检索结果-南通市图书馆

Groundwater recharge via precipitation in the Badain Jaran Desert,China

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Groundwater Science and Engineering 2024年第1期12卷 109-118页

作者： Zhe wang li-juan wang Jian-mei Shen Zhen-long Nie Le Cao ling-qun Meng Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuang 050061China Technology Innovation Center for Geothermal&Hot Dry Rock Exploration and Development Ministry of Natural ResourcesShijiazhuang 050061China

Precipitation infiltration serves as a significant source of groundwater in the Badain Jaran *** investigate variations in precipitation infiltration within the desert,this study collected data on moisture content and temperature from the vadose zone through in-situ field *** these data,a numerical model is employed to explore the mechanism of groundwater recharge via *** results are as follows:(1)Moisture content and temperature in the shallow vadose zone exhibit significant seasonal variations,with moisture content diminishing with increasing depth;(2)Groundwater recharge via precipitation infiltration initially increases and then decreases with groundwater level depth(GWD).Peak groundwater recharge via precipitation occurs at a GWD of 0.75 m,decreasing to merely 0.012 cm at GWDs exceeding 2 m;(3)Groundwater is no longer susceptible to phreatic water evaporation when the GWD reaches approximately 3.7 ***,GWD plays a crucial role in governing groundwater recharge via precipitation in the Badain Jaran Desert.

关键词： Badain Jaran Desert Vadose zone Groundwater recharge In situ monitoring Numerical simulation

Prognostic prediction model of colorectal cancer based on preoperative serum tumor markers

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Surgery 2024年第5期16卷 1344-1353页

作者： Yu-Hang Diao Si-Qi Rao Xin-Peng Shu Yong Cheng Can Tan li-juan wang Dong Peng Department of Gastrointestinal Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

BACKGROUND Preoperative serum tumor markers not only play a role in the auxiliary diagnosis and postoperative monitoring in colorectal cancer(CRC),but also have been found to have potential prognostic *** To analyze whether preoperative serum tumor markers,including carcinoembryonic antigen(CEA)and carbohydrate antigen 19-9(CA19-9),affect the prognosis of *** This was a retrospective study conducted in a single *** with nonmetastatic CRC who underwent initial surgery between January 2011 and January 2020 were enrolled and divided into development site and validation site groups at a ratio of 7:*** independent prognostic factors were screened by Cox regression analysis,and finally,a prognostic nomogram model was *** newly developed model was tested by internal *** Eventually,3526 postoperative patients with nonmetastatic CRC were included in the *** were 2473 patients at the development site and 1056 patients at the validation ***(Plidation sites were 0.655 and 0.658,*** calibration plot also showed the significant performance of the newly established *** We successfully constructed a nomogram model based on age,TNM stage,preoperative CEA,and CA19-9 levels to evaluate the overall survival of patients with nonmetastatic CRC.

关键词： Colorectal cancer Prognosis Carcinoembryonic antigen Carbohydrate antigen 19-9 Nomogram

Preoperative albumin-bilirubin score predicts short-term outcomes and long-term prognosis in colorectal cancer patients undergoing radical surgery

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Surgery 2024年第7期16卷 2096-2105页

作者： Yu-Hang Diao Xin-Peng Shu Can Tan li-juan wang Yong Cheng Department of Gastrointestinal Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

BACKGROUND The albumin-bilirubin(ALBI)score is a serum biochemical indicator of liver function and has been proven to have prognostic value in a variety of *** colorectal cancer(CRC),a high ALBI score tends to be associated with poorer *** To investigate the correlation between the preoperative ALBI score and outcomes in CRC patients who underwent radical *** Patients who underwent radical CRC surgery between January 2011 and January 2020 at a single clinical center were *** ALBI score was calculated by the formula(log10 bilirubin×0.66)+(albumin×-0.085),and the cutoff value for grouping patients *** short-term outcomes,overall survival(OS),and disease-free survival(DFS)were *** A total of 4025 CRC patients who underwent radical surgery were enrolled in this study,and there were 1908 patients in the low ALBI group and 2117 patients in the high ALBI *** regression analysis revealed that age,tumor size,tumor stage,ALBI score,and overall complications were independent risk factors for OS;age,tumor stage,ALBI score,and overall complications were identified as independent risk factors for *** A high preoperative ALBI score is correlated with adverse short-term outcomes,and the ALBI score is an independent risk factor for OS and DFS in patients with CRC undergoing radical surgery.

关键词： Colorectal cancer Albumin-bilirubin score Overall survival Disease-free survival Outcomes

Non-coding RNAs:The potential biomarker or therapeutic target in hepatic ischemia-reperfusion injury

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

世界胃肠病学杂志:英文版 2023年第33期29卷 4927-4941页

作者： Jia-li Shao li-juan wang Ji Xiao Jin-Feng Yang Department of Anesthesiology The Affiliated Cancer Hospital of Xiangya School of MedicineCentral South UniversityChangsha 410013Hunan ProvinceChina

Hepatic ischemia-reperfusion injury(HIRI)is the major complication of liver surgery and liver transplantation,that may increase the postoperative morbidity,mortality,tumor progression,and *** underlying mechanisms have been extensively investigated in recent *** these,oxidative stress,inflammatory responses,immunoreactions,and cell death are the most ***-coding RNAs(ncRNAs)are defined as the RNAs that do not encode proteins,but can regulate gene *** recent years,ncRNAs have emerged as research hotspots for various *** the progression of HIRI,ncRNAs are differentially expressed,while these dysregulations of ncRNAs,in turn,have been verified to be related to the above pathological processes involved in *** mainly contain microRNAs,long ncRNAs,and circular RNAs,some of which have been reported as biomarkers for early diagnosis or assessment of liver damage severity,and as therapeutic targets to attenuate ***,we briefly summarize the common pathophysiology of HIRI,describe the current knowledge of ncRNAs involved in HIRI in animal and human studies,and discuss the potential of ncRNA-targeted therapeutic *** the scarcity of clinical trials,there is still a long way to go from pre-clinical to clinical application,and further studies are needed to uncover their potential as therapeutic targets.

关键词： Hepatic ischemia-reperfusion injury Non-coding RNAs MicroRNAs Long non-coding RNAs Circular RNAs

A novel aged mouse model of recurrent intracerebral hemorrhage in the bilateral striatum

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2023年第2期18卷 344-349页

作者： li-Min wang Zhi-Hua liu Hong-Lei Ren Xue-Mei Chen Jun-Min wang Hui-Min Cai li-Ping Wei Hui-Hong Tian Jian wang li-juan wang The Second School of Clinical Medicine Southern Medical UniversityGuangzhouGuangdong ProvinceChina Department of Neurology Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangdong Neuroscience InstituteGuangzhouGuangdong ProvinceChina School of Medicine South China University of TechnologyGuangzhouGuangdong ProvinceChina Department of Neurology Tianjin Neurological InstituteTianjin Medical University General HospitalTianjinChina Department of Anatomy School of Basic Medical SciencesZhengzhou UniversityZhengzhouHenan ProvinceChina

The current animal models of stroke primarily model a single intracerebral hemorrhage(ICH)attack,and there is a lack of a reliable model of recurrent *** this study,we established 16-month-old C57 B L/6 male mouse models of ICH by injecting collagenaseⅦ-S into the left ***-one days later,we injected collagenaseⅦ-S into the right striatum to simulate recurrent *** results showed that mice subjected to bilateral striatal hemorrhage had poorer neurological function at the early stage of hemorrhage,delayed recovery in locomotor function,motor coordination,and movement speed,and more obvious emotional and cognitive dysfunction than mice subjected to unilate ral striatal *** findings indicate that mouse models of bilateral striatal hemorrhage can well simulate clinically common recurrent *** models should be used as a novel tool for investigating the pathogenesis and treatment targets of recurrent ICH.

关键词： animal model cognition impairment depression-like behavior dopaminergic neurons emotion intracerebral hemorrhage motor neurologic function recurrent intracerebral hemorrhage

Fully distributed dynamic event-triggered formation-containment tracking for multiagent systems with multiple types of disturbances

在线全文

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2024年第1期67卷 168-186页

作者： Weihua li Huaguang ZHANG juan ZHANG Rui wang College of Information Science and Engineering Northeastern University State Key Laboratory of Synthetical Automation for Process Industries Northeastern University

This paper is dedicated to addressing the time-varying output formation-containment tracking(TVOFCT) problem for heterogeneous linear multiagent systems(MASs) with multiple types of disturbances under directed communication *** agents are divided into tracking leaders,formation leaders,and *** the output space,the formation leaders are required to form an expected geometric formation while tracking the tracking leader,and the followers are required to enter the convex hull spanned by formation ***,a disturbance observer is designed to observe the disturbance with deterministic ***,by combining adaptive technology with event-triggered technology,an independent fully distributed dynamic event-triggered(FDDET) compensator is designed to estimate the state of the tracking *** main advantages of this compensator lie in the following three aspects:(1) the adaptive weight does not increase unboundedly;(2) the interval time between events is expanded;(3) the design does not rely on any global *** to the design of this compensator,an independent FDDET convex hull observer is further designed to observe the convex hull spanned by formation ***,based on the designed disturbance observer,compensator,and convex hull observer,the adaptive disturbance rejection control input which can make the MASs achieve TVOFCT is ***,a numerical simulation is provided to clearly verify the validity of the theoretical results.

关键词： formation-containment tracking disturbance rejection multiagent systems fully distributed control dynamic event-triggered control

A new peptide,VD11,promotes structural and functional recovery after spinal cord injury

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2023年第10期18卷 2260-2267页

作者： Shan-Shan li Bai-Yu Zhang Sai-Ge Yin Zi-Qi Wei Nai-Xin liu Yi-lin li Si-Yu wang Yu-Heng Shi Jian Zhao li-juan wang Yue Zhang Jun Sun Ying wang Xin-wang Yang Department of Anatomy and Histology&Embryology Faculty of Basic Medical ScienceKunming Medical UniversityKunmingYunnan ProvinceChina Key Laboratory of Chemistry in Ethnic Medicinal Resources&Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal Endophytes State Ethnic Affairs Commission&Ministry of EducationSchool of Ethnic MedicineYunnan Minzu UniversityKunmingYunnan ProvinceChina Department of Urology First Affiliated Hospital of Kunming Medical UniversityKunmingYunnan ProvinceChina Yunnan Province Clinical Research Center for Chronic Kidney Disease First Affiliated Hospital of Kunming Medical UniversityKunmingYunnan ProvinceChina

The regenerative capacity of the central nervous system is very limited and few effective treatments are currently available for spinal cord *** is therefore a priority to develop new drugs that can promote structural and functional recovery after spinal cord *** studies have shown that peptides can promote substantial repair and regeneration of injured *** amphibians have a pronounced ability to regenerate the spinal cord,few studies have investigated the effect of amphibian spinal cord-derived peptides on spinal cord *** we report for the first time the successful identification and isolation of a new polypeptide,VD11(amino acid sequence:VDELWPPWLPC),from the spinal cord of an endemic Chinese amphibian(Odorrana schmackeri).In vitro experiments showed that VD11 promoted the secretion of nerve growth factor and brain-derived neurotrophic factor in BV2 cells stimulated with lipopolysaccharide,as well as the proliferation and synaptic elongation of PC12 cells subjected to *** vivo experiments showed that intravertebral injection of VD11 markedly promoted recovery of motor function in rats with spinal cord injury,alleviated pathological damage,and promoted axonal ***,RNA sequencing and western blotting showed that VD11 may affect spinal cord injury through activation of the AMPK and AKT signaling *** summary,we discovered a novel amphibian-derived peptide that promotes structural and functional recovery after spinal cord injury.

关键词： Akt signaling pathway amphibian-derived bioactive peptide AMPK signaling pathway axonal regeneration brain-derived neurotrophic factor ischemia/reperfusion injury motor function nerve growth factor neuroprotective effect spinal cord injury

Uncertainties of ENSO-related Regional Hadley Circulation Anomalies within Eight Reanalysis Datasets

在线全文

学校读者我要写书评

暂无评论

Advances in Atmospheric Sciences 2024年第1期41卷 115-140页

作者： Yadi li Xichen li juan FENG Yi ZHOU Wenzhu wang Yurong HOU International Center for Climate and Environment Sciences(ICCES) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China University of Chinese Academy of Sciences Beijing 101408China College of Global Change and Earth System Science(GCESS) Beijing Normal UniversityBeijing 100875China

El Nino-Southern Oscillation(ENSO),the leading mode of global interannual variability,usually intensifies the Hadley Circulation(HC),and meanwhile constrains its meridional extension,leading to an equatorward movement of the jet *** studies have investigated the response of HC to ENSO events using different reanalysis datasets and evaluated their capability in capturing the main features of ENSO-associated HC ***,these studies mainly focused on the global HC,represented by a zonal-mean mass stream function(MSF).Comparatively fewer studies have evaluated HC responses from a regional perspective,partly due to the prerequisite of the Stokes MSF,which prevents us from integrating a regional *** this study,we adopt a recently developed technique to construct the three-dimensional structure of HC and evaluate the capability of eight state-of-the-art reanalyses in reproducing the regional HC response to ENSO *** show that all eight reanalyses reproduce the spatial structure of HC responses well,with an intensified HC around the central-eastern Pacific but weakened circulations around the Indo-Pacific warm pool and tropical *** spatial correlation coefficient of the three-dimensional HC anomalies among the different datasets is always larger than ***,these datasets may not capture the amplitudes of the HC responses *** uncertainty is especially large for ENSO-associated equatorially asymmetric HC anomalies,with the maximum amplitude in Climate Forecast System Reanalysis(CFSR)being about 2.7 times the minimum value in the Twentieth Century Reanalysis(20CR).One should be careful when using reanalysis data to evaluate the intensity of ENSO-associated HC anomalies.

关键词： regional Hadley circulation ENSO atmosphere-ocean interaction reanalysis data

A general synthetic strategy for N, P co-doped graphene supported metal-rich noble metal phosphides for hydrogen generation

在线全文

学校读者我要写书评

暂无评论

Green Energy & Environment 2024年第1期9卷 152-162页

作者： Jingwen Ma Xiang li Guangyu Lei Jun wang juan wang Jian liu Ming Ke Yang li Chunwen Sun School of Chemical and Environmental Engineering China University of Mining and Technology(Beijing)Beijing100083China State Key Laboratory of Heavy Oil Processing China University of PetroleumBeijing102249China Lab of Advanced Nano-structures&Transfer Processes Department of Chemical EngineeringTianjin UniversityTianjin300354China PetroChina Planning and Engineering Institute Beijing100083China

The exploitation of electrocatalysts with high activity and durability for HER is desirable for future energy systems,but it is still a *** have attracted increasing attentions,but the preparation process often needs toxic regents or dangerous reaction ***,we develop a general green method to fabricate metal-rich NMPs anchored on NPG through pyrolyzing DNA cross-linked *** obtained Ru_(2) P-NPG exhibits an ultrasmall overpotential of 7 mV at 10 mA cm^(2) and ultralow Tafel slope of 33 mV dec^(-1) in 1.0 mol L?1 KOH,even better than that of commercial Pt/*** addition,Ru 2 P-NPG also shows low overpotentials of 29 and 78 mV in 0.5 mol L^(-1) H_(2)SO_(4) and 1.0 mol L^(-1) PBS,*** superior activity can be attributed to the ultrafine dispersion of Ru 2 P nanoparticles for more accessible sites,more defects formed for abundant active sites,the two-dimensional plane structure for accelerated electron transfer and mass transport,as well as the regulation of electron distribution of the ***,the synthetic method can also be applied to prepare other metal-rich noble metal phosphides(Pd_(3)P-NPG and Rh_(2)P-NPG),which also exhibits high activity for *** work provides an effective strategy for designing NMP-based electrocatalysts.

关键词： Noble metal phosphides Electrocatalyst Deoxyribonucleic acid Hydrogen evolution pH universal