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A cross-sectional study on predictors of patients'' tinnitus severity

世界耳鼻咽喉头颈外科杂志英文版 2024年第03期10卷 173-179页

作者： Li Teng-Fei Cha Xu-Dong Wang Tian-Yu liang cai-quan Li Feng-Zhen Wang Sheng-Lei Peng Hu Ren Wen-Wen Deng Yue Liu Huan-Hai Department of Otorhinolaryngology Changzheng Hospital Naval Medical University (Second Military Medical University) Shanghai China

Objective: To identify factors that influence the severity of tinnitus via a hierarchical multiple linear regression ***: The study was a retrospective cross-sectional analysis. The study included 331 patients experiencing tinnitus as their primary concern, who visited Shanghai Changzheng Hospital of the Navy Medical University between 2019 and 2021. Data on general health status and disease characteristics were collected from all patients. With their consent, participants underwent audiological evaluatons and completed questionnaires to analyze the characteristics of their tinnitus and the factors influencing its ***: The correlation analysis showed a positive relationship between tinnitus frequency, tinnitus loudness, SAS scores, and PSQI scores with THI scores (P < 0.05) among nine examined variables (gender, handedness, employment status, age, BMI, tinnitus frequency, tinnitus loudness, SAS scores, and PSQI scores). The variables that were extracted from the multiple regression were; for the constant;β =-51.797,t = -4.484,P < 0.001, variable is significant; for the tinnitus loudness;β= 0.161,t = 2.604,P < 0.05, variable is significant; for the tinnitus frequency;β = 0.000,t= 1.269,P= 0.206, variable is not significant; for the SAS scores;β= 1.310,t = 7.685,P < 0.001, variable is significant; for the PSQI scores;β= 1.680,t = 5.433,P < 0.001, variable is significant. Therefore, the most accurate model for predicting severity in tinnitus patients is a linear combination of the constant, tinnitus loudness, SAS scores, and PSQI scores,Y (Tinnitus severity) =β0+β1(Tinnitus loudness) + β2(SAS scores) +β3(PSQI scores).β0,β1,β2, andβ3 are -51.797, 0.161, 1.310 and 1.680, ***: Tinnitus severity is positively associated with loudness, anxiety levels, and sleep quality. To effectively manage tinnitus in patients, it is essential to promptly identify and address these accompanying factors and related symptoms.

关键词： hierarchical multiple linear regression tinnitus

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Weakly-supervised instance co-segmentation via tensor-based salient co-peak search

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Frontiers of Computer Science 2024年第2期18卷 83-92页

作者： Wuxiu quan Yu HU Tingting DAN Junyu LI Yue ZHANG Hongmin cai School of Computer Science Guangdong Polytechnic Normal UniversityGuangzhou 510665China School of Computer Science and Engineering South China University of TechnologyGuangzhou 510006China

Instance co-segmentation aims to segment the co-occurrent instances among two *** task heavily relies on instance-related cues provided by co-peaks,which are generally estimated by exhaustively exploiting all paired candidates in point-to-point ***,such patterns could yield a high number of false-positive co-peaks,resulting in over-segmentation whenever there are mutual *** tackle with this issue,this paper proposes an instance co-segmentation method via tensor-based salient co-peak search(TSCPS-ICS).The proposed method explores high-order correlations via triple-to-triple matching among feature maps to find reliable co-peaks with the help of co-saliency *** proposed method is shown to capture more accurate intra-peaks and inter-peaks among feature maps,reducing the false-positive rate of co-peak *** having accurate co-peaks,one can efficiently infer responses of the targeted *** on four benchmark datasets validate the superior performance of the proposed method.

关键词： weakly-supervised co-segmentation co-peak tensormatching deep network instance segmentation

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Particle residence time distribution and axial dispersion coefficient in a pressurized circulating fluidized bed by using multiphase particle-in-cell simulation

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Chinese Journal of Chemical Engineering 2024年第5期69卷 167-176页

作者： Jinnan Guo Daoyin Liu Jiliang Ma cai liang Xiaoping Chen Key Laboratory of Energy Thermal Conversion and Control of Ministry of Education Southeast UniversityNanjing 210096China

The particle residence time distribution(RTD)and axial dispersion coefficient are key parameters for the design and operation of a pressurized circulating fluidized bed(PCFB).In this study,the effects of pressure(0.1-0.6 MPa),fluidizing gas velocity(2-7 m·s^(-1)),and solid circulation rate(10-90 kg·m^(-2)·s^(-1))on particle RTD and axial dispersion coefficient in a PCFB are numerically investigated based on the multiphase particle-in-cell(MP-PIC)*** details of the gas-solid flow behaviors of PCFB are *** on the gas-solid flow pattern,the particles tend to move more orderly under elevated *** an increase in either fluidizing gas velocity or solid circulation rate,the mean residence time of particles decreases while the axial dispersion coefficient *** an increase in pressure,the core-annulus flow is strengthened,which leads to a wider shape of the particle RTD curve and a larger mean particle residence *** back-mixing of particles increases with increasing pressure,resulting in an increase in the axial dispersion coefficient.

关键词： Pressurized circulating fluidized bed MP-PIC method Residence time distribution Axial dispersion coefficient

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Complete kinetic model for esterification reaction of lauric acid with glycerol to synthesize glycerol monolaurate

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Chinese Journal of Chemical Engineering 2024年第6期70卷 211-221页

作者： Han-Qiao Hu Yue Zhang Ming Fan Yong cai Guang-Wen Chu liang-liang Zhang Research Center of the Ministry of Education for High Gravity Engineering and Technology Beijing University of Chemical TechnologyBeijing 100029China State Key Laboratory of Organic-Inorganic Composites Beijing University of Chemical TechnologyBeijing 100029China Petrochemical Research Institute China National Petroleum CorporationBeijing 102206China

Glycerol monolaurate(GML)is a widely used industrial chemical with excellent emulsification and antibacterial *** direct esterification of glycerol with lauric acid is the main method to synthesize *** this work,the kinetic process of direct esterification was systematically studied using p-toluenesulfonic acid as catalyst.A complete kinetic model of consecutive esterification reaction has been established,and the kinetic equation of acid catalysis was *** isomerization reactions of GML and glycerol dilaurate were *** was found that the reaction was an equilibrium reaction and the reaction rate was faster than the esterification *** kinetic equations of the consecutive esterification reaction were obtained by experiments as k_(1)=(276+92261Xcat)exp(-37720/RT)and k_(2)=(80+4413Xcat)exp(-32240/RT).The kinetic results are beneficial to the optimization of operating conditions and reactor design in GML production process.

关键词： Glycerol monolaurate p-Toluenesulfonic acid Esterification Kinetics Mass transfer

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Narrowband blue emitter based on fused nitrogen/carbonyl combination with external quantum efficiency approaching 30%

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Science China Chemistry 2024年第1期67卷 351-359页

作者： Long Chen Jia-Heng cai You-Jun Yu Yang-Kun Qu Sheng-Yi Yang Sheng-Nan Zou Rui-Hong Liu Dong-Ying Zhou liang-Sheng Liao Zuo-quan Jiang Institute of Functional Nano&Soft Materials(FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials&DevicesSoochow UniversitySuzhou 215123China Macao Institute of Materials Science and Engineering Macao University of Science and TechnologyMacao 999078China

Multi-resonance thermally activated delayed fluorescence(MR-TADF)emitters can enable narrowband emission with high color purity and electroluminescence ***/carbonyl(N/C=O)system is receiving increasing attention while the nitrogen/boron(N/B)system has been widely *** decoration is an effective approach for N/B type MR-TADF system but always leads to broadening and red-shifting of the emission band in N/C=O MR-TADF *** attribute these unfavorable phenomena to the formation of intramolecular charge transfer between the MR-core and peripheral *** address this issue,we have developed a new strategy by decorating DMQAO(a fused N/C=O MR-core)with a triazine acceptor and a neutral terphenyl group to construct MTDMQAO and MBDMQAO,*** introduction of the triazine acceptor not only realizes efficient narrowband emission in MTDMQAO,but also accelerates the reverse intersystem crossing process through enhanced spin-orbital *** a result,MTDMQAO exhibits a significantly higher external quantum efficiency of 29.4%compared to the referent emitters,validating the rationality of our derivation *** study highlights the potential of the N/C=O system for MR-TADF emitters and provides important insights for understanding the difference between N/B and N/C=O systems.

关键词： carbonyl group narrowband acceptor decoration thermally activated delayed fluorescence OLEDs

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Interplay between microglia and environmental risk factors in Alzheimer's disease

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Neural Regeneration Research 2024年第8期19卷 1718-1727页

作者： Miaoping Zhang Chunmei liang Xiongjin Chen Yujie cai Lili Cui Guangdong Key Laboratory of Age-Related Cardiac and Cerebral Diseases Affiliated Hospital of Guangdong Medical UniversityZhanjiangGuangdong ProvinceChina

Alzheimer s disease,among the most common neurodegenerative disorders,is chara cterized by progressive cognitive *** present,the Alzheimer’s disease main risk remains genetic ris ks,but major environmental fa ctors are increasingly shown to impact Alzheimer’s disease development and ***,the most important brain immune cells,play a central role in Alzheimer’s disease pathogenesis and are considered environmental and lifestyle"sensors."Factors like environmental pollution and modern lifestyles(e.g.,chronic stress,poor dietary habits,sleep,and circadian rhythm disorde rs)can cause neuroinflammato ry responses that lead to cognitive impairment via microglial functioning and phenotypic ***,the specific mechanisms underlying interactions among these facto rs and microglia in Alzheimer’s disease are ***,we:discuss the biological effects of air pollution,chronic stress,gut micro biota,sleep patterns,physical exercise,cigarette smoking,and caffeine consumption on microglia;consider how unhealthy lifestyle factors influence individual susceptibility to Alzheimer’s disease;and present the neuroprotective effects of a healthy *** intervening and controlling these environmental risk fa ctors at an early Alzheimer’s disease stage,understanding the role of microglia in Alzheimer’s disease development,and to rgeting strategies to to rget microglia,co uld be essential to future Alzheimer’s disease treatments.

关键词： Alzheimer’s disease chronic stress environmental factor gut microbiota microglia particulate matter with diameter<2.5μm

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Preparation and characterization of pH-responsive metal-polyphenol structure coated nanoparticles

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Food Science and Human Wellness 2024年第3期13卷 1303-1310页

作者： Qile Xia Yan liang Ailing Cao Yan Cao Luyun cai Key Laboratory of Post-Harvest Handling of Fruits Food Science InstituteZhejiang Academy of Agricultural SciencesHangzhou 310021China Ningbo Research Institute College of Biosystems Engineering and Food ScienceZhejiang UniversityNingbo 315100China School of Biological and Chemical Engineering Zhejiang Engineering Research Center for Intelligent Marine Ranch EquipmentNingboTech UniversityNingbo 315100China College of Food Science and Engineering Bohai UniversityJinzhou 121013China Hangzhou Customs District Hangzhou 310007China

In this paper,tannic acid(TA)and Fe~(3+)were added to form a layer of metal-polyphenol network structure on the surface of the nanoparticles which were fabricated by zein and carbon quantum dots(CQDs)encapsulating phlorotannins(PTN).pH-Responsive nanoparticles were prepared successfully(zein-PTN-CQDs-Fe-~Ⅲ).Further,the formation of composite nanoparticles was confirmed by a series of characterization *** zeta-potential and Fourier transform infrared spectroscopy data proved that electrostatic interaction and hydrogen bonding are dominant forces to form *** encapsulation efficiency(EE)revealed that metal-polyphenol network structure could improve the EE of *** analysis and differential scanning calorimetry experiment indicated the thermal stability of zein-PTN-CQDs-Fe~Ⅲnanoparticles increased because of metal-polyphenol network *** pH-responsive nanoparticles greatly increased the release rate of active substances and achieved targeted release.

关键词： Metal Phlorotannins Nanoparticles pH-Responsive Characterization

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Slow magnetic relaxation and photoluminescence behaviors of dilanthanide complexes bearing N_(8)O_(2)donor macrocyclic ligand

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Journal of Rare Earths 2024年第7期42卷 1298-1303,I0004页

作者： Pei-Yu Liao Yu-quan Qi Zhen Li Jian-Hua Jia Ming-liang Tong Key Laboratory of Bioinorganic and Synthetic Chemistry of Ministry of Education School of ChemistrySun Yat-Sen UniversityGuangzhou510006China

On account of the complicated magnetic exchange interactions between lanthanide ions,binuclear lanthanide complexes have broad application prospect in the field of single-molecule ***,it is necessary to develop reasonable bridging ligands to manipulate the directional assembly of binuclear lanthanide ***,we selected the macrocyclic ligand L^(N_(8)O_(2))to build up two new dilanthanide complexes[Ln_(2)(LN_(8)O_(2))(OpyO)_(2)(H_(2)O)2](NO_(3))_(2)(1-Ln,Ln=Dy,Tb;LN_(8)O_(2)=hexamethyl-tetraaza-dioxe-dipyrazolacycloicosaphane-2,9,12,19-tetraene;OpyOH=2-pyridinol-1-oxide).Dynamic magnetic studies show that 1-Dy exhibits slow relaxation behavior under a 1 kOe applied *** fitting analysis of relaxation times gives the effective energy barrier of 38.2 cm^(−1),and reveals that the slow magnetic relaxation behavior is dominated by the Orbach and Raman ***-resolution luminescence emission spectrum indicates the energy gap of 36.8 cm^(−1)between the ground state and the first excited state,consistent with the magnetic measurement results.1-Tb exhibits brilliant characteristic green light emission under UV light *** absolute quantum yield of 1-Tb is 44.8%,and its first-order fitted decay lifetime is 779.21μs at room *** study provides the way for directional construction of high-performance molecular materials with magnetic and optical dual-function.

关键词： Dilanthanide complexes Single-molecule magnets Macrocyclic ligand Photoluminescence behavior Rare earths

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Pt nanoclusters modified porous g-C_(3)N_(4)nanosheets to significantly enhance hydrogen production by photocatalytic water reforming of methanol

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Chinese Journal of Chemical Engineering 2024年第2期66卷 40-50页

作者： Yi-Fei liang Jin-Rong Lu Shang-Kun Tian Wen-quan Cui Li Liu Hebei Provincial Key Laboratory of Environmental Photocatalytic and Electrocatalytic Materials College of Chemical EngineeringNorth China University of Science and TechnologyTangshan 063210China

For the use of green hydrogen energy,it is crucial to have efficient photocatalytic activity for hydrogen generation by water reforming of methanol under mild *** attention has been paid to gC_(3)N_(4)as a promising photocatalyst for the generation of *** improve the separation of photogenerated charge,porous nanosheet g-C_(3)N_(4)was modified with Pt nanoclusters(Pt/g-C_(3)N_(4))through impregnation and following photo-induced *** catalyst showed excellent photocatalytic activity of water reforming of methanol fo r hydrogen production with a 17.12 mmol·g^(-1)·h^(-1)rate at room temperature,which was 311 times higher than that of the unmodified g-C_(3)N_(4).The strong interactions of Pt-N in Pt/g-C_(3)N_(4)constructed effective electron transfer channels to promote the separation of photogenerated electrons and holes *** addition,in-situ infrared spectroscopy was used to investigate the intermediates of the hydrogen production reaction,which proved that methanol and water eventually turn into H_(2)and CO_(2)via formaldehyde and *** study provides insights for understanding the photocatalytic hydrogen production in the water reforming of methanol.

关键词： Water reforming of methanol Photocatalysis g-C_(3)N_(4) Pt nanoclusters Hydrogen production

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Roles of nanoparticles in arsenic mobility and microbial community composition in arsenic-enriched soils

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Journal of Environmental Sciences 2024年第4期138卷 301-311页

作者： Ting Luo Qining Zheng Jie Yu Weihao liang Yan Sun Guixiang quan Feng Zhou School of Environmental Science and Engineering Yancheng Institute of TechnologyYancheng 224051China Jiangsu Provincial Key Laboratory of Coastal Ecology and Pollution Control Yancheng 224051China School ofEnvironment and Civil Engineering Jiangnan UniversityWuxi 214122China

Environmental effects of nano remediation engineering of arsenic(As)pollution need to be *** this study,the roles of Fe_(2)O_(3)and TiO_(2)nanoparticles(NPs)on the microbial mediated As mobilization from As contaminated soil were *** addition of Fe_(2)O_(3)and TiO_(2)NPs restrained As(V)release,and stimulated As(Ⅲ)***(V)concentration decreased by 94% and 93% after Fe_(2)O_(3)addition,and decreased by 89% and 45% after Ti O_(2)addition compared to the Biotic and Biotic+Acetate(amended with sodium acetate)controls,*** maximum values of As(Ⅲ)were 20.5 and 27.1μg/L at 48 d after Fe_(2)O_(3)and TiO_(2)NPs addition,respectively,and were higher than that in Biotic+Acetate control(12.9μg/L).The released As co-precipitated with Fe in soils in the presence of Fe_(2)O_(3)NPs,but adsorbed on TiO_(2)NPs in the presence of TiO_(2)***,the addition of NPs amended with sodium acetate as the electron donor clearly promoted As(V)reduction induced by *** NPs addition changed the relative abundance of soil bacterial community,while Proteobacteria(42.8%-70.4%),Planctomycetes(2.6%-14.3%),and Firmicutes(3.5%-25.4%)were the dominant microorganisms in *** potential As/Fe reducing bacteria were related to Pseudomonas,Geobacter,Desulfuromonas,and *** addition of Fe_(2)O_(3)and TiO_(2)NPs induced to the decrease of arr A *** results indicated that the addition of NPs had a negative impact on soil microbial population in a long *** findings offer a relatively comprehensive assessment of Fe_(2)O_(3)and TiO_(2)NPs effects on As mobilization and soil bacterial communities.

关键词： Fe_(2)O_(3)and TiO_(2)nanoparticles Arsenic reduction Mobilization Functional gene Microbial community

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