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Al_2O_3-SiO_2-TiO_2表面涂层对3D-C_f/SiC复合材料力学性能的影响

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人工晶体学报 2018年第3期47卷 489-493页

作者：张善伟林文松王静静方宁象傅肃嘉上海工程技术大学材料科学与工程学院上海201620 浙江立泰复合材料股份有限公司湖州313219

采用溶胶凝胶法在三维碳纤维预制体(3D-Cf)表面形成Al2O3-SiO_2-TiO_2涂层,而后采用先驱体浸渍裂解工艺(PIP)制备了3D-Cf/Si C复合材料,通过SEM、XRD等分析测试手段以及三点弯曲等试验方法,研究了碳纤维的界面对复合材料的微观结构、力... 详细信息

采用溶胶凝胶法在三维碳纤维预制体(3D-Cf)表面形成Al2O3-SiO_2-TiO_2涂层,而后采用先驱体浸渍裂解工艺(PIP)制备了3D-Cf/Si C复合材料,通过SEM、XRD等分析测试手段以及三点弯曲等试验方法,研究了碳纤维的界面对复合材料的微观结构、力学性能的影响。结果表明,Al2O3-SiO_2-TiO_2涂覆处理后的碳纤维的强度约为原始碳纤维的96.8%,涂层碳纤维在复合材料断裂过程中起到了较好的增韧作用,涂层处理后的3D-Cf/Si C复合材料的抗弯强度达303 MPa,断裂韧度达6.5 MPa/m1/2。

关键词：三维碳纤维 Al2O3-SiO2-TiO2涂层 Cf/SiC复合材料力学性能

电喷镀Ni-纳米PTFE复合镀层工艺的研究

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热处理 2007年第3期22卷 34-37,44页

作者：林文松王伟何庆如宋婕上海工程技术大学材料科学与工程学院上海201620

采用高速电喷镀技术制备Ni-纳米PTFE复合镀层。研究了分散形式和喷镀工艺对纳米PTFE颗粒在电喷镀液中均匀稳定分散及镀覆过程的影响,采用扫描电子显微镜(SEM)、电子探针微区成分分析仪(EPM)、红外光谱等方法研究了纳米PTFE在复合镀层中... 详细信息

采用高速电喷镀技术制备Ni-纳米PTFE复合镀层。研究了分散形式和喷镀工艺对纳米PTFE颗粒在电喷镀液中均匀稳定分散及镀覆过程的影响,采用扫描电子显微镜(SEM)、电子探针微区成分分析仪(EPM)、红外光谱等方法研究了纳米PTFE在复合镀层中的存在形式和镀层的形貌特征。结果表明,分散剂在PTFE的分散过程中起着重要作用,PTFE颗粒以纳米尺度均匀分布于镀层基体中。

关键词：电喷镀复合镀纳米FFFE 分散

Mechanism of action of linggui Zhugan Decoction in treating non-alcoholic fatty liver disease using untargeted metabolomics approach

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Traditional Medicine Research 2025年第2期10卷 65-76页

作者： Huan Pei Ren-lin Li Xin-Ran song Qian-Qian Wan Yu-Ming Wang Han-Zhou Li Wei-Quan Xu Jia-Bao Liao Wei-Bo wen Jing Miao Huan-Tian Cui School of Basic Medicine Yunnan University of Chinese MedicineKunming 650599China School Clinical Medical College Yunnan University of Chinese MedicineKunming 650599China First School of Clinical Medicine Yunnan University of Chinese MedicineKunming 650599China School of Integrative Chinese and Western Medicine Tianjin University of Traditional Chinese MedicineTianjin 301617China Department of Pharmacy Tianjin Second People's HospitalTianjin 300192China

Background:Non-alcoholic fatty liver disease(NAFLD)is a liver disorder characterized by the accumulation and degeneration of fat in the liver cells,a condition that may further deteriorate and lead to cirrhosis and liver *** studies showed that metabolic dysfunction can promote NAFLD *** Zhugan Decoction(LGZGD)has therapeutic effects on *** mechanism of LGZGD still remains *** study was to examine the impact of LGZGD on the metabolic processes involved in the development of ***:A mice model of NAFLD was treated with *** therapeutic potential of LGZGD was evaluated by assessing the activity of transaminases,lipids levels of blood,and pathological changes in the liver of the mice model of ***,this study also evaluated the influence of LGZGD on liver inflammation and oxidative ***:The results of untargeted metabolomics analysis showed that LGZGD reduced the disordered lipid metabolism in NAFLD *** improved the oxidative stress and also reduced the levels of pro-inflammatory cytokines in the *** metabolomics analysis of liver samples revealed that LGZGD treatment improved metabolic disorders,including alanine,aspartate,glutamate,glycerophospholipid metabolism,and citrate *** RT-qPCR and Western blot results showed that LGZGD could regulate the expression of key enzymes in the metabolic pathway of the citrate cycle,including ATP-citrate lyase(ACLY),alanine-glyoxylate aminotransferase-2(AGXT2),phosphatidylethanolamine N-methyltransferase(PEMT),and succinate dehydrogenase(SDH).Conclusion:We found that LGZGD can treat NAFLD by reducing inflammatory responses,inhibiting oxidative stress,regulating alanine,aspartate,glutamate,and glycerophospholipid metabolism,and citrate cycle pathways.

关键词： NAFLD LGZGD untargeted metabolomics glycerophospholipid metabolism citrate cycle

A Flexible Smart Healthcare Platform Conjugated with Artificial Epidermis Assembled by Three‑Dimensionally Conductive MOF Network for Gas and Pressure Sensing

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Nano-Micro Letters 2025年第2期17卷 601-620页

作者： Qingqing Zhou Qihang Ding Zixun Geng Chencheng Hu Long Yang Zitong Kan Biao Dong Miae Won Hongwei song lin Xu Jong Seung Kim State Key Laboratory of Integrated Optoelectronics College of Electronic Science and EngineeringJilin UniversityChangchun 130012People’s Republic of China Department of Chemistry Korea UniversitySeoul 02841Republic of Korea TheranoChem Incorporation Seoul 02856Republic of Korea

The rising flexible and intelligent electronics greatly facilitate the noninvasive and timely tracking of physiological information in telemedicine *** building bionic-sensitive moieties is vital for designing efficient electronic skin with advanced cognitive functionalities to pluralistically capture external ***,realistic mimesis,both in the skin’s three-dimensional interlocked hierarchical structures and synchronous encoding multistimuli information capacities,remains a challenging yet vital need for simplifying the design of flexible logic ***,we construct an artificial epidermal device by in situ growing Cu_(3)(HHTP)_(2) particles onto the hollow spherical Ti_(3)C_(2)T_(x) surface,aiming to concurrently emulate the spinous and granular layers of the skin’s *** bionic Ti_(3)C_(2)T_(x)@Cu_(3)(HHTP)_(2) exhibits independent NO_(2) and pressure response,as well as novel functionalities such as acoustic signature perception and Morse code-encrypted message ***,a wearable alarming system with a mobile application terminal is self-developed by integrating the bimodular senor into flexible printed *** system can assess risk factors related with asthmatic,such as stimulation of external NO_(2) gas,abnormal expiratory behavior and exertion degrees of fingers,achieving a recognition accuracy of 97.6%as assisted by a machine learning *** work provides a feasible routine to develop intelligent multifunctional healthcare equipment for burgeoning transformative telemedicine diagnosis.

关键词： Ti_(3)C_(2)T_(x)@Cu_(3)(HHTP)_(2)composites NO_(2)/pressure flexible sensors Health-monitoring Machine learning

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反应烧结制备碳化硅-氮化铝复合材料

硅酸盐通报 2016年第3期35卷 682-685页

作者：闫学增吴晓杨亚云林文松王静静上海工程技术大学材料工程学院上海201620

采用硅作为熔渗剂,利用真空反应烧结的工艺,在1600℃烧结制得了结构致密、密度低的碳化硅-氮化铝(Si C/AlN)复合材料,分析测试了所制得的复合材料的物相、微观结构和力学性能。结果表明,氮化铝的添加量由2wt%增加到10wt%时,复合材料的... 详细信息

采用硅作为熔渗剂,利用真空反应烧结的工艺,在1600℃烧结制得了结构致密、密度低的碳化硅-氮化铝(Si C/AlN)复合材料,分析测试了所制得的复合材料的物相、微观结构和力学性能。结果表明,氮化铝的添加量由2wt%增加到10wt%时,复合材料的力学性能出现先增加后减小的趋势,当AlN含量为6wt%时,得到复合材料的力学性能最高,其抗弯强度为256 MPa,显微硬度为2660 HV。加入AlN后,复合材料的孔隙率略微有点上升,烧结体的密度在2.95~3.01 g/cm^3之间。复合材料的主要组成相为Si C、AlN和Si。

关键词：氮化铝碳化硅反应烧结熔渗

Infiltration by monocytes of the central nervous system and its role in multiple sclerosis: reflections on therapeutic strategies

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Neural Regeneration Research 2025年第3期20卷 779-793页

作者： Guangyong Zhang Qing Yao Chubing Long Pengcheng Yi Jiali song Luojia Wu Wei Wan Xiuqin Rao Yue lin Gen Wei Jun Ying Fuzhou Hua Department of Anesthesiology the Second Affiliated Hospital of Nanchang UniversityNanchangJiangxi ProvinceChina Key Laboratory of Anesthesiology of Jiangxi Province NanchangJiangxi ProvinceChina

Mononuclear macrophage infiltration in the central nervous system is a prominent feature of neuroinflammation. Recent studies on the pathogenesis and progression of multiple sclerosis have highlighted the multiple roles of mononuclear macrophages in the neuroinflammatory process. Monocytes play a significant role in neuroinflammation, and managing neuroinflammation by manipulating peripheral monocytes stands out as an effective strategy for the treatment of multiple sclerosis, leading to improved patient outcomes. This review outlines the steps involved in the entry of myeloid monocytes into the central nervous system that are targets for effective intervention: the activation of bone marrow hematopoiesis, migration of monocytes in the blood, and penetration of the blood–brain barrier by monocytes. Finally, we summarize the different monocyte subpopulations and their effects on the central nervous system based on phenotypic differences. As activated microglia resemble monocyte-derived macrophages, it is important to accurately identify the role of monocyte-derived macrophages in disease. Depending on the roles played by monocyte-derived macrophages at different stages of the disease, several of these processes can be interrupted to limit neuroinflammation and improve patient prognosis. Here, we discuss possible strategies to target monocytes in neurological diseases, focusing on three key aspects of monocyte infiltration into the central nervous system, to provide new ideas for the treatment of neurodegenerative diseases.

关键词： blood–brain barrier macrophages monocytes multiple sclerosis neuroinflammation review therapy