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Significance of highly phosphorylated insulin-like growth factor binding protein-1 and cervical length for prediction of preterm delivery in twin pregnancies

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World Journal of Clinical Cases 2021年第18期9卷 4553-4558页

作者： Rui-Hong Lan Jie Song Hu-Min Gong Yang Yang Hong Yang lin-mei zheng Department of Obstetrics Hainan General HospitalHainan Affiliated Hospital of Hainan Medical UniversityHaikou 570311Hainan ProvinceChina

BACKGROUND A twin pregnancy can carry greater risks than singleton *** 60 in 100 twin pregnancies result in spontaneous birth before 37 wk,which is associated with several complications in the premature *** detection of biomarkers may help to predict the possibility of premature birth so that corresponding interventions can be given to the pregnant women in a timely manner,in order to reduce the risk of preterm birth and improve the outcomes of the newborn *** To explore the clinical value of transvaginal ultrasound measurement of cervical length combined with insulin-like growth factor binding protein-1(IGFBP-1)hyperphosphorylation in cervical secretions as predictors of preterm delivery in twin *** A total of 254 pregnant women with twin pregnancies,who were admitted to Hainan General Hospital and underwent maternity examination,were selected as the study subjects from January 2015 to December *** participants received transvaginal ultrasound measurement of cervical length and phosphorylated IGFBP-1(phIGFBP-1)test between 24 and 34 wk *** pregnancy outcomes were *** Of the women with a positive phIGFBP-1 test result,preterm birth rate was higher in those with a cervical length≤25 mm than those with a cervical length>25 mm(all P25 mm(all P<0.05).The sensitivity,specificity,and positive and negative predictive values of the phIGFBP-1 test combined with the cervical length test were 95.71%,91.21%,95.12%and 92.22%,respectively,for the prediction of preterm *** Cervical length combined with phIGFBP-1 tests is of value for the prediction of outcomes of preterm delivery in twin pregnancies.

关键词： Hyperphosphorylated insulin-like growth factor binding protein-1 Cervical length Ultrasound Twin pregnancies Preterm delivery

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变线圈长度组织在毛衫设计中的应用

毛纺科技 2008年第4期36卷 45-48页

作者：姚晓林林美峥广东惠州学院服装系广东惠州516015

文章分析了变线圈长度组织的形成方法和形式,针对其影响因素、操作时应注意的问题以及存在的不足进行了探讨。结合羊毛衫设计中的设计要素,分析了变线圈长度组织在毛衫设计中的运用。对服装企业在产品设计和生产中的传统组织创新,组织... 详细信息

文章分析了变线圈长度组织的形成方法和形式,针对其影响因素、操作时应注意的问题以及存在的不足进行了探讨。结合羊毛衫设计中的设计要素,分析了变线圈长度组织在毛衫设计中的运用。对服装企业在产品设计和生产中的传统组织创新,组织设计与产品整体设计结合,设计出艺术风格独特的产品具有一定意义。

关键词：羊毛衫变线圈长度组织设计应用

牙隐裂患者咬合特征及牙体磨耗特点的临床观察

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中华口腔医学杂志 2009年第9期44卷 520-523页

作者：陈宇林正梅凌均棨中山大学光华口腔医学院附属口腔医院牙体牙髓科中山大学口腔医学研究所广东广州510055

目的分析牙隐裂患者的咬合特征，观察牙隐裂患牙的牙体磨耗情况，以期从骀学角度探讨牙隐裂的病因及咬合异常、牙体磨耗与牙隐裂之间的关系。方法选择27例牙隐裂患者的27颗患牙作为受试对象，应用T-ScanⅢ咬合分析仪对其进行正中、侧方... 详细信息

目的分析牙隐裂患者的咬合特征，观察牙隐裂患牙的牙体磨耗情况，以期从骀学角度探讨牙隐裂的病因及咬合异常、牙体磨耗与牙隐裂之间的关系。方法选择27例牙隐裂患者的27颗患牙作为受试对象，应用T-ScanⅢ咬合分析仪对其进行正中、侧方及前伸咬合记录，以27颗牙隐裂患牙为牙隐裂组，患牙毗邻的健康牙为正常对照组，分析两组的早接触、胎干扰、患者骀力中心位置等咬合特征，并按照牙体磨耗的Smith分级标准记录牙隐裂组与正常对照组的牙体磨耗程度并进行比较。结果牙隐裂组存在骀干扰的牙数（20颗）多于正常对照组（6颗），差异有统计学意义（OR=5.67，X^2=8.45，P=0.003）。24例单颗牙牙隐裂患者中牙尖交错位时[牙][合]力中心位于内侧椭圆以内和外侧椭圆以内（包含内侧椭圆）的分别为6例（25％）和18例（75％），经Z检验两者与正常对照组相比差异均有统计学意义（Z1=4.53，Z2=4.55，P〈0.05）。牙隐裂组中有侧方[牙][合]干扰的隐裂患牙存在牙体磨耗的比例高于无侧方[牙][合]干扰隐裂患牙，差异有统计学意义（X^2=4.79，P=0.029）。结论本组患者牙隐裂的发生与咬合异常有关，与牙体磨耗相关。

关键词：牙裂综合征牙磨耗咬合接触

广东珠江三角洲地区人下颌第一前磨牙根管解剖形态的研究

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华西口腔医学杂志 2008年第5期26卷 526-530页

作者：林正梅方溢云凌均棨中山大学光华口腔医学院·附属口腔医院牙体牙髓科广东广州510055 佛山市第一人民医院口腔医学中心广东佛山528000

目的通过普通X线片法、牙科手术显微镜下探查结合插诊断丝拍片法以及透明标本法,了解广东珠江三角洲地区人下颌第一前磨牙根管系统解剖特征。方法筛选出广东珠江三角洲地区人离体下颌第一前磨牙363颗为研究对象。将离体牙拍摄颊舌向、... 详细信息

目的通过普通X线片法、牙科手术显微镜下探查结合插诊断丝拍片法以及透明标本法,了解广东珠江三角洲地区人下颌第一前磨牙根管系统解剖特征。方法筛选出广东珠江三角洲地区人离体下颌第一前磨牙363颗为研究对象。将离体牙拍摄颊舌向、近远中向数字化X线片,初步判断根管数目。将离体牙开髓,采用牙科手术显微镜下观察法和离体牙透明标本法,观察并记录各牙齿的根管数目、类型。结果不同研究方法所得结果不同。普通X线片法多根管发现率为7.71%;牙科手术显微镜下探查结合插诊断丝拍片法多根管发现率为33.33%;透明标本法显示多根管发生率为34.44%,其中双根管27.82%,三根管5.79%,四根管0.83%。根管类型多样化,出现Vertuc-ci分类Ⅱ、Ⅲ、Ⅳ、Ⅴ及附加型(3-1)等。双根管的下颌第一前磨牙的髓底图特征为颊舌向直线,三、四根管下颌第一前磨牙的髓底图呈平台状。结论广东珠江三角洲地区人下颌第一前磨牙多根管出现率高,根管类型多样。牙科手术显微镜下探查法和插诊断丝拍片法结合,能够较为准确地判断下颌第一前磨牙的根管数目和类型。

关键词：下颌前磨牙根管解剖形态根管治疗

Multi-model ensemble learning for battery state-of-health estimation:Recent advances and perspectives

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Journal of Energy Chemistry 2025年第1期100卷 739-759页

作者： Chuanping lin Jun Xu Delong Jiang Jiayang Hou Ying Liang Zhongyue Zou Xuesong mei State Key Laboratory for Manufacturing Systems Engineering Xi'an Jiaotong University Shaanxi Key Laboratory of Intelligent Robots School of Mechanical Engineering Xi'an Jiaotong University Department of Electrical Engineering and Automation Luoyang Institute of Science and Technology School of Mechanical Engineering Hangzhou Dianzi University

The burgeoning market for lithium-ion batteries has stimulated a growing need for more reliable battery performance monitoring. Accurate state-of-health(SOH) estimation is critical for ensuring battery operational performance. Despite numerous data-driven methods reported in existing research for battery SOH estimation, these methods often exhibit inconsistent performance across different application scenarios. To address this issue and overcome the performance limitations of individual data-driven models,integrating multiple models for SOH estimation has received considerable attention. Ensemble learning(EL) typically leverages the strengths of multiple base models to achieve more robust and accurate outputs. However, the lack of a clear review of current research hinders the further development of ensemble methods in SOH estimation. Therefore, this paper comprehensively reviews multi-model ensemble learning methods for battery SOH estimation. First, existing ensemble methods are systematically categorized into 6 classes based on their combination strategies. Different realizations and underlying connections are meticulously analyzed for each category of EL methods, highlighting distinctions, innovations, and typical applications. Subsequently, these ensemble methods are comprehensively compared in terms of base models, combination strategies, and publication trends. Evaluations across 6 dimensions underscore the outstanding performance of stacking-based ensemble methods. Following this, these ensemble methods are further inspected from the perspectives of weighted ensemble and diversity, aiming to inspire potential approaches for enhancing ensemble performance. Moreover, addressing challenges such as base model selection, measuring model robustness and uncertainty, and interpretability of ensemble models in practical applications is emphasized. Finally, future research prospects are outlined, specifically noting that deep learning ensemble is poised to advance ens

关键词： Lithium-ion battery State-of-health estimation Data-driven Machine learning Ensemble learning Ensemble diversity

Effect of cholesterol metabolism on hepatolithiasis

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World Journal of Gastroenterology 2025年第1期31卷 157-162页

作者： lin zheng Zi-Yu Ye Jun-Ji Ma Department of Gastroenterology The Second Hospital of Hebei Medical UniversityHebei Key Laboratory of GastroenterologyHebei Institute of GastroenterologyHebei Clinical Research Center for Digestive DiseasesNo.215 Heping West RoadShijiazhuang 050000Hebei ProvinceChina

Surgical intervention is currently the primary treatment for hepatolithiasis;how-ever,some patients still experience residual stones and high recurrence rates after *** metabolism seems to play an important role in hepatoli-thiasis pathogenesis.A high cholesterol diet is one of the significant reasons for the increasing incidence of ***,regular diet and appropriate medical intervention are crucial measures to prevent hepatolithiasis and reduce recurrence rate after *** dietary cholesterol and drugs that increase cholesterol stone solubility are key therapeutic approaches in treating *** article discusses the cholesterol metabolic pathways related to the pathogenesis of hepatolithiasis,as well as food intake and targeted therapeutic drugs.

关键词： Hepatolithiasis Cholesterol metabolism High-fat diet 3-hydroxy-3-methylglutaryl-coenzyme A reductase Interlobular bile duct

Pyroptosis,ferroptosis,and autophagy in spinal cord injury:regulatory mechanisms and therapeutic targets

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Neural Regeneration Research 2025年第10期20卷 2787-2806页

作者： Qingcong zheng Du Wang Rongjie lin Weihong Xu Department of Spinal Surgery the First Affiliated Hospital of Fujian Medical UniversityFuzhouFujian ProvinceChina Arthritis Clinical and Research Center Peking University People’s HospitalBeijingChina Department of Orthopedic Surgery Fujian Medical University Union HospitalFuzhouFujian ProvinceChina

Regulated cell death is a form of cell death that is actively controlled by *** studies have shown that regulated cell death plays a key role after spinal cord *** and ferroptosis are newly discovered types of regulated cell deaths that have been shown to exacerbate inflammation and lead to cell death in damaged spinal ***,a complex form of cell death that is interconnected with various regulated cell death mechanisms,has garnered significant attention in the study of spinal cord *** injury triggers not only cell death but also cellular survival *** signaling pathways play pivotal roles in influencing the processes of both deterioration and repair in spinal cord injury by regulating pyroptosis,ferroptosis,and ***,this review aims to comprehensively examine the mechanisms underlying regulated cell deaths,the signaling pathways that modulate these mechanisms,and the potential therapeutic targets for spinal cord *** analysis suggests that targeting the common regulatory signaling pathways of different regulated cell deaths could be a promising strategy to promote cell survival and enhance the repair of spinal cord ***,a holistic approach that incorporates multiple regulated cell deaths and their regulatory pathways presents a promising multi-target therapeutic strategy for the management of spinal cord injury.

关键词： autophagy cell death ferroptosis inflammation pathological mechanisms pyroptosis regulated cell death regulatory pathways spinal cord injury therapeutic targets

新型双甲基丙烯酸酯树脂根管封闭剂的制备与理化特性评价

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中山大学学报（自然科学版） 2007年第2期46卷 49-54页

作者：林正梅凌均棨刘芳何经纬贾德民中山大学光华口腔医学院∥口腔医学研究所广东广州510060 华南理工大学材料科学与工程学院广东广州510641

以9,9′-二-(4-羟基-苯基)芴(9′9-HPF)为原料,用环氧氯丙烷将其环氧化后,再与甲基丙烯酸反应,合成了相对分子质量为634的双甲基丙烯酸酯类新单体HPFDM,并以该单体为共聚单体制备了新型树脂基质根管封闭剂NRCS。通过对其聚合收缩、体积... 详细信息

以9,9′-二-(4-羟基-苯基)芴(9′9-HPF)为原料,用环氧氯丙烷将其环氧化后,再与甲基丙烯酸反应,合成了相对分子质量为634的双甲基丙烯酸酯类新单体HPFDM,并以该单体为共聚单体制备了新型树脂基质根管封闭剂NRCS。通过对其聚合收缩、体积改变和溶解性能的测定,以及用扫描电镜观察它在水介质中浸泡前后表面形貌的变化,评价了封闭剂NRCS的理化特性。结果表明:HPFDM的结构与预期设计的结构相符,新型封闭剂NRCS的聚合收缩率为1.375%,体积变化率为1.16%,在水介质中的质量损失为0.15%,扫描电子显微镜观察显示封闭剂NRCS表面结构均质致密,填料粒子较好地分散在基体中,界面结合良好,水介质处理对封闭剂影响不明显。

关键词：根管封闭剂高相对分子质量甲基丙烯酸酯 Bis—GMA 环氧树脂 9,9’-二-(4-羟基-苯基)芴(9’9-HPF) 理化特性

HLA-G14 bp polymorphism Hainan Li nationality and severe preeclampsia susceptibility related research

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Journal of Hainan Medical University 2020年第12期26卷 20-23页

作者： Li Wang Xue Wang Xiao-Ju Chen Hui Cen Dong-Cai Wu Yu-Qiao Mo Dong-Rui Mao lin-mei zheng Hainan Provincial People s HospitalHainan Hospital Affiliated to Hainan Medical University Department of Obstetrics Emergency Internal MedicineHainan Haikou 570013China

Objective:To explore the correlation between the distribution of 14bp polymorphism in exon 8 of human leukocyte antigen-G(HLA-G)gene in Hainan Li nationality and susceptibility to severe ***:100 cases of severe preeclampsia inpatients(experimental group)admitted to our hospital from June 2018 to September 2019 were *** them,50 were Li and 50 were Han,and 100 were admitted to our hospital during the same period Normal pregnant women were the control group,including 50 cases of Li nationality and 50 cases of Han *** blood was collected to detect the 14bp polymorphism in HLA-G gene exon 8,and the correlation between the 14bp polymorphism in HLA-G gene exon 8 and susceptibility to severe preeclampsia was ***:There was a statistically significant difference in the 14-bp genotyping and allele frequency in HLA-G exon 8 of the Li ethnic group in the control group and the experimental group(P<0.05).The SBP and DBP of the Li 14-14/14bp typing,+14bp/-14bp typing,and allele-14bp typing were lower in the experimental group than in the Han group in the experimental group(P<0.05),and the SBP of+14bp/-14bp typing DBP was higher than that of Han patients in the experimental group(P<0.05).Binary Logistic Regression Analysis+14bp/-14bp was associated with the incidence of severe preeclampsia in Li women in Hainan region(P<0.05).The-14bp/-14bp classification was a protective factor for severe preeclampsia in Li women in Hainan region(P<0.05).Conclusion:The HLA-G gene exon 8 carrying a 14bp deletion polymorphism in the Hainan Li nationality is associated with preeclampsia susceptibility and progression.

关键词： Human leukocyte antigen-G Exon 8 14bp polymorphism Severe preeclampsia Susceptibility correlation