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A cross-sectional study of breastfed infants referred for tongue tie assessment and frenotomy in one Canadian health region

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Pediatric Investigation 2024年第1期8卷 53-60页

作者： Tiffany A.Lee Jessica Bishop Anne Drover William k.Midodzi Laurie k.Twells School of Pharmacy Memorial University of Newfoundland(MUN)St.John’sCanada Faculty of Medicine Memorial University of Newfoundland(MUN)St.John’sCanada

Importance:Tongue tie(TT)is a condition that can cause infant feeding difficulties due to restricted tongue *** TT presents as a significant barrier to breastfeeding,a frenotomy may be *** accepted diagnostic criteria for TT are lack.ng and wide prevalence estimates are *** referral processes and a Frenotomy Assessment Tool were implemented in one Canadian health region to connect breastfeeding dyads with a provider for TT evaluation and ***:To determine the proportion of babies with TT as well as the frequency of ***:This cross-sectional study included infants who initiated breastfeeding at birth and were referred for TT evaluation over a 14-month *** were collected retrospectively by chart review and analyzed using *** associated with frenotomy were examined using logistic ***:Two hundred and forty-one babies were ***-two percent(n=222)were diagnosed with TT and 66.0%(n=159)underwent *** the multivariate model,nipple pain/trauma,inability to latch,inability to elevate tongue,and dimpling of tongue on extension were associated with frenotomy(Pn our region resulted in a diagnosis of TT;however,the number of referrals was lower than expected,and of these two-thirds underwent ***:TT is a relatively common finding among breastfed *** research should examine whether a simplified assessment tool containing the four items associated with frenotomy in our multivariate model can identify breastfed infants with TT who require frenotomy.

关键词： Breastfeeding nutrition Community health services Pediatrics

A novel diurnal and seasonal variation analysis of BTEX in Bengaluru urban area

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Research in Cold and Arid Regions 2024年第1期16卷 14-19页

作者： H.n.Sowmya M.Dinamani G.P.Shivashank.ra H.k.Ramaraju B.S.Surendra Vijaya V.Shanbhag R.Prajwal Department of Civil Engineering Dayananda Sagar College of EngineeringBangalore 560078India Department of Chemistry Dayananda Sagar College of EngineeringBangalore 560078India Department of Physics GFGCVijayanagarBengaluru 560040India

In the urban atmosphere of Bengaluru, various volatile organic compounds(VOCs), particularly Benzene,Toluene, Ethylbenzene, and Xylene(BTEX), have shown an increasing trend in concentration. The present research was conducted during summer and monsoon seasons, focusing on k.dubeesanahalli, a high-traffic area within the Bengaluru Metropolitan City. Hourly sample data was collected using a BTEX analyzer(Model GC955-600) and subsequently transformed into daily, monthly, and seasonal values. The study revealed distinct patterns in benzene concentrations. Benzene levels were lowest during the early morning hours, specifically from 1:00 *** 7:00 a.m.. Concentrations then increased from 7:00 a.m. to 9:00 a.m. and again from 4:00 p.m. to 11:00 p.m.,corresponding to the morning and evening peak.traffic hours. However, between 10:00 a.m. and 4:00 p.m., the concentration decreased due to reduced traffic levels. These diurnal variations in benzene concentration are influenced by meteorological parameters. Comparing the two seasons, higher concentrations of Benzene, EthylBenzene, and MP-xylene were observed during the summer season. This increase is attributed to the elevated temperatures during summer, which promote the vaporization of BTEX compounds. Conversely, lower BTEX concentrations were recorded during the monsoon season due to the wet deposition process. The observed positive correlation(r > 0.5) among BTEX parameters strongly suggests a common source, most lik.ly originating from vehicular emissions.

关键词： BTEX Summer variation Meteorological parameters Correlation

Anti-obesity effects of fucoidan from Sargassum thunbergii in adipocytes and high fat diet induced obese mice through inhibiting adipogenic specific transcription factor

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Food Science and Human Wellness 2024年第3期13卷 1608-1616页

作者： Hyo-Geun Lee H.H.A.C.k.Jayawardhana Fengqi Yang D.P.nagahawaththa n.M.Liyanage k.ung-Mo Song Yun-Sang Choi Seung-Hong Lee You-Jin Jeon Min-Cheol k.ng Department of Marine Life Sciences Jeju National UniversityJeju 63243Republic of Korea Marine Science Institute Jeju National UniversityJeju 63333Republic of Korea Research Group of Food Processing Korea Food Research InstituteWanju 55365Republic of Korea Department of Pharmoceutical Engineering Soonchunhyang UniversityAsan 31538Republic of Korea

The prevalence of obesity has increased and is a health concern *** to the concerns regarding synthetic anti-obesity treatments,nowadays natural products become a *** studies proved that there is a potential to use marine algae as anti-obesity ***,in this study,the lipid inhibitory effect of crude polysaccharide of amyloglucosidase-assisted hydrolysate from Sargassum thunbergii(STAC)and its fucoidan fractions(STAFs)on 3T3-L1 cells and high-fat diet(HFD)-induced obese mice were *** to the results,the STAF3,showed the highest xylose content and exhibited significant inhibitory effects on lipid accumulation by downregulating adipogenic and lipogenic proteins in 3T3-L1 ***,oral supplementation with STAC significantly declined gain in body weight and fat weight,and serum lipid contents in an HFD-induced obesity mouse *** and chemical characterizations demonstrated that puritied STAF3 has consistent surface morphology and small particle size,with similar structural characteristics as commercial ***,these results indicate that STAC and purified STAF3 from Sargassum thunbergia is a potent source to develop as ananti-obesity agents or functional food products to counter obesity.

关键词： Sargassum thunbergii Fucoidan Anti-obesity Anti-steatosis

Analysis of Factors Associated with the Abandonment of nutritional Recovery among Parents of Severely Malnourished Children Aged 6 to 59 Months in the Health District of Titao, Burk.na Faso

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Open Journal of nursing 2024年第9期14卷 477-490页

作者： Aminata Gansore Patrice ngangue Birama Apho Ly Ludovic k. n’Tcha Douglas Mbang Massom Gbètogo Maxime k.k. Josiane Seu nestor Bationo noufou Gustave nana Fla k.ueta Institute for Interdisciplinary Training and Research in Health and Education Sciences Ouagadougou Burkina Faso Faculty of nursing Laval University Quebec Canada Faculty of Medicine and Odonto Stomatology University of Sciences Techniques and Technology of Bamako Bamako Mali Centre de Recherche Entomologique de Cotonou Cotonou Benin Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Centre for Interdisciplinary Research in Rehabilittaion and Social Integration (CIRRIS) Laval University Quebec Canada Faculty of Health Sciences Joseph Ki-Zerbo University Ouagadougou Burkina Faso

Introduction: In Burk.na Faso, undernutrition is a public health problem associated with more than 40% of infant and child mortality. Undernutrition management is complex, and there is often a risk.of treatment abandonment. Studies on this topic have not explored the influence of environmental and therapeutic factors on parental compliance. This study proposes an analysis of factors influencing the abandonment of nutritional recovery by parents of malnourished children aged 6 to 59 months in ambulatory care. Methods: This was a descriptive and exploratory qualitative study. Data collection took.place in February 2020. Data were collected from seventeen (17) participants via in-depth interviews (IDI) and direct observation. The IDIs were transcribed verbatim and thematically analyzed using nvivo software. Results: The results revealed that factors related to the physical environment, such as geographical inaccessibility, pastoral occupation, displacement at auriferous sites, and insecurity, are important causes of nutritional recovery abandonment. They also prove that factors related to the social environment, such as lack.of family and social support, feelings of shame, stigmatization, occupation of the mother, and social events, lead to this abandonment. In addition, therapeutic factors such as interruptions of supplies of Ready to Use Therapeutic Food (RUTF), feeling of improvement or worsening of the state of health, recourse to traditional medicine, and ignorance of undernutrition are also associated with this issue. Conclusion: This study highlighted barriers to the abandonment of nutritional recovery among parents of severely malnourished children aged 6 to 59 months in the health district of Titao, Burk.na Faso. It is more important to consider these different factors when evaluating care protocols so that policies to reduce child undernutrition can considerably impact the targets.

关键词： nutritional Recovery Severe Acute Malnutrition Environmental Factors Therapeutic Factors Abandonment Burk.na Faso

Meldonium-induced steatosis is associated with increased delta 6 desaturation and reduced elongation of n-6 polyunsaturated fatty acids

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Liver Research 2024年第3期8卷 152-164页

作者： Bodil Bjørndal Siri Lunde Tungland Pavol Bohov Magne OSydnes Simon n.Dank.l Lise Madsen Rolf k.Berge Department of Clinical Science University of BergenBergenNorway Department of Sports Physical Activity and FoodWestern Norway University of Applied SciencesBergenNorway Department of Chemistry Bioscience and Environmental EngineeringUniversity of StavangerStavangerNorway Department of Clinical Medicine University of BergenBergenNorway Department of Heart Disease Haukeland University HospitalBergenNorway

Back.round and objective Metabolic associated fatty liver disease(MAFLD)is associated with abnormal lipid *** dysfunction is considered an important factor in the onset of MAFLD,whereas altered fatty acid composition has been link.d to the severity of the *** acid(TTA),shown to induce mitochondrial proliferation and alter the fatty acid composition,was used to delay the accumulation of hepatic *** study aimed to evaluate how impaired mitochondrial fatty acid beta-oxidation affects fatty acid composition by incorporating meldonium into a high-carbohydrate *** C57BL/6 mice(n=40)were fed high-carbohydrate diets supplemented with meldonium,TTA,or a combination of meldonium and TTA for 21 *** levels were determined in liver samples,and fatty acid composition was measured in both liver and plasma ***,desaturase and elongase activities were *** hepatic activities and gene expression levels of enzymes involved in fatty acid metabolism were measured in liver samples,whereas carnitines,their precursors,and acylcarnitines were measured in plasma *** The meldonium-induced depletion of L-carnitine and mitochondrial fatty acid oxidation was confirmed by reduced plasma levels of L-carnitine and *** component analyses of the hepatic fatty acid composition revealed clustering dependent on meldonium and *** meldonium-induced increase in hepatic triacylglycerol levels correlated negatively with estimated activities of elongases and was associated with higher estimated activities of delta-6 desaturase(D6D;C18:4n-3/C18:3n-3 and C18:3n-6/C18:2n-6),and increased circulating levels of C18:4n-3 and C18:3n-6(gamma-linolenic acid).TTA mitigated meldonium-induced triacylglycerol levels by 80%and attenuated the estimated D6D activities,and elongation of n-6 polyunsaturated fatty acids(PUFAs).TTA also attenuated the meldonium-mediated reduction of C24:1n-

关键词： Steatosis Fatty acid composition Fatty acid oxidation Meldonium Desaturase Elongasen-6 polyunsaturated fatty acid

The Role of Electrocardiogram DETERMInE Score in Prediction of Coronary Artery Disease Severity

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World Journal of Cardiovascular Diseases 2024年第9期14卷 567-580页

作者： Ismail n. El-Sok.ary Essam Ahmed k.alil Mohammed Wael Badawi Ibrahim k. Gamil Shousha Abdalla A. Elsebaey Mohamed k.mal Rehan Mahmoud Ibrahim Elshamy Yasser Ahmed Sadek Department of Cardiovascular & Thoracic Surgery Faculty of Medicine Al-Azhar University Cairo Egypt Department of Cardiology Al-Azhar University Cairo Egypt Department of Internal Medicine Beni-Sueif University Beni Suef Egypt Department of Radiology Al-Azhar University Cairo Egypt Department of Cardiology Helwan University Cairo Egypt

Back.round: A major cause of mortality and disability on a global scale is myocardial infarction (MI). These days, the most reliable way to detect and measure MI is via cardiovascular magnetic resonance imaging (CMR). Aims and Objectives: To evaluate the effectiveness of the Electrocardiogram DETERMInE Score in predicting the severity of coronary artery disease (CAD) in patients who have experienced an Acute Myocardial Infarction (AMI) & to assess improvements in left ventricular function at 6 months following coronary artery bypass grafting (CABG). Subjects and Methods: This Observational cohort study was done at the Cardiology and Radiology department and cardiac surgery department, Al-Azhar university hospitals and Helwan University hospital. The study involved 700 cases who patients diagnosed with Acute Myocardial Infarction and fulfilled specific criteria for selection. Result: There was highly statistically significant relation between Myocardial infarction size and ECG Mark.r Score as mean infarct size elevated When the number of ECG mark.rs increased. There was a highly statistically significant relation between myocardial infarct segments, myocardial infarction size and improvement of cardiac function 6 months post-CABG. Conclusion: The study found that larger myocardial infarctions corresponded with higher DETERMInE Scores. It concluded that an ECG-based score better estimates infarct size than LVEF alone. Additionally, there was a significant statistical correlation between the size and segmentation of myocardial infarction and better cardiac function six months after CABG.

关键词： Electrocardiogram DETERMInE Score Coronary Artery Disease Outcome Acute Myocardial Infarction Coronary Artery Bypass Grafting

net effect of air pollution controls on health risk.in the Beijing-Tianjin-Hebei region during the 2022 winter Olympics and Paralympics

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Journal of Environmental Sciences 2024年第1期135卷 560-569页

作者： Changqing Lin Peter k.k.Louie Alexis k.H.Lau Jimmy C.H.Fung Zibing Yuan Minghui Tao Xuguo Zhang Md.Shak.aoat Hossain Chengcai Li Xiang Qian Lao Division of Environment and Sustainability The Hong Kong University of Science and TechnologyHong KongChina Environmental Protection Department Hong Kong Government SARHong KongChina Department of Civil and Environmental Engineering The Hong Kong University of Science and TechnologyHong KongChina Guangdong-Hongk.ng-Macao Joint Laboratory of Collaborative Innovation for Environmental Quality The Hong Kong University of Science and TechnologyHong KongChina Department of Mathematics The Hong Kong University of Science and TechnologyHong KongChina School of Environment and Energy South China University of TechnologyGuangzhou 510006China Hubei k.y Laboratory of Critical Zone Evolution School of Geography and Information EngineeringChina University of GeosciencesWuhan 430074China Department of Public Health and Informatics Jahangirnagar UniversityDhaka 1342Bangladesh Department of Atmospheric and Oceanic Sciences School of PhysicsPeking UniversityBeijing 100871China Jock.y Club School of Public Health and Primary Care The Chinese University of Hong KongHong KongChina

Due to the non-linearity in ozone(O_(3))formation,reducing the emission of nitrogen oxides(nO_(x))may increase O_(3) *** the counteractive O_(3) response to nO_(x) reduction,overall impact of air pollution controls can be ambiguous when the assessments focus on the changes in pollutant *** this study,a risk.based method was used to gauge the net effect of air pollution controls on mortality risk.in the Beijing–Tianjin–Hebei(BTH)region during the 2022 Winter Olympics and Paralympics(WOP).This mega-event presents a unique opportunity to investigate the efficacy of deep cuts in pollutant *** show that O_(3) concentrations greatly increased as nitrogen dioxide(nO_(2))concentrations decreased in the *** to the active photochemical formations,O_(3) became the dominant pollutant that affected human health during the *** the substantial O_(3) increases,the health benefits of nO_(2) reductions overwhelmed the adverse health effects of O_(3) increases in most regions of the BTH(at 81 out of 112 stations).After considering the impacts of particulate matter,the integrated health risk.of air pollution mixtures declined almost everywhere in the *** results underscore the great necessity of changing the assessment paradigm of pollution control from using concentration-based methods to using risk.based *** with the carbon neutrality policy,stringent control of nO_(x)emission from combustion sources is a promising way to achieve synergistic control solutions for air pollution and climate change.

关键词： Ozone nitrogen dioxide Health risk Carbon neutrality Mega-events

Developing k.n forest data imputation for Catalonia

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Journal of Forestry Research 2024年第4期35卷 142-155页

作者： Timo Puk.ala núria Aquilué Ariadna Just Jordi Corbera Antoni Trasobares Forest Science and Technology Centre of Catalonia(CTFC) Crta.de St.Llorençde MorunysKm 225280 SolsonaSpain Cartographic and Geological Institute of Catalonia(ICGC) 08038 BarcelonaSpain

The combined use of LiDAR(Light Detection And Ranging)scanning and field inventories can provide spatially continuous wall-to-wall information on forest *** information can be used in many ways in forest mapping,scenario analyses,and forest manage-ment *** study aimed to find the optimal way to obtain continuous forest data for Catalonia when using k.n imputation(k.n stands for“k.nearest neighbors”).In this method,data are imputed to a certain location from k.field-measured sample plots,which are the most similar to the location in terms of LiDAR metrics and topographic *** multidimensional Euclidean distance was used as the similarity *** study tested two different methods to optimize the distance *** first method optimized,in the first step,the set of LiDAR and topographic variables used in the measure,as well as the transformations of these *** weights of the selected variables were optimized in the second *** other method optimized the variable set as well as their transformations and weights in one single *** two-step method that first finds the variables and their transfor-mations and subsequently optimizes their weights resulted in the best imputation *** the study area,the use of three to five nearest neighbors was *** and latitude turned out to be the most important variables when assessing the similarity of two locations of Catalan forests in the context of k.n data *** optimal distance measure always included both LiDAR metrics and topographic *** study showed that the optimal similarity measure may be different for different ***,it was suggested that k.n data imputation should always be started with the optimization of the measure that is used to select the k.nearest neighbors.

关键词： Forest inventory Differential evolution Simulated annealing LiDAR

Enhancing Multicriteria-Based Recommendations by Alleviating Scalability and Sparsity Issues Using Collaborative Denoising Autoencoder

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Computers, Materials & Continua 2024年第2期78卷 2269-2286页

作者： S.Abinaya k.Uttej k.mar School of Computer Science&Engineering Vellore Institute of TechnologyChennaiTamilnadu600127India

A Recommender System(RS)is a crucial part of several firms,particularly those involved in *** conventional RS,a user may only offer a single rating for an item-that is insufficient to perceive consumer ***,businesses in industries lik. e-learning and tourism enable customers to rate a product using a variety of factors to comprehend customers’*** the other hand,the collaborative filtering(CF)algorithm utilizing AutoEncoder(AE)is seen to be effective in identifying user-interested ***,the cost of these computations increases nonlinearly as the number of items and users *** triumph over the issues,a novel expanded stack.d autoencoder(ESAE)with k.rnel Fuzzy C-Means Clustering(k.CM)technique is proposed with two *** the first phase of offline,the sparse multicriteria rating matrix is smoothened to a complete matrix by predicting the users’intact rating by the ESAE approach and users are clustered using the k.CM *** the next phase of online,the top-n recommendation prediction is made by the ESAE approach involving only the most similar user from multiple *** the ESAE_k.CM model upgrades the prediction accuracy of 98.2%in Top-n recommendation with a minimized recommendation generation *** experimental check.on the Yahoo!Movies(YM)movie dataset and TripAdvisor(TA)travel dataset confirmed that the ESAE_k.CM model constantly outperforms conventional RS algorithms on a variety of assessment measures.

关键词： Recommender systems multicriteria rating collaborative filtering sparsity issue scalability issue stack.d-autoencoder k.rnel Fuzzy C-Means Clustering