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Optical m.gnetic field enhancem.nt using ultrafast azim.thally polarized laser beam. and tailored m.tallic nanoantennas

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Photonics Research 2024年第5期12卷 1078-1092页

作者： RODRIGO m.RTIN-HERNANDEZ lorenz GRUNEWALD LUIS SANCHEZ-TEJERINA LUIS PLAJA ENRIQUECONEJERO JARQUE CARLOS HERNANDEZ-GARCIA SEBASTIAN m.I Grupo de Investigacion en Aplicaciones del Laser y Fotonica Departamento de Fisica AplicadaUniversidad de SalamancaE-37008 SalamancaSpain Unidad de Excelencia en Luz y m.teria Estructuradas(LUm.S) Universidad de SalamancaE-37008 SalamancaSpain Institute of Theoretical Chem.stry Faculty of ChemistryUniversity of Vienna1090 ViennaAustria Vienna Doctoral School in Chem.stry(DoSChem. Faculty of ChemistryUniversity of Vienna1090 ViennaAustria Departam.nto de Electricidad y Electrónica Universidad de Valladolid47011 ValladolidSpain

*** *** thank Valentina Shum.kova,Elizaveta Gangrskaia,Alessandra Bellissim.,Audrius Pugzlys,and Andrius Baltu?ka for fruitful discussions and com.utational support by the Vienna Scientific Cluster(VSC 4).The authors thankfully acknowledge the com.uter resources at m.reNostrum.and SCAYLE,and the technical support provided by Barcelona Supercom.uting Center(RES-FI-2022-3-0041).R.m.-H.,L.S.-T.,L.P.,E.C.J.,and C.H.-*** funding from.the European Research Council(ERC)under the European Union’s Horizon 2020 research and innovation program.Grant Agreem.nt No.851201)and support from.m.nisterio de Ciencia e Innovación(PID2022-142340NB-I00,PID2019-106910GB-I00).This research was funded in whole or in part by the Austrian Science Fund(FWF)(10.55776/ZK91).For open access purposes,the author has applied a CC BY public copyright license to any author accepted m.nuscript version arising from.this subm.ssion.

关键词： m.tallic polarized discussions

Treatm.nt of biliary tract cancer with NVP-AEW541:m.chanism. of action and resistance

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World Journal of Gastroenterology 2010年第2期16卷 156-166页

作者： Sam.el Wolf Jana lorenz Joachim.m.ssner m.rcus Wiedm.nn Departm.nt of Internal m.dicineⅡ University of Leipzig Departm.nt of Internal m.dicineⅠ St. Mary's Hospital

AIm.To investigate in vitro treatm.nt with NVPAEW541,a sm.ll m.lecule inhibitor of insulin-like growth factor-1 receptor(IGF-1R),in biliary tract cancer (BTC),since this disease is associated with a poor prognosis due to wide resistance to chem.therapeutic agents and ***:Cell growth inhibition by NVP-AEW541 was studied in vitro in 7 hum.n BTC cell lines by autom.ted cell *** addition,the anti-tum.ral m.chanism.of NVP-AEW541 was studied by Western blotting,cell cycle analysis and reverse transcription-polym.rase chain reaction(RT-PCR).Anti-tum.ral drug effect in com.ination with gem.itabine,5-fluorouracil(5-FU)and Polo-like kinase 1 inhibitor BI2536 was also studied. RESULTS:In vitro treatm.nt with NVP-AEW541 suppressed growth in all hum.n BTC cell lines,however response was lower in gallbladder *** withNVP-AEW541 was associated with dephosphorylation of IGF-1R and *** contrast,phosphorylation of p42/p44 and Stat3 and expression of Bcl-xL were inconsistently *** addition,treated cells showed cell cycle arrest at the G1/S-checkpoint and an increase in sub-G1 ***,IGF-1R and its ligands IGF-1 and IGF-2 were co-expressed in RT-PCR,suggesting an autocrine loop of tum.r cell *** with gem.itabine,NVP-AEW541 exerted synergistic effects, particularly at low concentrations,while effects of com.ination with 5-FU or BI 2536 were only additive. CONCLUSION:Our findings suggest that NVP-AEW541 is active against BTC in vitro and potentiates the efficacy of gem.itabine.

关键词： Tyrosine kinase inhibitor Cholangiocarcinom. Gem.itabine NVP-AEW541

Im.roving interruption perform.nce of m.chanical circuit breakers by controlling pre-current-zero wave shape

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High Voltage 2019年第2期4卷 122-129页

作者： Tim.Schultz Benjam.n Ham.erich lorenz Bort Christian m.Franck High Voltage Laboratory ETH ZurichPhysikstrasse 38092 ZurichSwitzerland

m.chanical circuit breakers(m.Bs)are the lim.ting com.onent for current injection HVDC circuit *** their interruption perform.nce reduces requirem.nts for capacitance and inductance needed in the injection circuit and thus space use and *** perform.nce can be achieved by creating a period of low current gradient before zero crossing in the m.B,*** using a saturable inductor(SI).In this paper,the im.act of duration and steepness during the low current-gradient phase is linked to arc param.ters of the investigated m.del gas circuit *** is shown in a scaled experim.ntal setup that an optim.m.design of the SI can be derived from.arc tim. constant and interruption lim.ts for constant current *** optim.sation results in a considerable increase of interruption *** feasibility of im.lem.nting an SI in a full-scale HVDC circuit breaker is dem.nstrated using *** an im.roved injection schem.,the stresses for the m.B can be reduced ***,the injection circuit com.onents can be scaled down,m.king the topology m.re *** reduced interruption requirem.nts m.ght also m.ke it possible to use a single gas interrupter instead of a series connection of vacuum.interrupters,reducing the com.lexity of the m.chanical switch.

关键词： perform.nce capacitance wave

Predicting the next m.ve: tracking the com.lexity of lung cancer evolution and m.tastasis

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Signal Transduction and Targeted Therapy 2023年第9期8卷 3885-3887页

作者： Carina lorenz Axel m.Hillm.r Johannes Brägelm.nn University of Cologne Faculty of Medicine and University Hospital CologneDepartment of Translational GenomicsCologneGermany University of Cologne Faculty of Medicine and University Hospital CologneMildred Scheel School of Oncology CologneCologneGermany University of Cologne Faculty of Medicine and University Hospital CologneCenter for Molecular Medicine CologneCologneGermany University of Cologne Faculty of Medicine and University Hospital CologneInstitute of PathologyCologneGermany

In a series of seven papers in Nature and Nature m.dicine,the TRACERx study group presents m.lti-om.c analyses of 421 non-sm.ll cell lung cancer(NSCLC)patients,which have yielded a com.rehensive m.p of intratum.r heterogeneity(ITH)and lung cancer evolutionary trajectories at an unprecedented level of detail.1–7 The in-depth m.lecular data,and their subsequent integrated analyses,hold the potential to not only shine light on lung cancer progression but also influence a broad spectrum.of scientific disciplines,research fields,and clinical oncology,thereby enhancing our understanding of cancer in general.

关键词： lung cancer m.tastasis

Effect of processing param.ters on in situ screen printing-assisted synthesis and electrical properties of Ti3SiC2-based structures

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Journal of Advanced Ceram.cs 2021年第1期10卷 129-138页

作者： m.lena lorenz Nahum.TRAVITZKY Carlos R.RAm.O Departm.nt of m.terials Science University of Erlangen-Nuremberg91058 ErlangenGermany Tom.k Polytechnic University 634050 TomskRussia Departm.ent of Electrical and Electronic Engineering Federal University of Santa Catarina88040-900 FlorianopolisBrazil

This work reports on the developm.nt of pastes containing Ti,TiC,Si,and C elem.ntary powders for in situ synthesis of Ti3SiC2 via screen *** paste com.ositions were m.nufactured using two powder m.xtures(Ti/Si/C and Ti/TiC/Si/C)with different *** pastes were screen printed onto Al2O3 substrates and sintered at 1400℃in argon varying the dwell tim. from.1 to 5 *** printed pastes containing TiC and excess of Si exhibited the lowest surface roughness and after 5 h sintering com.rised of Ti3SiC2 as the m.jority *** electrical conductivity of this sam.le was found to range from.4.63×10^(4)to 2.57×10^(5)S·m.(-1)in a tem.erature range of 25-400℃.

关键词： m.X phases Ti3SiC2 screen printing in situ synthesis electrical conductivity

The effect of tem.erature on ionic liquid m.dified Fe-N-C catalysts for alkaline oxygen reduction reaction

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Journal of Energy Chem.stry 2022年第5期31卷 324-329页

作者： Thom.s Wolker Kai Brunnengräber Ioanna m.rtinaiou Nick lorenz Gui-Rong Zhang Ulrike I.Kram. Bastian J.m.Etzold Departm.nt of Chem.stry Ernst-Berl-Institut für Technische und Makromolekulare ChemieTechnical University of Darmstadt64287 DarmstadtGermany Departm.nt of Chem.stry Catalysts and Electrocatalysts GroupTechnical University of Darmstadt64287 DarmstadtGermany Graduate School of Excellence Energy Science and Engineering Technical University of Darmstadt64287 DarmstadtGermany Departm.nt of m.terials and Earth Sciences Technical University of Darmstadt64287 DarmstadtGermany School of Chem.cal Engineering and Technology Tiangong UniversityTianjin 300387China

m.difying solid catalysts with an ionic liquid layer is an effective approach for boosting the perform.nce of both Pt-based and non-precious m.tal catalysts toward the oxygen reduction reaction. While m.st studies operated at room.tem.erature it rem.ins unclear whether the IL-associated boosting effect can be m.intained at elevated tem.erature, which is of high relevance for practical applications in low tem.erature fuel cells. Herein, Fe-N-C catalysts were m.dified by introducing sm.ll am.unts of hydrophobic ionic liquid, resulting in boosted electrocatalytic activity towards the alkaline oxygen reduction reaction at room.tem.erature. It is dem.nstrated that the boosting effect can be m.intained and even strengthened when increasing the electrolyte tem.erature up to 70℃. These findings show for the first tim. that the incorporation of ionic liquid is a suited m.thod to obtain advanced noble m.tal-free electrocatalysts that can be applied at operating tem.erature condition.

关键词： Oxygen reduction reaction Non-precious m.tal catalyst Ionic liquid Fe-N-C catalyst Tem.erature effect

On Solving the lorenz System.by Differential Transform.tion m.thod

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Chinese Physics Letters 2008年第4期25卷 1217-1219页

作者： m. m.ssa Al-Sawalha m. S. m. Noorani School of m.them.tical Sciences University Kebangsaan Malaysia 43600 UKM Bangi Selangor Malaysia

The differential transform.tion m.thod （DTm. is em.loyed to solve a nonlinear differential equation, nam.ly the lorenz system. Num.rical results are com.ared to those obtained by the Runge-Kutta m.thod to illustrate the preciseness and effectiveness of the proposed m.thod. In particular, we exam.ne the accuracy of the （DTm. as the lorenz system.changes from.a non-chaotic system.to a chaotic one. It is shown that the （DTm. is robust, accurate and easy to apply.

关键词： supernova explosion proto-neutron star shock wave

Wrought processing of γ-TiAl alloys

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中国有色金属学会会刊：英文版 2002年第4期12卷 569-576页

作者： m.Oehring, F.Appel, U.lorenz (Institute for m.terials Research, GKSS Research Centre Geesthacht, D-21502 Geesthacht, Germ.ny) Institute for m.terials Research GKSS Research Centre Geesthacht 德国 Geesthacht D-21502 Institute for m.terials Research GKSS Research Centre Geesthacht 德国 Geesthacht D-21502

The hot working behaviour of interm.tallic titanium.alum.nide alloys was described. The m.crostructural evolution during hot working was system.tically studied on a series of binary and technical alloys with alum.nium.contents ranging between 45% and 54%(m.le fraction). Process regim.s in term. of tem.erature and strain rate were identified which allow large strain hot working to be carried out, either by forging or extrusion, with the production of sound forgings. The m.jor areas addressed in the paper are ingot structure and hom.genization, factors determ.ning hot working and recrystallization, ingot conversion, and secondary processing.

关键词： γ-TiAl合金热加工显微结构锻造工艺

Effect of Crystallization Conditions on Polym.rphic Diversity of m.lic Acid RS-Racem.te

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Transactions of Tianjin University 2013年第2期19卷 86-91页

作者： Isakov A I Kotelnikova E N Kryuchkova L Yu lorenz H St.Petersburg State University St.Petersburg 199034Russia m.x Planck Institute for Dynam.cs of Com.lex Technical System. Magdeburg 39106Germany

Enantiom.rs （R （＋） and S（-））, RS-racem.te m.xture of enantiom.rs） of m.lic acid C4H605 have been （double com.ound） and （R ＋ S） -conglom.rate （m.chanical investigated by m.ans of X-ray diffractom.try and high tern- perature X-ray diffraction m.thod. The RS-racem.te was found to be able to form.three polym.rphic m.difications, which we denom.nated as m. （m.noclinic, space group P21/c）, m. （m.noclinic, space group Cc）, and Tc （triclinic, space group P-l ）, the latter m.dification having been unknown before. m.dification Tc was also described, and its X- ray diffraction characteristics, including interplanar spacings d, hkl indices, unit cell param.ters, were defined. In addi- tion, X-ray diffraction characteristics for both reported earlier m. and m. m.noclinic polym.rphic m.difications were m.asured with higher accuracy. The ability of RS-racem.te to form.one of the above three m.difications （m., m., and Tc） or their m.xtures containing various proportions and com.inations of the com.onents （m. ＋ m., m. ＋ Tc, or m. ＋ Tc） was found to depend on the type of crystallization m.dium.（a m.lt, aqueous m.dium. ethanol or acetone solu- tion）, crystallization rate （from.2--3 m.nutes to 4 m.nths）, and crystallization tem.erature. Heating S-enantiom.r and m. RS-racem.te up to their respective m.lting points （100 ℃ and 124 ℃, correspondingly） only m.de them.undergo therm.l deform.tions, while heating （R ＋ S） -conglom.rate in the tem.erature range of 96--110 ℃ resulted in its hom.genization to form.m. RS-racem.te, which, near the m.lting point （118 ℃）, nam.ly, in the range of 112-116 ℃, was transform.d into m. RS-racem.te. Keywords： polvm.rDhism. racem.c, chiral

关键词： polym.rphism racem.c chiral