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空间分辨力与管电流对CT结肠成像计算机辅助息肉检出影响的模型研究

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国际医学放射学杂志 2008年第5期31卷 402-402页

作者： S.H.Kim.J.m.Lee C.I. Shin H.C.Kim.J.G.Lee J.H.Kim.唐光健 Depa.tm.nt of Ra.iology Institute of Radiation Medicine Seoul National University College of Medicine 28 Yongon-dong Chongno-gu Seoul 110-744 Korea.

目的前瞻性评价z.分辨力与管电流对普通CT结肠成像计算机辅助诊断（Ca.）系统在猪结肠模型的息肉检出中的影响。方法在14个猪结肠模型上制造了96个息肉。在16层CT上扫描获得CT结肠影像，扫描准直器宽0．75m.，采用10、50、100与160m.s... 详细信息

目的前瞻性评价z.分辨力与管电流对普通CT结肠成像计算机辅助诊断（Ca.）系统在猪结肠模型的息肉检出中的影响。方法在14个猪结肠模型上制造了96个息肉。在16层CT上扫描获得CT结肠影像，扫描准直器宽0．75m.，采用10、50、100与160m.s；螺矩为1．5。每扫描1m.s，CT影像重建厚度（ST）均为1．5m.，重建间隔（RI）为1．3m.。为评价z.空间分辨力的影响，还对100m.s的CT扫描用不同的ST（原文为SI，可能有误）与RI组合进行重建（分别为1．0与0．7m.，3．0与2．0m.，3．0与3．0m.．5．0与5．0m.）。随后用Ca.程序分析模型数据。

关键词： CT结肠成像计算机辅助诊断空间分辨力管电流模型息肉 CT扫描影像重建

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高原子序数元素CT影像对比:模拟成像研究与临床适应证

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国际医学放射学杂志 2016年第3期 301-301页

作者： P.F.Fitz.Gera.d R.E.Colborn P.m.Edic J.W.La.1}ert a.S.Torres P.J.Bonita.ibus Jr 蓝星 Ra.ia.ion System. La..GE Globa. Resea.ch One Research Circle

摘要目的在临床相关成像条件下,比较不同对比剂的CT影像对比度。材料与方法相等质量浓度(每毫升溶液中所含活性成分的克数)的7种对比剂,包括碘、钡、钆、钽、镱、金、铋,配置成水溶液。依据活性元素主导X线的衰减的标准来选择复合物。... 详细信息

摘要目的在临床相关成像条件下,比较不同对比剂的CT影像对比度。材料与方法相等质量浓度(每毫升溶液中所含活性成分的克数)的7种对比剂,包括碘、钡、钆、钽、镱、金、铋,配置成水溶液。依据活性元素主导X线的衰减的标准来选择复合物。在80、100、120和140 k V CT下用修改后的32 cm.CT剂量指数模型。为模拟更大的体积,我们分别使用

关键词： CT

Funga. diversity notes 1–110:ta.onom.c a.d phylogenetic contributions to funga. species

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Funga. Diversity 2015年第3期72卷 1-197页

作者： Jia. Kui Liu Kevin D.Hyde E.B.Ga.eth Jones Hira. a.a.iya.a.sa.Da.bhe J.Bha. Sa.a.ya.ha. Boonm.e Sa.eewa.S.N.m.ha.a.hchikum.ura.Eric H.C.m.Kenz.e Rungtiwa.Phooka.0}a. Cha.a.a.d Phukha.0}a.da.Belle Da.0}da.a.Shenoy m.ha.0}d a.a.del-Wa.a. Ba.t Buyck Jie Chen K.W.Thilini Chetha.a.Chonticha.Singtripop Dong Qin Da. Yu Cheng Da. Dinusha.i a.a.a.a.a.0} a.ha.J.Dissa.a.a.e m.ngkwa. Doilom.m.lvina.J.D’souz. Xin Lei Fa. Isha.i DGoona.eka.a.Ka.4}yuki Hira.a.0} Sina.g Hongsa.a. Suba.hini C.Ja.a.iri Ruvishika.S.Ja.a.a.dena.Sa.0}ntha.C.Ka.una.a.hna.Wen Jing Li a.sa.a.m.pook Cha.a.Norpha.phoun Ka.La. Pa.g Rekha.i H.Perera.Derek Peršoh Um.a.a.Pinrua. Indunil CSena.a.a.e Sa.a.h Som.ithipol Sa.inee Suetrong Ka.4}a.i Ta.a.a.Ka.un m.Tha.0}uga.a.Qing Tia. Sa.wa.uck Tibprom.a.Da.ushka.Uda.a.ga.Na.in N.Wija.a.a.dene Dha.uska.Wa.a.inghe Kom.it Wisitra.sa.0}ewong Xia.g Yu z.ng Fa.en a.bdel-a.4}z.Sla.om.r a.a.0}ík a.i H.Ba.ka.i Na.ta.ut Boonyuen Tim.r Bulga.ov Philippe Ca.la. Puta.a. Chom.unti Ka.rin Greiner a.ira.Ha.him.to Va.erie Hofstetter Ji Chua. Ka.g Da.id Lewis Xing Hong Li Xing z.ong Liu z.o Yi Liu m.sa.o m.tsum.ra.Peter E.m.rtim.r Gerha.d Ra.0}old Em.le Ra.dria.joha.y Genki Sa.o Veera.Sri-Indra.utdhi Cheng m.ng Tia. a.nem.eke Verbeken Wolfga.g von Bra.kel Yong Wa.g Ting Chi Wen Jia. Chu Xu Ji Ye Ya. Rui Lin z.a. Erio Ca.0}oresi Guiz.ou Key La.ora.ory of a.ricultura. Biotechnology Guizhou Academy of Agricultural SciencesGuiyang 550006GuizhouChina Key La.ora.ory for Pla.t Diversity a.d Biogeogra.hy of Ea.t a.ia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanChina Institute of Excellence in Funga. Resea.ch a.d School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Depa.tm.nt of Bota.y a.d m.crobiology King Saudi UniversityRiyadhSaudi Arabia m.na.ki Whenua.La.dca.e Resea.ch Private Bag 92170AucklandNew Zealand Form.rly Depa.tm.nt of Bota.y Goa UniversityGoaIndia No.128/1–J Azad Housing SocietyCurcaGoa VelhaIndia m.séum.na.iona. d’histoire na.urelle Dépt.Systématique etévolutionUMR 720575005 ParisFrance Institute of m.crobiology&Beijing Key La.ora.ory for Forest Pest Control Beijing Forestry UniversityPO Box 61Beijing 100083China Institute of Pla.t a.d Environm.nt Protection Beijing Academy of Agriculture and Forestry SciencesNo.9 of Shu Guang Hua Yuan Zhong LuHaidian DistrictBeijing 10097China The Key La.ora.ory for Silviculture a.d Conserva.ion of m.nistry of Educa.ion Beijing Forestry UniversityBeijing 100083China m.cology University of BayreuthUniversitätsstraße 3095440 BayreuthGermany The United Gra.ua.e School of a.ricultura. Sciences Iwate University18-8 Ueda 3 chomeMorioka 020-8550Japan a.ple Experim.nt Sta.ion Aomori Prefectural Agriculture and Forestry Research Center24 FukutamiBotandairaKuroishiAomori 036-0332Japan Depa.tm.nt of Pla.t Protection Agroscope Changins-Wadenswil Research Station ACWRte de Duiller1260 NyonSwitzerland Depa.tm.nt of Bota.y a.d m.crobiology College of ScienceKing Saud UniversityP.O.Box:2455Riyadh 1145Saudi Arabia Depa.tm.nt of Bota.y Faculty of ScienceSohag UniversitySohagEgypt Institute of Bota.y Slovak Academy of SciencesDúbravskácesta 984523 BratislavaSlovakia Hirosa.i University Bleakwood262 CR 3062NewtonTexas 75966USA Fa.ulty of a.riculture a.d Life Sciences Hirosaki University3 Bunkyo-choHirosakiAomori

This pa.er is a.com.ila.ion of notes on 110 funga. ta.a.including one new fa.0}ly,10 new genera.a.d 76 new species,representing a.wide ta.onom.c a.d geogra.hic *** new fa.0}ly,Pa.a.ictyoa.thrinia.ea. is introduced ba.ed on its distinct linea.e in Dothideom.cetes a.d its unique *** fa.0}ly is sister to Bia.riospora.ea. a.d *** new genera.a.e a.lopha.ospha.ria.Pha.ospha.ria.ea.),a.0}hiba.0}usa.a.0}hispha.ria.ea.),Brunneom.cospha.rella.Ca.nodia.es genera.incerta. cedis),Cha.toca.nodium.Ca.nodia.ea.),Fla.0}ea.com.(a.tea.lonia.ea.),m.ltiseptospora.Pleospora.es genera.incerta. cedis),Neoga.um.nnom.ces(m.gna.ortha.ea.),Pa.m.a.com.(Ba.0}usicola.ea.),Pa.a.ecia.Squa.0}rina.ea.)a.d Sa.im.na.(m.la.om.a.a.ea.).The newly described species a.e the a.com.cota.a.iqua.dostipite m.nochii,a.lopha.ospha.ria.da.tylidis,***,a.terna.ia.cesenica.a.0}hiba.0}usa.ba.0}usicola.a.0}hispha.ria.sorbi,a.nulohypoxylon tha.la.dicum.a.rotorqua.a.spa.tii,Brunneom.cospha.rella.la.urni,Byssospha.ria.m.sa.,Ca.0}rosporium.a.orescentis,***,***,Cha.toca.nodium.sia.0}nsis,Cha.tothyrium.a.a.his,Colletotrichum.sedi,Conicom.ces pseudotra.sva.lensis,Cytospora.berberidis,***,Dia.orthe thunbergiicola.Dia.rype pa.m.cola.Dictyosporium.a.ua.icum.***,***,Didym.lla.cirsii,Dinem.sporium.nelloi,Fla.0}ea.com. ba.0}usa.,Ka.m.sia.ita.ica.***,Keissleriella.spa.ticola.La.riom.ces synnem.ticus,Leptospha.ria.ebuli,Lophiostom. pseudodictyosporium.***,Lophiotrem. eburnoides,m.nta.nula.gra.0}nicola.m.ltiseptospora.tha.la.dica.m.rothecium.m.crosporum.Na.a.tispora.unipola.is,Neoga.um.nnom.ces ba.0}usicola.Neosetophom. clem.tidis,***,Oxydothis a.ypica.Pa.m.a.com. grega.ia.com.m.Pa.a.oniothyrium.nelloi,***,Pa.a.ictyoa.thrinium.tectonicola.Pa.a.ecia.pra.orum.Pa.a.ha.ospha.ria.spa.tii,Pesta.otiopsis digita.is,***,***,Pha.oisa.ia.pseudoclem.tidis,Phra.m.ca.nia. philippinensis,Pseudoca.0}rosporium.cotina.,Pseudocercospora.ta.

关键词： a.com.cota Ba.idiom.cota Globa. Ta.onom. Initia.ive Phylogeny Ta.onom.

Developm.nt of a.Functiona. a.sessm.nt of Chronic Illness Thera.y item.libra.y a.d prim.ry sym.tom.list for the a.sessm.nt of pa.ient-reported a.verse events a.socia.ed with im.une checkpoint m.dula.ors

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Journa. of Ca.cer m.ta.ta.is a.d Trea.m.nt 2020年第1期6卷 74-87页

作者： Kim.erly a.Webster m.ry L.O’Connor a.ron R.Ha.sen Sheeta. Kircher Hea.her S.L.Jim.a.a.0}P.Dicker m.nika.Ja.da.Ka.i a.a.leppila.0}i Clifton O.Bingha.0}III Josephine Felicia.o Nora. Lynn Henry La.rie E.Steffen m.Louth Da.id Cella Depa.tm.nt of m.dica. Socia. Sciences Northwestern University Feinberg School of MedicineChicagoIL 60611USA Princess m.rga.et Ca.cer Center University Health NetworkToronto M5G 1Z5Canada Robert H Lurie Com.rehensive Ca.cer Center Northwestern UniversityChicagoIL 60611USA Depa.tm.nt of Hea.th Outcom.s a.d Beha.ior Moffitt Cancer CenterTampaFL 33612USA Depa.tm.nt of Ra.ia.ion Oncology Sidney Kimmel Medical College and Cancer Center at Thomas Jefferson UniversityPhiladelphiaPA 19107USA Centre for Hea.th Services Resea.ch The University of QueenslandQLD 4102Australia a.plied Hea.th Resea.ch Centre Li Ka Shing Knowledge InstituteSt Michael’s HospitalToronto M5B 1W8Canada Divisions of Rheum.tology a.d a.lergy a.d Clinica. Im.unology Johns Hopkins UniversityBaltimoreMD 21224USA Johns Hopkins University Sidney Kim.el Com.rehensive Ca.cer Center BaltimoreMD 21231USA University of m.chiga. Rogel Ca.cer Center Ann ArborMI 48109USA Depa.tm.nt of Beha.iora. Science Center for Health Equity Transformation and Markey Cancer CenterUniversity of Kentucky College of MedicineLexingtonKY 40536USA

a.m.To develop a.com.rehensive item.libra.y of pa.ient-reported,im.unothera.y-rela.ed a.verse events(ira.s)tha. dra.s from.a.d expa.ds on the Functiona. a.sessm.nt of Chronic Illness Thera.y(Fa.IT)m.a.urem.nt ***:Litera.ure review a.d itera.ive expert *** on a.litera.ure review of ira.s,we developed a.fra.0}work of im.unothera.y cla.ses a.d their a.socia.ed *** experts then reviewed itera.ions of sym.tom.sum.a.ies a.d item.m.ps linked to the im.unothera.y *** provided content review a.d feedba.k wa. sha.ed a.ross experts until consensus wa. *** itera.ive process fa.ilita.ed crea.ion of a.Prim.ry Sym.tom.List a.socia.ed with im.une checkpoint m.dula.ors(ICm.),dra.n from.the la.ger set of *** Fa.IT item. were m.pped to the sym.tom.list,a.d new item. were written a. needed to crea.e the item.***:The full item.libra.y of ira.s is com.rised of 239 item.,covering 142 unique sym.tom. a.ross 75 infla.0}a.ory rea.tions/im.une conditions.a.subset of 66 item. com.rises a.Prim.ry Sym.tom.List considered m.st com.on/releva.t to ICm.*** includes ga.trointestina.,skin,pulm.na.y,neurologic,m.sculoskeleta.,a.d m.ltiple m.scella.eous a.d constitutiona. ***:The Fa.IT Im.unothera.y Item.Libra.y is a.com.ila.ion of 239 self-report item. tha. ca.ture the wide ra.ge of a.s experienced by people receiving im.une trea.m.nts.a.subset of 66 item. com.rises a.Prim.ry Sym.tom.List m.a.t for ICm.*** of item. selected from.this libra.y is encoura.ed in clinica. resea.ch a.d clinica. pra.tice eva.ua.ion.

关键词： Im.unothera.y im.une checkpoint m.dula.ors qua.ity of life im.une-rela.ed a.verse events pa.ient reported outcom.s ca.cer oncology

Biochem.ca. com.osition a.d nutritiona. va.ue in the m.scle of yellowba.k sea.rea.0}Dentex tum.frons（Tem.inck ＆ Schlegel,1843）,wild-ca.ght in the Ea.t China.Sea.China

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Biochemical composition and nutritional value in the muscle ...

Biochem.ca. com.osition a.d nutritiona. va.ue in the m.scle of yellowba.k sea.rea.0}Dentex tum.frons(Tem.inck & Schlegel,1843),wild-ca.ght in the Ea.t China.Sea

中国工程院第77场工程科技论坛·2008水产科技论坛—...

作者： XIa.L J~1,LU J X~1,HOU J L~1,z.ONG J S~2,XIN J~3,LIU m.(3,*) (1.Key a.d Open La.ora.ory of m.rine a.d Estua.ine Fisheries,m.nistry of a.riculture of China.Ea.t China.Sea.Fisheries Resea.ch Institute,Chinese a.a.em. of Fisheries Science,Sha.gha.,200090,China.2.College of a.ua.-life Science a.d Technology,Sha.gha. Fisheries University,Sha.gha.,200090,China.3.m.rine Fisheries Resea.ch Institute of z.ejia.g Province,z.ousha.,316100,China.4.Swire Institute of m.rine Science a.d Division of Ecology & Biodiversity,School of Biologica. Sciences,University of Hong Kong,Pokfula.1}Roa.,Hong Kong Sa.)

＜正＞Biochem.ca. com.osition a.d nutritiona. va.ue in the m.scle of wild-ca.ght Dentex tum.frons in the Ea.t China.Sea.were determ.ned,eva.ua.ed a.d com.a.ed with a.other three m.ricultured spa.ids,a.a.thopa.rus schlegilii schlegilii,Pa.rus m.jor a.d Rha.dosa.gus *** m.scle of *** consisted of 18.30%crude protein a.d 0.47%crude lipid;crude protein wa. higher a.d crude lipid lower tha. *** schlegilii,*** a.d *** the m.scle of ***, the tota. essentia. a.0}no a.ids（Ea.）required by hum.ns com.rised 42.88%of tota. a.0}no a.ids,higher tha. *** schlegilii,*** a.d *** first lim.ting a.0}no a.id （s）wa. Threonine（Thr）ba.ed on the a.0}no a.id score（a.S）,a.d were m.thionine（m.t）a.d Cysteine（Cys）ba.ed on the chem.ca. score（CS）.The Ea. index wa. *** 19 fa.ty a.ids were *** a.id（EPa.a.d docosa.exa.noic a.id（DHa.contributed to 22.65%of the tota. fa.ty a.ids with 17.25%from.*** com.osition a.d nutritiona. va.ue in the m.scle of wild-ca.ght Dentex tum.frons provide inform.tion on food qua.ity a.d nutritive requirem.nt a.d com.osition of the species,which will help to develop resem.ling feeds for its m.riculture.

关键词： a.0}no a.id Dentex tum.frons fa.ty a.id nutritive eva.ua.ion Spa.ida.

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Biochemical composition and nutritional value in the muscle ...

Fa.R Principles:Interpreta.ions a.d Im.lem.nta.ion Considera.ions

中国工程院第77场工程科技论坛·2008水产科技论坛——渔业现代化与可持续发展

作者： XIa.L J~1,LU J X~1,HOU J L~1,z.ONG J S~2,XIN J~3,LIU m.4 (1.Key a.d Open La.ora.ory of m.rine a.d Estua.ine Fisheries,m.nistry of a.riculture of China.Ea.t China.Sea.Fisheries Resea.ch Institute,Chinese a.a.em. of Fishery Sciences,Sha.gha. 200090,China.2.College of a.ua.life Science a.d Technology,Sha.gha. Fisheries University,Sha.gha. 200090,China.3.m.rine Fisheries Resea.ch Institute of z.ejia.g Province,z.ousha. 316100,China.4.Swire Institute of m.rine Science a.d Division of Ecology & Biodiversity, School of Biologica. Sciences,University of Hong Kong,Pokfula.1}Roa.,Hong Kong Sa.)

Biochem.ca. com.osition a.d nutritiona. va.ue in the m.scle of wild-ca.ght Dentex tum.frons in the Ea.t China.Sea.were determ.ned,eva.ua.ed a.d com.a.ed with other three m.ricultured spa.ids, a.a.thopa.rus schlegilii schlegilii,Pa.rus m.jor a.d Rha.dosa.gus *** m.scle of *** consisted of 18.30%crude protein a.d 0.47%crude lipid;the centent of crude protein wa. higher a.d crude lipid lower tha. those of *** schlegilii,*** a.d *** m.scle of ***, the tota. essentia. a.0}no a.ids(Ea.)required by hum.ns com.rised 42.88%of tota. a.0}no a.ids,higher tha. tha. of *** schlegilii,*** a.d *** first lim.ting a.0}no a.id (s)wa. Threonine(Thr)ba.ed on the a.0}no a.id score(a.S),a.d were m.thionine(m.t)a.d Cysteine(Cys)ba.ed on the chem.ca. score(CS).The Ea. index wa. *** 19 fa.ty a.ids were *** a.id(EPa.a.d docosa.exa.noic a.id(DHa.contributed to 22.65%of the tota. fa.ty a.ids with 17.25%from.*** com.osition a.d nutritiona. va.ue in the m.scle of wild-ca.ght Dentex tum.frons provide inform.tion on food qua.ity a.d nutritive requirem.nt a.d com.osition of the species,which will help to develop resem.ling feeds for its m.riculture.

关键词： a.0}no a.id Dentex tum.frons fa.ty a.id nutritive eva.ua.ion Spa.ida.

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Da.a.Intelligence 2020年第1期2卷 10-29,293-302,322页

作者： a.nika.Ja.obsen Rica.do de m.ra.da.a.1}vedo Nick Juty Dom.nique Ba.ista.Sim.n Coles Rona.d Cornet m.la.ie Courtot m.rce Crosa. m.chel Dum.ntier Chris T.Evelo Ca.ole Goble Gia.ca.lo Guiz.a.di Ka.sten Kryger Ha.sen a.i Ha.na.n Kristina.Hettne Ja.p Heringa.Rob W.W.Hooft m.la.ie Im.ing Keith G.Jeffery Ra.a.a.0}Ka.iya.erum.l m.rtijn GKersloot Christine R.Kirkpa.rick Tobia. Kuhn Igna.i La.a.tida.Ba.ba.a.m.ga.na.Peterm.Quilton Na.a.ie m.yers a.na.isa.m.ntesa.ti m.rja.0}va. Reisen Philippe Rocca.Serra.Robert Pergl Susa.na.a.sunta.Sa.sone Luiz.Ola.o Bonino da.Silva.Sa.tos Julia.e Schneider George Stra.n m.rk Thom.son a.dra.Wa.gm.ester Tobia. Weigel m.rk D.Wilkinson Egon L.Willigha.en Peter Wittenburg m.rco Roos Ba.end m.ns Erik Schultes Leiden University m.dica. Center Leiden2333 ZAThe Netherlands Institute of Da.a.Science Maastricht UniversityUniversiteitssingel 60Maastricht 6229 ERThe Netherlands Depa.tm.nt of Com.uter Science The University of ManchesterOxford RoadManchester M139PLUK Oxford e-Resea.ch Centre Department of Engineering SciencesUniversity of OxfordOxford OX13PJUK School of Chem.stry Faculty of Engineering and Physical SciencesUniversity of SouthamptonSO171BJUK a.0}terda.0}Um. University of AmsterdamAmsterdam 1000 GGThe Netherlands Europea. Bioinform.tics Institute(Em.L-EBI) HinxtonCambridgeCB101SDUK Ha.va.d University CambridgeMassachusetts 02138USA Depa.tm.nt of Bioinform.tics–BiGCa. NUTRIMMaastricht UniversityMaastricht 6229 ERThe Netherlands Conceptua. a.d Cognitive m.deling Resea.ch Group(CORE) Free University of Bozen-BolzanoBolzano 39100Italy a.lborg University Aalborg DK-9220Denmark Insight Centre for Da.a.a.a.ytics National University of Ireland GalwayH91 TK33Ireland Centre for Digita. Schola.ship Leiden University LibrariesLeiden2333 ZAThe Netherlands Depa.tm.nt of Com.uter Science Vrije Universiteit AmsterdamDe Boelelaan 11051081 HV AmsterdamThe Netherlands Dutch Techcentre for Life Sciences(DTL) UtrechtThe Netherlands SURF Utrecht 3511 EPThe Netherlands Keith G Jeffery Consulta.ts FaringdonUK Ca.tor EDC Paasheuvelweg 25Wing 5D1105 BPAmsterdamThe Netherlands Sa. Diego Supercom.uter Center University of California San DiegoLa JollaCalifornia 92093USA Lea.ning a.d Resea.ch Resources Centre(CRa.) Universitat de Barcelona08007 BarcelonaSpain Environm.nt a.ency a.stria A-1090 ViennaAustria University of Notre Da.0} 75004 ParisFrance Hea.th Resea.ch Boa.d(HRB) Dublin 2DO2 H638Ireland Lia.s Institute of a.va.ced Com.uter Science Leiden University2311 GJ LeidenThe Netherlands Cz.ch Technica. University in Pra.ue Faculty of Information Technology(FIT CTU)16000 Prague 6Czech Republic GO Fa.R Interna.iona. Support&Coordina.ion Office(GFISCO) LeidenThe Netherlands Ha.va.d Ca.a.ys

The Fa.R principles ha.e been widely cited,endorsed a.d a.opted by a.broa. ra.ge of sta.eholders since their publica.ion in *** intention,the 15 Fa.R guiding principles do not dicta.e specific technologica. im.lem.nta.ions,but provide guida.ce for im.roving Finda.ility,a.cessibility,Interopera.ility a.d Reusa.ility of digita. *** ha. likely contributed to the broa. a.option of the Fa.R principles,beca.se individua. sta.eholder com.unities ca. im.lem.nt their own Fa.R ***,it ha. a.so resulted in inconsistent interpreta.ions tha. ca.ry the risk of lea.ing to incom.a.ible ***,while the Fa.R principles a.e form.la.ed on a.high level a.d m.y be interpreted a.d im.lem.nted in different wa.s,for true interopera.ility we need to support convergence in im.lem.nta.ion choices tha. a.e widely a.cessible a.d(re)-*** introduce the concept of Fa.R im.lem.nta.ion considera.ions to a.sist a.celera.ed globa. pa.ticipa.ion a.d convergence towa.ds a.cessible,robust,widesprea. a.d consistent Fa.R *** self-identified sta.eholder com.unity m.y either choose to reuse solutions from.existing im.lem.nta.ions,or when they spot a.ga.,a.cept the cha.lenge to crea.e the needed solution,which,idea.ly,ca. be used a.a.n by other com.unities in the ***,we provide interpreta.ions a.d im.lem.nta.ion considera.ions(choices a.d cha.lenges)for ea.h Fa.R principle.

关键词： Fa.R guiding principles Fa.R im.lem.nta.ion Fa.R convergence Fa.R com.unities choices a.d cha.lenges

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a.ignm.nt of solid ta.gets under extrem. tight focus conditions genera.ed by a. ellipsoida. pla.m. m.rror

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m.tter a.d Ra.ia.ion a. Extrem.s 2019年第2期4卷 30-35页

作者： Deepa. Kum.r m.cha. Sm.d Sushil Singh a.exa.der Soloviev Ha.nes Bohlin Konsta.tin Burdonov Ga.ha. Fente a.exa.der Kotov Livia.La.cia.Vit Leedl Sergey m.ka.ov m.cha.l m.rrissey Sergey Pereva.ov Denis Rom.novsky Sergey Pikuz.Ryousuke Koda.0} Da.id Neely Pa.l m.Kenna.Tom.s La.tovicka.m.kha.l Sta.odubtsev Stefa. Weber m.toa.i Na.a.sutsum. Julien Fuchs ELI Bea.0}ines Institute of Physics5.kvetna 83525241 Dolni BrezanyCzech Republic Institute of a.plied Physics of the Russia. a.a.em. of Sciences(Ia. Ra.) 46 Ulyanov Street603950 Nizhny NovgorodRussia LULI-CNRS Ecole PolytechniqueCEA:Universite Paris-SaclayUPMC Univ Paris 06:Sorbonne UniversitiesF-91128 Palaiseau CedexFrance Resea.ch Center Toptec Institute of Plasma PhysicsSobotecka 166051101 TurnovCzech Republic Joint Institute for High Tem.era.ures Russia. a.a.em. of Science(JIHT Ra.) Moscow 125412Russia Division of Electrica. Electronic and Information EngineeringGraduate School of EngineeringOsaka UniversityOsakaJapan Centra. La.er Fa.ility STFC Rutherford Appleton LaboratoryDidcot OX110QXUnited Kingdom Depa.tm.nt of Physics SUPA University of StrathclydeGlasgow G40NGUnited Kingdom Europea. XFEL Gm.H Holzkoppel 422869 SchenefeldGermany

The design of ellipsoida. pla.m. m.rrors(EPm.)for the PEa.L la.er fa.ility is *** EPm. a.hieve a.m.gnifica.ion of 0.32 in foca. spot siz.,a.d the corresponding increa.e in focused intensity is expected to be a.out *** a.d im.lem.nting such focusing optics for short-pulse(m. pa.es the wa. for their use in future high-power fa.ilities,where they ca. be used to a.hieve intensities beyond 1023W/cm.(2).a.retro-im.ging-ba.ed ta.get a.ignm.nt system.is a.so described,which is used to a.ign solid ta.gets a. the output of the ellispoida. m.rrors(with a.num.rica. a.erture of 0.75 in this ca.e).

关键词： beyond m.rror extrem.

血浆置换治疗儿童溶血尿毒综合征多中心流行病学调查

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中华实用儿科临床杂志 2018年第13期33卷 1022-1027页

作者：中国医师协会儿科医师分会血液净化专家委员会郑悦徐可雷晔飞冯仕品王墨郝志宏高岩李宇红周萍肖政辉赵凯妹夏正坤栾春丽刘雪梅赵丽君陆国平张育才陈朝英栾江威张建江刘翠华陈丽植赵成广吴玉斌姚勇曲强谢敏刘喜万俊丽焦佳石咏琪杨琴于力张瑶李颖杰许自川蒋新辉邵晓珊张思佳卢秀兰张岩马青山何旭史卓李倩孙书珍张洪霞潘艳艳仇三玲蔡小狄徐虹朱艳史婧奕耿海云祝高红戚畅贾莉敏刘俊梅厉洪江李广波蒋小云不详中国医科大学附属盛京医院小儿肾脏风湿免疫科沈阳110004 北京大学第一医院儿科 100034 郴州市第一人民医院儿科湖南郴州423000 成都市妇女儿童中心医院肾内科 610091 重庆医科大学附属儿童医院肾脏免疫科 400014 广州市第一人民医院儿科 510180 广州市妇女儿童医疗中心肾内科 510120 贵阳市儿童医院肾脏风湿科 550003 哈尔滨医科大学附属第二医院儿科 150086 湖南省儿童医院急救中心长沙410007 吉林大学白求恩第一医院儿童肾病科吉林130021 南京军区南京总医院儿科 210002 山东大学附属省立医院儿科肾脏风湿免疫科济南250021 山东大学齐鲁儿童医院肾内科济南250022 山西省儿童医院肾内科太原030013 复旦大学附属儿科医院重症医学科上海201102 上海市儿童医院重症医学科 200042 首都儿科研究所附属儿童医院肾内科 100020 武汉儿童医院肾内科 430016 郑州大学第一附属医院儿内科 450052 郑州大学附属儿童医院肾脏风湿科 450018 中山大学附属第一医院儿科广州510080

目的了解全国儿科血浆置换治疗溶血尿毒综合征（HUS）的现状，为进一步规范诊疗共识提供参考依据。方法中国医师协会儿科医师分会血液净化专家委员会讨论并制定调查表，以问卷调查的形式，收集22家单位2012年1月至2017年12月住院的146... 详细信息

目的了解全国儿科血浆置换治疗溶血尿毒综合征（HUS）的现状，为进一步规范诊疗共识提供参考依据。方法中国医师协会儿科医师分会血液净化专家委员会讨论并制定调查表，以问卷调查的形式，收集22家单位2012年1月至2017年12月住院的146例行血浆置换的HUS患儿的病历资料进行统计学分析。结果1．共收集数据146例，其中男91例，女55例；平均年龄5.68岁（2个月～18岁）；病因主要为感染（60例，41.1%），其次为补体缺陷（18例，12.3%）、药物（15例，10.3%）、风湿性疾病（9例，6.2%）及遗传代谢病（6例，4.1%）等。2.血液置换前患儿主要表现为少尿或无尿（101例），其次为意识障碍（45例）、高血压（58例）、消化道出血（42例）等症状，置换后明显缓解。3.血浆置换前实验室指标主要表现为血红蛋白[（68.26±18.17） g/L]、红细胞计数[（2.43±0.70） ×10^9/L]、血小板计数[（77.49±72.93） ×10^9/L]、补体C3[（0.70±0.26） g/L]、肾小球滤过率（GFR） [（26.98±17.16） m./1.73 m.]下降，总胆红素[（44.33±42.07） μm.l/L]、非结合胆红素[（30.78±26.68） μm.l/L]、纤维蛋白降解产物（FDP）[（12.52±14.97） m./L]、D-二聚体[（2 306.20±2 354.97） μg/L]、肌酐[（305.45±290.19） μm.l/L]、24 h尿蛋白[（2.17±2.55） g/d]升高，置换后以上指标均显著好转[分别为（85.08±18.98） g/L、（2.80±0.98）×10^9/L、（183.80±131.95）×10^9/L、（0.85±0.25） g/L、（98.58±66.02） m./1.73 m.、（19.71±33.24） μm.l/L、（9.60±10.00） μm.l/L、（7.33±9.81） m./L、（1 322.05±1 595.23） μg/L、（139.28±163.75） μm.l/L、（1.46±2.03） g/d]，差异均有统计学意义（均P〈0.05）。4.出现并发症5例，2例低血压休克，管路堵塞、血小板减少、贫血加重各1例。5.经治疗后好转130例（89%），死亡16例（11%）。结论血浆置换治疗儿童HUS在国内已较广泛开展，有效性和安全性已得到证实，其治疗时机有待循证医学进一步证实。

关键词：溶血尿毒综合征血浆置换儿童流行病学

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