in development from the valvular heart disease(VHD)to AF-VHD.

关键词： Expression profiles long non-coding RNA(lncRNA) messenger RNA(mRNA) valvular heart disease(VHD) valvular heart disease with atrial fibrillation(AF-VHD).

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Survey on State of Baosteel Phase One m-type Coke Oven and Practices

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China's Refractories 2019年第3期28卷 8-14页

作者： ZHOU Haizhong LI Yong ni Shengqi Baoshan Iron & Steel Co. Ltd.

The phase one m-type coke oven in Baosteel was a large coke oven imported from nippon Steel&Sumitomo metal,which played an important role in the development of large-scaled coke ovens in *** investigating the shutting down process and the damage process of m-type coke oven body in Baosteel,the damage of used refractories in different parts,including carbonation chamber,combustion chamber,oven top,regenerative chamber,rising pipe,flue pipe and so on,was investigated and analyzed,which laid a good foundation for further damage analysis of coke oven body and improvement of maintenance in daily production.

关键词： coke oven refractories damage oven body

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Slip model for the 2011 m_w 9.0 Sendai (Japan) earthquake and its m_w 7.9 aftershock derived from GPS data

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Chinese Science Bulletin 2011年第27期56卷 2941-2947页

作者： DIAO FaQi XIONG Xiong ni SiDao ZHENG Yong GE Can Key Laboratory of Dynamic Geodesy Institute of Geodesy and Geophysics Chinese Academy of Sciences Wuhan 430077 China Graduate University of the Chinese Academy of Sciences Beijing 100049 China

用为 8 h 的测量 GPS 的 coseismic 和 seismic 以后排水量跟随 m w 2011 年 3 月 11 日， coseismic 和 seismic 以后差错的 9.0 仙台地震滑动模型基于一个分层的外壳的模型被开发。主要吃惊的测地学的时刻大小是被测量近似 m w 8.98。... 详细信息

用为 8 h 的测量 GPS 的 coseismic 和 seismic 以后排水量跟随 m w 2011 年 3 月 11 日， coseismic 和 seismic 以后差错的 9.0 仙台地震滑动模型基于一个分层的外壳的模型被开发。主要吃惊的测地学的时刻大小是被测量近似 m w 8.98。slip 展出清楚的反向的特征，与大约 23.3 m 的 hypocenter，和大小附近的最大值。某罢工滑倒行为可以发生在山峰破裂地区的二个方面上。主要吃惊释放的几乎 90% 地震时刻发生在深度不到 40 km。精力由差错释放了在跟随主要吃惊的 8 h 滑倒近似等于 m w 的地震 8.13。与 1.5 m 的最大值， seismic 以后滑倒在 coseismic 破裂差错的西南的部分被集中，它与 m w 的地点和行为同意很好 7.9 余震。这暗示在在主要吃惊以后的 8 h 的 seismic 以后变丑被 m w 主要导致 7.9 余震。另外， seismic 以后 0.20.4 m 滑倒在 coseismic 破裂的下面剧降延期被观察，它可能被在滑倒以后的效果在这个时期期间引起了。

关键词： GPS数据余震滑模式断层滑动 GPS测量破裂带地震矩地壳模型

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A FRAmEWORK FOR DOmAIN-SPECIFIC NATURAL LANGUAGE INFORmATION BROKERAGE

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Journal of Systems Science and Systems Engineering 2018年第5期27卷 559-585页

作者： Lin ni Jiamou Liu Department of Computer Science The University of Auckland New Zealand

Service providers - from public institutions to primary care facilities - need to constantly attend toclients＇ inquiries to provide useful information and directive guidelines. Ensuring high quality serviceis challenging as it not only demands detailed domain-specific knowledge, but also the ability toquickly understand the clients＇ issues through their diverse - and often casual - descriptions. Thispaper aims to provide a framework for the development of an automated information broker agent whoperforms the task of a helper. The main task of the agent is to interact with the client and direct them toobtain further services that cater their personalized need. To do so, the agent should accomplish asequence of tasks that include natural language inquiry, knowledge gathering, reasoning, and givingfeedback; in this way, it simulates a human helper to engage in interaction with the client. Theframework combines a question-answering reasoning mechanism while utilizing domain-specificknowledge base. When the users cannot describe clearly their needs, the system tries to narrow downthe possibilities by an iterative question-answering process, until it eventually identifies the target. Inrealizing our framework, we make a proof-of-concept project, m andy, a primary care chatbot systemcreated to assist healthcare staffs by automating the patient intake process. We describe in detail thesystem functionalities and design of the system, and evaluate our proof-of-concept on benchmark casestudies.

关键词： Question and answer system chatbot automated information broker iterative inquiry language processing AI and healthcare

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Transport mechanism in chemically reactive hybrid nanofluid flow containing gyrotactic micro-organisms over a curved oscillatory surface

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Applied mathematics and mechanics(English Edition) 2025年第1期46卷 177-192页

作者： m.NAVEED m.ImRAN T.ASGHAR Z.ABBAS Department of mathematics Division of Science and TechnologyUniversity of Education Department of mathematics The Islamia University of Bahawalpur

This paper examines the transport analysis, including both heat transfer and mass transfer, in hybrid nanofluid flow containing gyrotactic microorganisms towards a curved oscillatory surface. The influence of magnetic fields is also inspected in terms of their physical characteristics. To depict the phenomena of transport, modified versions of both Fick's and Fourier's laws are used. Additionally, the characteristics of both heterogeneous and homogeneous chemical reactions are also incorporated. Utilizing a curvilinear coordinate system, the flow problem is formulated as partial differential equations(PDEs)for momentum, concentration, microorganism field, and energy. An analytical solution to the obtained flow equations is achieved utilizing the homotopy analysis method(HAm).The effects of significant flow parameters on the pressure and microorganism fields, velocity, oscillation velocity, concentration, and temperature distributions are shown via graphs. Furthermore, the variations in skin friction, mass transfer rate, heat transfer rate, and local motile number due to different involved parameters are presented in tables and are analyzed in detail. Graphical results indicate that the curves of velocity and temperature fields are enhanced as the values of the solid volume fraction variables *** is also verified that the concentration rate field decreases as the values of the homogeneous reaction strength parameter and the radius of curvature parameter increase, and it increases with the Schmidt number and the heterogeneous reaction strength *** outcomes show a favorable response of the motile number to advanced values of the Peclet number, the Schmidt number, the microorganism difference parameter, and the bio-convective Lewis number.

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mViewer： mobile phone spatiotemporal data viewer

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Frontiers of Computer Science 2014年第2期8卷 298-315页

作者： Jiansu PU Siyuan LIU Panpan XU Huamin QU Lionel m. ni Department of Computer Science Hong Kong University of Science and Technology Hong Kong 999077 China iLab Heinz College Carnegie Mellon University Pittsburgh PA 15601 USA

Nowadays movement patterns and people＇s be- havioral models are needed for traffic engineers and city plan- ners. These observations could be used to reason about mobil- ity and its sustainability and to support decision makers with reliable information. The very same knowledge about human diaspora and behavior extracted from these data is also valu- able to the urban planner, so as to localize new services, orga- nize logistics systems and to detect changes as they occur in the movement behavior. moreover, it is interesting to inves- tigate movement in places like a shopping area or a working district either for commercial purposes or for improving the service quality. These kinds of tracking data are made avail- able by wireless and mobile communication technologies. It is now possible to record and collect a large amount of mobile phone calls in a city. Technologies for object tracking have recently become affordable and reliable and hence we were able to collect mobile phone data from a city in China from January 1, 2008 to December 31, 2008. The large amount of phone call records from mobile operators can be considered as life mates and sensors of persons to inform how many peo- ple are present in any given area and how many are entering or leaving. Each phone call record usually contains the caller and callee IDs, date and time, and the base station where the phone calls are made. As mobile phones are widely used in our daily life, many human behaviors can be revealed by an- alyzing mobile phone data. Through mobile phones, we can learn the information about locations, communications be- tween mobile phone users during their daily *** this work, we propose a comprehensive visual analysissystem named as mViewer, mobile phone spatiotemporal data Viewer, which is the first system to visualize and analyze the population＇s mobility patterns from millions of phone call records. Our system consists of three major components： 1） visual analysis of user groups in

关键词： visual analysis mobility pattern mobile phone

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Brain-penetrating neurotrophic factor mimetics: HER-096 as a disease-modifying therapy for Parkinson’s disease

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Neural Regeneration Research 2025年第4期20卷 1094-1095页

作者： Natalia Kulesskaya Kira m.Holmström Henri J.Huttunen Herantis Pharma Plc EspooFinland

Neurotrophic factors as a therapeutic approach in neurodegenerative diseases:A major unmet need in the field of central nervous system diseases is disease-modifying *** for decades there have been various symptomatic treatments available to alleviate the symptoms of the disease,disease-modification,*** that stop,significantly delay,or reverse the progression of the disease,has been turned out to a difficult goal to achieve.

关键词： diseases treatment therapeutic

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Arctic sea-ice extent: No record minimum in 2023 or recent years

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 52-55页

作者： Ola m.Johannessen Tor I.Olaussen Nansen Scientific Society BergenNorway Nansen Environmental and Remote Sensing Center BergenNorway

Arctic sea-ice extent reaches its minimum each year in September. On 11 September 2023 the minimum was 4.969 million square kilometers(***^(2)). This was not a record low, which occurred in 2012, when the minimum was 4.175 ***^(2), 0.794 ***^(2) less than the minimum in 2023. However, the ice extent had decreased by 0.432 ***^(2) compared with 2022. Nevertheless, the summer melting in 2023 was remarkably less than expected when considering the strong heat waves in the atmosphere and ocean, with record temperatures set around the world. In general, there is a high correlation between the long-term decrease in sea-ice extent and the increasing CO_(2) in the atmosphere, where the increase of CO_(2) in recent decades explains about 80% of the decrease in sea ice in September, while the remainder is caused by natural variability.

关键词： Sea ice Arctic minimum ice Climate

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