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Chinese Physics Letters 2018年第8期35卷 58-61页

作者： Tian-You Gao Dong-Fang Zhang ling-ran kong Rui-Zong Li Kai-Jun Jiang State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Wuhan Institute of Physics and MathematicsChinese Academy of SciencesWuhan 430071 Center for Cold Atom Physics Chinese Academy of SciencesWuhan 430071 University of Chinese Academy of Sciences Beijing 100049

We experimentally observe the dynamic evolution of atoms in the evaporative cooling, by in-situ imaging the plugged hole of ultracold atoms. Ultracold rubidium atoms confined in a magnetic trap are plugged using a blue-detuned laser beam with a waist of 20 m at a wavelength of 767 nm. We probe the variation of the atomic temperature and width versus the radio frequency in the evaporative cooling. Both the behaviors are in good agreement with the calculation of the trapping potential dressed by the rf signal above the threshold temperature,while deviating from the calculation near the phase transition. To accurately obtain the atomic width, we use the plugged hole as the reference to optimize the optical imaging system by precisely minimizing the artificial structures due to the defocus effect.

关键词： Observation of Atomic Dynamic Behaviors in the Evaporative Cooling by In-Situ Imaging the Plugged Hole of Ultracold Atoms

Expansion dynamics of a spherical Bose–Einstein condensate

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Chinese Physics B 2019年第10期28卷 478-482页

作者： Rui-Zong Li Tian-You Gao Dong-Fang Zhang Shi-Guo Peng ling-ran kong Xing Shen Kai-Jun Jiang State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Wuhan Institute of Physics and MathematicsChinese Academy of SciencesWuhan 430071China Center for Cold Atom Physics Chinese Academy of SciencesWuhan 430071China School of Physics University of Chinese Academy of SciencesBeijing 100049China

We experimentally and theoretically observe the expansion behaviors of a spherical Bose-Einstein condensate. A rubidium condensate is produced in an isotropic optical dipole trap with an asphericity of 0.037. We measure the variation of the condensate size in the expansion process after switching off the trap. The free expansion of the condensate is isotropic,which is different from that of the condensate usually produced in the anisotropic trap. We derive an analytic solution of the expansion behavior based on the spherical symmetry, allowing a quantitative comparison with the experimental measurement. The interaction energy of the condensate is gradually converted into the kinetic energy during the expansion and after a long time the kinetic energy saturates at a constant value. We obtain the interaction energy of the condensate in the trap by probing the long-time expansion velocity, which agrees with the theoretical calculation. This work paves a way to explore novel quantum states of ultracold gases with the spherical symmetry.

关键词： Bose-Einstein condensate spherical trap free expansion

METTL5 promotes cell proliferation,invasion,and migration by up-regulating Toll-like receptor 8 expression in colorectal cancer

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 2006-2017页

作者： ling-Shang kong ran Tao Yi-Fan Li Wen-Bin Wang Xue Zhao Department of General Surgery The Second Affiliated Hospital of Anhui Medical UniversityHefei 230001Anhui ProvinceChina Department of Vascular Surgery The Second Affiliated Hospital of Anhui Medical UniversityHefei 230002Anhui ProvinceChina Department of General Surgery The First Affiliated Hospital of Anhui Medical UniversityHefei 230001Anhui ProvinceChina Anhui Public Health Clinical Center Hefei 230012Anhui ProvinceChina Department of Scientific Research Anhui Public Health Clinical CenterHefei 230012Anhui ProvinceChina Department of Scientific Research The First Affiliated Hospital of Anhui Medical UniversityHefei 230001Anhui ProvinceChina

BACKGROUND N6-methyladenosine(m6A)modification represents the predominant alteration found in eukaryotic messenger RNA and plays a crucial role in the progression of various ***,despite its significance,the comprehensive investigation of METTL5,a key m6A methyltransferase,in colorectal cancer(CRC)remains *** To investigate the role of METTL5 in *** We assessed METTL5 expression levels in clinical samples obtained from CRC patients as well as in CRC cell *** elucidate the downstream targets of METTL5,we performed RNA-sequencing analysis coupled with correlation analysis,leading us to identify Toll-like receptor 8(TLR8)as a potential downstream *** vitro functional assessments of METTL5 and TLR8 were conducted using CCK-8 assays,scratch assays,as well as assays measuring cell migration and *** Our findings reveal a pronounced upregulation of METTL5 expression in both CRC cells and tissues,which correlated significantly with an unfavorable *** vitro experiments unequivocally demonstrated the oncogenic role of METTL5,as evidenced by its promotion of CRC cell proliferation,invasion,and ***,we identified TLR8 as a downstream target of METTL5,and subsequent down-regulation of TLR8 led to a significant inhibition of CRC cell proliferation,invasion,and tumor *** The heightened expression of METTL5 in CRC is strongly associated with clinicopathological features and a poor prognosis,thereby underscoring its potential utility as a critical marker for facilitating early diagnosis and prognostication in CRC.

关键词： METTL5 Toll-like receptor 8 Colorectal cancer

Electroencephalogram findings in 10 patients with post-stroke epilepsy:A retrospective study

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World Journal of Clinical Cases 2024年第2期12卷 249-255页

作者： Li-Min Wen ran Li Yan-ling Wang Qing-Xia kong Min Xia Clinical Medicine College Jining Medical UniversityJining 272067Shandong ProvinceChina School of Basic Medical Sciences Shandong UniversityJinan 250012Shandong ProvinceChina Department of Neurology The Affiliated Hospital of Jining Medical UniversityJining 272007Shandong ProvinceChina

BACKGROUND Post-stroke epilepsy is a common and easily overlooked complication of acute cerebrovascular ***-term seizures can seriously affect the prognosis and quality of life of ***(EEG)is the simplest way to diagnose epilepsy,and plays an important role in predicting seizures and guiding *** To explore the EEG characteristics of patients with post-stroke epilepsy and improve the detection rate of inter-seizure epileptiform *** From January 2017 to June 2020,10 patients with post-stroke epilepsy in our hospital were *** clinical,imaging,and EEG characteristics were *** stroke location,seizure type,and ictal and interictal EEG manifestations of the patients with post-stroke epilepsy were then retrospectively *** In all 10 patients,epileptiform waves occurred in the side opposite to the stroke lesion during the interictal stage;these manifested as sharp wave,sharp-wave complex,or spike discharges in the anterior head lead of the side opposite to the *** In EEG,epileptiform waves can occur in the side opposite to the stroke lesion in patients with post-stroke epilepsy.

关键词： Post-stroke epilepsy Electroencephalogram Seizure Stroke Slow wave

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Light(Science & Applications) 2024年第2期13卷 333-346页

作者： Yifan Sun Qian Li ling-Jun kong Xiangdong Zhang Key Laboratory of advanced optoelectronic quantum architecture and measurements of Ministry of Education Beijing Key Laboratory of Nanophotonics&Ultrafine Optoelectronic SystemsSchool of PhysicsBeijing Institute of Technology100081BeijingChina

Compared with electrical neural networks,optical neural networks(ONNs)have the potentials to break the limit of the bandwidth and reduce the consumption of energy,and therefore draw much attention in recent *** far,several types of ONNs have been ***,the current ONNs cannot realize the acceleration as powerful as that indicated by the models like quantum neural *** to construct and realize an ONN with the quantum speedup is a huge ***,we propose theoretically and demonstrate experimentally a new type of optical convolutional neural network by introducing the optical *** is called the correlated optical convolutional neural network(COCNN).We show that the COCNN can exhibit“quantum speedup”in the training *** character is verified from the two *** is the direct illustration of the faster convergence by comparing the loss function curves of the COCNN with that of the traditional convolutional neural network(CNN).Such a result is compatible with the training performance of the recently proposed quantum convolutional neural network(QCNN).The other is the demonstration of the COCNN’s capability to perform the QCNN phase recognition circuit,validating the connection between the COCNN and the ***,we take the COCNN analog to the 3-qubit QCNN phase recognition circuit as an example and perform an experiment to show the soundness and the feasibility of *** results perfectly match the theoretical *** proposal opens up a new avenue for realizing the ONNs with the quantum speedup,which will benefit the information processing in the era of big data.

关键词： process quantum convolution

Electrolyte effect on electrochemical behaviors of manganese fluoride material for aqueous asymmetric and symmetric supercapacitors

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Rare Metals 2024年第3期43卷 1048-1061页

作者： Zheng-Hua He Jian-Fei Gao ling-Bin kong State Key Laboratory of Advanced Processing and Recycling of Non-Ferrous Metals Lanzhou University of TechnologyLanzhou730050China School of Materials Science and Engineering Lanzhou University of TechnologyLanzhou730050China

Exploring wide voltage window materials is not only an available measure to enhance the energy density of hybrid supercapacitor(HSCs),but also avoids the dynamic mismatch caused by different energy storage mechanisms of two electrodes in assembled symmetrical ***,there are few reports about the wide potential window materials except Bi_(2)O_(3)and VO_(2).Therefore,the MnF_(2)synthesized by solvothermal reaction was served as the electrode for *** MnF_(2)exhibited electrochemical activity in alkaline solution in three-electrode system,especially with a wide potential window from-0.8 to+0.5 V in 2 mol·L^(-1)***,the assembled MnF_(2)//MnF_(2)symmetrical HSC had a potential window of 1.5 V,and it exhibited outstanding long-cycle ***,when MnF_(2)was taken as the negative and positive respectively,the potential windows of asymmetric devices CoMoO_(4)//MnF_(2)and MnF_(2)//Activated Carbon(AC)could reach 1.3 and 1.45 V,respectively,showing excellent cycle *** work shows that MnF_(2)material has great research value in HSC,and provides a new research direction for developing high-performance devices.

关键词： Manganese fluoride Potential window Hybrid supercapacitors Electrochemical performance

Vitamin D binding protein in psychiatric and neurological disorders:Implications for diagnosis and treatment

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Genes & Diseases 2024年第5期11卷 324-334页

作者： ling Li Bing Han Yan kong Gaojia Zhang Zhijun Zhang Research Institution of Neuropsychiatry School of MedicineSoutheast UniversityNanjingJiangsu 210009China Department of Neurology Affiliated Zhongda HospitalNanjingJiangsu 210009China Department of Pharmacology Jiangsu Provincial Key Laboratory of Critical Care MedicineSchool of MedicineSoutheast UniversityNanjingJiangsu 210009China Department of Biochemistry and Molecular Biology School of MedicineSoutheast UniversityNanjingJiangsu 210009China Brain Cognition and Brain Disease Institute Department of Mental Health and Public HealthFaculty of Life and Health SciencesShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong 518055China

Vitamin D binding protein(VDBP)serves as a key transporter protein responsible for binding and delivering vitamin D and its metabolites to target *** plays a crucial part in the inflammatory reaction following tissue damage and is engaged in actin *** research has shed light on its potential role in various diseases,leading to a growing interest in understanding the implications of VDBP in psychiatric and neurological *** purpose of this review was to provide a summary of the existing understanding regarding the involvement of VDBP in neurological and psychiatric *** examining the intricate interplay between VDBP and these disorders,this review contributes to a deeper understanding of underlying mechanisms and potential therapeutic *** gained from the study of VDBP could pave the way for novel strategies in the diagnosis,prognosis,and treatment of psychiatric and neurological disorders.

关键词： Neurological disorder Polymorphism Psychiatric disorder Structure Vitamin D binding protein

Lead-free(Ba,Sr)TiO_(3)-based ceramics with superior tunable properties by the semi-solution method

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Journal of Advanced Ceramics 2024年第6期13卷 746-756页

作者： Yi Zhao Wenfeng Liu Dongsheng ran Yihang Jin Zhiyuan Li Chengzhi Zhong Fanyi kong Shengtao Li State Key Laboratory of Electrical Insulation and Power Equipment Xi’an Jiaotong UniversityXi’an 710049China Jiaxing Electric Power Company State Grid Zhejiang Electric Power Co. Ltd.Jiaxing 314000China

High-performance dielectric tunable materials with both high dielectric tunability and low dielectric loss are urgently needed for new-generation electronic tunable *** the present study,a new system,(Ba_(0.675)Sr_(0.325))_(1−x)La_(x)Ti_(1−x)MnxO_(3)(x=0.25%,0.5%,0.75%,and 1.0%),was *** acceptor dopant Mn was added to lower dielectric loss,while the donor dopant La was introduced to enhance dielectric *** samples were prepared using the conventional solid-state(CS)reaction method and the semi-solution(SS)*** experimental results showed that the morphology of the ceramics was optimized by further improving the processing *** microstructures,homogeneous grains,and uniform dopant distributions could be achieved successfully by the semi-solution ***,a significant enhancement in the tunable properties was realized owing to the improved microstructure mentioned *** optimum tunable properties occurred in the samples prepared by the semi-solution method at x=0.75%,with a high dielectric tunability of 85.0%,a low dielectric loss of 0.0011,and an excellent figure of merit(FOM)of *** tunable properties of(Ba,Sr)TiO_(3)(BST)ceramics were even superior to those of lead-based materials,with an FOM of approximately *** the results suggested that the semi-solution method rendered BST ceramics more promising for applications in tunable devices.

关键词： microstructure tunable properties (Ba,Sr)TiO_(3)(BST)ceramics semi-solution(SS)method

Reaction behavior of MgO refractory with high-Mn and high-Al steel

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Journal of Iron and Steel Research International 2024年第6期31卷 1389-1398页

作者： ling-zhong kong Lin Zu Jie Yang Xi-min Zang Xin Yang Ming Kang School of Materials and Metallurgy University of Science and Technology LiaoningAnshan 114051LiaoningChina

To understand the mechanism of the interfacial reaction between high-Mn and high-Al steel and MgO refractory,a series of laboratory experiments as well as thermodynamic calculations were *** effects of Mn and Al contents in the steel and the reaction time on the interfacial reaction were *** was observed that the erosion of the MgO refractory is caused by the reaction of Al and Mn in the steel with MgO in the refractory,which would lead to the formation of(Mn,Mg)O·Al_(2)O_(3) spinel and(Mn,Mg)O solid *** formation mechanism of the spinel and solid solution is as *** Al in the steel firstly reacts with MgO in the refractory to generate MgO·Al_(2)O_(3) spinel,and then,the spinel reacts with Mn in the steel to form(Mn,Mg)O·Al_(2)O_(3) ***,the MnO in the spinel reacts with the MgO in the inner refractory to form(Mn,Mg)O solid *** addition,only(Mn,Mg)O·Al_(2)O_(3) spinel is present in the interfacial reaction layer of the refractory when the Al content in the steel is sufficient.

关键词： High-Mn high-Al steel MgO refractory Reaction behavior Spinel

Microstructure and room temperature fracture toughness of Nb-Si-based alloys with Sr addition

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Rare Metals 2024年第8期43卷 3904-3912页

作者： Yong-Lin Huang Li-Na Jia Bin kong Yue-ling Guo Na Wang School of Materials Science and Engineering Beihang UniversityBeijing 100191China

Nb-Si-based alloys show great potential to surpass the widely used Ni-based *** element Sr is widely applied in aluminum and magnesium alloys,but reports about the effects of Sr on Nb-Si-based alloys are quite ***,Nb-Si-based alloys with nominal compositions of Nb-15Si-24Ti-4Cr-2Al-2Hf-0/0.05/0.15Sr(at%)were prepared by directional solidification and heat *** microstructural characterization and room temperature fracture toughness of Nb-Si-based alloy were systematically *** show that all these alloys consist of Nb_5Si_3 phase embedded within Nb solid solution(Nb_(ss)) *** Nb_(5)Si_(3) phase becomes refined and more discontinuous after adding minor *** for the fracture toughness,0.05 at% and 0.15 at% Sr additions do not cause significant *** discontinuous and refining mechanism of Sr element was studied,and the analysis of toughness decreasing with Sr addition reveals that the size of Nb_(ss) phase plays a crucial role in determining the fracture toughness.

关键词： Nb-Si alloy Refinement Discontinuous Fracture toughness Nb_(ss)