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modelling the development of biological structures displaying longitudinal geometries in vitro:culturing pluripotent stem cells on plasma-treated,growth factor-coupled polycaprolactone fibres

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Engineered Regeneration 2024年第1期5卷 124-138页

作者： Badwi B.Boumelhem Stuart T.Fraser Syamak Farajikhah Rachel A.Shparberg michael B.morris marcela m.m.bilek Anyu Zhang Behnam Akhavan Simon Fleming maryanne Large School of Physics Faculty of ScienceUniversity of SydneyAustralia Sydney Nano Institute University of SydneyAustralia School of Chemical and Biomolecular Engineering University of SydneyAustralia School of medical Sciences Faculty of Medicine and HealthUniversity of SydneyAustralia School of Biomedical Engineering Faculty of EngineeringUniversity of SydneyAustralia School of Engineering University of NewcastleCallaghanNSW 2308Australia Hunter medical Research Institute(HmRI) Precision Medicine ProgramNew Lambton Heights NSW 2305Australia

many biological structures such as nerves,blood and lymphatic vessels,and muscle fibres exhibit longitudinal ge-ometries with distinct cell types extending along both the length and width of internal linear *** these three-dimensional structures in vitro is challenging:the best-defined stem-cell differentiation systems are mono-layer cultures or organoids using pluripotent stem *** stem cells can differentiate into functionally mature cells depending on the signals received,holding great promise for regenerative ***,the integration of in vitro differentiated cell types into diseased tissue remains a *** scaffolds can bridge this gap if the appropriate signalling systems are incorporated into the ***,we have taken a biomimicry approach to generate longitudinal structures in *** this approach,mouse embryonic stem cells are directed to differentiate to specific cell types on the surface of polycaprolactone(PCL)fibres treated by plasma-immersion ion implantation and to which with lineage-specifying molecules have been covalently *** demonstrate the simplicity and utility of our method for efficiently generating high yields of the following cell types from these pluripotent stem cells:neurons,vascular endothelial cells,osteoclasts,adipocytes,and cells of the erythroid,myeloid,and lymphoid *** arranged plasma-treated scaffolds with differentiated cell types could ultimately serve as a means for the repair or treatment of diseased or damaged tissue.

关键词： Pluripotent stem cells Lineage commitment Growth factors Biomaterial engineering Plasma-immersion ion implantation Covalent biomolecule attachment Polycaprolactone

电子能量损失谱及其在纳米多层膜研究中的应用

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真空科学与技术学报 2007年第6期27卷 540-544页

作者：肖晓玲代明江周克崧刘敏 D.G.mcCulloch P.C.T.Ha D.R.mckenzie m.m.m.bilek 广州有色金属研究院材料表面工程研究所广州510651 Applied Physics School of Applied SciencesRMIT University Applied and Plasma Physics School of Physics(A28)University of Sydney

本文介绍了电子能量损失谱的基本原理、能量过滤成像分析及应用电子能量损失谱计算碳同素异构体的电子密度和sp2键结构的含量。同时应用透射电镜(TEm)和电镜配置的能量过滤成像系统(gatan imaging filter),结合电子能量损失谱研究类金刚... 详细信息

本文介绍了电子能量损失谱的基本原理、能量过滤成像分析及应用电子能量损失谱计算碳同素异构体的电子密度和sp2键结构的含量。同时应用透射电镜(TEm)和电镜配置的能量过滤成像系统(gatan imaging filter),结合电子能量损失谱研究类金刚石(a-C/Ta-C)和Al/AlN两种纳米多层膜的形态、结构和膜中各元素的分布。结果显示透射电镜观察配合电子能量损失谱在纳米多层膜表征中将会扮演一个重要角色。

关键词：电子能量损失谱透射电镜纳米多层膜 a-C/Ta-C Al/AlN

添加TiO_2和ZrO_2对火焰热喷涂Al_2O_3涂层性能的影响（英文）

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Transactions of Nonferrous metals Society of China 2016年第5期26卷 1345-1352页

作者： Rassim YOUNES mohand Amokrane BRADAI Abdelhamid SADEDDINE Youcef mOUADJI Ali bilek Abderrahim BENABBAS Laboratory of mechanics Materials and Energetic Faculty of Technology University of Bejaia Laboratory of mechanics Faculty of Engineering Sciences Campus Chaabet-ErsasUniversity of Constantine mechanical Laboratory of Structure and Energetic Mechanical Engineering DepartmentUniversity of Tizi-Ouzou Laboratory Processes for materials Energy Water and Environment Faculty of Science and TechnologyUniversity of Bouira

采用火焰热喷涂技术在低碳钢表面上沉积制备添加25%ZrO_2(简称AZ-25)和3%TiO_2(简称AT-3)增强体的Al_2O_3涂层,对涂层的显微组织、相组成、显微硬度和摩擦学性能进行了研究。X射线衍射(XRD)结果表明,AT-3涂层的主要相组成为α-Al_2O_3,... 详细信息

采用火焰热喷涂技术在低碳钢表面上沉积制备添加25%ZrO_2(简称AZ-25)和3%TiO_2(简称AT-3)增强体的Al_2O_3涂层,对涂层的显微组织、相组成、显微硬度和摩擦学性能进行了研究。X射线衍射(XRD)结果表明,AT-3涂层的主要相组成为α-Al_2O_3,此外还含有一些亚稳的β-Al_2O_3和κ-Al_2O_3相。而AZ-25涂层的主要相组成为α-Al_2O_3,还有一些q-ZrO_2和m-ZrO_2相。在大多数实验条件下,AT-3涂层的摩擦学性能(摩擦因数、磨损率)均比AZ-25涂层要好。添加ZrO_2增强体会导致涂层的显微硬度降低,而添加TiO_2会使涂层硬度增加。

关键词：热喷涂涂层增强体摩擦因数磨损率

2004年12月26日苏门答腊—安达曼特大地震

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世界地震译丛 2005年第6期36卷 5-14页

作者： T.LAY H.KANAmORI C.J.AmmON m.NETTLES S.N.WARD R.C.ASTER S.L.BECK S.L.bilek m.R.BRUDZINSKI R.BUTLER H.R.DESHON G.EKSTRm K.SATAKE S.SIPKIN 石玉涛中国地震局地震预测研究所

发生在2004年12月26日（mw=9．1～9．3级）和2005年3月28日（mw=8．6级）的地震是过去40年中最大的两次地震，它们在欧亚大陆板块的东南部和印度-澳大利亚板块之间裂开一条长达1600km的断层。其中第一次地震引发的海啸吞噬了28．3万多... 详细信息

发生在2004年12月26日（mw=9．1～9．3级）和2005年3月28日（mw=8．6级）的地震是过去40年中最大的两次地震，它们在欧亚大陆板块的东南部和印度-澳大利亚板块之间裂开一条长达1600km的断层。其中第一次地震引发的海啸吞噬了28．3万多人的性命。苏门答腊岛班达亚奇附近的断层滑动了15m，但是在其北边，沿着尼科巴群岛和安达曼群岛，断层快速滑动的距离则小了很多。海啸和测地学的观测表明，在50min或更长的时间范围内北部的断层发生了更多的缓慢滑动。

关键词：苏门答腊大地震断层滑动大陆板块澳大利亚时间范围东南部测地学海啸群岛