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Journal of Geriatric Cardiology 2024年第1期21卷 64-80页

作者： Xiong-Bin MA Yong-Ming LIU Yan-lin LV lin qian The First Clinical Medical College of Lanzhou University LanzhouGansuChina Geriatric Cardiovascular Department and Gansu Clinical Research Center for Geriatric Diseases First Hospital of Lanzhou UniversityGansuChina

BACKGROUND Left ventricular(LV)remodeling and diastolic function in people with heart failure(HF)are correlated with iron status;however,the causality is *** Mendelian randomization(MR)study investigated the bidirectional causal relationship between systemic iron parameters and LV structure and function in a preserved ejection fraction *** Transferrin saturation(TSAT),total iron binding capacity(TIBC),and serum iron and ferritin levels were extracted as instrumental variables for iron parameters from meta-analyses of public genome-wide association *** without myocardial infarction history,HF,or LV ejection fraction(LVEF)ling and function in a preserved ejection fraction population.

关键词： fraction function parameters

Equilibrium Reinsurance Strategy and Mean Residual Life Function

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Acta Mathematicae Applicatae Sinica 2024年第3期40卷 758-777页

作者： Dan-ping LI Lv CHEN lin-yi qian Wei WANG School of Statistics Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOEEast China Normal UniversityShanghai 200062China Academy of Statistics and Interdisciplinary Sciences Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOEEast China Normal UniversityShanghai 200062China School of Mathematics and Statistics Ningbo UniversityNingbo 315211China

In this paper,we analyze the relationship between the equilibrium reinsurance strategy and the tail of the distribution of the *** Mean Residual Life(MRL)has a close relationship with the tail of the distribution,we consider two classes of risk distributions,Decreasing Mean Residual Life(DMRL)and Increasing Mean Residual Life(IMRL)distributions,which can be used to classify light-tailed and heavy-tailed distributions,*** assume that the underlying risk process is modelled by the classical CramérLundberg model *** the mean-variance criterion,by solving the extended Hamilton-Jacobi-Bellman equation,we derive the equilibrium reinsurance strategy for the insurer and the reinsurer under DMRL and IMRL,***,we analyze how to choose the reinsurance premium to make the insurer and the reinsurer agree with the same reinsurance *** find that under the case of DMRL,if the distribution and the risk aversions satisfy certain conditions,the insurer and the reinsurer can adopt a reinsurance premium to agree on a reinsurance strategy,and under the case of IMRL,the insurer and the reinsurer can only agree with each other that the insurer do not purchase the reinsurance.

关键词： mean residual life excess-of-loss reinsurance insurer reinsurer stochastic control

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Optical modification of nonlinear crystals for quasi-parametric chirped-pulse amplification

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Fundamental Research 2024年第1期4卷 43-50页

作者： qian lin Jingui Ma Zhe Yin Peng Yuan Jing Wang Guoqiang Xie Liejia qian Key Laboratory for Laser Plasmas(MOE) Collaborative Innovation Center of IFSASchool of Physics and AstronomyShanghai Jiao Tong UniversityShanghai 200240China Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghai 200240China

Quasi-parametric chirped-pulse amplification(QPCPA),which features a theoretical peak power much higher than those obtained with Ti:sapphire laser or optical parametric chirped-pulse amplification,is promising for future ultra-intense *** doped rare-earth ion used for idler dissipation is critical for effective QPCPA,but is usually not compatible with traditional *** far,only one dissipative crystal of Sm^(3+)-doped yttrium calcium oxyborate has been grown and *** we introduce optical means to modify traditional crystals for QPCPA *** theoretically demonstrate two dissipation schemes by idler frequency doubling and sum-frequency generation with an additional *** contrast to absorption dissipation,the proposed nonlinear dissipations ensure not only high signal efficiency but also high small-signal *** demonstrated ability to optically modify crystals will facilitate the wide application of QPCPA.

关键词： Quasi-parametric amplifier Second-harmonic generation Sum-frequency generation Back conversion Idler dissipation

Rhodium-catalyzed Doyle-Kirmse rearrangement reactions of sulfoxoniun ylides

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Chinese Chemical Letters 2024年第4期35卷 363-366页

作者： Ying-Di Hao Zhi-qian lin Xiao-Yu Guo Jiao Liang Can-Kun Luo qian-Tao Wang Li Guo Yong Wu Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Department of Medicinal Chemistry Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial TechnologyWest China School of PharmacySichuan UniversityChengdu 610041China

Doyle-Kirmse rearrangement reactions have received continuous attention as an important method for constructing complex chemical structures. Herein, we disclosed an efficient rhodium-catalyzed DoyleKirmse rearrangement reaction, which can simultaneously construct C–C bonds and C–X(X = S/Se) bonds using sulfoxonium ylides as starting materials to obtain sulfur-or selenium-containing compounds. This strategy is characterized by the safer and greener carbene precursor, high yields and broad substrate scope, possessing a wide range of application.

关键词： Sulfoxonium ylides Rhodium(Ⅱ)-catalyzed Carbene Rearrangement reactions One-pot process

Spin of Micro-Propeller Structures Driven by High-Order Poincaré Beams

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激光与光电子学进展 2024年第5期61卷 572-577页

作者： lin qian Chen Lei Zhuang Zikuan Sun Jingxuan Zhang Li Xie Jianing Guangdong-Hong Kong-Macao Joint Laboratory for Intelligent Micro-Nano Optoelectronic Technology Foshan UniversityFoshan 528225GuangdongChina

The use of light-induced micro-motors or micro-propellers,showcasing non-contact and non-damaging characteristics,is garnering increased attention in biomedical,micro-machine,and environmental *** High-order Poincaré(HOP)beam,as a vector beam,provides a controllable driving force with adjustable orbital angular momentum and spin angular *** this study,we present the spin of a self-assembled micro-propeller structure propelled by the HOP beam,enabling flexible control over rotation velocity and *** findings reveal that modifications to the total angular momentum of the driving beam field or alterations in the micro-propeller blade structure can influence rotation *** research offers an efficient and versatile approach for applications in optical micromanipulation and micromachinery.

关键词： high-order Poincarébeam self-assemble propeller micro-propeller

Application of neutrophil-lymphocyte ratio and red blood cell distribution width in diabetes mellitus complicated with heart failure

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World Journal of Diabetes 2024年第6期15卷 1226-1233页

作者： Jie Pang lin-Yan qian Ping Lv Xiao-Ru Che Heart Center Department of Cardiovascular MedicineZhejiang Provincial People’s Hospital(The Affiliated People’s Hospital)Hangzhou Medical CollegeHangzhou 310014Zhejiang ProvinceChina

BACKGROUND Accumulating clinical evidence has shown that diabetes mellitus(DM)is a serious risk factor for cardiovascular disorders and an important factor for adverse cardiovascular *** To explore the value of the combined determination of the neutrophil-lymphocyte ratio(NLR)and red blood cell distribution width(RDW)in the early diagnosis and prognosis evaluation of DM complicated with heart failure(HF).METHODS We retrospectively analyzed clinical data on 65 patients with type 2 DM(T2DM)complicated with HF(research group,Res)and 60 concurrent patients with uncomplicated T2DM(control group,Con)diagnosed at Zhejiang Provincial People’s Hospital between January 2019 and December *** NLR and RDW values were determined and comparatively analyzed,and their levels in T2DM+HF patients with different cardiac function grades were *** receiver operating characteristic(ROC)curves were plotted to determine the NLR and RDW values(alone and in combination)for the early diagnosis of *** correlation between NLR and RDW with the presence or absence of cardiac events was also *** Higher NLR and RDW levels were identified in the Res vs the Con groups(P<0.05).The NLR and RDW increased gradually and synchronously with the deterioration of cardiac function in the Res group,with marked differences in their levels among patients with grade II,III,and IV HF(P<0.05).ROC curve analysis revealed that NLR combined with RDW detection had an area under the curve of 0.915,a sensitivity of 76.9%,and a specificity of 100%for the early diagnosis of ***,HF patients with cardiac events showed higher NLR and RDW values compared with HF patients without cardiac *** NLR and RDW were useful laboratory indicators for the early diagnosis of DM complicated with HF,and their joint detection was beneficial for improving diagnostic ***,NLR and RDW values were directly proportional to patient outcomes.

关键词： Neutrophil-lymphocyte ratio Red blood cell distribution width Type 2 diabetes Heart failure Early diagnosis

Diarrhea induced by insufficient fat absorption in weaned piglets:Causes and nutrition regulation

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Animal Nutrition 2024年第01期16卷 299-305页

作者： Yuying Li Pengjun Shi Kang Yao qian lin Mansheng Wang Zhenping Hou Wenjie Tang Hui Diao Institute of Bast Fiber Crops Chinese Academy of Agricultural Sciences Institute of Subtropical Agriculture Chinese Academy of Sciences Hunan Province Key Laboratory of Animal Nutritional Physiology and Metabolic Process Animal Breeding and Genetics Key Laboratory of Sichuan Province Livestock and Poultry Biological Products Key Laboratory of Sichuan Province Sichuan Animal Science Academy Sichuan Animtech Feed Co. Ltd

Fat is one of the three macronutrients and a significant energy source for piglets. It plays a positive role in maintaining intestinal health and improving production performance. During the weaning period,physiological, stress and diet-related factors influence the absorption of fat in piglets, leading to damage to the intestinal barrier, diarrhea and even death. Signaling pathways, such as fatty acid translocase(CD36), pregnane X receptor(PXR), and AMP-dependent protein kinase(AMPK), are responsible for regulating intestinal fat uptake and maintaining intestinal barrier function. Therefore, this review mainly elaborates on the reasons for diarrhea induced by insufficient fat absorption and related signaling pathways in weaned-piglets, with an emphasis on the intestinal fat absorption disorder. Moreover, we focus on introducing nutritional strategies that can promote intestinal fat absorption in piglets with insufficient fat absorption-related diarrhea, such as lipase, amino acids, and probiotics.

关键词： Weaned piglet Diarrhea Fat absorption Nutrient regulation

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境界与空谈——论早期佛教对形而上学的态度

世界宗教文化 2024年第2期 145-152页

作者：林乾青岛大学历史学院

一般认为,佛教有自己的哲学体系和形而上学作为其实践的基础。本文探讨早期佛教经典中“境界”(visaya/visaya)的概念,说明“境界”既代表经验的领域,同时也是语言的作用域或框架是一一一个词只在它自己的领域内才有指称作用,而在这个... 详细信息

一般认为,佛教有自己的哲学体系和形而上学作为其实践的基础。本文探讨早期佛教经典中“境界”(visaya/visaya)的概念,说明“境界”既代表经验的领域,同时也是语言的作用域或框架是一一一个词只在它自己的领域内才有指称作用,而在这个语义框架之外则是无意义的。早期佛教在这一点上与逻辑实证主义哲学家鲁道夫·卡尔纳普(Rudolf Carnap)的“语言框架”的主张非常相似。卡尔纳普认为相对于语言框架的外部问题(即形而上学问题)没有意义,无法给予直接的肯定或否定回答。佛经中佛陀拒绝回答所谓“无记”的问题也类似于卡尔纳普拒绝形而上学的态度。诸如“无常”“缘起”等教义尽管在现代读者看来属于形而上学的范畴,但在早期佛经中应该理解为对经验的描述,而不是形而上学。

关键词：早期佛教形而上学鲁道夫·卡尔纳普境界无记

ChatGPT赋能语文写作教学的价值、冲击及启示

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教学与管理 2024年第15期 63-66页

作者：朱琳阡湖州师范学院教师教育学院浙江湖州313000

ChatGPT生成式人工智能技术在教育领域掀起一阵狂潮,为语文写作教学带来了新的变革与创新。ChatGPT类生成式人工智能为学生写作提供个性化反馈并能优化学生写作素材,但ChatGPT在语文写作教学中的应用极易固化学生写作模式,禁锢学生写作... 详细信息

ChatGPT生成式人工智能技术在教育领域掀起一阵狂潮,为语文写作教学带来了新的变革与创新。ChatGPT类生成式人工智能为学生写作提供个性化反馈并能优化学生写作素材,但ChatGPT在语文写作教学中的应用极易固化学生写作模式,禁锢学生写作思维运转;蚕食学生写作主体性,引发学生写作主体移位;挑战学生写作诚信,造成教师写作评价失真等问题。为此,需要呵护学生写作主体,指引学生写作思维与能力发展;侧重过程性评价,防范写作诚信危机;坚持人机协同并进,推动语文写作教学变革,以期人工智能技术更好地为语文写作教学赋能,推动教育数字化转型升级。

关键词：语文写作教学 ChatGPT 人工智能人机协同教育数字化

基于温度特性测试的GaN HEMT功率放大器性能退化研究

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实验技术与管理 2024年第4期41卷 60-65页

作者：汪玫倩林倩青海民族大学物理与电子信息工程学院青海西宁810007 电子科技大学电子科学与工程学院四川成都610000 同方电子科技有限公司江西九江332000

为了研究氮化镓高电子迁移率晶体管功率放大器在不同环境温度下的性能退化情况,根据我国东、西、南、北4个地区的极端温度、平均温度以及电路的工作温度对其进行了系统的温度特性测试。测试结果显示,随着温度升高,该功率放大器的直流特... 详细信息

为了研究氮化镓高电子迁移率晶体管功率放大器在不同环境温度下的性能退化情况,根据我国东、西、南、北4个地区的极端温度、平均温度以及电路的工作温度对其进行了系统的温度特性测试。测试结果显示,随着温度升高,该功率放大器的直流特性和交流特性都出现了不同程度的退化,当温度升高至125℃时,小信号增益较常温减少了1.26 dB,三阶交调点下降了6.03 dBm,输出功率与增益最大差值为1.31 dB。分析可得其主要原因是温度升高直接引起阈值电压正向偏移和二维电子气迁移率下降,进而导致饱和电流减小和膝点电压增加,最终使得输出功率显著减小。为保证电路在不同温度下正常工作,提出了一种温度补偿措施来抵消由温度引起的性能退化,这为电路的可靠性设计提供了重要参考。

关键词： GaN HEMT 功率放大器温度特性温度补偿