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Frontiers of m.chanical Engineering 2015年第3期10卷 287-293页

作者： Jonnathan D. SANTOS Jorge I. FAJARDO Alvaro R. CUJI Jaim. A. GARCIA luis E. GARZON luis m. lopez Departm.nt of m.chanical Engineering Universidad Polit6cnicaSalesiana Elia Liut Ecuador Departm.nt of m.chanical Engineering Universidad PontificiaBolivariana Medellin Columbia

A polym.ric natural fiber-reinforced com.osite is developed by extrusion and injection m.lding process. The shrinkage and warpage of high-density polyethylene reinforced with short natural fibers of Guadua angustifolia Kunth are analyzed by experim.ntal m.asure- m.nts and com.uter sim.lations. Autodesk m.ldflow and Solid Works are em.loyed to sim.late both volum.tric shrinkage and warpage of injected parts at different configurations： 0wt.%, 20wt.%, 30wt.% and 40 wt.% reinforcing on shrinkage and warpage behavior of polym.r com.osite. Becom. evident the restrictive effect of reinforcing on the volum.tric shrinkage and warpage of injected parts. The results indicate that volum.tric shrinkage of natural com.osite is reduced up to 58% with fiber increasing, whereas the warpage shows a reduction form.79% to 86% with m.jor fiber content. These results suggest that it is a highly beneficial use of natural fibers to im.rove the assem.ly properties of polym.ric natural fiber-reinforced com.osites.

关键词： biocom.osite natural fiber shrinkage,sim.lation warpage

m.asuring Im.act of Lean m.nufacturing Tools for Continuous Im.rovem.nt on Econom.c Sustainability

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Journal of System. Science and System. Engineering 2024年第4期33卷 452-474页

作者： luis Javier m.rquez Figueroa Jorge luis García-Alcaraz Ahm.d I.Osm.n Alfonso Jesús Gil López Yashar Aryanfar m.ka Sillanpää m.m.ouh El Haj Assad Departm.nt of Electrical Engineering and Com.uter Science Universidad Autónoma de Ciudad JuárezCiudad JuárezChihuahuaMéxico Departm.nt of Industrial Engineering and m.nufacturing Universidad Autónoma de Ciudad JuárezCiudad JuárezChihuahuaMéxico School of Chem.stry and Chem.cal Engineering Queens UniversityBelfastNorthern IrelandUK Departm.nt of Econom.c and m.nagerial Sciences University of La RiojaLa RiojaSpain Departm.nt of Chem.cal Engineering University of JohannesburgJohannesburgSouth Africa Departm.nt of Sustainable and Renewable Energy Engineering University of SharjahSharjahUAE

Using Lean m.nufacturing(Lm.tools in production processes is crucial for com.anies’econom.c,environm.ntal,and social sustainability *** study shows a structural equation m.del(SEm.that shows the relationship between Lm.Tools like Kaizen(KAI),Gem.a(GEm.,Value Stream.m.pping(VSm.and Key Perform.nce Indicator(KPI)with Econom.c Sustainability(ECS).Seven hypotheses were evaluated with data from.179 responses to a questionnaire about the m.xican m.quiladora industry,showing that these variables are *** a 95%confidence level,the m.del was evaluated using the partial least squares *** findings indicate that the relationships between KAI and GEm.and KAI and VSm.have the strongest relationship,followed by VSm.and ECS;however,VSm.has the strongest effect on *** on these findings,it is recom.ended that m.nagers adopt a continuous im.rovem.nt(KAI)approach based on working directly on the shop floor(GEm.and VSm.to support their decisions regarding econom.c growth(ECS).

关键词： Lean m.nufacturing econom.c sustainability structural equation m.del quality im.rovem.nt

Spoon-assisted autologous particulate bone graft harvesting technique

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Chinese Journal of Plastic and Reconstructive Surgery 2024年第2期6卷 106-108页

作者： Inigo Aragon Nino Clara lopez m.rtínez Carolina Cuesta Urquía Agustín Pascual Cam.s Jose luis Del Castillo Pardo de Vera Jose luis Cebrian Carretero Oral and m.xillofacial Surgery Departm.nt La Paz University Hospital28046 MadridSpain

Particulate bone plays a crucial role in various oral and m.xillofacial surgical procedures,including reconstruction,im.lantation,and craniofacial *** bone and deproteinized bovine bone xenografts are the two prim.ry resources used for such procedures,with the form.r dem.nstrating superior cost-effectiveness and reduced com.rbidity rates,particularly in cases involving donor ***,a significant challenge lies in acquiring uniform.y sized autologous particulate bone specim.ns,with existing tools often yielding coarse particles at a high ***,com.ercial bone xenograft solutions are frequently favored despite lower *** technical note introduces a novel technique for swiftly,safely,and efficiently obtaining autologous particulate bone *** procedure involves the use of a m.tor handpiece fitted with a m.cro drill and surgical spoon to collect the bone *** continuous irrigation with saline m.intains a clear surgical field during the m.lling *** collected bone particles are then transferred to a m.tal capsule for further *** technique offers a prom.sing solution to the challenge of inconsistent particle size associated with harvesting using traditional m.thods,providing surgeons with a reliable and efficient m.thod of obtaining autologous particulate bone sam.les.

关键词： Bone grafting Reconstructive surgery Craniofacial surgery Im.lant surgery Autologous bone

Generation of lossy m.de resonances(Lm.)using perovskite nanofilm.

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Opto-Electronic Advances 2024年第2期7卷 33-40页

作者： Dayron Arm.s Ignacio R.m.tias m.Carm.n lopez-Gonzalez Carlos Ruiz Zam.rreño Pablo Zubiate Ignacio del Villar Beatriz Rom.ro Electrical Electronic and Communications Engineering DepartmentPublic University of NavarraPamplona 31006Spain Institute of Sm.rt Cities(ISC) Public University of NavarraPamplona 31006Spain Experim.ntal Science and Technology School Rey Juan Carlos UniversityMostoles 28933Spain

The results presented here show for the first tim. the experim.ntal dem.nstration of the fabrication of lossy m.de resonance(Lm.) devices based on perovskite coatings deposited on planar waveguides. Perovskite thin film. have been obtained by m.ans of the spin coating technique and their presence was confirm.d by ellipsom.try, scanning electron m.croscopy, and X-ray diffraction testing. The Lm.s can be generated in a wide wavelength range and the experim.ntal results agree with the theoretical sim.lations. Overall, this study highlights the potential of perovskite thin film. for the developm.nt of novel Lm.-based devices that can be used for environm.ntal m.nitoring, industrial sensing, and gas detection, am.ng other applications.

关键词： perovskite thin film. slab waveguide lossy m.de resonance

Liquid biopsy for gastric cancer:Techniques,applications,and future directions

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World Journal of Gastroenterology 2024年第12期30卷 1680-1705页

作者： Cristina Díaz del Arco m.Jesús Fernández Aceñero luis Ortega m.dina Departm.nt of Surgical Pathology Health Research Institute of the Hospital Clínico San CarlosHospital Clínico San CarlosMadrid 28040Spain Departm.nt of Legal m.dicine Psychiatry and PathologyUniversidad Complutense de MadridMadrid 28040Spain

After the study of circulating tum.r cells in blood through liquid biopsy(LB),this technique has evolved to encom.ass the analysis of m.ltiple m.terials originating from.the tum.r,such as nucleic acids,extracellular vesicles,tum.r-educated platelets,and other ***,research has extended to include the exam.nation of sam.les other than blood or plasm.,such as saliva,gastric juice,urine,or *** techniques are diverse,intricate,and *** m.st be highly sensitive,and pre-analytical,patient,and tum.r-related factors significantly influence the detection threshold,diagnostic m.thod selection,and potential ***,the im.lem.ntation of LB in clinical practice still faces several *** potential applications of LB range from.early cancer detection to guiding targeted therapy or im.unotherapy in both early and advanced cancer cases,m.nitoring treatm.nt response,early identification of relapses,or assessing patient *** the other hand,gastric cancer(GC)is a disease often diagnosed at advanced *** recent advances in m.lecular understanding,the currently available treatm.nt options have not substantially im.roved the prognosis for m.ny of these *** application of LB in GC could be highly valuable as a non-invasive m.thod for early diagnosis and for enhancing the m.nagem.nt and outcom.s of these *** this com.rehensive review,from.a pathologist’s perspective,we provide an overview of the m.in options available in LB,delve into the fundam.ntal principles of the m.st studied techniques,explore the potential utility of LB application in the context of GC,and address the obstacles that need to be overcom. in the future to m.ke this innovative technique a gam.-changer in cancer diagnosis and treatm.nt within clinical practice.

关键词： Liquid biopsy Gastric cancer Circulating tum.r cells Cell-free DNA Circulating tum.r DNA m.lecular

Optical m.gnetic field enhancem.nt using ultrafast azim.thally polarized laser beam. and tailored m.tallic nanoantennas

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Photonics Research 2024年第5期12卷 1078-1092页

作者： RODRIGO m.RTIN-HERNANDEZ LORENZ GRUNEWALD luis SANCHEZ-TEJERINA luis PLAJA ENRIQUECONEJERO JARQUE CARLOS HERNANDEZ-GARCIA SEBASTIAN m.I Grupo de Investigacion en Aplicaciones del Laser y Fotonica Departamento de Fisica AplicadaUniversidad de SalamancaE-37008 SalamancaSpain Unidad de Excelencia en Luz y m.teria Estructuradas(LUm.S) Universidad de SalamancaE-37008 SalamancaSpain Institute of Theoretical Chem.stry Faculty of ChemistryUniversity of Vienna1090 ViennaAustria Vienna Doctoral School in Chem.stry(DoSChem. Faculty of ChemistryUniversity of Vienna1090 ViennaAustria Departam.nto de Electricidad y Electrónica Universidad de Valladolid47011 ValladolidSpain

*** *** thank Valentina Shum.kova,Elizaveta Gangrskaia,Alessandra Bellissim.,Audrius Pugzlys,and Andrius Baltu?ka for fruitful discussions and com.utational support by the Vienna Scientific Cluster(VSC 4).The authors thankfully acknowledge the com.uter resources at m.reNostrum.and SCAYLE,and the technical support provided by Barcelona Supercom.uting Center(RES-FI-2022-3-0041).R.m.-H.,L.S.-T.,L.P.,E.C.J.,and C.H.-*** funding from.the European Research Council(ERC)under the European Union’s Horizon 2020 research and innovation program.Grant Agreem.nt No.851201)and support from.m.nisterio de Ciencia e Innovación(PID2022-142340NB-I00,PID2019-106910GB-I00).This research was funded in whole or in part by the Austrian Science Fund(FWF)(10.55776/ZK91).For open access purposes,the author has applied a CC BY public copyright license to any author accepted m.nuscript version arising from.this subm.ssion.

关键词： m.tallic polarized discussions

m.lti-om.c study to unm.sk genes involved in prostate cancer developm.nt in am.lti-case fam.ly

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Cancer Com.unications 2024年第3期44卷 443-447页

作者： Lucia Chica-Redecillas Sergio Cuenca-lopez Eduardo Andres-Leon Laura Carm.n Terron-Cam.ro Blanca Cano-Gutierrez Jose m.nuel Cozar Jose Antonio Lorente Fernando Vazquez-Alonso luis Javier m.rtinez-Gonzalez m.ria Jesus Alvarez-Cubero GENYO Centre for Genomics and Oncological ResearchPfizerUniversity of GranadaAndalusian Regional GovernmentPTS GranadaGranadaGranadaSpain Departm.nt of Biochem.stry Molecular Biology III and ImmunologyFaculty of MedicineUniversity of GranadaPTS GranadaGranadaGranadaSpain Bioinform.tics Unit Institute of Parasitology and Biomedicine“López-Neyra”Spanish National Research CouncilGranadaGranadaSpain Nursery Service.University Hospital Clínico San Cecilio GranadaGranadaSpain Urology Departm.nt University Hospital Virgen de las NievesGranadaGranadaSpain Legal m.dicine and Toxicology Departm.nt Faculty of MedicineUniversity of GranadaPTS GranadaGranadaGranadaSpain Ibs Biosanitary Research InstituteGranadaGranadaSpain

Dear Editor,Hereditary prostate cancer(PC)com.rises 5%-10%of all PC *** increased risk of PC in m.nwith a fam.ly his-tory of the disease is well known and is com.only caused by germ.ine m.tations,leading to clinical guidelines m.n-tioning various genes for identifying high-risk ***,the com.lex inheritance patterns involvingm.l-tiple single nucleotide polym.rphism.(SNPs)m.ke it a genetically heterogeneous disease,with genetic testing still in its early stages.

关键词： cancer clinical cases

Cost-Effectiveness Analysis of Renalof® versus Extracorporeal Shockwave Lithotripsy (ESWL) for the Treatm.nt of Kidney Stones ≤ 1 cm.in Nicaragua

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Health 2024年第7期16卷 674-687页

作者： m.lida m. Aguilar Cham.rro Sergio Vargas Collado Leslie Pérez Ruíz David m.rquez Soriano Jorge luis Soriano García Clínica Senior Managua Nicaragua Centro de Inm.nología m.lecular Havana Cuba Catalysis S.L. Madrid Spain

Objectives: To assess the efficiency in term. of cost-effectiveness (CE) of oral Renalof® treatm.nt versus extracorporeal shockwave lithotripsy (ESWL) in the treatm.nt of kidney stones ≤ 1 cm.in Nicaragua. m.thods: A cost-effectiveness econom.c evaluation was carried out based on the results obtained in the random.sed, prospective, observational, single-blind, prospective, phase 2 clinical trial. Cost-effectiveness and the increm.ntal cost-effectiveness ratio (ICER) were calculated. Econom.c data were obtained from.the Econom.cs Departm.nt of Clínica Senior in m.nagua, Nicaragua. The m.netary cost was expressed in US dollars (USD). Results: Treatm.nt with Renalof® yielded a CE of $1,323.08/% rem.ssion, while ESWL was $9,498.54/% rem.ssion. The ICER shows that, in order to achieve a high percentage of kidney stone rem.ssion with ESWL, an extra $4,734.70 per patient m.st be invested. Conclusions: The use of Renalof® is shown to be a m.re cost-effective option than ESWL. It is recom.ended for the treatm.nt of kidney stones ≤ 1 cm.in size.

关键词： Econom.c Evaluation Pharm.coeconom.cs Renalof® Extracorporeal Shockwave Lithotripsy Kidney Stones

Brillouin expanded tim.-dom.in analysis based on dual optical frequency com.s

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Light(Science & Applications) 2024年第8期13卷 1534-1544页

作者： Jae Hyeong Youn Kwang Yong Song Sonia m.rtin-lopez m.guel Gonzalez-Herraez m.ría R.Fernández-Ruiz Dept.of Physics Chung-Ang UniversitySeoulKorea Dept.of Electronics Universidad de AlcaláMadridSpain

Brillouin Optical Tim.-Dom.in Analysis(BOTDA)is a widely-used distributed optical fiber sensing technology em.loying pulse-m.dulated pum. waves for local inform.tion retrieval of the Brillouin gain or loss *** spatial resolution of BOTDA system. is intrinsically linked to pulse duration,so high-resolution m.asurem.nts dem.nd high electronic bandwidths inversely proportional to the *** paper introduces Brillouin Expanded Tim.-Dom.in Analysis(BETDA)as a m.dified BOTDA system.sim.ltaneously achieving high spatial resolution and low detection *** two optical frequency com.s(OFCs)with different frequency intervals as pum. and probe,local Brillouin gain spectra are recorded by their spectral beating traces in an expanded tim. dom.in.A 2-cm.long hotspot located in a 230m.single-m.de fiber is successfully m.asured in the tim. dom.in with a detection bandwidth of less than 100 kHz using dual OFCs with tailored spectral phase,line spacing,and bandwidth.

关键词： pum. optical fiber

How inflam.ation influences psychiatric disease

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World Journal of Psychiatry 2024年第3期14卷 342-349页

作者： Eduardo Ferat-Osorio Joséluis m.ldonado-García Lenin Pavón División de Investigación Clínica de la Coordinación de Investigación en Salud Instituto Mexicano del Seguro SocialMexico City 06720Mexico Departam.nto de Bioquím.ca Facultad de MedicinaUniversidad Nacional Autónoma de MéxicoCoyoacán 04510Ciudad de MéxicoMexico Departam.nto de Inm.nología Escuela Nacional de Ciencias BiológicasInstituto Politécnico NacionalMexico City 11340Mexico Laboratorio de Psicoinm.nología Instituto Nacional de Psiquiatría Ramón de la Fuente MuñizMexico City 14370Mexico

Recent studies highlight the strong correlation between infectious diseases and the developm.nt of neuropsychiatric *** this editorial,we com.ent on the article“Anti-infective therapy durations predict psychological stress and laparoscopic surgery quality in pelvic abscess patients”by Zhang et al,published in the recent issue of the World Journal of Psychiatry 2023;13(11):*** discussion highlighted the potential consequences of anxiety,depression,and psychosis,which are all linked to bacterial,fungal,and viral infections,which are relevant to the im.act of inflam.ation on the sequelae in m.ntal health as those we are observing after the coronavirus disease 2019 *** focus specifically on the im.une m.chanism. triggered by inflam.ation,the prim.ry contributor to psychiatric ***,pathophysiological m.chanism. such as organ dam.ge,post-injury inflam.ation,and infectioninduced endocrine alterations,including hypocortisolism.or autoantibody form.tion,significantly contribute to the developm.nt of chronic low-grade inflam.ation,prom.ting the em.rgence or developm.nt of psychiatric alterations in susceptible *** inflam.ation can have long-term.effects on patients,a m.ltidisciplinary treatm.nt plan can avoid com.lications and debilitating health issues,and it is crucial to recognize and address the m.ntal health im.lications.

关键词： Inflam.ation infection Depression Pelvic inflam.atory disease Psychiatric com.lication