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Prediction of extreme wind velocity at the site of the Runyang Suspension Bridge

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2011年第8期12卷 605-615页

作者： Yang deng You-liang DING Ai-qun li Guang-dong ZHOU Key Laboratory of Concrete and Prestressed Concrete Structures of Ministry of Education Southeast University Nanjing 210096 China

This paper presents a distribution free method for predicting the extreme wind velocity from wind monitoring data at the site of the Runyang Suspension Bridge (RSB), China using the maximum entropy theory. The maximum entropy theory is a rational approach for choosing the most unbiased probability distribution from a small sample, which is consistent with available data and contains a minimum of spurious information. In this paper, the theory is used for estimating a joint probability density function considering the combined action of wind speed and direction based on statistical analysis of wind monitoring data at the site of the RSB. The joint probability distribution model is further used to estimate the extreme wind velocity at the deck level of the RSB. The results of the analysis reveal that the probability density function of the maximum entropy method achieves a result that fits well with the monitoring data. Hypothesis testing shows that the distributions of the wind velocity data collected during the past three years do not obey the Gumbel distribution. Finally, our comparison shows that the wind predictions of the maximum entropy method are higher than that of the Gumbel distribution, but much lower than the design wind speed.

关键词： Extreme wind velocity Maximum entropy theory Probability density function Structural health monitoring(SHM)

A facial strategy to efficiently improve catalytic performance of CoFe_(2)O_(4) to peroxymonosulfate

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Journal of Environmental Sciences 2022年第6期34卷 1-13页

作者： lili Gao Jieqiong deng Tong li Kai Qi Jiandong Zhang qun Yi College of Environmental Science and Engineering Taiyuan University of TechnologyTaiyuan 030024China College of Biomedical Engineering Taiyuan University of TechnologyTaiyuan 030024China

Cobalt iron spinel(CoFe_(2)O_(4)) has been considered as a good heterogeneous catalysis to peroxymonosulfate(PMS) in the degradation of persistent organic pollutants due to its magnetic properties and good chemical stability. However, its catalytic activity needs to be further improved. Here, a facial strategy, “in-situ substitution”, was adopted to modify CoFe_(2)O_(4) to improve its catalytic performance just by suitably increasing the Co/Fe ratio in synthesis process. Compared with CoFe_(2)O_(4), the newly synthesized Co_(1.5)Fe_(1.5)O_(4), could not only significantly improve the degradation efficiency of phenol, from 50.69 to 93.6%, but also exhibited more effective mineralization ability and higher PMS utilization. The activation energy advantage for phenol degradation using Co_(1.5)Fe_(1.5)O_(4)was only 44.2 k J/mol, much lower than that with CoFe_(2)O_(4)(127.3 k J/mol). A series of related representations of CoFe_(2)O_(4) and Co_(1.5)Fe_(1.5)O_(4) were compared to explore the possible reasons for the outstanding catalytic activity of Co_(1.5)Fe_(1.5)O_(4). Results showed that Co_(1.5)Fe_(1.5)O_(4)as well represented spinel crystal as CoFe_(2)O_(4)and the excess cobalt just partially replaced the position of iron without changing the original structure. Co_(1.5)Fe_(1.5)O_(4) had smaller particle size(8.7 nm), larger specific surface area(126.3 m^(2)/g), which was more favorable for exposure of active sites. Apart from the superior physical properties, more importantly, more reactive centers Co(Ⅱ) and surface hydroxyl compounds generated on Co_(1.5)Fe_(1.5)O_(4), which might be the major reason. Furthermore, Co_(1.5)Fe_(1.5)O_(4) behaved good paramagnetism, wide range of pH suitability and strong resistance to salt interference, making it a new prospect in environmental application.

关键词： CoFe_(2)O_(4) Co_(1.5)Fe_(1.5)O_(4) In-situ substitution Peroxymonosulfate(PMS) Advanced oxidation processes(AOPs)

Analysis of the anti-T2DM components in dichloromethane fraction of Schisandra sphenanthera and its mechanism

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Traditional Medicine Research 2025年第1期10卷 27-43页

作者： Shi-Bo Feng Hai-Hui Jiang Hui-li Kang Yi Jiang Hua-Wei Zhang Xiao-Mei Song Yu-Ze li Wen-li Huang Dong-Dong Zhang Chong deng School of Pharmacy Shaanxi University of Chinese MedicineXianyang 712046China School of Pharmacy and Shaanxi Qinling Application Development and Engineering Center of Chinese Herbal Medicine Shaanxi University of Chinese MedicineXianyang 712046China Key Laboratory for Research and Development of“Qin Medicine”of Shaanxi Administration of Traditional Chinese Medicine Xianyang 712046China Shaanxi Key Laboratory of Research and Application of“Taibai Qi Yao” Xianyang 712046China

Background:The type 2 diabetes mellitus(T2DM)pharmacodynamic study of various parts of Schisandra sphenanthera was conducted in the previous stage,and it was found that dichloromethane extracted part(SDP)had a significant hypoglycemic ***,the components of SDP were analyzed,and the specific mechanism of its anti-T2DM was ***:We used a high-fat,high-sugar diet in combination with streptozotocin to induce a T2DM rat model,and the model rats were divided into two groups according to body weight and blood ***,oral glucose tolerance test,fasting blood glucose,low density lipoprotein cholesterol,superoxide dismutase,insulin,glycated hemoglobin,total cholesterol,nonesterified free fatty acids,alanine aminotransferase,high-density lipoprotein cholesterol,aspartate aminotransferase,malondialdehyde,and glutathione peroxidase were measured,organ indices were calculated,and pathological sections of pancreas and liver were *** 16S rRNA V3–V4 region of intestinal flora was sequenced to explore the effect of SDP on biochemical indicators and intestinal *** on the above indicators,the anti-T2DM mechanism of SDP in Schisandra sphenanthera was ***:After six weeks of administration,the biochemical indices of diabetic rats were diminished compared to the control *** SDP could significantly increase the gut microbialα-diversity index,resulting in significant changes in the flora of T2DM rats,with increased richness and diversity,reduced harmful flora,and significantly back-regulated the levels of acetic acid,propionic acid,and butyric ***:SDP can improve the symptoms associated with elevated blood glucose,dyslipidemia,elevated fasting insulin levels,and damaged glucose tolerance in *** against T2DM may be through the control of intestinal flora to normalize and exert anti-diabetic effect;its main active components may be lignans and terpenoids.

关键词： Schisandra sphenanthera T2DM intestinal flora HPLC

Extension and Application of the Wielandt-Hoffman Theorem

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Journal of China University of Mining and Technology 2006年第2期16卷 233-235页

作者： deng qun Editorial Department of Journal China University of Mining ＆ Technology XuzhouJiangsu 221008 China

The Wielandt-Hoffman theorem of the real symmetric matrix is extended into a plural matrix. On the basis of it, a similar theory about the trace of a matrix for the arithmetic mean, geometric mean inequality, Holder i... 详细信息

关键词： Hermitian matrix trace of matrix characteristic value inequality

Stepwise approach for view synthesis

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第8期8卷 1218-1226页

作者： CHAI deng-feng PENG qun-sheng State Key Lab of CAD and CG Zhejiang University Hangzhou 310027 China Institute of Spatial Information Technique Zhejiang University Hangzhou 310027 China

This paper presents some techniques for synthesizing novel view for a virtual viewpoint from two given views cap-tured at different viewpoints to achieve both high quality and high efficiency. The whole process consists of three passes. The first pass recovers depth map. We formulate it as pixel labelling and propose a bisection approach to solve it. It is accomplished in log2n(n is the number of depth levels) steps,each of which involves a single graph cut computation. The second pass detects occluded pixels and reasons about their depth. It fits a foreground depth curve and a background depth curve using depth of nearby fore-ground and background pixels,and then distinguishes foreground and background pixels by minimizing a global energy,which involves only one graph cut computation. The third pass finds for each pixel in the novel view the corresponding pixels in the input views and computes its color. The whole process involves only a small number of graph cut computations,therefore it is efficient. And,visual artifacts in the synthesized view can be removed successfully by correcting depth of the occluded pixels. Experimental results demonstrate that both high quality and high efficiency are achieved by the proposed techniques.

关键词： View synthesis Occlusion Graph cut

Predicting the shrinkage of thermal insulation mortar by probabilistic neural networks

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2010年第3期11卷 212-222页

作者： Yi-qun deng Pei-ming WANG Key Laboratory of Advanced Civil Engineering Materials Ministry of EducationTongji UniversityShanghai 200092China

This study explored the potential of using probabilistic neural networks (PNN) to predict shrinkage of thermal insulation *** results were obtained from the PNN model with the aid of Parzen non-parametric estimator of the probability density functions (PDF).Five variables,water-cementitious materials ratio,content of cement,fly ash,aggregate and plasticizer,were employed for input variables,while a category of 56-d shrinkage of mortar was used for the output variable.A total of 192 groups of experimental data from 64 mixtures designed using JMP7.0 software were collected,of which 120 groups of data were used for training the model and the other 72 groups of data for *** simulation results showed that the PNN model with an optimal smoothing parameter determined by the curves of the mean square error (MSE) and the number of unrecognized probability densities (UPDs) exhibited a promising capability of predicting shrinkage of mortar.

关键词： Mortar Shrinkage Probabilistic neural networks (PNN) Thermal insulation

2011—2020年广州市肺结核死亡趋势及年龄-时期-队列模型分析

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中国防痨杂志 2025年第1期47卷 44-50页

作者：李雪秋刘群唐科吴迪广州市胸科医院结核病防治所一分所广州510095 广东省生物制品与药物研究所药理研究室广州510440 广州市疾病预防控制中心慢性非传染性疾病预防控制部广州510440 广东医科大学公共卫生学院东莞523808

目的:分析2011—2020年广州市肺结核患者的死亡情况和死亡率变化趋势,为制定防控策略和措施提供科学依据。方法:采用Joinpoint回归模型分析2011—2020年广州市全年龄段人群肺结核死亡率变化趋势,并计算年度变化百分比(annual percent ch... 详细信息

目的:分析2011—2020年广州市肺结核患者的死亡情况和死亡率变化趋势,为制定防控策略和措施提供科学依据。方法:采用Joinpoint回归模型分析2011—2020年广州市全年龄段人群肺结核死亡率变化趋势,并计算年度变化百分比(annual percent change,APC)和平均年度变化百分比(average annual percent change,AAPC);使用年龄-时期-队列模型分析广州市20~85岁人群肺结核死亡风险的年龄、时期和队列效应。结果:广州市2011—2020年报告肺结核死亡患者2144例,年均报告标化死亡率为2.57/10万;男性肺结核标化死亡率为4.19/10万,约为女性标化死亡率(0.96/10万)的4.4倍。10年间广州市肺结核年龄标化死亡率总体呈现下降趋势,AAPC为-4.15%(95%CI:-6.41%~-1.85%,P=0.003);其中,女性肺结核死亡率下降速度高于男性,AAPC分别为-6.72%(95%CI:-10.38%~-2.92%,P=0.004)和-3.55%(95%CI:-6.19%~-0.85%,P=0.017)。在不同年龄段人群中,0~49岁和≥65岁年龄段人群肺结核死亡率均呈现明显下降趋势,AAPC分别为-7.05%(95%CI:-11.52%~-2.34%,P=0.009)和-3.94%(95%CI:-6.22%~-1.62%,P=0.005)。年龄-时期-队列模型的年龄效应显示,随着年龄的增长,肺结核死亡风险不断上升,≥65岁人群尤为显著,发病率由66~67岁年龄组的2.93/10万增长至84~85岁年龄组的6.10/10万。时期效应显示,肺结核死亡风险随着时期的变化总体呈现下降趋势,相对危险度(risk ratio,RR)从2011—2012年时期组的1.35下降至2019—2020年时期组的0.81。队列效应显示,越晚出生的人群肺结核死亡风险越低,RR值从1926—1927年出生队列的5.91降低至1998—1999年出生队列的0.16。结论:广州市肺结核死亡率总体呈不断下降的趋势,但男性和女性肺结核死亡率差距较大。需重点关注男性和≥65岁年龄段的老年人群,并实施针对性的防控和治疗措施。

关键词：结核,肺死亡率回归分析队列研究

Efficacy of Wen-Luo-Tong on Peripheral Neuropathy Induced by Chemotherapy or Target Therapy: A Randomized, Double-Blinded, Placebo-Controlled Trial

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Chinese Journal of Integrative Medicine 2022年第7期28卷 579-585页

作者： deng Bo JIA li-qun WAN Dong-gui WANG Bao-yi CHENG Zhi-qiang deng Chao Center of Science and Technology China-Japan Friendship HospitalBeijing 100029China Integrative Oncology Department of Chinese Medicine and Western Medicine China-Japan Friendship HospitalBeijing 100029China

Objective: To evaluate the efficacy of Wen-Luo-Tong Granules(WLT) local administration in the treatment of patients with peripheral neuropathy(PN) induced by chemotherapy or target therapy. Methods: This study is a randomized, double-blinded, and placebo-controlled trial. Seventy-eight patients with PN induced by chemotherapy or target therapy were enrolled from China-Japan Friendship Hospital between July 2019 and January 2020. They were randomly assigned to WLT(39 cases) and control groups(39 cases) using a block randomization method. The WLT group received WLT(hand and foot bath) plus oral Mecobalamin for 1 week, while the control group received placebo plus oral Mecobalamin. The primary endpoint was PN grade evaluated by the National Cancer Institute-Common Toxicity Criteria for Adverse Events(NCI-CTCAE). The secondary endpoints included quantitative touch-detection threshold, neuropathy symptoms, Quality of life QuestionnaireChemotherapy Induced Peripheral Neuropathy(QLQ-CIPN20), and Quality of life Questionnaire-Core30(QLQ-C30). Results: After treatment, the PN grade in the WLT group was significantly lower than that in the control group(1.00±0.29 vs. 1.75±0.68, P<0.01). The total effective rate in the WLT group was significantly higher than that in the control group(82.05% vs. 51.28%, P<0.01). Compared with the control group, the touchdetection thresholds at fingertips, neuropathy symptom score, QLQ-CIPN 20(sensory scale, motor scale, autonomic scale, and sum score), and QLQ-C30(physical functioning, role functioning, emotional functioning, and global health) in the WLT group significantly improved after treatment(P<0.01 or P<0.05). Conclusion: WLT local administration was significantly effective in the treatment of patients with PN induced by chemotherapy or target therapy.(Trial registration No. ChiCTR1900023862)

关键词： peripheral neuropathy chemotherapy target therapy Chinese medicine Wen-Luo-Tong randomized controlled trial

Chondroitinase ABC combined with Schwann cell transplantation enhances restoration of neural connection and functional recovery following acute and chronic spinal cord injury

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Neural Regeneration Research 2025年第5期20卷 1467-1482页

作者： Wenrui Qu Xiangbing Wu Wei Wu Ying Wang Yan Sun lingxiao deng Melissa Walker Chen Chen Heqiao Dai Qi Han Ying Ding Yongzhi Xia George Smith Rui li Nai-Kui liu Xiao-Ming Xu Spinal Cord and Brain Injury Research Group Stark Neurosciences Research InstituteDepartment of Neurological SurgeryIndiana University School of MedicineIndianapolisINUSA Department of Hand Surgery the Second Hospital of Jilin UniversityChangchunJilin ProvinceChina Shriners Hospitals Pediatric Research Center Temple University School of MedicinePhiladelphiaPAUSA Department of Anatomy&Cell Biology Indiana University School of MedicineIndianapolisINUSA

Schwann cell transplantation is considered one of the most promising cell-based therapy to repair injured spinal cord due to its unique growth-promoting and myelin-forming properties.A the Food and Drug Administration-approved Phase I clinical trial has been conducted to evaluate the safety of transplanted human autologous Schwann cells to treat patients with spinal cord injury.A major challenge for Schwann cell transplantation is that grafted Schwann cells are confined within the lesion cavity,and they do not migrate into the host environment due to the inhibitory barrier formed by injury-induced glial scar,thus limiting axonal reentry into the host spinal *** we introduce a combinatorial strategy by suppressing the inhibitory extracellular environment with injection of lentivirus-mediated transfection of chondroitinase ABC gene at the rostral and caudal borders of the lesion site and simultaneously leveraging the repair capacity of transplanted Schwann cells in adult rats following a mid-thoracic contusive spinal cord *** report that when the glial scar was degraded by chondroitinase ABC at the rostral and caudal lesion borders,Schwann cells migrated for considerable distances in both rostral and caudal *** Schwann cell migration led to enhanced axonal regrowth,including the serotonergic and dopaminergic axons originating from supraspinal regions,and promoted recovery of locomotor and urinary bladder ***,the Schwann cell survival and axonal regrowth persisted up to 6 months after the injury,even when treatment was delayed for 3 months to mimic chronic spinal cord *** findings collectively show promising evidence for a combinatorial strategy with chondroitinase ABC and Schwann cells in promoting remodeling and recovery of function following spinal cord injury.

关键词： axonal regrowth bladder function chondroitinase ABC functional recovery glial scar lentivirus migration Schwann cell spinal cord injury transplantation