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Sward Structural Characteristics and Performance of Beef Heifers Reared under Rotational Grazing Management on Campos Grassland

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American Journal of Plant Sciences 2014年第7期5卷 1020-1029页

作者： Cezar Wancura Barbieri fernando luiz F. de Quadros Felipe Jochims émerson Mendes Soares Leandro Bittencourt de Oliveira Régis Maximiliano R. Carvalho Gabriela machado Dutra Felipe Xavier de Lima Franciele Gusatto Natural Grassland Ecology Research Group (LEPAN-UFSM) Universidade Federal de Santa Maria Animal Science Department Santa Maria Brazil

This study aimed to evaluate the effect of two rest intervals on structural sward characteristics and productive performance of beef heifers reared on Campos grassland managed on rotational grazing. The treatments were two intervals between grazing of 375 and 750 DD (degree days), based on thermal cumulative sum for leaf expansion of native grasses belonging to two functional groups. The experimental design was a randomized complete block design with two treatments and three replications. The tested animals were beef heifers with initial age of 12 months and average weight of 185.2 ± 17.4 kg. Measures in the pasture were: herbage mass, mass of green leaf blades, stem mass, dead material mass and green leaf allowance. The 750 DD rest interval presented higher herbage mass (24%), higher green herbage mass and 19% more leaves in the canopy. This rest interval also presents a high proportion of dead material and stems in the sward structure. In the other way, the 375 DD rest interval presents better chemical characteristics, with 20% more crude protein in the hand plucking samples. Heifers’ dry matter intake was similar between the rest intervals (2.04% of live weight) and the bite mass was also similar (0.22 g DM per bite) but the animal performance was higher in the 375 DD rest interval. The stocking density showed similarity between treatments with an average of 875 kg/LW/ha. The live weight gain per area was higher in 40 kg/LW/ha (P = 0.117) for 375 DD rest interval, reaching 251 kg/LW/ha produced over the 149 experimental days. Based on these results, we can conclude that the treatment of shortest interval between defoliation gave the highest gain individual animals in warm seasons.

关键词： Average Daily Gain Duration of Leaf Expansion Herbage Mass Rotational Grazing Stocking Rate

Fecal microbiota transplantation in patients with metabolic syndrome and obesity:A randomized controlled trial

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World Journal of Clinical Cases 2023年第19期11卷 4612-4624页

作者： Alberto machado da Ponte Neto Aniele Cristine Ott Clemente Paula Waki Rosa Igor Braga Ribeiro Mateus Pereira Funari Gabriel Cairo Nunes Luana Moreira luiz Gustavo Sparvoli Ramon Cortez Carla Romano Taddei Márcio C Mancini Eduardo Guimarães Hourneaux de Moura Departament of Gastroenterology Faculdade de MedicinaUniversidade de Sao PauloServiço de Endoscopia Gastrointestinal do Hospital das Clínicas HCFMUSPSão Paulo 05403-010SPBrazil Department of Endocrinology Hospital das ClínicasUniversity of São Paulo School of MedicineSão Paulo 05403-010SPBrazil Department of Clinical and Toxicology Analysis School of Pharmaceutical SciencesUniversity of São PauloSão Paulo 05403-010SPBrazil School of Arts Science and HumanitiesUniversity of São PauloSão Paulo 05403-010SPBrazil

BACKGROUND Metabolic syndrome is a multifactorial disease,and the gut microbiota may play a role in its ***,especially abdominal obesity,is associated with insulin resistance,often increasing the risk of type two diabetes mellitus,vascular endothelial dysfunction,an abnormal lipid profile,hypertension,and vascular inflammation,all of which promote the development of atherosclerotic cardiovascular *** To evaluate the outcomes of fecal microbiota transplantation(FMT)in patients with metabolic *** This was a randomized,single-blind placebo-controlled trial comparing FMT and a sham procedure in patients with metabolic *** selected 32 female patients,who were divided into eight groups of four patients *** of the patients were submitted to upper gastrointestinal *** each group,two patients were randomly allocated to undergo FMT,and the other two patients received saline *** patients were followed for one year after the procedures,during which time anthropometric,bioimpedance,and biochemical data were *** patients also had periodic consultations with a nutritionist and an *** primary end point was a change in the gut *** There was evidence of a postprocedural change in microbiota composition in the patients who underwent FMT in relation to that observed in those who underwent the sham ***,we found no difference between the two groups in terms of the clinical parameters *** There were no significant differences in biochemical or anthropometric parameters,between the two groups ***,there were significant postprocedural differences in the microbiota composition between the placebo *** date,clinical outcomes related to FMT remain uncertain.

关键词： Fecal microbiota transplantation Metabolic syndrome Obesity Endoscopy Diabetes mellitus Endocrinology

Brain Abscess after COVID-19: Case Report

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Advances in Infectious Diseases 2023年第1期13卷 77-80页

作者： Natalia Chilinque Zambão da Silva Patrícia Yvonne Maciel Pinheiro Joao Gabriel Dib Farinhas luiz Eduardo Dalmeida machado Sampaio Fluminense Federal University Rio de Janeiro Brazil Antonio Pedro University Hospital Fluminense Federal University Rio de Janeiro Brazil Pasteur Hospital Rio de Janeiro Brazil

As the COVID-19 pandemic progresses, complications and unusual presentations of the disease have been described. Among them, the involvement of distinct parts of the neuroaxis. We report a rare case of brain abscess in elderly after SARS-Cov-2 infection readmitted in our health unit. Patient was treated with ceftriaxone, metronidazole and vancomycin with good clinical and therapeutic response. The satisfactory conduct of the case was only possible by the involvement of a multiprofessional team, which sought early diagnosis, surgical intervention and adequate duration of treatment.

关键词： Brain Abscess Biopsy COVID-19

Metabolic Parameters in Obese Dogs Undergoing to the Diet with Calorie Restriction

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Open Journal of Veterinary Medicine 2018年第3期8卷 25-35页

作者： Paula Nassar de Marchi Mauro José Lahm Cardoso Rafael Fagnani Jéssica Ragazzi Calesso Maíra Melussi luiz Henrique de Araújo machado College of Veterinary Medicine and Zootechnics Júlio de Mesquita Filho (UNESP/Botucatu) Botucatu Brazil Department of Veterinary Clinics State University of Londrina (UEL) Londrina Brazil University of North of Paraná Londrina Brazil Veterinary Hospital State University of Northern Parana (UENP/Campus Luiz Meneghel) Bandeirantes Brazil Veterinarian at Clinic Space Life (Londrina-PR) Londrina Brazil

Currently, canine obesity is a worldwide problem and is based on the excessive deposit of fat tissue, which plays an important role as a store of energy and endocrine organ. This study aimed to compare the values of systolic blood pressure, serum chemistry profile and glucose metabolism in eight obese dogs without endocrine diseases before and after 16 weeks of a weight loss program. A statistical difference was noticed in the serum levels of alkaline phosphatase, gamma glutamyl transferase, glucose, cholesterol and insulin, before and after the program. Besides, there was a statistical difference between the moments in systolic blood pressure, body weight and body condition scale. Therefore, it was concluded that the use of a diet rich in fiber and protein is suitable for performing weight loss and obese dogs undergoing a weight loss program presented a significant reduction in blood pressure, blood glucose, insulin, blood cholesterol, serum activity of alkaline phosphatase and gamma glutamyl transferase.

关键词： Arterial Hypertension Canine Insulin Resistance Obesity

Association between thrombomodulin and high mobility group box 1 in sepsis patients

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World Journal of Critical Care Medicine 2020年第4期9卷 63-73页

作者： Adriana Teixeira Rodrigues Julia Teixeira Rodrigues Carolina Teixeira Rodrigues Caroline Maria de Oliveira Volpe Fabiana Rocha-Silva Jose Augusto Nogueira-machado luiz Ronaldo Alberti Department of Pediatrics School of MedicineFederal University of Minas GeraisBelo Horizonte 30130-100Minas GeraisBrazil Graduation Program in Medicine/Biomedicine-Santa Casa Hospital-Education and Research Belo Horizonte 30150-240Minas GeraisBrazil Department of Pharmacy Federal University of Minas GeraisBelo Horizonte 31270-901Minas GeraisBrazil Department of Internal Medicine Unimed HospitalBelo Horizonte 30150-340Minas GeraisBrazil Department of Immunology Graduation Program in Medicine/Biomedicine-Santa Casa Hospital-Education and ResearchBelo Horizonte 30150-240Minas GeraisBrazil Clinical Laboratory Graduation Program in Medicine/Biomedicine-Santa Casa Hospital-Education and ResearchBelo Horizonte 30150-240Minas GeraisBrazil Department of Surgery School of MedicineFederal University of Minas GeraisBelo Horizonte 30220-000Minas GeraisBrazil

BACKGROUND High mobility group box 1(HMGB1)has been studied as a molecule associated with severe outcomes in sepsis and thrombomodulin(TM)seems to decrease HMGB1 *** To investigate the role of the thrombomodulin/high mobility group box 1(T/H)ratio in patients with sepsis and their association with their clinic,testing the hypothesis that higher ratios are associated with better *** Twenty patients diagnosed with sepsis or septic shock,according to the 2016 criteria sepsis and septic shock(Sepsis-3),were *** were followed until they left the intensive care unit or until they achieved 28 d of hospitalization(D28).The following clinical outcomes were observed:Sequential Organ Failure Assessment(SOFA)score;Need for mechanical pulmonary ventilation;Presence of septic shock;Occurrence of sepsis-induced coagulopathy;Need for renal replacement therapy(RRT);and *** The results showed that patients with SOFA scores greater than or equal to 12 points had higher serum levels of TM:76.41±29.21 pg/mL vs 37.41±22.55 pg/mL among those whose SOFA scores were less than 12 points,P=*** T/H ratio was also higher in patients whose SOFA scores were greater than or equal to 12 points,P=*** T/H ratio was,on average,three times higher in patients in need of RRT(0.38±0.14 vs 0.11±0.09),P<*** Higher serum levels of TM and,therefore,higher T/H ratio in the first 24 h after the diagnosis of sepsis were associated with more severe disease and the need for renal replacement therapy,while those with better clinical outcomes and those who were discharged before D28 showed a tendency for lower T/H ratio values.

关键词： High mobility group box 1 Sepsis Thrombomodulin Renal replacement therapy Mechanical ventilation Septic shock

Oral health of children under chemotherapy treatment

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中国口腔颌面外科杂志 2008年第B5期6卷 206-207页

作者： luiz E. R. Volpato Femanda V. Bezerra Femanda C. Ferreira Vivian B. Louzada Maria A. A. M. machado Department of Dentistry for Special Care Patients Cuiabd Dental School University of Cuiaba. Cuiaba Mato Grosso Brazil Cuiaba Dental School University of Cuiaba. Cuiaba Mato Grosso Brazil Cuiaba Dental School University of Cuiaba. Cuiaba Mato Grosso Brazil Center of Dentistry for Special Care Patients Mato Grosso State Secretary of Health. Cuiaba Mato Grosso Brazil Department of Pediatric Dentistry Orthodontics and Collective Health Bauru Dental School Sao Paulo University. Bauru Sao Paulo Brazil

Purpose: To investigate the oral health status of children under chemotherapy and the effect of the treatment for childhood malignancies on oral health and on the presence and fi'equency of oral mucosa lesions。Methods: A total of 59±29 males and 30 females mean age 9.8±2.2 years old) children affected by cancer were evaluated。The children underwent clinical and radiographic examination, were alterations in teeth and soft tissues were recorded。Results: Caries prevalence was registered, and the mean DMFT was 3.0; mean value of Gingival Index was 1.16±0.55; xerostomia was present in 22.0% of the children and spontaneous oral bleeding in 14.0%。Oral mucositis was also present in 14.0% of the children。Conclusion: Oral health of children under chemotherapy treatment for different malignancies should be carefully followed due to the fi'equent manifestations of the therapy's side effects on the oral mucosa and to the difficulties to realize an oral treatment for those children due to their systemic condition。

关键词：口腔健康儿童化学疗法治疗方法

Epidemiological Patterns of AIDS in a Reference Center from Catanduva,Sao Paulo State,Brazil

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Open Journal of Medical Microbiology 2012年第3期2卷 47-53页

作者： Arlindo Schiesari Jr. Katia Jaira Galisteu Luciana Ventura Cardoso Vanessa Maria Brogio Schiesari Adriana Antonia da Cruz Furini Andrea Regina Baptista Rossit Ricardo luiz Dantas machado Integrated College Padre Albino CatanduvaBrazil STD/AIDS Municipal Program CatanduvaBrazil Department of Dermatology Parasitic and Infectious DiseasesMedicine School in Sao Jose do Rio PretoSao Jose do Rio PretoBrazil Rio Preto University Center Sao Jose do Rio PretoBrazil Biomedical Institute Microbiology and Parasitical Diseases from Fluminense Federal UniversityNiteroiBrazil

Objective: Hereby we present the epidemiological and clinical profile of HIV-infected population before and during the highly active antiretroviral therapy (HAART) era from a tertiary care hospital in the Southeastern region of Brazil. Methods: A retrospective, cross-sectional and descriptive study was carried out, this involved the analysis of the medi-cal records of patients diagnosed with HIV-1/AIDS admitted to Hospital Escola Emílio Carlos, located in the munici-pality of Catanduva, State of S?o Paulo, Brazil. Results: In both pre-HAART and HAART periods, HIV-1 infection was more prevalent in men. Heterosexuality and secondary education were associated with AIDS in the HAART period. Statistically significant association was only observed for co-infection with HIV-1/Hepatitis C in the pre-HAART era and the number of patients with opportunistic infection (OI) was lower in the HAART period. Among all OI it is worth mentioning pulmonary pneumocystosis, which despite being common in two periods, its occurrence was considerably greater in the pre-HAART era. Concerning the distribution of OIs according to the HIV-1 viral load and serial count of T CD4+ lymphocytes, a significant association was observed. The association between the number of deaths by OIs and death in the 1st year of diagnosis in the HAART treatment was significant. Conclusions: The clinical and epidemiological profile of a specialized HIV-1/AIDS center in Catanduva, Southeastern Brazilian region, is consistent with the epidemiology of AIDS in the country.

关键词： HIV-Infected Population Antiretroviral Therapy Highly Active Brazil

Pentoxifylline improves liver regeneration through downregulation of TNF-α synthesis and TGF-β1 gene expression

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World Journal of Gastrointestinal Surgery 2012年第6期4卷 146-151页

作者： Rodrigo Bronze Martino Ana Maria Mendona Coelho Márcia Saldanha Kubrusly Regina Leito Sandra Nassa Sampietre Marcel Cerqueira Cesar machado Telesforo Bacchella luiz Augusto Carneiro D’Albuquerque Department of Gastroenterology(LIM/37) and Department of SurgeryMedical SchoolUniversity of Sao PauloSao Paulo 01246903Brazil

AIM:To investigate the mechanism of pentoxifylline(PTX)improvement in liver ***:Rats were randomized into 4 groups:Control rats;Sham-sham-operation rats;Saline-70% hepatectomy plus saline solution;PTX-70%hepatectomy plus *** 2 and 6 h after hepatectomy,aspartate aminotransferase,alanine aminotransferase,tumor necrosis factor(TNF)-α and interleukin-6(IL-6)serum and hepatic tissue levels were *** growth factor(TGF)-β1 gene expression in liver tissue was evaluated 24 h after hepatectomy by quantitative reverse transcriptase polymerase chain reaction *** was analyzed by mitotic index and proliferating cell nuclear antigen(PCNA)staining 48 h after ***:TNF-α and IL-6 serum levels increased at 2 and 6 h after *** 2 h after hepatectomy serum PTX was reduced but not hepatic levels of TNF-α and IL-6.A decrease in liver TGF-β1 gene expression and an increase in mitotic index and PCNA after hepatectomy were observed in the PTX treatment group in comparison to the saline ***:PTX improves liver regeneration by a mechanism related to down regulation of TNF-α production and TGF-β1 gene expression.

关键词： Liver regeneration Hepatectomy Pentoxifylline Tumor necrosis factor α Tumor growth factor β1

青少年乒乓运动员的焦虑和运动成绩关系(英文)

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体育科研 2005年第3期26卷 73-75页

作者： Cristina Akiko Iizuka Welber Marinovic Afonso Antonio machado luiz Henrique Porto Vilani Universidade Federal de Sao Carlos Sao Paulo BrazilUniversity of Queensland Queensland AustraliaUniversidade Estadual Paulista Sao Paulo BrazilConfederacao Brasileira de Tenis de Mesa Rio de Janeiro Brazil.

多维焦虑理论认为认知和躯体焦虑对运动成绩会产生不同的影响。根据这个理论,运动员在赛前具有较高的认知焦虑水平或躯体焦虑水平出现极端值(过高或过低)或自信心较低时,他们将取得较差的运动成绩。先前的研究还认为焦虑与运动成绩间的... 详细信息

多维焦虑理论认为认知和躯体焦虑对运动成绩会产生不同的影响。根据这个理论,运动员在赛前具有较高的认知焦虑水平或躯体焦虑水平出现极端值(过高或过低)或自信心较低时,他们将取得较差的运动成绩。先前的研究还认为焦虑与运动成绩间的关系还取决于所要完成动作的特点。不同的运动技能有各自最佳的焦虑水平。总的来说,焦虑水平较高有利于完成体力消耗较大的运动项目。而焦虑水平较低时,则有利于完成精确类项目。就乒乓球项目而言,它既需要体力又需要精确性,因此,本研究调查分析了乒乓球运动员赛前焦虑水平与运动成绩间的关系。研究对象:36 名青少年乒乓球运动员,男、女运动员各18 名,平均年龄为12.28±0.74岁。研究方法:采用运动竞赛状态焦虑量表(CSAI-2C)。让运动员在参加地区赛第一场比赛的赛前30分填写问卷。研究结果:认知状态焦虑水平不能用来预测运动员的成绩。获胜运动员和失利运动员赛前的躯体状态焦虑和自信心没有差异。这表明本研究没有支持多维焦虑理论的假设,或许是乒乓球运动的特点和运动员的个体差异比运动员的焦虑水平对运动成绩的影响更大。因此,如果运动员的个人特点与他们的技术风格相适应,不同焦虑水平的运动员都可能取得好成绩。

关键词：乒乓球焦虑运动成绩青少年运动员乒乓球