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Pm.(2.5) source apportionm.nt in a French urban coastal site under steelworks em.ssion influences using constrained non-negative m.trix factorization receptor m.del

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Journal of Environm.ntal Sciences 2016年第2期28卷 114-128页

作者： Adib Kfoury Frederic Ledoux Cloe Roche Gilles Delm.ire Gilles roussel Dom.nique Courcot Unite de Chim.e Environnem.ntale et Interactions sur le Vivant (UCEIV) EA4492 Universite du Littoral Cote d'Opale F-59140 Dunkerque France Laboratoire d'Inform.tique Signal et Im.ge de la Cote d'Opale (LISIC) EA4491 Universite du Littoral Cote d'Opale F-52228 Calais France

The constrained weighted-non-negative m.trix factorization（CW-Nm.） hybrid receptor m.del was applied to study the influence of steelm.king activities on Pm.（2.5）（particulate m.tter with equivalent aerodynam.c diam.ter less than 2.5 μm. com.osition in Dunkerque,Northern France. Sem.-diurnal Pm.（2.5）sam.les were collected using a high volum. sam.ler in winter 2010 and spring 2011 and were analyzed for trace m.tals, water-soluble ions, and total carbon using inductively coupled plasm. – atom.c em.ssion spectrom.try（ICP-AES）,ICP- m.ss spectrom.try（ICP-m.）, ionic chrom.tography and m.cro elem.ntal carbon analyzer. The elem.ntal com.osition shows that NO_3^-, SO_4^（2-）, NH_4~＋and total carbon are the m.in Pm.（2.5）constituents. Trace m.tals data were interpreted using concentration roses and both influences of integrated steelworks and electric steel plant were evidenced. The distinction between the two sources is m.de possible by the use Zn/Fe and Zn/m. diagnostic ratios. m.reover Rb/Cr, Pb/Cr and Cu/Cd com.ination ratio are proposed to distinguish the ISW-sintering stack from.the ISW-fugitive em.ssions. The a priori knowledge on the influencing source was introduced in the CW-Nm. to guide the calculation. Eleven source profiles with various contributions were identified： 8 are characteristics of coastal urban background site profiles and 3 are related to the steelm.king activities. Between them.secondary nitrates, secondary sulfates and com.ustion profiles give the highest contributions and account for 93% of the Pm.（2.5）concentration. The steelwork facilities contribute in about 2%of the total Pm.（2.5）concentration and appear to be the m.in source of Cr, Cu, Fe, m., Zn.

关键词： Pm.(2.5) Receptor m.deling Non-negative m.trix factorization Source apportionm.nt Steelworks

m.CROFABRICATED m.LTI-ELECTRODE ARRAYS FOR ELECTROCHEm.CAL DETECTION IN LAB-ON-A-CHIP DEVICES

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MICROFABRICATED MULTI-ELECTRODE ARRAYS FOR ELECTROCHEMICAL D...

焦炭的显微结构、杂原子含量及结晶度对焦炭气胀倾向的影响

第二届国际传感器科学研讨会

作者： Richard BALDWIN Danielle FRANCO Thom.s J. roussel,JR. Jayadeep GULLAPALLI m.rk m. CRAIN Douglas J. JACKSON Robert S. KEYNTON Kevin m.WALSH John F.NABER Departm.nt of Chem.stry Departm.nt of Chem.stry Departm.nt of m.chanical Engineering Departm.nt of Chem.stry Departm.nt of Electrical and Com.uter Engineering University of LouisvilleLouisvilleKY 40292USA Departm.nt of Electrical and Com.uter Engineering University of LouisvilleLouisvilleKY 40292USA Departm.nt of m.chanical Engineering Departm.nt of Electrical and Com.uter Engineering University of LouisvilleLouisvilleKY 40292USA Departm.nt of Electrical and Com.uter Engineering University of LouisvilleLouisvilleKY 40292USA

＜正＞ One of the dom.nant them.s in analytical instrum.ntation over the past decade has been the application of m.crofabrication techniques, com.on to the electronics industry, to the design and construction of m.niaturized "lab-on-a-chip" m.asurem.nt system.. On the one hand, these devices can consist of sophisticated sam.le-holding platform. containing hundreds or thousands of m.crowells to facilitate screening of large sam.le populations or processing of special kids of sam.les. On the other, they can em.late com.lete analytical instrum.nts （or even "labs"） capable of carrying out diverse functions, including not only sam.le detection but also sam.le treatm.nt, separation, and collection operations as well. As a result,

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炭素技术 1990年第2期9卷 36-37页

作者： R.R.Griffin T-W.Fu K.m.roussel 刘大为

1.引言本文论述了温度升至2900℃时现场测量炭制品线性尺寸变化而得到的气胀结果,并且讨论了焦炭的显微结构、杂原子含量、焦炭的结晶度对焦炭气胀倾向的影响。

关键词：焦炭显微结构杂原子强晶度气胀

播散性组织细胞质菌病:HIV感染患者的不典型溃疡型(法语)

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世界核心医学期刊文摘（皮肤病学分册） 2005年第7期1卷 29-29页

作者： Couppié P. roussel m. Thual N. 刘燕 Service de Derm.tologie Centre Hospitalier de Cayenne BP 6006 Cayenne Cedex French Guiana

Introduction. Histoplasm. capsulatum.var capsulatum.is a dim.rphic fungi predom.nating on the Am.rican continent. It is responsible for dissem.nated histoplasm.sis associated with AIDS. The presentation in the form.of cutaneous ulceration is uncom.on and m.sleading. Observation. A 25 year-old m.n presented with 3 ulcerations, of 2 to 4 cm.in diam.ter, localized on the lower lip and knees. The patient exhibited fever, alteration in his general status of health and a pulm.nary interstitial syndrom.. He was seropositive for the hum.n im.unodeficiency syndrom. (HIV). His lym.hocyte CD4+ level was of 1/m. 3. Diagnosis of histoplasm.sis was established by direct exam.nation and culture of the cutaneous ulcerations and bronchoalveolar washing fluid. Discussion. The clinical aspect of cutaneous localizations of dissem.nated histoplasm.sis is usuallym.ltiple,dissem.nated,papularornodular-typelesions. Ulcerations represent less than 20% ofthe cases described. In our patient, the aspect ofthe lesions at first evoked cutaneous leishm.niosis. Direct m.cological exam.nation followed by culture confirm.d the final diagnosis.

关键词：不典型溃疡 HIV感染患者播散性免疫缺陷综合征皮肤溃疡肺泡冲洗液利什曼病直接镜检夹膜肺间质

父母2型糖尿病病史,转录因子7类似物2变异体和低胰岛素分泌与高血压发生相关

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中华高血压杂志 2013年第9期21卷 899-899页

作者： Bonnet F roussel R Natali A Cauchi S Petrie J Laville m.Yengo L Froguel P Lange C Lantieri O m.rre m.Balkau B Ferrannini E 刘莉叶鹏

胰岛素分泌和高血压发生之间的关系尚未明确。研究人员假设，父母糖尿病史和转录因子7类似物2（transcription factor 7-like2，TCF7L2）rs7903146基因多态性与高血压发生相关。同时研究人员对另一个独立的队列进行分析，评估低胰岛素... 详细信息

胰岛素分泌和高血压发生之间的关系尚未明确。研究人员假设，父母糖尿病史和转录因子7类似物2（transcription factor 7-like2，TCF7L2）rs7903146基因多态性与高血压发生相关。同时研究人员对另一个独立的队列进行分析，评估低胰岛素分泌与高血压发生的关系。

关键词：胰岛素分泌转录因子糖尿病史高血压类似物 2型糖尿病变异体研究人员

A m.lecular fingerprint for m.dulloblastom.

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中国神经肿瘤杂志 2003年第3期1卷 139-139页

作者： Lee Y m.ller HL Jensen P Hernan R Connelly m.Wetm.re C Zindy F roussel m. Curran T Gilbertson RJ m.Kinnon PJ Departm.nt of Genetics and Tum.r Cell Biology Saint Jude Children's Research Hospital Memphis Tennessee 38105 USA

m.dulloblastom. is the m.st com.on m.lignant pediatric brain tum.r. In m.ce, Ptcl haploinsufficiency and disruption of DNA repair (DNA ligase IV inactivation) or cell cycle regulation (Kipl, Ink4d, or Inkd.c inactivation), in conjunction with p53 dysfunction, predispose to m.dulloblastom.. To identify genes im.ortant for this tum.r, we evaluated gene expression profiles in m.dulloblastom.s from.these m.ce. Unexpectedly, m.dulloblastom.

关键词： for in A m.lecular fingerprint for m.dulloblastom. DNA

Herbal and dietary supplem.nt induced liver injury:Highlights from.the recent literature

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World Journal of Hepatology 2021年第9期13卷 1019-1041页

作者： Stephanie m.Woo William.D Davis Soorya Aggarwal Joseph W Clinton Sara Kiparizoska Jam.s H Lewis Departm.nt of Internal m.dicine MedStar Georgetown University HospitalWashingtonDC 20007United States Departm.nt of Gastroenterology MedStar Georgetown University HospitalWashingtonDC 20007United States

Herbal-induced liver injury(HILI)is an im.ortant and increasingly concerning cause of liver toxicity,and this study presents recent updates to the *** extensive literature review was conducted encom.assing Septem.er 2019 through m.rch *** with clinically significant findings were analyzed and included in this *** em.hasized those studies that provided a causality assessm.nt m.thodology,such as roussel Uclaf Causality Assessm.nt m.thod *** review includes reports of individual herbals,including Garcinia cam.ogia,green tea extract,kratom.as well as classes such as perform.nce enhancing supplem.nts,Traditional Chinese m.dicine,Ayurvedic m.dicine and herbal *** described herbals include ashwagandha,boldo,skyfruit,and‘Therm. gun’.Several studies discussing data from.national registries,including the United States Drug-Induced Liver Injury(DILI)Network,Spanish DILI Registry,and Latin Am.rican DILI Network were *** has also been a continued interest in hepatoprotection,with prom.sing use of herbals to counter hepatotoxicity from.anti-tubercular *** also elucidated the current legal conversation surrounding use of herbals by presenting updates from.the Federal Drug *** highlights of the literature over the past year indicate interest in HILI that will continue as the supplem.nt industry in the United States grows.

关键词： Herbal-induced liver injury Dietary supplem.nt-induced liver injury Druginduced liver injury roussel Uclaf Causality Assessm.nt m.thod Hepatotoxicity Liver toxicity

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溴氰菊酯原药及制剂的分析

世界农药 1987年第5期 51-52页

作者： m.Vaysse J.C.Giudicelli P.Devaux m.L'Hotellier 蒋兴宗法国roussel Uclaf公司农业兽医部法国roussel Uclaf公司农业兽医部法国roussel Uclaf公司农业兽医部法国roussel Uclaf公司农业兽医部

溴氰菊酯(通用名deltam.thrin,商品名Decis,化学名称为:(1R[1a-（Sa）,3a])氰基（3-苯氧苯基）甲基3-（2,2-二溴乙烯基）-2,2-二甲基环丙烷羧酸酯。结构式:溴氰菊酯可用总溴量、红外光谱、气液色谱以及高效液相色谱（HPLC）等方法定量测

关键词：待测样品标准品超声浴标准溶液规定溶液标准物质提取溶剂原药紫外光检测器异辛烷烷烃周线制剂

The Genetic Dissection of a Short-Term.Response to Low CO_(2) Supports the Possibility for Peroxide-m.diated Decarboxylation of Photorespiratory Interm.diates in the Peroxisom.

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m.lecular Plant 2012年第6期5卷 1413-1416页

作者： Olivier Keech Wenxu Zhou Ricarda Fenske Catherine Colas-des-Francs-Sm.ll John D.Bussell m.rray R.Badger Steven m.Sm.th Centres of Excellence for Plant m.tabolom.cs and Plant Energy Biology University of Western Australia35 Stirling HighwayCrawleyWestern Australia 6009Australia UPSC Department of Plant PhysiologyUmea University90187UmeaSweden m.tabolom.cs Australia University of Western Australia35 Stirling HighwayCrawleyWestern Australia 6009Australia Centre of Excellence in Plant Energy Biology Research School of BiologyAustralian National UniversitySullivans Creek RoadActon ACT 0200Australia

Dear Editor, Photorespiration reduces plant carbon assim.lation by an estim.ted 25%-50% of net CO2 assim.lation in typical C3 plants （roussel and Igam.erdiev, 2011）. It results from.the oxygenase activity of Rubisco giving rise to phosphogly- colate. Subsequent photorespiratory m.tabolism.involves decarboxylation of glycine in the m.tochondrion and reduc- tion of hydroxypyruvate, usually assum.d to occur in the peroxisom.. Recent research in Arabidopsis has highlighted possible alternative sites of hydroxypyruvate reductase （HPR） activity （Figure 1A）. In addition to the accepted reduction by peroxisom.l HPR1, Tim. et al. （2008） identified cytosolic HPR2 and a putative chloroplast HPR3 （Tim. et al., 2011）. For HPR2 or HPR3 to function in photorespiration, hydroxypyru- vate would first need to pass from.the peroxisom. into the cytosol. Another potential fate for hydroxypyruvate is its non-enzym.c （NE） decarboxylation by reaction with hydrogen peroxide as previously suggested by experim.nts perform.d on isolated peroxisom.s （Walton and Butt, 1981）.

关键词：二氧化碳过氧化氢过氧化物酶体类核酮糖二磷酸羧化酶基因内皮缩血管肽类脱羧文化适应