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Impact of carbon-based nutrient enhancement on biofiltration performance for drinking water treatment

Journal of Environmental Sciences 2019年第8期31卷 124-131页

作者： Yu Zhao liz Taylor-Edmonds Robert C.Andrews Department of Civil and Mineral Engineering University of Toronto

Incorporation of a carbon-based nutrient enhancementstrategy for drinking water biofiltration is an attractive option, especially for source waters which contain recalcitrant organics. This study compared biofilters that were operated in parallel and individually enhanced with amino acids(including alanine, phenylalanine, and tryptophan), inulin, and sucrose to increase biomass concentration and promote biodegradation of dissolved organic carbon(DOC) in the source water, including disinfection by-product(DBP) precursors. Biomass activity was characterized by measuring adenosine tri-phosphate(ATP), dissolved oxygen(DO) consumption, and through the use of laccase and esterase enzyme assays. Performance was evaluated in terms of headloss,turbidity, p H, DOC, UV254, and DBP formation potential(DBP FP). The introduction of carbonbased nutrients significantly increased biomass activity, where ATP values peaked at 976 ng/g of filter media, 853 ng/g, and 513 ng/g for amino acids, inulin, and sucrose-spiked biofilters,respectively, while a non-spiked control only reached 104 ng/g. DO utilization by the enhanced biofilters was significantly higher than the control, with a strong correlation between ATP and DO uptake observed for all filters(R^2> 0.74). Laccase and esterase enzyme activities of enhanced biofilters were also elevated(p > 0.05), suggesting greater biodegradation potential. Operational parameters such as headloss development and turbidity control were not impaired by carbon supplementation strategies or an increase in biomass concentration and activity. However, the enhancement strategy did not provide improvement in terms of source water carbon removal(DOC and UV254) or DBP FP when treated filters were compared to a control.

关键词： Biological filtration Carbon enhancement Biomass Disinfection by-products Dissolved organic carbon

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Supramolecular organization of the sperm plasma membrane during maturation and capacitation

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Asian Journal of Andrology 2007年第4期9卷 438-444页

作者： Roy Jones Peter S. James liz Howes Andreas Bruckbauer David Klenerman The Babraham Institute Cambridge CB2 4AT UK Department of Chemistry University of Cambridge Cambridge CB2 1EW UK

Aim： In the present study, a variety of high resolution microscopy techniques were used to visualize the organization and motion of lipids and proteins in the sperm＇s plasma membrane. We have addressed questions such as the presence of diffusion barriers, confinement of molecules to specific surface domains, polarized diffusion and the role of cholesterol in regulating lipid rafts and signal transduction during capacitation. Methods： Atomic force microscopy identified a novel region （EqSS） within the equatorial segment of bovine, porcine and ovine spermatozoa that was enriched in constitutively phosphorylated proteins. The EqSS was assembled during epididymal maturation. Fluorescence imaging techniques were then used to follow molecular diffusion on the sperm head. Results： Single lipid molecules were freely exchangeable throughout the plasma membrane and showed no evidence for confinement within domains. Large lipid aggregates, however, did not cross over the boundary between the post-acrosome and equatorial segment suggesting the presence of a molecular filter between these two domains. Conclusion： A small reduction in membrane cholesterol enlarges or increases lipid rafts concomitant with phosphorylation of intracellular proteins. Excessive removal of cholesterol, however, disorganizes rafts with a cessation of phosphorylation. These techniques are forcing a revision of long-held views on how lipids and proteins in sperm membranes are assembled into larger complexes that mediate recognition and fusion with the egg. （Asian JAndrol 2007 July; 9： 438-444）

关键词： cholesterol lipid rafts single molecules sperm membranes

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手机对学生的负面影响看看这位老师为何如此担心她的学生

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空中英语教室（高级版．彭蒙惠英语） 2023年第2期 10-11,40,41页

作者： liz Shulman 不详

“我们知道‘抖音’对我们不好,但它比现实世界好。”这是我的一个九年级学生说的。他在今年春季学期的最后一天,在我的高一英语课上发表了这个想法。我们当时在课堂上讨论学生们的未来。有些学生提到在暑假学校会上保健课和驾驶课,其... 详细信息

“我们知道‘抖音’对我们不好,但它比现实世界好。”这是我的一个九年级学生说的。他在今年春季学期的最后一天,在我的高一英语课上发表了这个想法。我们当时在课堂上讨论学生们的未来。有些学生提到在暑假学校会上保健课和驾驶课,其他人提到在海滩和社区中心工作。那位学生指着一个看不见的地平线补充道:“但我很担心我们的未来。”

关键词：高一英语九年级学生保健课负面影响地平线课堂担心

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Learning from parental experience in a neonatal surgical unit:a qualitative service evaluation

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World Journal of Pediatric Surgery 2023年第3期6卷 147-153页

作者： Anna Littlejohns Emile Crouzen Rebecca Mernenko Fiona Metcalfe Waaka Moni-Nwinia Hemma Chauhan Bethan Johnson Douglas McConachie Elizabeth Lawson Victoria Tricklebank John G McElwaine Gurdeep S Sagoo liz McKechnie Gary Latchford Jonathan Sutcliffe Anaesthesia and Critical Care Leeds Teaching Hospitals NHS TrustLeedsUK Paediatric Surgery Leeds Children's HospitalLeedsUK Leeds Centre for Newborn Care Leeds Children's HospitalLeedsUK Faculty of Medicine and Health University of LeedsLeedsUK Academic Unit of Health Economics University of LeedsLeedsUK Institute of Health Sciences University of Leeds LeedsLeedsUK St James's University Hospital Department of Clinical and Health Psychology LeedsUK

Objectives Patient experience is directly related to health outcomes,and parental experience can be used as a proxy for this in neonatal *** project was designed to assess parental experience of neonatal surgical care to inform future service developments and improve the care we *** This was a qualitative study using rapid qualitative *** study was carried out in a large neonatal surgical intensive care unit in the *** of infants treated by the neonatal surgical team between March 2020 and February 2021,during the COVID-19 pandemic were *** sampling was used to ensure that a representative range of parents were interviewed.A semistructured interview was created and tested in a previous phase of *** questionnaire was used to ask parents open questions about different aspects of their infants’healthcare journey from the antenatal phase through to discharge from the neonatal unit(NUU).Results Rapid qualitative analysis was employed,and parental experiences were grouped into five main categories:before admission to the NNU,initial admission to NNU,information and support,COVID-19 and *** these five groups,we highlighted positive experiences to be fed back to the healthcare teams to reinforce good practice,areas that warranted improvement and suggestions for service *** The wealth of data generated from the interviews has been summarized and shared with healthcare teams who are putting the service improvement suggestions into *** tool is available for services that wish to measure parental experience.

关键词： qualitative service interview

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Plasticity of spermatogonial stem cells

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Asian Journal of Andrology 2015年第3期17卷 355-359页

作者： Paul S Cooke liz Simon Manjunatha K Nanjappa Theresa I Medrano Suzanne E Berry Department of Physiological Sciences College of Veterinary Medicine University of Florida Gainesville FL 32608 USA Department of Physiology Louisiana State University Health Sciences Center New Orleans LA 70112 USA Department of Comparative Biosciences College of Veterinary Medicine University of Illinois at Urbana-Champaign Urbana IL 61802 USA

There have been significant breakthroughs over the past decade in the development and use of pluripotent stem cells as a potential source of cells for applications in regenerative medicine. It is likely that this methodology will begin to play an important role in human clinical medicine in the years to come. This review describes the plasticity of one type of pluripotent cell, spermatogonial stem cells （SSCs）, and their potential therapeutic applications in regenerative medicine and male infertility. Normally, SSCs give rise to sperm when in the testis. However, both human and murine SSCs can give rise to cells with embryonic stem （ES） cell-like characteristics that can be directed to differentiate into tissues of all three embryonic germ layers when placed in an appropriate inductive microenvironment, which is in contrast to other postnatal stem cells. Previous studies have reported that SSCs expressed an intermediate pluripotent phenotype before differentiating into a specific cell type and that extended culture was necessary for this to occur. However, recent studies from our group using a tissue recombination model demonstrated that SSCs differentiated rapidly into another tissue, in this case, prostatic epithelium, without expression of pluripotent ES cell markers before differentiation. These results suggest that SSCs are capable of directly differentiating into other cell types without going through an intermediate ES cell-like stage. Because SSCs do not require reprogramming to achieve a pluripotent state, they are an attractive source of pluripotent cells for use in regenerative medicine.

关键词： pluripotency regenerative medicine spermatogenesis testis

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Brain Banks Spur New Frontiers in Neuropsychiatric Research and Strategies for Analysis and Validation

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Genomics, Proteomics & Bioinformatics 2019年第4期17卷 402-414页

作者： Le Wang Yan Xia Yu Chen Rujia Dai Wenying Qiu Qingtuan Meng liz Kuney Chao Chen Center for Medical Genetics&Hunan Key Laboratory of Medical Genetics School of Life SciencesCentral South UniversityChangsha 410078China Child Health Institute of New Jersey Department of NeuroscienceRutgers Robert Wood Johnson Medical SchoolNew BrunswickNJ 08901USA Psychiatry Department SUNY Upstate Medical UniversitySyracuseNY 13210USA Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100101China Affiliated Hospital of Guilin Medical University Guilin 541000China National Clinical Research Centre for Geriatric Disorders Xiangya HospitalCentral South UniversityChangsha 410000China

Neuropsychiatric disorders affect hundreds of millions of patients and families *** decode the molecular framework of these diseases,many studies use human postmortem brain *** studies reveal brain-specific genetic and epigenetic patterns via highthroughput sequencing *** best practices for the collection of postmortem brain samples,analyzing such large amounts of sequencing data,and interpreting these results are critical to advance *** provide an overview of human brain banks worldwide,including progress in China,highlighting some well-known projects using human postmortem brain samples to understand molecular regulation in both normal brains and those with neuropsychiatric ***,we discuss future research strategies,as well as state-of-the-art statistical and experimental methods that are drawn upon brain bank resources to improve our understanding of the agents of neuropsychiatric disorders.

关键词： Neuropsychiatric disorders Brain bank Postmortem brain Expression quantitative trait loci GWAS interpretation

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Laser-assisted dacryocystorhinostomy in nasolacrimal duct obstruction：5-year follow-up

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International Journal of Ophthalmology(English edition) 2018年第10期11卷 1616-1620页

作者： Mustafa Dogan Anar Alizada Güliz Fatma Yavas Orhan Kemal Kahveci Osman Bakan Department of Ophthalmology Faculty of Medicine AfyonKocatepe University Afyonkarahisar 03200 Turkey Department of Ophthalmology Faculty of MedicineHacettepe Univerisity Ankara 06100 Turkey Department of Otolarhinoaryngology Faculty of MedicineAfyon Kocatepe University Afyonkarahisar 03200 Turkey Medlife Hospital istanbul 34500 Turkey

AIM：To evaluate the long-term sucess rate of laserassisted dacryocystorhinostomy （L-DCR） in patients with nasolacrimal duct obstruction （NDO）.METHODS：Forty-one eyes of forty patients aged between 21-85y （mean 56.7y） who underwent L-DCR for the treatment of NDO were included in this retrospective,non-randomized study. The follow-up time was *** sucess was defined as the disappearance of epiphora under normal conditions and the presence of a patent ostium on lacrimal irrigation. Anatomical success was defined as a patent lacrimal passage on syringing besides continuing epiphora. Surgical failure was defined as persistent epiphora and closed ***：Twenty-seven of 40 patients （67.5%） were female and 13 of 40 patients （32.5%） were male. The NDO was right-sided in 17 （42.5%） patients and left-sided in 22（55%） patients whereas 1 （2.5%） patient had undergone bilateral surgery. In 11 （27.5%） patients there were additional nasal abnormalities requiring simultaneous surgical approach. The average time for L-DCR was 26.50±4.9min（16-39min） and the average total amount of laser energy used was 287±27.9 J （239-367 J）. At the 5y follow-up, anatomical sucess rate was 75.0%（30 patients） and functional success rate was 65.0%（26 patients）, whereas surgical failure was seen in 25%（10 patients）. Revision of surgery was performed in 10 cases （25.0%）; failure of revision surgery was seen in 2 cases（5.0%）.CONCLUSION： Transcanalicular L-DCR is a reliable and fast procedure in the treatment of NDO. It can be alternative to external DCR which is accepted as the gold standard currently. The functional and anatomical success rate is higher in the first months and years, but still satisfactory at fifth year.

关键词： nasolacrimal duct obstruction laser-assisted dacryocystorhinostomy 5-year follow-up

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学习指导

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丛书名：外研社丽声拼读故事会

2011年

作者： (英)Clare Kirtley (英)liz Miles

本书为：塔拉的派对、兽医葆拉、伯特，你去哪儿了？克莱尔和游乐园、小鹿和蠼螋、杰史和巨人的学习大纲，包括介绍拼读规则、拼读指导和拓展训练。

ISBN: (纸本)9787513509206;9787894788122

关键词：英语

来源：畅想之星图书光盘版（南... 评论

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Binding of Cry δ-endotoxins to brush border membrane vesicles of Helicoverpa armigera and Helicoverpa punctigera （Lepidoptera： Noctuidae）

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Insect Science 2005年第4期12卷 231-240页

作者： CHUNYAN LIAO liz BROOKS STEPHEN C. TROWELL RAYMOND J. AKHURST CSIRO Entomology Australian National University ACT Australia Division of Biochemistry and Molecular Biology Australian National University ACT Australia

到 Cry1Ac 的 Helicoverpa 有佩带徽章权利的人 a 的相对低的危险性，它到在在转基因的棉花的 Cry1Ac 的表示的化学杀虫药剂和季节的衰落的抵抗的历史要求了表示二杀虫的蛋白质提供这个多民族的害虫的持续控制的棉花的开发。管理抵抗问... 详细信息

到 Cry1Ac 的 Helicoverpa 有佩带徽章权利的人 a 的相对低的危险性，它到在在转基因的棉花的 Cry1Ac 的表示的化学杀虫药剂和季节的衰落的抵抗的历史要求了表示二杀虫的蛋白质提供这个多民族的害虫的持续控制的棉花的开发。管理抵抗问题，第二杀虫的蛋白质有行动 toCry1Ac 的一个显著地不同的模式，是必要的。到在象 H 一样的几种的 Cry1A 蛋白质的抵抗的一个普通特征。有佩带徽章权利的人啊哈是在有约束力的地点的一个变化。为在刷子的一些叫喊蛋白质的有约束力的地点的研究毗邻 H 的膜泡(BBMV ) 。有佩带徽章权利的人 and Helicoverpa punctigera 被承担。为 Cry1Ac 的 Thebinding 亲密关系比为 Cry1Ab 高，匹配他们毒性， andCry1Ac 和 Cry1Ab 被发现分享在两 H 的至少一个有约束力的地点的亲戚。有佩带徽章权利的人 and ***。然而， Cry2Aa 没为绑定与 Cry1Ac 竞争能那么与 Cry1Ac 在联合在转基因的棉花被使用控制 H。有佩带徽章权利的人一 and 管理抵抗。Variationin 三不同 H 的危险性。有佩带徽章权利的人一到 Cry1Ac 的紧张与参数 B_( 最大)/K_(com ) 相关。

关键词： δ-内毒素囊膜鳞翅类昆虫学 Helicoverpa punctigera 棉铃虫

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海王星最新的热力图显示出令人惊讶的温度起伏

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中国科技教育 2022年第6期 67-69页

作者： liz Kruesi 王麒(编译) 不详

海王星的大气温度就像坐上出人意料的翻滚过山车,对于科学家来说,恐怕要花数十年才能将发生在遥远行星上的事件拼合到一起。这颗冰巨星的全球温度在2003-2012年间的夏季伊始便下降8℃,之后从2018-2020年,热力图显示出这颗行星的南极戏... 详细信息

海王星的大气温度就像坐上出人意料的翻滚过山车,对于科学家来说,恐怕要花数十年才能将发生在遥远行星上的事件拼合到一起。这颗冰巨星的全球温度在2003-2012年间的夏季伊始便下降8℃,之后从2018-2020年,热力图显示出这颗行星的南极戏剧性地亮了起来,这意味着那个地方存在11℃的增温。研究人员就此在4月11日出版的《行星科学杂志》作了报告。

关键词：行星科学大气温度全球温度过山车热力图南极海王星温度起伏

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