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Dynamic multifunctional metasurfaces:an inverse design deep learning approach

Photonics Research 2024年第1期12卷 123-133页

作者： ZHI-DAN lei YI-DUO XU cheng lei YAN ZHAO DU WANG The Institute of Technological Sciences Wuhan UniversityWuhan 430072China College of Materials Science and Engineering Sichuan UniversityChengdu 610065China

Optical metasurfaces(OMs)offer unprecedented control over electromagnetic waves,enabling advanced optical *** emergence of deep learning has opened new avenues for designing ***,existing deep learning methods for OMs primarily focus on forward design,which limits their design capabilities,lacks global optimization,and relies on prior ***,most OMs are static,with fixed functionalities once *** overcome these limitations,we propose an inverse design deep learning method for dynamic *** approach comprises a forward prediction network and an inverse retrieval *** forward prediction network establishes a mapping between meta-unit structure parameters and reflectance *** inverse retrieval network generates a library of meta-unit structure parameters based on target requirements,enabling end-to-end design of *** incorporating the dynamic tunability of the phase change material Sb2Te3with inverse design deep learning,we achieve the design and verification of dynamic multifunctional *** results demonstrate OMs with multiple information channels and encryption capabilities that can realize multiple physical field optical modulation *** Sb2Te3is in the amorphous state,near-field nano-printing based on meta-unit amplitude modulation is achieved for X-polarized incident light,while holographic imaging based on meta-unit phase modulation is realized for circularly polarized *** the crystalline state,the encrypted information remains secure even with the correct polarization input,achieving double *** research points towards ultra-compact,high-capacity,and highly secure information storage approaches.

关键词： polarization inverse approach

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Degradation analysis and doping modification optimization for high-voltage P-type layered cathode in sodium-ion batteries

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Journal of Energy Chemistry 2024年第2期89卷 1-9,I0002页

作者： Bao Zhang Yi Zhao Minghuang Li Qi Wang lei cheng lei Ming Xing Ou Xiaowei Wang National Engineering Laboratory for High-Efficiency Recovery of Refractory Nonferrous Metals School of Metallurgy and EnvironmentCentral South UniversityChangsha 410083HunanChina Zhejiang Power New Energy Co. LTDZhuji 311800ZhejiangChina

Advancing high-voltage stability of layered sodium-ion oxides represents a pivotal avenue for their progress in energy storage *** this,a comprehensive understanding of the mechanisms underpinning their structural deterioration at elevated voltages remains insufficiently *** this study,we unveil a layer delamination phenomenon of Na_(0.67)Ni_(0.3)Mn_(0.7)O_(2)(NNM)within the 2.0-4.3 V voltage,attributed to considerable volumetric fluctuations along the c-axis and lattice oxygen reactions induced by the simultaneous Ni^(3+)/Ni^(4+)and anion redox *** introducing Mg doping to diminished Ni-O antibonding,the anion oxidation-reduction reactions are effectively mitigated,and the structural integrity of the P2 phase remains firmly intact,safeguarding active sites and precluding the formation of novel *** Na_(0.67)Mg_(0.05)Ni_(0.25)Mn_(0.7)O_(2)(NMNM-5)exhibits a specific capacity of100.7 mA h g^(-1),signifying an 83%improvement compared to the NNM material within the voltage of2.0-4.3 *** investigation underscores the intricate interplay between high-voltage stability and structural degradation mechanisms in layered sodium-ion oxides.

关键词： Soidum ion batteries Layer cathode materials P-type High-voltage performance Degradation analysis

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Global gene expression profiling of perirenal brown adipose tissue whitening in goat kids reveals novel genes linked to adipose remodeling

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Journal of Animal Science and Biotechnology 2024年第3期15卷 1008-1026页

作者： Le Zhao Haili Yang Minhao Li Min Xiao Xingchun Li lei cheng Wenqiang cheng Meixi Chen Yongju Zhao College of Animal Science and Technology Southwest UniversityChongqing Key Laboratory of Herbivore ScienceChongqing 400715China

Background Brown adipose tissue(BAT)is known to be capable of non-shivering thermogenesis under cold stimulation,which is related to the mortality of *** the previous study,we observed that goat BAT is mainly located around the kidney at birth,and changes to white adipose tissue(WAT)in the perirenal adipose tissue of goats within one month after ***,the regulatory factors underlying this change is remain *** this study,we systematically studied the perirenal adipose tissue of goat kids in histological,cytological,and accompanying molecular level changes from 0 to 28 d after *** Our study found a higher mortality rate in winter-born goat kids,with goat birthing data *** we used thermal imaging revealing high temperature in goat hips at postnatal 0 d and gradually decrease during 28 *** is consistent with the region of perirenal BAT deposition and highlights its critical role in energy expenditure and body temperature regulation in goat ***,we found a series of changes of BAT during the first 28 d after birth,such as whitening,larger lipid droplets,decreased mitochondrial numbers,and down-regulation of key thermogenesis-related genes(UCP1,DIO2,UCP2,CIDEA,PPARGC1a,C/EBPb,and C/EBPa).Then,we used RNA-seq found specific marker genes for goat adipose tissue and identified 12 new marker genes for BAT and 10 new marker genes for WAT of ***,12 candidate genes were found to potentially regulate goat BAT *** mechanism of the change of this biological phenomenon does not involve a large-scale death of brown adipocytes and subsequent proliferation of white *** apoptosis may play a limited role,it is largely not critical in this transition *** We concluded that perirenal BAT plays a crucial role in thermoregulation in newborn goat kids,with notable species differences in the expression of adipose tissue marker genes,and we highlighted some potential marker genes

关键词： Adipose remodeling Brown adipose tissue Goat kids Key thermogenesis-related genes Whitening

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LncRNA-CCAT5-mediated crosstalk between Wnt/β-Catenin and STAT3 signaling suggests novel therapeutic approaches for metastatic gastric cancer with high Wnt activity

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Cancer Communications 2024年第1期44卷 76-100页

作者： Chenchen Liu Aiwen Shen Junquan Song lei cheng Meng Zhang Yanong Wang Xiaowen Liu Department of Gastric Surgery Fudan University Shanghai Cancer CenterShanghaiP.R.China Department of Oncology Shanghai Medical CollegeFudan UniversityShanghaiP.R.China Department of Nephrology Shanghai Ninth People’s HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghaiP.R.China Department of Pulmonary Shanghai Chest HospitalShanghai Jiao Tong UniversityShanghaiP.R.China Department of Pathology Fudan University Shanghai Cancer CenterShanghaiP.R.China

Background:Although the constitutively activated Wnt/β-catenin signaling pathway plays vital roles in gastric cancer(GC)progression,few Wnt inhibitors are approved for clinical ***,the clinical significance of long non-coding RNAs(lncRNAs)in GC intraperitoneal dissemination(IPD)remains ***,we investigated the function and therapeutic potential of Wnt-transactivated lncRNA,colon cancer-associated transcript 5(CCAT5),in GC ***:LncRNA-sequencing assay was performed to document abun-dance changes of lncRNAs induced by Wnt family member 3A(Wnt3a)and degradation-resistantβ-catenin(S33Y mutated)in ascites-derived GC cells with low Wnt *** reporter,Chromatin immunoprecipitation(ChIP)-re-ChIP assays were performed to determine how CCAT5 was *** clinical significance of CCAT5 was examined in 2 cohorts of GC *** biological function of CCAT5 was investigated through gain-and loss-of-function *** molecular mechanism was explored through RNA-sequencing,mass spectrometry,and CRISPR/Cas9-knocknout *** therapeutic potential of CCAT5 was examined through RNAi-based cell xenograft model and patient-derived xenograft(PDX)model of ***:WeidentifiedanovelWnt-regulatedlncRNA,CCAT5,whichwastrans-activated by theβ-catenin/transcription factor 3(TCF3)***5 was significantly upregulated in GC and predicted poor *** studies confirmed the promotive role of CCAT5 in GC growth and ***-tically,CCAT5 bound to the C-end domain of signal transducer and activator of transcription 3(STAT3)and blocks Src homology 2 domain-containing protein tyrosine phosphatase 1(SHP-1)-mediated STAT3 Y705 dephosphorylation,leading to STAT3 nuclear entry and transactivation,thus accelerating GC ***,we demonstrated that both Wnt3a andβ-catenin acted as activa-tor of STAT3 signaling pathway,and the interplay between CCAT5 and STAT3 was functionally essential for Wnt-

关键词： CCAT5 gastric cancer intraperitoneal dissemination STAT3 Wnt/β-catenin

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Whole-exome sequencing identified novel DNAH5 homozygous variants in two consanguineous families with primary ciliary dyskinesia

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中华医学杂志(英文版) 2024年第1期137卷 115-116页

作者： Yang Binyi lei cheng Xu Yingjie Yang Danhui Lu Chenyang Liu Ying Guo Ting Luo Hong Department of Pulmonary and Critical Care Medicine The Second Xiangya Hospital 3. Central South University 4. Changsha 5. Hunan 410011 6. China

Primary ciliary dyskinesia (PCD) is a rare autosomal recessive inherited disease characterized by dysfunction of the motile cilia. DNAH5, the most frequently mutated gene in PCD, encodes a heavy chain of the ciliary outer dynein arms (ODAs). Herein, we report two patients with Kartagener syndrome (sinusitis, bronchiectasis, and situs inversus) in two consanguineous families carrying two novel homozygous DNAH5 variants [Supplementary Figures 1A and 1B, http://***/CM9/B598].

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Piezo1 channel exaggerates ferroptosis of nucleus pulposus cells by mediating mechanical stress-induced iron influx

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Bone Research 2024年第2期12卷 334-348页

作者： Ziqian Xiang Pengfei Zhang Chunwang Jia Rongkun Xu Dingren Cao Zhaoning Xu Tingting Lu Jingwei Liu Xiaoxiong Wang cheng Qiu Wenyang Fu Weiwei Li lei cheng Qiang Yang Shiqing Feng Lianlei Wang Yunpeng Zhao Xinyu Liu Department of Orthopaedics Qilu Hospital of Shandong UniversityJinan 250012China University of Health and Rehabilitation Sciences Qingdao 226000China Xiangya School of Medicine Central South UniversityChangsha 410013China School of Nursing and Rehabilitation Shandong UniversityJinan 250012China Department of Pediatrics Cangzhou Central HospitalCangzhou 061011China Department of Pediatric Surgery Qilu Hospital of Shandong UniversityJinan 250012China Department of Pathology Qilu Hospital of Shandong UniversityJinan 250012China Department of Spine Surgery Tianjin HospitalTianjin UniversityTianjin 30021China The Second Hospital of Shandong University Cheeloo College of MedicineShandong UniversityJinan 250012China

To date,several molecules have been found to facilitate iron influx,while the types of iron influx channels remain to be ***,Piezo1 channel was identified as a key iron transporter in response to mechanical ***1-mediated iron overload disturbed iron metabolism and exaggerated ferroptosis in nucleus pulposus cells(NPCs).Importantly,Piezo1-induced iron influx was independent of the transferrin receptor(TFRC),a well-recognized iron ***,pharmacological inactivation of Piezo1 profoundly reduced iron accumulation,alleviated mitochondrial ROS,and suppressed ferroptotic alterations in stimulation of mechanical ***,conditional knockout of Piezo1(Col2a1-CreERT Piezo1^(flox/flox))attenuated the mechanical injury-induced intervertebral disc degeneration(IVDD).Notably,the protective effect of Piezo1 deficiency in IVDD was dampened in Piezo1/Gpx4 conditional double knockout(cDKO)mice(Col2a1-CreERT Piezo1^(flox/flox)/Gpx4^(flox/flox)).These findings suggest that Piezo1 is a potential determinant of iron influx,indicating that the Piezo1-iron-ferroptosis axis might shed light on the treatment of mechanical stress-induced diseases.

关键词： stress overload channel

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基于增量式Q学习的固定翼无人机跟踪控制性能优化

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控制与决策 2024年第2期39卷 391-400页

作者：赵振根程磊南京航空航天大学自动化学院南京211106

针对固定翼无人机纵向控制的高性能需求,提出一种控制系统性能优化结构.该结构包括一个使系统稳定的标称控制器和一个参与性能优化的增量式控制器.控制系统增量式的实现不会改变原有的控制系统,而是仅对标称控制系统做控制输入的补偿与... 详细信息

针对固定翼无人机纵向控制的高性能需求,提出一种控制系统性能优化结构.该结构包括一个使系统稳定的标称控制器和一个参与性能优化的增量式控制器.控制系统增量式的实现不会改变原有的控制系统,而是仅对标称控制系统做控制输入的补偿与控制性能的优化.基于Q学习理论进行增量式控制器设计,针对状态信息完全可获得的系统,设计一种基于状态反馈的增量式Q学习算法.当状态信息不能完全获得时,利用系统输入、输出和参考信号数据,设计一种基于输出反馈的增量式Q学习算法.两种增量式控制器均是在数据驱动环境下自适应学习增量式控制律,无需提前知道系统动力学模型以及标称控制器的控制增益.此外,证明了增量式Q学习方法在满足持续激励条件的激励噪声下,对Q函数贝尔曼方程的求解没有偏差.最后,通过对F-16飞行器纵向模型实例的仿真验证该方法的有效性.

关键词：强化学习 Q学习增量式控制性能优化跟踪控制无人机

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Countermeasure against blinding attack for single-photon detectors in quantum key distribution

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Journal of Semiconductors 2024年第4期45卷 76-81页

作者： Lianjun Jiang Dongdong Li Yuqiang Fang Meisheng Zhao Ming Liu Zhilin Xie Yukang Zhao Yanlin Tang Wei Jiang Houlin Fang Rui Ma lei cheng Weifeng Yang Songtao Han Shibiao Tang QuantumCTek Co. Ltd.Hefei 230088China Shandong Institute of Quantum Science and Technology Co. Ltd.Jinan 250101China QuantumCTek(Beijing)Co. Ltd.Beijing 100193China School of Cyber Science and Technology University of Science and Technology of ChinaHefei 230027China Anhui Armed Police Force Hefei 230026China School of Electrical Engineering and Automation Anhui UniversityHefei 230601China

Quantum key distribution(QKD),rooted in quantum mechanics,offers information-theoretic ***,practi-cal systems open security threats due to imperfections,notably bright-light blinding attacks targeting single-photon ***,we propose a concise,robust defense strategy for protecting single-photon detectors in QKD systems against blinding *** strategy uses a dual approach:detecting the bias current of the avalanche photodiode(APD)to defend against con-tinuous-wave blinding attacks,and monitoring the avalanche amplitude to protect against pulsed blinding *** integrat-ing these two branches,the proposed solution effectively identifies and mitigates a wide range of bright light injection attempts,significantly enhancing the resilience of QKD systems against various bright-light blinding *** method forti-fies the safeguards of quantum communications and offers a crucial contribution to the field of quantum information security.

关键词： quantum key distribution single photon detector blinding attack pulsed blinding attack countermeasure quan-tum communication

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中间层材料Fe和Nb对高强钛-钢复合管界面及剪切强度的影响

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金属学报 2024年第1期60卷 117-128页

作者：程磊张旭航韩盈程志诚余伟北京科技大学工程技术研究院北京100083

开发高强钛-钢复合管对于装备轻量化的研究具有重要意义。本工作采用高温挤压工艺制备以高强CrMo钢和TC11钛合金为基材的钛-钢复合管,研究了中间层材料Fe和Nb对高强钛-钢复合界面反应产物和结合强度的影响,并从界面扩散和组织演变的角... 详细信息

开发高强钛-钢复合管对于装备轻量化的研究具有重要意义。本工作采用高温挤压工艺制备以高强CrMo钢和TC11钛合金为基材的钛-钢复合管,研究了中间层材料Fe和Nb对高强钛-钢复合界面反应产物和结合强度的影响,并从界面扩散和组织演变的角度分析其断裂机制。结果表明:Fe中间层挤压态样品能够保持较高的剪切强度(185 MPa),在热处理过程中,Fe中间层析出的M_(23)C_(6)及钛基材的再结晶过程,导致界面剪切强度显著下降(70 MPa);Nb中间层920和970℃挤压态样品分别沿钢-Nb界面和Nb-钛界面断裂,这分别与钢-Nb界面处膜状NbC层的破裂和Nb-钛界面处β-Ti层的不连续特征相关,热处理后扩散修复的NbC层可使920℃挤压样品剪切强度从挤压态的131 MPa提升至170 MPa,而970℃挤压样品界面处不连续的β-Ti层以及Ti_(0.86)Al_(0.11)Nb_(0.03)析出颗粒的回溶,使其界面强度反而下降。综合界面反应和组织转变特征,明确了含2种中间层高强钛-钢复合管的微观断裂机制。

关键词：钛-钢复合管高温挤压中间层剪切强度析出

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Depositional process of hyperpycnal flow deposits:A case study on Lower Cretaceous Sangyuan outcrop in the Luanping Basin,Northeast China

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China Geology 2024年第3期7卷 505-516页

作者： De-zhi Yan Ru-kai Zhu Hao Shou Zhao-hui Xu Wei-hong Liu Si-cheng Zhu Zhi-cheng lei Jing-ya Zhang Chang Liu Yi Cai Huai-min Xu Research Institute of Petroleum Exploration and Development PetroChinaBeijing 100083China National Energy Tight Oil and Gas R&D Center Beijing 100083China PetroChina Key Laboratory of Oil and Gas Reservoir Beijing 100083China State Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum(Beijing)Beijing 102249China College of Geosciences China University of Petroleum(Beijing)Beijing 102249China Jiangxi Engineering Laboratory on Radioactive Geoscience and Big Data Technology Department of Information and EngineeringEast China University of TechnologyNanchang 330013China

Sedimentary process research is of great significance for understanding the distribution and characteristics of *** the detailed observation and measurement of the Sangyuan outcrop in Luanping Basin,this paper studies the depositional process of the hyperpycnal flow deposits,and divides their depositional process into three phases,namely,acceleration,erosion and *** the acceleration phase,hyperpycnal flow begins to enter the basin nearby,and then speeds up *** developed in the acceleration phase are *** addition,the original deposits become unstable and are taken away by hyperpycnal flows under the eroding *** a result,there are a lot of mixture of red mud pebbles outside the basin and gray mud pebbles within the *** the erosion phase,the reverse deposits are eroded and become thinner or even ***,no reverse grading characteristic is found in the proximal major channel that is closer to the source,but it is still preserved in the middle branch channel that is far from the *** entering the deceleration phase,normally grading deposits appear and cover previous *** final deposits in the basin are *** are reverse,and others are *** are superimposed with each other under the action of hyperpycnal *** analysis of the Sangyuan outcrop demonstrates the sedimentary process and distribution of hyperpycnites,and reasonably explain the sedimentary characteristics of *** is helpful to the prediction of oil and gas exploration targets in gravity flow deposits.

关键词： Hyperpycnal flow Sedimentary characteristics Depositional process Gravity flow deposit Hyperpycnite Red mud pebble Gray mud pebble Oil and gas exploration engineering Luanping Basin

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