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Development of Integrative Medicine in Hong Kong,China

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Chinese Journal of Integrative Medicine 2017年第7期23卷 486-489页

作者： leung Ting hung Wendy Wong School of Chinese Medicine The Chinese University of Hong Kong Hong Kong SAR China Hong Kong Institute of Integrative Medicine The Chinese University of Hong KongHong Kong SAR China

Upon reflection on the experience of integration of Chinese medicine（CM）and Western medicine（integrative medicine）in the China's Mainland in recent decades,this paper aims to review the recent developments of CM a... 详细信息

关键词： integrative Mainland collaboration disciplines challenging curriculum university heritage medicines deviation

A Novel OFDM Receiver with Optimum Second Order Polynomial Nyquist Windowing

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The Journal of China Universities of Posts and Telecommunications 2006年第2期13卷 84-89,102页

作者： SONG Rong-fang AI Si leung Shu-hung College of Telecommunications and Information Engineering Nanjing University of P~ts and Telecommunications Nanjing 210003 P.R. China National Mobile Communications Research Laboratory Southeast University Nanjing 210096 P.R. China Department of Electronic Engineering City University of Hong Kong Kowloon Hong Kong P.R. China

This paper proposes a new receive scheme and a class of time domain second order polynomial Nyquist window functions, and applies them to Orthogonal Frequency-Division Multiplexing （ OFDM ） systems in order to reduce Inter-Carrier Interference （ICI） induced by frequency offset. This paper also analyzes the Signal to ICI plus Noise Ratio （SINR） and Bit Error Rate （BER） performances of the receiver. Additionally, this paper proposes a method to select optimum window parameters to maximize the SINR of the receiver thus providing an adaptive receiving capability. Our results show that the proposed method enables the use of unity roll-off factor, provides better SINR and BER than conventional receive methods whose roll-off factors are generally less than one. The new second order polynomial window is shown to provide better performance than raised cosine and ＂better than ＂ Nyquist window.

关键词： OFDM Nyquist window inter-carrier interference carrier frequency offset

Asymptotic false discovery control of the Benjamini-Hochberg procedure for pairwise comparisons

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Science China Mathematics 2025年第1期 223-252页

作者： Weidong Liu Dennis leung Qi-Man Shao School of Mathematical Sciences Shanghai Jiao Tong University School of Mathematics and Statistics University of Melbourne Department of Statistics and Data Science SICMSouthern University of Science and Technology

In a one-way analysis-of-variance(ANOVA) model,the number of pairwise comparisons can become large even with a moderate number of *** by this,we consider a regime with a growing number of groups and prove that,when testing pairwise comparisons,the Benjamini-Hochberg(BH) procedure can asymptotically control false discoveries,despite the fact that the involved t-statistics do not exhibit the wellknown positive dependence structure required for exact false discovery rate(FDR) *** Tukey's perspective that the difference between the means of any two groups cannot be exactly zero,our main result provides control over the directional false discovery rate and directional false discovery proportion.A key technical contribution of our work is demonstrating that the dependence among the t-statistics is sufficiently weak to establish the convergence result typically required for asymptotic FDR *** analysis does not rely on conventional assumptions such as normality,variance homogeneity,or a balanced design,thereby offering a theoretical foundation for applications in more general settings.

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Polyethylene glycol fusion repair of severed sciatic nerves accelerates recovery of nociceptive sensory perceptions in male and female rats of different strains

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Neural Regeneration Research 2025年第9期20卷 2667-2681页

作者： Liwen Zhou Karthik Venkudusamy Emily A.Hibbard Yessenia Montoya Alexa Olivarez Cathy Z.Yang Adelaide leung Varun Gokhale Guhan Periyasamy Zeal Pathak Dale R.Sengelaub George D.Bittner Department of Neuroscience University of TexasAustinTXUSA Program in Neuroscience Indiana UniversityBloomingtonINUSA Department of Molecular Biosciences University of TexasAustinTXUSA

Successful polyethylene glycol fusion(PEG-fusion)of severed axons following peripheral nerve injuries for PEG-fused axons has been reported to:(1)rapidly restore electrophysiological continuity;(2)prevent distal wallerian Degeneration and maintain their myelin sheaths;(3)promote primarily motor,voluntary behavioral recoveries as assessed by the Sciatic Functional Index;and,(4)rapidly produce correct and incorrect connections in many possible combinations that produce rapid and extensive recovery of functional peripheral nervous system/central nervous system connections and reflex(e.g.,toe twitch)or voluntary *** preceding companion paper describes sensory terminal field reo rganization following PEG-fusion repair of sciatic nerve transections or ablations;howeve r,sensory behavioral recovery has not been explicitly explored following PEG-fusion *** the current study,we confirmed the success of PEG-fusion surgeries according to criteria(1-3)above and more extensively investigated whether PEG-fusion enhanced mechanical nociceptive recovery following sciatic transection in male and female outbred Sprague-Dawley and inbred Lewis *** nociceptive responses were assessed by measuring withdrawal thresholds using von Frey filaments on the dorsal and midplantar regions of the *** von Frey filament tests were a more reliable method than plantar von Frey filament tests to assess mechanical nociceptive sensitivity following sciatic nerve *** withdrawal thresholds of the sciatic-mediated lateral dorsal region differed significantly across strain but not *** thresholds did not change significantly from baseline in chronic Unoperated and Sham-operated *** sciatic transection,all rats exhibited severe hyposensitivity to stimuli at the lateral dorsal region of the hindpaw ipsilateral to the ***,PEG-fused rats exhibited significantly earlier return to baseline withdrawal thresholds than Negative

关键词： autophagia axotomy collateral sprouting neuropathic pain peripheral nerve repair polyethylene glycol fusion(PEG-fusion) saphenous nerve sensory neurons sex and strain wallerian degeneration

Message from Deputy Editor-in-Chief Gabriel M leung—International Trade and Global Health Protection

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China CDC weekly 2019年第4期1卷 45-46页

作者： Gabriel M leung China CDC Weekly Dean of Medicine The University of Hong KongHong Kong SARChina

It was external trade that first prompted the collection and reporting of surveillance data at the foreign ports from which the US imported *** established Bulletin of the Public Health—the first precursor to the US ... 详细信息

关键词： Trade prompt Health

Chinese topical herbal medicine gives additive effect on pharmaceutical agent on fracture healing

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Journal of Traditional Chinese Medicine 2019年第6期39卷 853-860页

作者： Siu Wing Sum Shiu Hoi Ting Shum wai Ting Ko Chun Hay Lau Clara Bik San hung leung Kim leung Ping Chung Institute of Chinese Medicine The Chinese University of Hong KongShatinNew TerritoriesHong Kong China State Key Laboratory of Research on Bioactivities and Clinical Applications of Medicinal Plants The Chinese University of Hong KongShatinNew TerritoriesHong Kong China Department of Orthopaedics and Traumatology The Chinese University of Hong KongShatinNew TerritoriesHong Kong China

OBJECTIVE:To investigate the efficacy on the combination of oral strontium ranelate(Sr R)with a topical Chinese herbal paste on facilitation of fracture ***:An open fracture was created at the mid-shaft of the right tibia of rat.A herbal pastecalled CDR containing Honghua(Flos Carthami),Chuanxuduan(Radix Dipsaci Asperoidis)and Dahuang(Radix Et Rhizoma Rhei Palmati)was *** rats were treated with either CDR topically on the fracture site,or Sr R orally,or their *** turnover biochemical markers in serum were *** of the fracture was analyzed using micro-CT after 14 and 28 d,followed by histomorphometrical ***:Micro-computed tomography analysis revealed that the combined treatment of CDR with600 mg/g Sr R significantly increased the total callus density,mineralized callus volume fraction,mineralized callus mineral content and mineralized callus density of the callus after 28 d of *** result was consistent with the histomorphometrical analysis on the osteoid *** of biochemical markers showed that the combined treatments reduced the bone resorption that occurs temporarily after ***:This study demonstrated that the combined treatment of oral Sr R and topical CDR is effective to promote fracture healing by their additive effect on promoting bone formation and retarding bone resorption.

关键词： Fracture healing Osteogenesis Bone resorption Medicine,Chinese Traditional Integrative medicine Strontium ranelate

Acupuncture transcutaneous electrical nerve stimulation reduces discomfort associated with barostat-induced rectal distension:A randomized-controlled study

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World Journal of Gastroenterology 2013年第3期19卷 381-388页

作者： Wing-wa leung Alice YM Jones Simon SM Ng Cherry YN Wong Janet FY Lee Department of Rehabilitation Sciences The Hong Kong Polytechnic UniversityHung HomHong Kong 999077China Faculty of Health Sciences The University of SydneySydneyNSW 2006Australia Division of Colorectal Surgery Department of SurgeryThe Chinese University of Hong KongPrince of Wales HospitalShatinHong Kong 999077China

AIM:To explore the effectiveness of acupuncture transcutaneous electrical nerve stimulation(Acu-TENS), a non-invasive modality in reduction of rectal discomfort during barostat-induced rectal distension. METHODS:Forty healthy subjects were randomized to receive 45 min of either Acu-TENS or placebo-TENS(no electrical output)over acupuncture points Hegu(largeintestine 4),Neiguan(pericardium 6)and Zusanli(stomach 36).A balloon catheter attached to a dual-drive barostat machine was then inserted into the subjects'rectum.A step-wise(4 mmHg)increase in balloon pressure was induced until maximal tolerable or 48 *** analogue scale and a 5-point subjective discomfort scale(no perception,first per-ception of distension,urge to defecate,discomfort/ pain and extreme pain)were used to assess rectal discomfort at each distension *** beta-endorphin levels were measured before,immediately after intervention,at 24 mmHg and at maximal toler- able distension pressure. RESULTS:There was no difference in the demographic data and baseline plasma beta-endorphin levels between the two *** threshold levels were higher in the Acu-TENS group when compared to the placebo group,but the difference reached statistical significance only at the sensations"urge to defecate"and"pain".The distension pressures recorded at the"urge to defecate"sensation for the Acu-TENS and placebo-TENS groups were 28.0±4.5 mmHg and 24.6±5.7 mmHg,respectively(P=0.043);and the pressures recorded for the"pain"sensation for these two groups were 36.0±4.2 mmHg and 30.5± 4.3 mmHg respectively(P=0.002).Compared to the placebo group,a higher number of participants in the Acu-TENS group tolerated higher distension pressures (>40 mmHg)(65%in Acu-TENS vs 25%in placebo, P=0.02).The plasma beta-endorphin levels of the Acu-TENS group were significantly higher than that of the placebo group at barostat inflation pressure of 24 mmHg(1.31±0.40 ng/mL vs 1.04±0.43 ng/mL,P= 0.044)and at maximal inflation p

关键词： Colonoscopy Rectal discomfort Transcu-taneous electrical nerve stimulation Acupuncture Visceral pain

Soft Computing Based Procurement Planning of Time-variable Demand in Manufacturing Systems

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International Journal of Automation and computing 2007年第1期4卷 80-87页

作者： Kai leung Yung wai hung Ip Ding-Wei wang Department of Industrial and Systems Engineering Hong Kong Polytechnic University Hung Horn Kowloon Hong Kong PRC School of Information Science and Engineering Northeastern University Shenyang 110004 PRC

Procurement planning with discrete time varying demand is an important problem in Enterprise Resource Planning （ERP）. It can be described using the non-analytic mathematical programming model proposed in this paper. To solve the model we propose to use a fuzzy decision embedded genetic algorithm. The algorithm adopts an order strategy selection to simplify the original real optimization problem into binary ones. Then, a fuzzy decision quantification method is used to quantify experience from planning experts. Thus, decision rules can easily be embedded in the computation of genetic operations. This approach is applied to purchase planning problem in a practical machine tool works, where satisfactory results have been achieved.

关键词： Purchase planning Enterprise Resource Planning (ERP) soft computing genetic algorithm fuzzy decision inventory control.

Difficulty with diagnosis of malignant pancreatic neoplasms coexisting with chronic pancreatitis

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World Journal of Gastroenterology 2005年第32期11卷 5075-5078页

作者： Ting-Kai leung Chi-Ming Lee Fong-Chieh wang Hsin-Chi Chen hung-Jung wang Department of Diagnostic RadiologyTaipei Medical University Hospital Taiwan Department of Internal Medicine Taipei Medical University HospitalTaiwanChina

Chronic pancreatitis is a relatively common disease. We encountered two different cases of belatedly demonstrated pancreatic carcinoma featuring underlying chronic pancreatitis. The first case was one that was highly suspected as that of a malignancy based upon imaging study, but unfortunately, it could not be confirmed by intra-operative cytology at that time. Following this, the surgeon elected to perform only conservative bypass surgery for obstructive biliary complication. Peritoneal carcinomatosis was later noted and the patient finally died. The second case, a malignant mucinous neoplasm,was falsely diagnosed as a pseudocyst, based upon the lesion's sonographic appearance and associated elevated serum amylase levels. After suffering repeated hemoptysis,the patient was found to exhibit lung metastasis and peritoneal seeding. We reviewed some of the literature,including those studies discussing chronic pancreatitis predisposing to a malignant change. These two case analyses illustrate clearly that the diagnosis for such conditions, which is simply based upon imagery or pathological considerations may end up being one of a mistaken malignancy. Some of our suggestions for the treatment of such malignancies as revealed herein include,total pancreatomy for univocal mass lesion, and needle aspiration of lesion-contained tissue for amylase, CA199and CEA levels for a suspicious cystic pancreatic mass.

关键词： Mucinous cystic neoplasm Pancreatic carcinoma Pseudocyst Pancreatic adenocarcinoma Chronic pancreatitis