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Seroprevalence of toxoplasmosis and rubella in pregnant women attending antenatal private clinic at Ouagadougou,Burkina Faso

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Asian Pacific Journal of Tropical Medicine 2012年第10期5卷 810-813页

作者： laure stella ghoma linguissi Bolni Marius Nagalo Cyrille Bisseye Thrse S Kagon Mahamoudou Sanou Issoufou Tao Victoire Benao Jacques Simpor Bibiane Kon Centre de Recherche Biomoleculaire Pietro Annigoni(CERBA/LABIOGENE) UFR/SVTUniversite de OuagadougouBurkina Faso Departement de Biologie Universite des Sciences et Techniques de MasukuFrancevilleGabon Centre MURAZ Bobo-DioulassoBurkina Faso Centre National de Transfusion Sanguine(CNTS) Ouagadougou.Burkina Faso Clinique Moussa Kone OuagadougouBurkina Faso Centre Medical Saint Camille OuagadougouBurkina Faso

Objective:To evaluate the prevalence of toxoplasmosis and rubella among pregnant women at Ouagadougou in Burkina ***:All patient sera were tested for rubella and toxoplasmosis anti-IgG using commercial ELISA kits(PlateliaTMRubella IgG and Platelia? Toxo IgG).The presence of anti-rubella and anti-toxoplasmosis tgM in serum samples was tested using commercial ELISA kits Platelia Rubella TgM and Platelia Toxo ***:Among all the pregnant women tested for toxoplasmosis and rubella,their prevalence were 20.3% and 77.0%,*** women in the age group of 18-25 years showed the highest frequency of anti-toxoplasmosis（34.5%） and anti-rubella IgG（84.6%）.The prevalence of anti-toxoplasma and anti-rubella IgG decreased between 2006 and 2008 from 32.7%to 12.1%and 84.6% to 65.0%,*** was no significant association between age and the mean titer of anti-toxoplasmosis IgG among pregnant ***:The diagnosis of toxoplasmosis and rubella is necessary in pregnant women in Burkina Faso because of the low immunization coverage rate of rubella and the high level of exposure to these two infections which can be harmful to the newborn if contracted by women before the third trimester of pregnancy.

关键词： IgG Toxoplasma gondii Rubella Seroprevalence Burkina Faso

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Diagnostic Performance of Five Rapid Serological Tests for SARS-CoV-2

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Open Journal of Epidemiology 2022年第4期12卷 470-480页

作者： Gilbert Ndziessi Jospeh Axel Ngatse Fabien Roch Niama Henriette Poaty Mayengue Pembe Issamou Fresnovie Geladore Mbele laure stella ghoma linguissi Francine Ntoumi Department of Public Health Faculty of Health Sciences University Marien Ngouabi Brazzaville Republic of the Congo National Laboratory of Public Health Brazzaville Republic of the Congo National Research Institute on Health Sciences Brazzaville Republic of the Congo Fondation Congolaise pour la Recherche Médicale Brazzaville Republic of the Congo

We conducted a study to evaluate the sensitivity (Se), specificity (Sp), positive predictive value (PPV), and negative predictive value (NPV) of five serologic tests. Subjects with negative or positive COVID-19 polymerase chain reaction (PRC) test results were tested with each of the serological tests. The results were compared with the reference PCR test. For the five tests evaluated, the Se ranged from 55.0% to 70.0% and the Sp ranged from 67.2% to 86.2%. PPV ranged from 53.2% to 80% and NPV from 75.0% to 86.2%. One test, the Wantai, had better specificity and sensitivity. None of the five tests had performance values of more than 90% in the entire sample. In symptomatic positive cases, the Wantai test reported excellent sensitivity. Overall, the low level of diagnostic performance of these tests does not support their use as an alternative to PCR for COVID-19 diagnostic. Test with better performance can be used for mass screening in low prevalence populations, to limit the indiscriminate use of PCR in context of resource-limited countries. Given the excellent sensitivity of Wantai in symptomatic cases, this test could be used as a referral test only in health facilities to discriminate suspected cases before PCR confirmation.

关键词： SARS-Cov-2 Seroprevalence Antibodies COVID-19 Congo

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Efficiency of HAART in the prevention of mother to children HIV-1 transmission at Saint Camille medical centre in Burkina Faso,West Africa

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Asian Pacific Journal of Tropical Medicine 2012年第12期5卷 991-994页

作者： laure stella ghoma linguissi Cyrille Bisseye Tani Sagna Bolni Marius Nagalo Djeneba Ouermi Florencia W Djigma Salvatore Pignatelli Joseph D Sia Virginio Pietra Remy Moret Jean Baptiste Nikiema Jacques Simpore Centre de Recherche Biomoleculaire Pietro Annigoni(CERBA)/LABIOGENE UFR/SVTUniversite de OuagadougouBurkina Faso Department de Biologie Unirersite des Sciences et Techniques de Masuku(USTM) FrancerilleGabon Centre Medical Saint Camille OuagadougouBurkina Faso

Objective:To evaluate efficiency of HAART in the prevention of mother to child HIV ***:A longitudinal study was conducted on 1 300 women attending the antenatal service at Saint Camille Medical Centre from September 2010 to July *** HIV status of mothers was determined by rapid tests and *** results were confirmed by real-time *** was used to determine HIV status of children born from HIV-positive ***:Among 1 300 pregnant women tested for HIV,378 were *** were predominantly housewives(69.7%),and their mean age was(28.32±0.15) *** overall prevalence of HIV transmission from mother to child was 4.8%(18/378).This prevalence differed significantly from 0.0%(0/114) to 6.8%(18/264) in children born from mothers under HAART and those with mothers under New Prophylactic Protocol(ACT + 3TC + NVP),respectively(P< 0.01).Children’s mortality rate during the medical follow up was 1.3%(5/378).Among 16 women with HIV dubious status by ELISA,the Real Time PCR confirmed 2/16(12.5%) as HIV positive. Conclusions:The protocol of prevention of mother to children HIV transmission(PMTCT) is *** rate of HIV vertical transmission is significantly *** diagnosis determined by PCR of children born from HIV- positive mother is necessary and recommended in the context of PMTCT in Burkina *** also found that PCR is an effective tool to confirm HIV status in pregnant women.

关键词： Pregnant Women Child HIV PCR DNA

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Diagnostic Performance of Five Rapid Serological Tests for SARS-CoV-2

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Open Journal of Epidemiology（流行病学期刊） 2022年第4期

作者： Gilbert Ndziessi Jospeh Axel Ngatse Fabien Roch Niama Henriette Poaty Mayengue Pembe Issamou Fresnovie Geladore Mbele laure stella ghoma linguissi Francine Ntoumi

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