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HLA抗原与银屑病

中华皮肤科杂志 1981年第4期14卷 191-194页

作者：宋芳吉陈跃华刘子勇李惠刚徐沈育苏霄汉杨次颖刘忠环董国权中国医科大学附属第一医院免疫室皮肤科中国医科大学附属第一医院

自从1972年 Russell 及 White 等报道了 HLA—B17与银屑病明显相关后,Krain等相继进行了 HLA 与银屑病相关的研究,进一步指出银屑病患者 HLA—B13、HLA—B17的抗原频率明显增高。此外

关键词：抗原银屑病

Tumor microenvironment-responsive MnSiO_(3)-Pt@BSA-Ce6 nanoplatform for synergistic catalysis-enhanced sonodynamic and chemodynamic cancer therapy

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Chinese Chemical Letters 2022年第6期33卷 2959-2964页

作者： Fan Jiang Chunzheng Yang Binbin Ding Shuang Liang Yajie Zhao ziyong Cheng Min liu Bengang Xing Ping’an Ma Jun Lin State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China Department of Periodontology Stomatological HospitalJilin UniversityChangchun 130021China School of Physical&Mathematical Sciences Nanyang Technological UniversitySingapore 639798Singapore

Compared with traditional photodynamic therapy(PDT),ultrasound(US)triggered sonodynamic therapy(SDT)has a wide application prospect in tumor therapy because of its deeper penetration ***,a novel MnSiO_(3)-Pt(MP)nanocomposite composed of Mn Si O_(3)nanosphere and noble metallic Pt was successfully *** modification with bovine serum albumin(BSA)and chlorine e6(Ce6),the multifunctional nanoplatform Mn SiO_(3)-Pt@BSA-Ce6(MPBC)realized the magnetic resonance imaging(MRI)-guided synergetic SDT/chemodynamic therapy(CDT).In this nanoplatform,sonosensitizer Ce6 can generate singlet oxygen(^(1)O_(2))to kill cancer cells under US ***,the loaded Pt has the ability to catalyze the decomposition of overexpressed hydrogen peroxide(H_(2)O_(2))in tumor microenvironment(TME)to produce oxygen(O_(2)),which can conquer tumor hypoxia and promote the SDT-induced^(1)O_(2)*** addition,MP can degrade in mildly acidic and reductive TME,causing the release of Mn^(2+).The released Mn^(2+) not only can be used for MRI,but also can generate hydroxyl radical(^·OH)for CDT by Fenton-like *** multifunctional nanoplatform MPBC has high biological safety and good anticancer effect,which displays the great latent capacity in biological application.

关键词： Sonodynamic therapy Chemodynamic therapy Artificial enzyme Oxygen generation Synergetic therapy

Systemically comparing host immunity between survived and deceased COVID-19 patients

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Cellular & Molecular Immunology 2020年第8期17卷 875-877页

作者： Feng Wang Hongyan Hou Yin Yao Shiji Wu Min Huang Xiao Ran Hongmin Zhou Zheng liu ziyong Sun Department of Laboratory Medicine Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina Department of Otolaryngology-Head and Neck Surgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina Department of Emergency Medicine Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina Department of Cardiothoracic and Vascular Surgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina

Novel severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has caused the disastrous pandemic of Coronavirus Disease-2019(COVID-19).1,2,3 Although the epidemiological,clinical,and immunological characteristics of COVID-19 have been reported,4,5,6 the kinetics of immune responses and their association with clinical outcomes remain poorly ***,we summarize the characteristics of cellular immune responses in a total of 157 COVID-19 patients enrolled in Tongji Hospital between February and March 2020 and compare the properties between 95 survived and 62 deceased patients with different onset *** demographic and clinical characteristics of these patients are shown in Supplementary Table *** significant difference in age,gender,clinical symptoms,and imaging features was recorded between survived and deceased patients.

关键词： patients immunity clinical

Research on the Three-phase Photovoltaic Grid-connected Control Strategy

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Energy and Power Engineering 2013年第4期5卷 31-35页

作者： Yukai liu Zhijian Hu ziyong Zhang Jianglei Suo Kaibin Liang School of Electrical Engineering Wuhan University Wuhan China

This paper mainly studies scheduling type photovoltaic generation system, and establishes a three-phase photovoltaic grid-connected model in Matlab/Simulink, which uses the MPPT control that can make full use of the solar energy. At the same time, energy storage device is added. The inverter of the energy storage device adopts V/f control. In the running state of the islanding because of a certain power failure, it can maintain a constant voltage and frequency. The simulation shows that as the output of the photovoltaic power increases, harmonic rate decreases under the same conditions, and the energy storage device can increase the stability of photovoltaic grid and reduce harmonic contents. So it’s very necessary to add energy storage device in the photovoltaic system.

关键词： Photovoltaic Grid Energy Storage Device PQ Control V/f Control Harmonic Rate

从地区性市场走向区域性市场——基于五大城市群市场分割的测算

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经济问题探索 2021年第1期 124-135页

作者：刘昊祝志勇西南大学经济管理学院重庆400715 西南大学经济研究中心重庆400715

新冠疫情在全球范围内的蔓延进一步凸显了建立一个国内统一市场的重要性。通过对2001-2018年五大城市群内部与城市群之间市场分割水平的测度和比较,发现城市群内部市场分割水平逐渐下降,不同行政区划所带来的边界效应逐渐减弱,但城市群... 详细信息

新冠疫情在全球范围内的蔓延进一步凸显了建立一个国内统一市场的重要性。通过对2001-2018年五大城市群内部与城市群之间市场分割水平的测度和比较,发现城市群内部市场分割水平逐渐下降,不同行政区划所带来的边界效应逐渐减弱,但城市群之间市场分割水平较高,提出我国产品市场一体化正从以省界为界限的地区性市场向以城市群为界限的区域性市场演进。对各城市群内部市场分割影响因素的实证分析结果表明,政府干预和地区市场规模的提升是各城市群市场一体化水平提升的主要动力,对外开放对市场一体化的助推作用不明显,以上因素对五大城市群市场分割的影响也存在显著差异。

关键词：市场分割行政区划城市群

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复杂环境下隧道施工涌水致灾机理及影响分析

铁道科学与工程学报 2024年第12期21卷 5140-5150页

作者：蔡子勇乔世范刘屹颀中湘海外建设发展有限公司湖南长沙410004 中南大学土木工程学院湖南长沙410075

涌水是隧道施工常见的地质灾害之一,严重威胁隧道施工安全。以下穿水库及穿越断层构造带隧道涌水案例为背景,从地质特征、围岩揭露、地质雷达探测及涌水形态多维度出发,系统分析隧道涌水致灾原因,以此建立隧道涌水分析模型。基于极限平... 详细信息

涌水是隧道施工常见的地质灾害之一,严重威胁隧道施工安全。以下穿水库及穿越断层构造带隧道涌水案例为背景,从地质特征、围岩揭露、地质雷达探测及涌水形态多维度出发,系统分析隧道涌水致灾原因,以此建立隧道涌水分析模型。基于极限平衡理论及渗流理论,推导隧道涌水安全临界厚度计算公式,提出隧道涌水稳定性判据,并基于单因素变量法及灰色关联法,探讨隧道涌水影响机制。研究结果表明:1)此次隧道涌水实质是隧道拱部潜伏着规模不大的含水溶腔,隧道开挖引起围岩应力重分布及地下水能量释放,在动水压力及渗透冲刷作用下,加之开挖扰动对围岩渗透系数改变及渗流影响,促使裂隙水运动诱发裂隙通道扩展贯通形成的小规模管道型涌水渐进性渗透破坏;2)提出了该隧道涌水致灾形成的3个基本要素:地表集水、地质构造及渗透水压;3)隧道临界安全厚度随着含水溶腔水压及裂隙通道直径的增加而增大,随着黏聚力的增大而减少,随着内摩擦角的增大其影响甚小,得到其影响因素敏感性先后排序为:裂隙通道直径>溶腔水位高度>填充介质黏聚力>内摩擦角,裂隙通道直径对隧道安全稳定影响最大。4)研究成果对理解隧道涌水机理及为类似工程涌水安全防控提供参考。

关键词：隧道施工断层构造涌水临界安全厚度灰色关联法

Wide-Area Delay-Dependent Adaptive Supervisory Control of Multi-machine Power System Based on Improve Free Weighting Matrix Approach

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Energy and Power Engineering 2013年第4期5卷 435-441页

作者： ziyong Zhang Zhijian Hu Yukai liu Yang Gao He Wang Jianglei Suo Jiangsu Suzhou Power Supply Company STATE GRID Corporation of China Suzhou China School of Electrical Engineering Wuhan University Wuhan China School of Electrical Engineering Wuhan University Wuhan China.

The paper demonstrates the possibility to enhance the damping of inter-area oscillations using Wide Area Measurement (WAM) based adaptive supervisory controller (ASC) which considers the wide-area signal transmission delays. The paper uses an LMI-based iterative nonlinear optimization algorithm to establish a method of designing state-feedback controllers for power systems with a time-varying delay. This method is based on the delay-dependent stabilization conditions obtained by the improved free weighting matrix (IFWM) approach. In the stabilization conditions, the upper bound of feedback signal’s transmission delays is taken into consideration. Combining theoriesof state feedback control and state observer, the ASC is designed and time-delay output feedback robust controller is realized for power system. The ASC uses the input information from Phase Measurement Units (PMUs) in the system and dispatches supplementary control signals to the available local controllers. The design of the ASC is explained in detail and its performance validated by time domain simulations on a New England test power system (NETPS).

关键词： Adaptive Supervisory Controller (ASC) Delay-dependent Damping Control Power Oscillation IFWM LMI Free Weighting Matrix Approach Time-varying Delay WAMS

THE　EFFECTIVE　CHARGE　EFFECT　OF　PARTIALLY　STRIPPED　Oq+ION　IN　COLLISION　WITH　HEliuM

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原子与分子物理学报 1997年第1期 16-21页

作者： Cai Xiaohon a,b liu Zhaoyuan b Chen Ximeng b Shen ziyong b Ma Xinwen a liu Huiping a Hou Mingdong a aInstitute of Modern Physics, Academia Sinica, P.O. Box 31, Lanzhou 730000 P.R.China bDepartment of Modern Physics, Lanz

ＡＢＳＴＲＡＣＴＴｏｉｎｖｅｓｔｉｇａｔｅｔｈｅｅｆｅｃｔｉｖｅｃｈａｒｇｅｅｆｅｃｔｉｎｐａｒｔｉａｌｙｓｔｒｉｐｐｅｄｉｏｎｈｅｌｉｕｍｃｏｌｉｓｉｏｎｓｎｅｗｍｅａｓｕｒｅｍｅｎｔｓｏｆｔｈｅｄｏｕｂｌｅａｎ... 详细信息

ＡＢＳＴＲＡＣＴＴｏｉｎｖｅｓｔｉｇａｔｅｔｈｅｅｆｅｃｔｉｖｅｃｈａｒｇｅｅｆｅｃｔｉｎｐａｒｔｉａｌｙｓｔｒｉｐｐｅｄｉｏｎｈｅｌｉｕｍｃｏｌｉｓｉｏｎｓｎｅｗｍｅａｓｕｒｅｍｅｎｔｓｏｆｔｈｅｄｏｕｂｌｅａｎｄｓｉｎｇｌｅｉｏｎｉｚａｔｉｏｎｃｒｏｓｓｅｃｔｉｏｎｒａｔｉｏｓｏｆｈｅｌｉｕｍｂｙｐａｒｔｉａｌｙｓｔｒｉｐｐｅｄｏｘｙｇｅｎｉｏｎｓｈａｖｅｂｅｅｎｍａｄｅｆｏｒｐｒｏｊｅｃｔｉｌｅｃｈａｒｇｅｓｔａｔｅｓｒａｎｇｉｎｇｆｏｒｍ＋１ｔｏ＋４，ｉｍｐａｃｔｅｎｅｒｇｉｅｓｆｒｏｍ１．５ＭｅＶｔｏ７．５ＭｅＶ．Ｉｔｉｓｆｏｕｎｄｔｈａｔｔｈｅｅｆｅｃｔｉｖｅｃｈａｒｇｅｑｅｆｆｉｎｃｒｅａｓｅｓａｓｔｈｅｉｍｐｉｎｇｉｎｇｅｎｅｒｇｙｉｎｃｒｅａｓｅｓａｎｄｑｅｆｆｓｈｏｗｓａｍｏｄｅｓｔｄｅｐｅｎｄｅｎｃｅｕｐｏｎｔｈｅｐｒｏｊｅｃｔｉｌｅｃｈａｒｇｅｓｔａｔｅｉｎｔｈｅｐｒｅｓｅｎｔｅｎｅｒｇｙｒａｎｇｅ．Ｔｈｅｐｒｏｊｅｃｔｉｌｅｃｈａｒｇｅｓｔａｔｅ，ｐｒｏｊｅｃｔｉｌｅａｎｄｔａｒｇｅｔｅｌｅｃｔｒｏｎｉｃｓｔａｔｅｄｅｐｅｎｄｅｎｃｅｓｏｆｔｈｅｅｆｅｃｔｉｖｅｃｈａｒｇｅｅｆｅ

关键词： COLLISION WITH HEliuM EFFECT CHARGE

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水冷壁管受热面失效分析

腐蚀科学与防护技术 1999年第3期11卷 189-192页

作者：刘素娥朱自勇中国科学院金属腐蚀与防护研究所金属腐蚀与防护国家重点实验室

通过电子探针、能谱和Ｘ射线衍射等多种分析技术系统分析某电厂锅炉水冷壁管发生局部腐蚀的原因．结果表明，腐蚀产物中硫含量很高，局部区域超过２０（ｗｔ％），产物主要由铁的氧化物和硫化物组成．水冷壁管受热面腐蚀主要原因是高温... 详细信息

通过电子探针、能谱和Ｘ射线衍射等多种分析技术系统分析某电厂锅炉水冷壁管发生局部腐蚀的原因．结果表明，腐蚀产物中硫含量很高，局部区域超过２０（ｗｔ％），产物主要由铁的氧化物和硫化物组成．水冷壁管受热面腐蚀主要原因是高温硫腐蚀．

关键词：水冷壁管高温硫腐蚀锅炉受热面失效分析