检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

多轴数控加工技术在汽车零部件加工中的运用

科技资讯 2024年第18期22卷 105-107,123页

作者：马玉良梁海花广东省机械技师学院广东广州510450

随着现代生产技术的不断发展,多轴数控加工技术作为一种先进的机械制造方法,已经被广泛应用于汽车制造、航空航天、通信等行业。在汽车制造行业,多轴数控加工技术多用于柱面凸轮轴、发动机叶轮、汽车引擎等零部件的加工过程中,不仅可以... 详细信息

随着现代生产技术的不断发展,多轴数控加工技术作为一种先进的机械制造方法,已经被广泛应用于汽车制造、航空航天、通信等行业。在汽车制造行业,多轴数控加工技术多用于柱面凸轮轴、发动机叶轮、汽车引擎等零部件的加工过程中,不仅可以提高加工效率和精度,降低生产制造的成本,还能有效地提升汽车零部件的质量和性能,从而实现汽车零部件的高效和精确加工,推动汽车制造行业的智能化发展。

关键词：多轴数控加工技术汽车零部件自动化智能化应用价值加工运用

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

建筑地质岩土勘察与地基处理技术分析

中国厨卫 2024年第6期23卷 73-75页

作者：梁海华李有斌钦州市地质基础工程公司广西钦州535000

建筑工程涉及到众多特殊的地质结构,为保障建设安全,对地基提出了较高的要求。因此,在建筑工程施工中,应首先对地质岩土展开勘查,若发现地质质量不足,需及时采取相应的处理措施进行处理。基于此,文章对建筑地质岩土勘查内容、勘查现状... 详细信息

建筑工程涉及到众多特殊的地质结构,为保障建设安全,对地基提出了较高的要求。因此,在建筑工程施工中,应首先对地质岩土展开勘查,若发现地质质量不足,需及时采取相应的处理措施进行处理。基于此,文章对建筑地质岩土勘查内容、勘查现状展开了研究,并提出了不同地基处理技术,包括强夯、换填、预压、高压旋喷注浆,以期为建筑工程地基处理提供参考。

关键词：建筑工程地质岩土勘察地基处理

Quadratic perturbations of a class of quadratic reversible center of genus one

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Mathematics 2013年第3期56卷 577-596页

作者： liang haihua WU KuiLin ZHAO YuLin Department of Computer Science Guangdong Polytechnic Normal University College of Science Guizhou University Department of Mathematics Sun Yat-sen University

This paper is concerned with the quadratic perturbations of a one-parameter family of quadratic reversible system, having a center of genus one. The exact upper bound of the number of limit cycles emerging from the pe... 详细信息

关键词： quadratic perturbations quadratic reversible system limit cycle abelian integral

Pseudomonas aeruginosa:pathogenesis,virulence factors,antibiotic resistance,interaction with host,technology advances and emerging therapeutics

在线全文

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2022年第7期7卷 2396-2422页

作者： Shugang Qin Wen Xiao Chuanmin Zhou Qinqin Pu Xin Deng Lefu Lan haihua liang Xiangrong Song Min Wu Department of Critical Care Medicine Frontiers Science Center for Disease-related Molecular NetworkState Key Laboratory of Biotherapy and Cancer CenterWest China HospitalSichuan UniversityChengduChina State Key Laboratory of Virology School of Public HealthWuhan UniversityWuhan 430071P.R.China Department of Biomedical Sciences School of Medicine and Health SciencesUniversity of North DakotaGrand ForksND 58203USA Department of Biomedical Sciences City University of Hong KongHong KongPeople’s Republic of China State Key Laboratory of Drug Research Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China College of Life Sciences Northwest UniversityXi’anShaanXi 710069China

Pseudomonas aeruginosa(***)is a Gram-negative opportunistic pathogen that infects patients with cystic fibrosis,burn wounds,immunodeficiency,chronic obstructive pulmonary disorder(COPD),cancer,and severe infection requiring ventilation,such as *** is also a widely-used model bacterium for all biological *** addition to continued,intense efforts in understanding bacterial pathogenesis of *** including virulence factors(LPS,quorum sensing,two-component systems,6 type secretion systems,outer membrane vesicles(OMVs),CRISPR-Cas and their regulation),rapid progress has been made in further studying host-pathogen interaction,particularly host immune networks involving autophagy,inflammasome,noncoding RNAs,cGAS,***,numerous technologic advances,such as bioinformatics,metabolomics,scRNA-seq,nanoparticles,drug screening,and phage therapy,have been used to improve our understanding of *** pathogenesis and host ***,much remains to be uncovered about interactions between *** and host immune responses,including mechanisms of drug resistance by known or unannotated bacterial virulence factors as well as mammalian cell signaling *** widespread use of antibiotics and the slow development of effective antimicrobials present daunting challenges and necessitate new theoretical and practical platforms to screen and develop mechanism-tested novel drugs to treat intractable infections,especially those caused by multi-drug resistance *** from has advancing in research tools and technology,dissecting this pathogen’s feature has entered into molecular and mechanistic details as well as dynamic and holistic ***,we comprehensively review the progress and discuss the current status of *** biophysical traits,behaviors,virulence factors,invasive regulators,and host defense patterns against its infection,which point out new directions for future investigation and add to

关键词： pathogenesis resistance interaction

Fabrication and application prospects of Pr-Fe-B/Alnico nanocomposite alloys

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Rare Earths 2024年第9期42卷 1717-1723,I0003页

作者： Hui liang Sajjad Ur Rehman Ruibiao Zhang Yongqiang Deng haihua Liu Munan Yang National Rare Earth Functional Materials Innovation Center College of Rare EarthsJiangxi University of Science and TechnologyGanzhou341000China Zhejiang Tiantong Electronic Information Materials Research Institute Co. Ltd.Haining314400China

The potentials of rare earth-based nanocomposite alloys have never been realized due to strict microstructural *** to the easy demagnetization it is challenging to increase the soft magnetic phase *** avoid the easy demagnetization,Pr-Fe-B/Alnico magnets were fabricated and reported in this *** content of the Alnico phase is increased from 0 to 25 wt%,while the content of Pr element is reduced to below the sub-stoichiometry of the 2:14:1 main *** maximum magnetic energy product,which is the figure-of-merit for permanent magnets,is increased from 122 kJ/m^(3) for the standard alloy to 146 kJ/m^(3) for the alloy with 15 wt% Alnico which shows a significant improvement considering the fact that the Curie point of the magnet is also increased by~66 *** special microstructure contains distinctly and heterogeneously distributed 2:14:1 and Alnico *** dimensions of neither the 2:14:1 nor the Alnico phases meet the dimensional requirements of the nanocomposite magnets,but still the smooth demagnetization curves are noted for the *** behavior of effective anisotropy,the performance of the magnets in applied magnetic field and the magnetic interactions among the various constituent grains were quantitatively studied by reversible susceptibility,irreversible susceptibility and re coil loop *** study may provide some guiding principles for the development of nanocomposite magnetic alloys with excellent magnetic properties by using much less RE elements.

关键词： Composite alloys High performance magnets Magnetic properties Alnico alloys Rare earth magnets

A preliminary analysis of arcuate structures-relationship of the island arc and deep-sea trench to the dip angle of Benioff zone

在线全文

学校读者我要写书评

暂无评论

Acta Oceanologica Sinica 1989年第1期8卷 125-136页

作者： Wu Lun, liang haihua, Ren Fuhu and Li Maosong The Department of Geography, Peking University, Beijing, China The Department of Geology, Peking University, Beijing, China Dept of Geography Peking Univ. Beijing China China

The origin of arcuate islands and deep-sea trenches has been studied for a long time and various interpretations have been proposed. In this paper, some analytical models are put forward from a geometrical viewpoint and then the theoretical dip angles of the underthrusting slabs of circum-Pacific island arcs are computed and compared with those of the Benioff zone. As a result, it is found that the dip angle of the underthrusting slab is one of the main factors determining the curvature of the arcuate structure. The authors consider that this result may contribute to the plate theory.

关键词： A preliminary analysis of arcuate structures-relationship of the island arc and deep-sea trench to the dip angle of Benioff zone deep

Differential Tectonic Stress Pattern Between the Deep and Shallow Crust in North China and Its Possible Genesis

在线全文

学校读者我要写书评

暂无评论

Earthquake Research in China 2000年第3期14卷 63-71页

作者： liang haihua Liu Shuwen Hou Jianjun Chang Zufeng Department of Geology Peking University Beijing 100871 China

This paper approaches the neotectonic stress field based on the data of foeal mechanismsolution,ground stress measurement,tectonic mechanical analysis and geodetic surveying,and finds out that the orientations of the maximum principal comproessive sterss patterns arequite discordant with different methods and the stress patterns are widely differnt betweenthose in the shallow and deep part of the crust in North *** on the analysis ofabove-mentioned data,we established a duplex model by considering the diversities of theStress patterns in 3-dimentional spaces,the boundary conditions and the lithospheric media,and made an inverse calculation by using the finite element *** calculated results fitwell with the reality in North China,*** stress patterns in lower crust which is below thedetachment interface at the deptp of 10 km from ground surface are relatively consistent withnearly horizontal state and NE-ENE trending of the maximum principal compressive stressaxes,whereas the stress

关键词： Duplex model of tectonic stress Detachment interface North China block

The effect of pmpR on the type Ⅲ secretion system in Pseudomonas aeruginosa

在线全文

学校读者我要写书评

暂无评论

Chinese Science Bulletin 2012年第19期57卷 2413-2418页

作者： liang haihua KONG WeiNa SHEN Tuo DUAN JiaLi DUAN KangMin Key Laboratory of Resources Biology and Biotechnology in Western China Ministry of EducationFaculty of Life SciencesNorthwest UniversityXi'anShaanxi 710069China

The type III secretion system(T3SS) plays important roles in Pseudomonas aeruginosa ***,we reported that the uncharacterized protein PmpR could regulate pqsR,an important regulator in the quorum-sensing system,by directly binding to its promoter *** the T3SS is controlled by the quorum-sensing system,here,we investigated the relationship between PmpR and the *** data showed that expression of the T3SS genes exoS,exoY,exoT,and exsD was dramatically increased in a pmpR-deletion mutant compared with that in the wild-type *** strain *** from DNA mobility assays indicated that PmpR affects the T3SS *** is unlikely that PmpR controls the T3SS via the Pseudomonas quinolone signal(PQS) because the PQS negatively regulates the T3SS,while pmpR negatively regulates the *** effect of PmpR on the T3SS seems to be independent of the PQS;further investigation is required to uncover the underlying regulatory pathways.

关键词：分泌系统绿脓杆菌类型缺失突变体传感系统感应系统假单胞菌数据表

Targeting complement hyperactivation:a novel therapeutic approach for severe pneumonia induced by influenza virus/staphylococcus aureus coinfection

在线全文

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2024年第1期9卷 51-54页

作者： Leili Jia haihua Luo Lizhong Li Mingyao Wang Jiangfeng Liu Yuan liang Shan Li Yong Jiang Juntao Yang Hongbin Song Institute for Disease Control and Prevention of PLA BeijingChina Guangdong Provincial Key Laboratory of Proteomics State Key Laboratory of Organ Failure ResearchSchool of Basic Medical SciencesSouthern Medical UniversityGuangzhou 510515China State Key Laboratory of Common Mechanism Research for Major Diseases Institute of Basic Medical SciencesChinese Academy of Medical Science and Peking Union Medical College100005 BeijingChina

Dear Editor,Infections by the influenza virus are a significant and widespread global health threat,as these infections have an annual death toll ranging from 290,000 to 650,000.1 A significant proportion of these fatalities are attributed to secondary bacterial pneumonia,a severe complication commonly caused by ubiquitous respiratory pathogens such as Staphylococcus aureus(***).2 Of particular concern is the increased morbidity and mortality rates in individuals infected simultaneously with influenza virus and methicillin-resistant ***(MRSA).3 The concurrent presence of bacteria and influenza virus usually causes acute respiratory distress syndrome(ARDS),which is associated with acute lung injury(ALI),severe lung tissue edema,and widespread ***,determining the complex mechanisms underlying the synergistic interplay will require further investigation with a suitable coinfection mouse *** our previous study,we utilized different sequential coinfections at various time points to model influenza A virus and MRSA coinfection.

关键词： influenza pneumonia lung