检索结果-南通市图书馆

Photodegradation of α-naphthaleneacetic acid in aqueous solution

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2001年第3期13卷 361-364页

作者： liu hui jun, zhou Zhu fei, liu Wei ping (Environmental Science Institute, Zhejiang University, Hangzhou 310027, China. 浙江大学浙江杭州 310027

Kinetic processes of a-naphthaleneacetic acid (NAA) photolysis were studied under different conditions. The results showed that the ultraviolet light was more effective than fluorescent light in promoting degradation, and the degradation of NAA under ultraviolet light followed the first order kinetics with the photolysis rate constant of 1.15 x 10-2 min-1 and half-life time (t1/2) of 60 min. Further, it was proved that the photolysis rate was higher in the presence of oxygen, titanium dioxide (TiO2), and low pH (acidic solution). At last, two photolysis intermediates were identified by GC-MS and possible photolysis pathways were proposed.

关键词： Acids Degradation Fluorescence Photolysis Solutions

Determination of risperidone in human plasma by HPLC-MS/MS and its application to a pharmacokinetic study in Chinese volunteers

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2008年第2期9卷 114-120页

作者： Ming-zhu HUANG Jian-zhong SHENTU Jun-chun CHEN Jian liu hui-li zhou Research Center of Clinical Pharmaceutical Science the First Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310003 China

This study presents a rapid, specific and sensitive liquid chromatography/tandem mass spectrometry (LC-MS/MS) assay for determination of risperidone (RIS) in human serum using paroxetine as an internal standard (IS). An Alltima-C18 column (2.1 mm×100 mm, 3 μm) and a mobile phase consisting of 0.1% formic acid-acetonitrile (40:60, v/v) were used for separation. The analysis was performed by selected reaction monitoring (SRM) method, and the peak area of the m/z 411.3→191.1 transition for RIS was measured versus that of the m/z 330.1→192.1 transition for IS to generate the standard curves. The assay linearity of RIS was confirmed over the range 0.25～50.00 ng/ml and the limit of quantitation was 0.05 ng/ml. The linear range corresponds well with the serum concentrations of the analytes obtained in clinical pharmacokinetic studies. Intraday and interday relative standard deviations were 1.85%～9.09% and 1.56%～4.38%, respectively. The recovery of RIS from serum was in the range of 70.20%～84.50%. The method was successfully applied to investigate the bioequivalence between two kinds of tablets (test versus reference products) in 18 healthy male Chinese volunteers. The result suggests that two formulations are bioequivalent.

关键词： Risperidone High performance liquid chromatography-mass spectrometry (HPLC-MS) Pharmacokinetics

Rational modulation of fluorophosphate cathode by anionic groups to reduce the polarization behavior for fast-charging sodium-ion batteries

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 509-521页

作者： Xinyuan Wang Fan Zhang Xingyu zhou Qian Wang Changyu liu Yangyang liu hui Wang Xiaojie liu Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education College of Chemistry & Materials Science Northwest University

Na3V2（PO4）2O2F （VP） is recognized as a promising cathode material for sodium-ion batteries due to its stable structural framework and high specific *** functional theory （DFT） and finite element simulations show that incorporating SO42-into VP decreases its band gap,lowers the migration energy barrier,and ensures a uniform Na+concentration gradient and stress distribution during charge and discharge ***,the average Na+diffusion coefficient of Na3V2（PO4）1.95（SO4）0.05O2F（VPS-1） is roughly double that of VP,leading to enhanced rate capability (80 C,75.5 mAh g-1) and cycling stability (111.0 mAh g-1capacity after 1000 cycles at 10 C current density) for ***-1 exhibits outstanding fast-charging capabilities,achieving an 80%state of charge in just 8.1 *** assembled VPS-1//SbSn/NPC full cell demonstrated stable cycling over 200 cycles at a high 5 C current,maintaining an average coulombic efficiency of 95.35%.

关键词： Anionic group modulation Polarization behavior Fast-charging Sodium-ion battery Fluorophosphate Cathode

Protective effect of tea polyphenols against paracetamol-induced hepatotoxicity in mice is significanly correlated with cytochrome P450 suppression

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2009年第15期15卷 1829-1835页

作者： Xia Chen Chang-Kai Sun Guo-Zhu Han Jin-Yong Peng Ying Li Yan-Xia liu Yuan-Yuan Lv Ke-Xin liu Qin zhou hui-Jun Sun Department of Pharmacology Daiian Medical University Dalian 116044 Liaoning Province China

AIM： To investigate the hepatoprotective activity of tea polyphenols （TP） and its relation with cytochrome P450 （CYP450） expression in mice. METHODS： Hepatic CYP450 and CYPbs levels were measured by UV-spectrophotometry in mice 2 d after intraperitoneal TP （25, 50 and 100 mg/kg per day）. Then the mice were intragastricly pre-treated with TP （100, 200 and 400 mg/kg per day） for six days before paracetamol （1000 mg/kg） was given. Their acute mortality was compared with that of control mice. The mice were pre-treated with TP （100, 200, and 400 mg/kg per day） for five days before paracetamol （500 mg/kg） was given. Hepatic CYP2E1 and CYPIA2 protein and mRNA expression levels were evaluated by Western blotting, immunohistochemical staining and transcriptase-polymerase chain reaction. RESULTS： The hepatic CYP450 and CYPb5 levels in mice of TP-treated groups （100, 200 and 400 mg/kg per day） were decreased in a dose-dependent manner compared with those in the negative control *** significantly attenuated the paracetamol-induced hepatic injury and dramatically reduced the mortality of paracetamol-treated mice. Furthermore, TP reduced CYP2E1 and CYPIA2 expression at both protein and mRNA levels in a dose-dependent manner. CONCLUSION： TP possess potential hepatoprotective properties and can suppress CYP450 expression.

关键词： Tea polyphenols Cytochrome P450 Paracetamol-induced hepatotoxicity

Aspirin combined with mechanical measures to prevent venous thromboembolism after total knee arthroplasty： a randomized controlled trial

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2014年第12期127卷 2201-2205页

作者： Jiang Yi Du hui liu Jian zhou Yixin Department of Joint Reconstructive Surgery Beijing Jishuitan HospitalBeijing 100035China

Background Venous thromboembolism （VTE） is an important complication after major orthopedic *** methods represent the main strategy of VTE *** use of aspirin in VTE prevention is still controversial worldwide,especially in *** purpose of this study was to evaluate the role of aspirin combined with mechanical measures in the prevention of VTE after total knee arthroplasty （TKA）.Methods Between January 2012 and May 2013 and in accordance with the inclusion criteria,120 patients undergoing TKA were randomly allocated to two *** prevent VTE,patients in group A received aspirin combined with mechanical measures postoperatively,while patients in group B received low-molecular-weight heparin （LMWH） sodium and rivaroxaban sequentially in combination with mechanical measures *** surgeries were performed by one surgeon using a posterior-stabilized cemented *** two groups were followed up and compared for the incidence of deep vein thrombosis （DVT） by duplex ultrasound scan and clinical VTE *** adverse events,the blood loss index,and the cost of VTE prevention were also *** DVT was detected in 10 of 60 patients in group A （16.7％,95％ CI：7.3％-26.1％） compared with 11 of 60 in group B （18.3％,95％ CI：8.5％-27.8％）（P=0.500）.There is no statistical evidence supporting the inferior effect of aspirin in preventing DVT as compared with the other *** were no cases of symptomatic VTE or death during the follow-up *** of ecchymosis was lower in group A than in group B,and the differences were statistically *** in group A had the lower blood loss index as compared with patients in group *** transfusion cases were found in both *** differences were statistically *** cost of VTE prevention analysis indicated a cost reduction using aspirin in group A compared with using LMWH and rivaroxaban in group *** Aspirin combined with mechanical measu

关键词： aspirin venous thromboembolism prevention arthroplasty replacement knee

The Influence of Transgenic cry1Ab/cry1Ac,cry1C and cry2A Rice on Non-Target Planthoppers and Their Main Predators Under Field Conditions

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Agricultural Sciences in China 2011年第11期10卷 1739-1747页

作者： HANYu XU Xue-liang MA Wei-hua YUAN Ben-qi WANG hui liu Fang-zhou WANG Man-qun WU Gang HUA Hong-xia Hubei lnsect Resources Utilization and Sustainable Pest Management Key Laboratory College of Plant Science and Technology HuazhongAgricultural University Wuhan 430070 P.R.China

Transgenic Bt rice has been shown to be an effective means of controlling Lepidoptera pests of rice. However, the potential roles of transgenic rice on planthoppers and their predators need to be investigated before its commercialization. Population density, species dominance and population dynamics are important parameters of arthropods populations in field. So the impacts of three transgenic Bt rice strains expressing crylAb/crylAc, crylC and cry2A on population density, species dominance and population dynamics of three species of planthoppers （Nilaparvata lugens, Sogatella furcifera and Laodelphax striatellus） and their three main predators （ Cyrtorhinus lividipennis, Pirata subpiraticus and Theridium octomaculatum） were evaluated at three sites in Hubei Province, China, in the current study. The results showed that among three species of planthoppers, both in transgenic and non-transgenic rice field, the predominant species ofplanthoppers within phytophagous guild was S. furcifera at any site either growing season （46-50%）. Significantly higher population density ofN. lugens was observed in T2A-1 field relative to Minghui 63 field at Wuxue in 2010. The species dominance of predator, P. subpiraticus, in TT51 field was significantly higher than that in T 1 C-19 and T2A-1 fields in 2009 at Xiaogan site. Sampling date significantly influenced six arthropods except for P. subpiraticus in 2010. The interaction between rice strain^sampling date had no significant adverse effects on the population dynamics of three species of planthoppers and their predators, except for several individual species in 2009. The interaction among rice strain^sampling date^sampling site also had no significant effect on six arthropods except for S. furcifera in 2009. The results indicated that transgenic Bt rice expressing crylAb/crylAc, cry2A and crylC had no significant adverse effects on the population dynamics of three planthoppers and their predators in most investigated data and samp

关键词： planthopper predator transgenic Bt rice population dynamics species dominance population density

Dysfunction of peripheral blood dendritic cells from patients with chronic hepatitis B virus infection

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2001年第4期7卷 537-541页

作者： Fu-Sheng Wang Li-He Xing Ming-Xu liu Chuan-Lin Zhu hui-Gang liu hui-Fen Wang zhou-Yun Lei Division of Biological Engineering,~2 Fourth Department of Liver Diseases,Beijing Institute of Infectious Diseases,Beijing Hospital of Infectious Diseases,Beijing 100039,China Division of Biological Engineering Beijing Institute of Infectious Diseases 26 Fengtai Road Beijing 100039 China. fswang@***

AIM: To identify the property of dendritic cells (DCs) of peripheral blood monocytes (PBMC) in patients with chronic HBV infection. METHODS: Twenty patients with persistent HBV infection were included in this study, 10 healthy subjects being used as a control group. The peripheral blood mononuclear cells (PBMC) of T cell-depleted populations were incubated and induced into mature dendritic cells in the RPMI-1640 medium in the presence of cytokines GM-CSF, IL-4, FLt-3,TNF-alpha and 100mL.L(-1 )of fetal calf serum for a total of 10-12 days. The expressions of surface markers on DCs were evaluated using flow cytometric analysis. ELISA method was used to determine the cytokine levels of interleukin-12 (IL-12) and IL-10 in the supernatant produced by DCs. For detection of the stimulatory capacity of DCs to T cell proliferation, mytomycin C-treated DC were incubated with allogenic T cells. RESULTS: A typical morphology of mature DCs from healthy subjects and HBV-infected patients was induced in in vitro incubation, but the proliferation ability and cellular number of DCs from HBV-infected patients significantly decreased compared with healthy individuals. In particular, the expression levels of HLA-DR, CD80 (B7-1) and CD86 (B7-2) on DC surface from patients were also lower than that from healthy individuals (0.46 vs 0.92 for HLA-DR, 0.44 vs 0.88 for CD80 and 0.44 vs 0.84 for CD86,P<0.05). The stimulatory capacity and production of IL-12 of DCs from patients in allogenic mixed lymphocyte reaction (AMLR) significantly decreased, but the production level of nitric oxide (NO) by DCs simultaneously increased compared with healthy subjects (86 +/- 15 vs 170 +/- 22 micromol.L(-1), P <0.05). CONCLUSION: The patients with chronic HBV infection have the defective function and immature phenotype of dendritic cells, which may be associated with the inability of efficient presentation of HBV antigens to host immune system for the clearance of HBV.

关键词： Adolescent Adult Antigens, Surface Cell Division Child Dendritic Cells Female Flow Cytometry Hepatitis B, Chronic Humans Interleukin-10 Interleukin-12 Male Middle Aged Nitric Oxide Research Support, Non-U.S. Gov't

P300 EEG Recognition Based on SVM Approach

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Biomedical Engineering(English Edition) 2009年第1期18卷 35-39页

作者： liu hui zhou Wei-dong HUANG An-hu College of Information Science and Engineering Shandong University Jinan 250100 China

In this paper, we used SVM method to detect P300 signal. Before training a classification parameter for the SVM, several preprocessing operations were applied to the data including filtering, downsampling, single trial extraction, windsorizing, electrode selection et al. With the SVM algorithm, the classification accuracy could be up to above 80%. In some cases, the accuracy could reach 100%. It is suitable to use SVM for P300 EEG recognition in the P300-based brain-computer interface (BCI) system. Our further work will include the improvement to yield higher classification accuracy using fewer trials.

关键词： support vector machine ( SVM ) event related potential (ERP) P300 EEG classification brain-computer interface (BCI)

A NOVEL NULLING ALGORITHM IN THE SUBARRAY OF A LARGE ARRAY

在线全文

学校读者我要写书评

暂无评论

Journal of Electronics(China) 2006年第5期23卷 795-797页

作者： liu hui zhou Yinqing Xu Huaping Lab 201 Beijing University of Aeronautics ＆ Astronautics Beijing 100083 China

Forming nulls in the radiation pattern of an antenna is to suppress the interference from certain directions or to cancel desired signals. This letter presents an effective method based on the Gram-Schmidt orthogonal algorithm for fonning nulls in the subarray of a large array. The theory and realizing methods are discussed, and the corresponding fonnulas are derived in details. The simulation results are given to demonstrate the feasibility, the availability and the quick-convergence of the presented method.

关键词： Gram-Schmidt orthogonal algorithm Antenna pattern Subarray