检索结果-南通市图书馆

Heme oxygenase system in hepatic ischemia-reperfusion injury

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2010年第48期16卷 6068-6078页

作者： James A richards Stephen J Wigmore luke r Devey Centre for Inflammation research The University of EdinburghThe Queen's Medical Research Institute

Hepatic ischemia-reperfusion injury (IrI) limits access to transplantation. Heme oxygenase-1 (HO-1) is a powerful antioxidant enzyme which degrades free heme into biliverdin,free iron and carbon monoxide. HO-1 and its metabolites have the ability to modulate a wide variety of inflammatory disorders including hepatic IrI. Mechanisms of this protective effect include reduction of oxygen free radicals,alteration of macrophage and T cell phenotype. Further work is required to understand the physiological importance of the many actions of HO-1 identified experimentally,and to harness the protective effect of HO-1 for therapeutic potential.

关键词： Ischemia-reperfusion injury Heme oxygenase Transplantation Ischemic pre-conditioning

Minimising the spread of residence-time distribution for flat and heaped powders in a wedge-shaped planar hopper

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Particuology 2017年第1期15卷 102-110页

作者： luke Fullard Clive Davies Institute of Fundamental Sciences Massey University Palmerston North Campus Private Bag 11222 Palmerston North 4442 New Zealand School of Engineering and Advanced Technology Massey University Polmerston North Campus Private Bag 11222 Palmerston North 4442 New Zealand

A wedge-shaped planar mass-flow hopper system was modelled using stress-field theory as found in the literature, The authors present governing equations for stress and velocity fields under a radial- flow assumption in a converging hopper. The velocity in the silo above the hopper is modelled as plug flow, Two set-ups are modelled, one where powder layers in the hopper are assumed to be flat, and the second in which the layers are heaped at some characteristic angle, The ejection times and residence-time distributions are calculated and presented for a range of heap angles. For realistic heap angles, the spread of the residence-time distribution decreases with increasing heap angle; in one case, the spread is halved to a well-defined limit. At this limit （the critical heap angle） the geometry of the hopper can be optimised to minimise the spread of the residence-time distribution, and hence to minimise predicted mixing in the system. We present examples of curves for a variety of parameters that minimise the predicted mixing in the hopper-silo system.

关键词： residence-time distribution radial stress field Hopper Heaped layers Granular

Apologos:A Lightweight Design Method for Sociotechnical Inquiry

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Social Computing 2021年第4期2卷 297-308页

作者： luke Stark the Faculty of Information and Media Studies Western UniversityLondonN6A 0A2Canada

While scholars involved in studying the ethics and politics flowing from digital information and communication systems have sought to impact the design and deployment of digital technologies,the fast pace and iterative tempo of technical development in these contexts,and the lack of structured engagement with sociotechnical questions,have been major barriers to ensuring values are considered explicitly in the r&D *** I introduce Apologos,a lightweight design methodology informed by the author’s experience of the challenges and opportunities of interdisciplinary collaboration between computational and social sciences over a five-year ***,which is inspired by“design apologetics”,is intended as an initial mechanism to introduce technologists to the process of considering how human values impact the digital design process.

关键词： values in design values sensitive design(VSD) artificial intelligence Values@Play design methods sociotechnical ethics values

New prospects for computational hydraulics by leveraging high-performance heterogeneous computing techniques

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Hydrodynamics 2016年第6期28卷 977-985页

作者： Qiuhua LIANG luke SMITH Xilin XIA Hebei University of Engineering Handan 056038 China School of Civil Engineering and Geosciences Newcastle University Newcastle upon Tyne UK

In the last two decades, computational hydraulics has undergone a rapid development following the advancement of data acquisition and computing technologies. Using a finite-volume Godunov-type hydrodynamic model, this work demonstrates the promise of modern high-performance computing technology to achieve real-time flood modeling at a regional scale. The software is implemented for high-performance heterogeneous computing using the OpenCL programming framework, and developed to support simulations across multiple GPUs using a domain decomposition technique and across multiple systems through an efficient implementation of the Message Passing Interface （MPI） standard. The software is applied for a convective storm induced flood event in Newcastle upon Tyne, demonstrating high computational performance across a GPU cluster, and good agreement against crowd- sourced observations. Issues relating to data availability, complex urban topography and differences in drainage capacity affect results for a small number of areas.

关键词： computational hydraulics high-performance computing flood modeling shallow water equations shock-capttLring hydrodynamic model

How and why does photobiomodulation change brain activity?

在线全文

学校读者我要写书评

暂无评论

Neural regeneration research 2020年第12期15卷 2243-2244页

作者： John Mitrofanis luke AHenderson Department of Anatomy School of Medical SciencesUniversity of SydneySydneyAustralia

The concept that certain wavelengths of light can change regional brain activity as well as influencing the functional connectivity between different brain centers,is rather *** a concept goes beyond that of a function for light stimulating specialized retinal ganglion cells to entrain circadian rhythms but extends this to include light having a direct influence on all neurons to potentially influence a range of core higher-order brain *** this perspective,we explore how light may influence such core brain activities,together with why it should do so in the first place.

关键词： stimulating striking specialized

Assessment of bone charcoal dusts of six species of mammal for the postharvest control of Callosobruchus maculatus Fabricius(Coleoptera:Chrysomelidae)infestations of cowpea seeds:can the charcoal dust affect seed viability in laboratory and in field?

在线全文

学校读者我要写书评

暂无评论

Food Quality and Safety 2019年第4期3卷 279-287页

作者： luke Chinaru Nwosu Department of Crop and Soil Science University of Port HarcourtPort HarcourtRivers StateNigeria

Objectives:The possibility that bone charcoal dusts of some species of mammal will control the major insect pest of stored cowpea seeds and the implications on seed viability(after pest control process)were investigated in the laboratory at ambient temperature(30±3°C)and relative humidity(70±5%)and in *** and Methods:Standard entomological and agronomical techniques were ***:The results showed that at 1.0%w/w dosage,the bone charcoal dusts of Ovis aries and Bos taurus were more effective than permethrin standard insecticide in killing adult Callosobruchus maculatus *** cowpea seeds in *** taurus had a faster action speed than permethrin at 1.0%w/*** 1.5%w/w of dust,all the species of mammal investigated deterred oviposition considerably in *** females,whereas only the bone charcoal dusts of *** and Sus scrofa were comparable with permethrin in suppressing adult emergence and seed damage;*** only was comparable with permethrin in reducing larval *** charcoal dusts of *** and *** require chemical and olfactory analyses to know if they might have caused irritation to the insects and disrupted insect circadian rhythm,affecting behaviour and mating activities,*** bone charcoal dusts of the six species of mammal at a highest test dose of 1.5%w/w allowed high seed viability in both laboratory and ***:The study recommends the use of bone charcoal dusts of *** and *** at economical-and quality-favourable dose 1.5%w/w for managers seeking to control *** insect attacking cowpea seeds in *** transitive components of the bones,abrasion of the insect epicuticle lipid layer by the charcoal dust,and combustion-related toxic factors were responsible for the insecticidal activities of the bone charcoal dusts of the mammals.

关键词： bone charcoal dust mammal stored cowpea seed viability Callosobruchus maculatus

Maize and the maize weevil:advances and innovations in postharvest control of the pest

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Quality and Safety 2018年第3期2卷 145-152页

作者： luke Chinaru Nwosu Department of Crop and Soil Science Faculty of AgricultureUniversity of Port HarcourtP.M.B.5323Rivers StateNigeria

The review focused on recent advances and innovations on the use of maize varietal resistance and plant materials in the control of Sitophilus zeamais *** biological techniques for assessing the resistance of varieties of maize to postharvest infestation by *** were *** was suggested that routine analysis of plant species is particularly important to cope with the problem of resistance to synthetic insecticides in weevil *** the paper also revealed the important technical guidelines and scoring system for testing plant materials for insecticidal *** postharvest insect pest management strategy should form part of the overall crop husbandry for preserving the quality of the *** of resistant varieties is the best approach to overcoming the problems of synthetic insecticides in weevil ***,breeding maize crop to improve resistance against the maize weevil is associated with some technical *** limitations include lack of inter-specific cross-compatibility,methodological constraints,biotic variation,undesirable genetic linkages,and limited knowledge of genetic bases of *** screening of plant species for insecticidal activities,an untreated control and a reference insecticide whose efficacy in different agro-ecological zones is known should be designated and the plant material should be tested at economically justified *** review presented some advances and innovations on the use of maize resistance(including new formulae and scoring systems)in the control of weevil infestation and addressed maize quality and safety after pest-control *** will enhance reorientation of research focus and provide new impetus for the protection of stored maize against *** attack.

关键词： maize postharvest resistant varieties technical guides reorientation.

Transient analysis on surface heated piezoelectric semiconductor plate lying on rigid substrate

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2022年第12期43卷 1841-1856页

作者： luke ZHAO Sen GU Yaqin SONG Feng JIN State Key Laboratory for Strength and Vibration of Mechanical Structures School of Aerospace EngineeringXi'an Jiaotong UniversityXi'an 710049China

Based on the thermo-electro-elastic coupling theory,the mathematical model for a surface heated piezoelectric semiconductor(PS)plate is developed in the time *** the direct and inverse Laplace transformations to the established model,the mechanical and electrical responses are *** comparison between the analytical solution and the finite element method(FEM)is conducted,which illustrates the validity of the *** calculated results show that the maximum values of the mechanical and electrical fields appear at the heating ***,the perturbation carriers tend to concentrate in the zone near the heating surface under the given boundary *** can also be observed that the heating induced elastic wave leads to jumps for the electric potential and perturbation carrier density at the *** the thermal relaxation time is introduced,all the field quantities become smaller because of the thermal lagging ***,it can be found that the thermal relaxation time can describe the smooth variation at the jump ***,for a plate with P-N junction,the effect of the interface position on the electrical response is *** effects of the initial carrier density on the electrical properties are discussed in *** conclusions in this article can be the guidance for the design of PS devices serving in thermal environment.

关键词： thermo-electro-elastic coupling piezoelectric semiconductor(PS) surface heating transient analysis

Nonlinear analysis on electrical properties in a bended composite piezoelectric semiconductor beam

在线全文

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2023年第12期44卷 2039-2056页

作者： luke ZHAO Feng JIN Zhushan SHAO Wenjun WANG School of Science Xi’an University of Architecture and TechnologyXi’an 710055China School of Aerospace Xi’an Jiaotong UniversityXi’an 710049China MOE Key Laboratory for Multifunctional Materials and Structures School of AerospaceXi’an Jiaotong UniversityXi’an 710049China School of Science Lanzhou University of TechnologyLanzhou 730050China

In this paper,the interactions between the transverse loads and the electrical field quantities are investigated based on the nonlinear constitutive *** considering a composite beam consisting of a piezoelectric semiconductor and elastic layers,the nonlinear model is established based on the phenomenological theory and Euler’s beam ***,an iteration procedure based on the differential quadrature method(DQM)is developed to solve the nonlinear governing *** analysis,the convergence and correctness are *** is found that the convergence of the proposed iteration is ***,the transverse pressure induced electrical field quantities are investigated in *** the calculated results,it can be found that the consideration of nonlinear constitutive relation is necessary for a beam undergoing a large *** with the linear results,the consideration of the nonlinear constitutive relation breaks the symmetry for the electric potential,the electric field,and the perturbation carrier density,and has little influence on the electric ***,the non-uniform pressures are *** results show that the distributions of the electric field quantities are sensitively *** indicates that the electrical properties can be manipulated with the design of different transverse *** conclusions in this paper could be the guidance on designing and manufacturing electronic devices accurately.

关键词： nonlinear constitutive relation electrical property composite piezoelectric semiconductor beam differential quadrature method(DQM) iteration