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Elastocaloric effect and mechanical behavior for NiTi shape memory alloys

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Chinese Physics B 2018年第10期27卷 518-524页

作者： Min Zhou Yu-shuang li Chen Zhang Lai-Feng li Key Laboratory of Cryogenics Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190China School of Materials Science and Engineering Beihang UniversityBeijing 100191China

The NiTi shape memory alloy exhibits excellent superelastic property and elastocaloric effect. The large temperature change（DT） value of 30 K upon loading and-19 K upon unloading are obtained at room temperature, which are higher than those of the other NiTi-based materials and among the highest values reported in the elastocaloric materials. The asymmetry of the measured DT values between the loading and unloading process is ascribed to the friction *** large temperature change originates from the large entropy change during the stress-induced martensite transformation（MT） and the reverse MT. A large coefficient-of-performance of the material is obtained to be 11.7 at ε= 1%, which decreases with increasing the applied strain. These results are very attractive in the present solid-state cooling, which potentially could replace the vapor compression refrigeration technologies.

关键词： elastocaloric effect shape memory alloy martensitic transformation entropy change

Isolation, purification and structural characterization of a water-soluble polysaccharide HM41 from Halenia elliptica ***

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Chinese Chemical Letters 2016年第6期27卷 979-983页

作者： Chun-Lan liu Yang li Gui-Yun Xu Ya-shuang li College of life and Environmental Science Minzu University of ChinaBeijing 100081China Beijing Engineering Research Center of Food Environment and Public Health Minzu University of ChinaBeijing 100081China Institute of Chemistry Chinese Academy of SciencesBeijing 100080China

A water-soluble polysaccharide, HM（41）, was obtained from Halenia elliptica D. Don by acidic ethanol fractionation and gel filtration. Its homogeneity was confirmed by chromatography using multiple systems. HM（41） was composed of rhamnose（Rha）, arabinose（Ara）, xylose（Xyl）, mannose（Man）,galactose（Gal）, glucose（Glc） with a molar ratio of 1.0：5.5：1.8：3.0：9.4：21. The average molecular weight of HM（41） was approximately 1.17 ＊ 10~4. Periodate oxidation, Smith degradation, methylation and GC, IR,NMR, XRD, GC–MS analysis were used for the structural analysis of HM（41）. Its main chain was composed mainly of β-（1→4）Gal, β-（1→4）Glc and β-（1→6）Glc. β-（1 →4）Gal were substituted at 6-O and on average there were 14 branches among 23 main chain residues;（1→ 4）Glc had no branch;（1→6）Glc were substituted at 3-O and on average there were 9 branches among 14 main chain residues. The side chain was composed of（1→3,6）-Rha,（1→4）/（1→5）-Ara,（1 →4）/（1→5）-Xyl,（1→4,6）-Man and（1→2）-Glc. The terminal residue was composed of Ara, Xyl, Man, Gal, and Glc. Then, we demonstrated that HM and HM（41） had strong scavenging activities in vitro hydroxyl. Overall, HM and HM（41） may have potential applications in the antioxidants for medical and food industry.

关键词： Halenia elliptica D.Don Polysaccharide Isolation purification Structural analysis Antioxidant activities

Review of Trajectory Design and Optimization for Jovian System Exploration

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Space(Science & Technology) 2023年第1期3卷 279-292页

作者： Hongwei Yang Jincheng Hu Xiaoli Bai shuang li College of Astronautics Nanjing University of Aeronautics and AstronauticsNanjing 211106China Rutgers The State University of New JerseyPiscatawayNJ 08854USA

Jupiter exploration is one of the focuses of deep space exploration in the near *** and optimization of trajectories in the Jovian system are crucial technologies for Jupiter exploration missions due to the unique and challenging multi-body dynamical *** methodologies have been proposed and ***,there is a lack of comprehensive review of these methodologies,which is unfavorable for further developing new design techniques and proposing new mission *** review provides a systematic summarization of the past and state-of-art methodologies for 4 main exploration phases,including Jupiter capture,the tour of the Galilean moons,Jupiter global mapping,and orbiting around and landing on a target *** each exploration phase,the related methods are categorized according to the fundamental *** advantages and capabilities of the methods are described or analyzed,revealing the research ***,a prospect of future development of the methods is presented,aiming at providing references for further studies on trajectory design and optimization in the Jovian system.

关键词： Jupiter exploration revealing

Detrital zircon U-Pb age perspective on the sediment provenance and its geological significance of sandstones in the Lamandau region, SW Borneo, Indonesia

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Journal of Oceanology and limnology 2022年第2期40卷 496-514页

作者： shuang li Saijun SUN Xiaoyong YANG Weidong SUN Zhaojian WU Guangxi Key Laboratory of Hidden Metallic Ore Deposits Exploration College of Earth SciencesGuilin University of TechnologyGuilin 541004China Center of Deep Sea Research Institute of OceanologyCenter for Ocean Mega-ScienceChinese Academy of SciencesQingdao 266071China Laboratory for Marine Geology Pilot National Laboratory for Marine Science and Technology(Qingdao)Qingdao 266237China CAS Key Laboratory of Crust-Mantle Materials and Environments School of Earth and Space SciencesUniversity of Science and Technology of ChinaHefei 230026China China Coal Geology Group limited Beijing 100040China

The Southwest Borneo(SW Borneo)block belongs to Sundaland and is the oldest continental fragment of Borneo that is believed to derive from the Gondwana *** U-Pb isotopic dating ages of 113 detrital zircons from sandstones of the Ketapang Complex in SW Borneo range from 3298 Ma to 78 Ma,and show six major age populations:2476-2344 Ma,2016-1831 Ma,1296-759 Ma,455-406 Ma,262-210 Ma,and 187-78 *** youngest age of these detrital zircons is 78 Ma,indicating that the maximum depositional age of the sandstones is ***-Late Cretaceous detrital zircons are interpreted as having been derived from the nearby Schwaner Mountains and the Permian-Triassic tin belt granitoids in Southeast Asia(SE Asia).Archean-Carboniferous detrital zircons have a continental Gondwana provenance,with their age spectra similar to those of northwestern Australia,indicating that these zircons could be derived from the orogenic belts and cratons in northwestern and central *** provenance of these detrital zircons in this study indicates the SW Borneo block was located on the northwestern margin of Australia during the Paleozoic,in the region of the Banda *** Borneo rifted from Australia and moved northward in the Early Jurassic,and this block was added to Sundaland in the Early *** Luconia-Dangerous Grounds continental fragment derived from East Asia collided with SW Borneo after subduction in the Cretaceous,which induced the widespread magmatism in the Schwaner Mountains in SW Borneo.

关键词： detrital zircon U-Pb dating provenance Southwest Borneo(SW Borneo) Sundaland

Antibody-activated trans-endothelial delivery of mesoporous organosilica nanomedicine augments tumor extravasation and anti-cancer immunotherapy

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Bioactive Materials 2021年第7期6卷 2158-2172页

作者： Tinglei Huang shuang li Jianchen Fang Fuli li Shuiping Tu Department of Oncology State Key Laboratory of Oncogenes and Related GenesRenji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai200127China Department of Stomatology Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai200127China Department of Pathology Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai200127China

Tumor vasculature constitutes a formidable hurdle for the efficient delivery of cancer nanomedicine into *** leverage of passive pathway through inter-endothelial gaps in tumor blood vessels might account for limited extravasation of nanomedicine into tumor microenvironment(TME).Herein,Annexin A1 antibody-installed mesoporous organosilica nanoplatforms carrying immunotherapeutics of anti-PD-L1 antibody(aPD-L1)and Indoximod are developed to target at caveolar Annexin-A1 protein of luminal endothelial cells and to trigger the active trans-endothelial transcytosis of nanomedicine mediated by *** strategy enables rapid nanomedicine extravasation across tumor endothelium and relatively extensive accumulation in tumor ***-L1 and Indoximod release from aPD/IND@MON-aANN in a reduction-responsive manner and synergistically facilitate the intratumoral infiltration of cytotoxic T lymphocytes and reverse the immunosuppressive TME,thus demonstrating substantial anti-tumor efficacy in subcutaneous 4T1 breast tumors and remarkable anti-metastatic capacity to extend the survival of 4T1 tumor metastasis ***,aPD/IND@MON-aANN nanomedicine also exhibits distinct superiority over the combination therapy of free drugs to potently attenuate the progression of urethane-induced orthotopic lung ***,aPD/IND@MON-aANN nanoplatforms with boosted delivery efficiency via antibody-activated trans-endothelial pathway and enhanced immunotherapeutic efficacy provides perspectives for the development of cancer nanomedicines.

关键词： Active transcytosis Extravasation Drug delivery Cancer immunotherapy Stimulus-responsive nanomedicine

Overview of China’s 2020 Mars mission design and navigation

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Astrodynamics 2018年第1期2卷 1-11页

作者： Xiuqiang Jiang Bin Yang shuang li Department of Astronautics Engineering College of AstronauticsNanjing University of Aeronautics and AstronauticsNanjing210016China Space New Technology Laboratory Nanjing University of Aeronautics and AstronauticsNanjing210016China

Scheduled for an Earth-to-Mars launch opportunity in 2020,the China’s Mars probe will arrive on Mars in 2021 with the primary objective of injecting an orbiter and placing a lander and a rover on the surface of the Red *** China’s 2020 Mars exploration mission to achieve success,many key technologies must be *** this paper,China’s 2020 Mars mission and the spacecraft architecture are first ***,the preliminary launch opportunity,Earth–Mars transfer,Mars capture,and mission orbits are ***,the main navigation schemes are summarized.

关键词： China’s Mars exploration mission orbiting,landing,and roaming orbit design navigation scheme

Plasma jet array treatment to improve the hydrophobicity of contaminated HTV silicone rubber

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Plasma Science and Technology 2017年第10期19卷 75-82页

作者： Ruobing ZHANG Qianting HAN Yan XIA shuang li Laboratory of Advanced Technology of Electrical Engineering and Energy Graduate School at Shenzhen Tsinghua University Shenzhen 518055 People＇s Republic of China

An atmospheric-pressure plasma jet array specially designed for HTV silicone rubber treatment is reported in this paper. Stable plasma containing highly energetic active particles was uniformly generated in the plasma jet array. The discharge pattern was affected by the applied voltage. The divergence phenomenon was observed at low gas flow rate and abated when the flow rate *** of the plasma plume is close to room temperature which makes it feasible for temperature-sensitive material treatment. Hydrophobicity of contaminated HTV silicone rubber was significantly improved after quick exposure of the plasma jet array, and the effective treatment area reached 120 mm？×？50 mm（length？×？width）. Reactive particles in the plasma accelerate accumulation of the hydrophobic molecules, namely low molecular weight silicone chains, on the contaminated surface, which result in a hydrophobicity improvement of the HTV silicone rubber.

关键词： atmospheric-pressure plasma jet plasma jet array hydrophobicity HTV silicone rubber

MicroRNA-320a suppresses tumor progression by targeting PBX3 in gastric cancer and is downregulated by DNA methylation

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World Journal of Gastrointestinal Oncology 2019年第10期11卷 842-856页

作者： Yong-shuang li Ying Zou Dong-Qiu Dai Department of Gastrointestinal Surgery the Fourth Affiliated Hospital of China Medical University

BACKGROUND Ectopic expression of miRNAs promotes tumor development and ***(miR)-320a is downregulated in many cancers,including gastric cancer(GC).However,the mechanism underlying its downregulation and the role of miR-320a in GC are *** To determine expression and biological functions of miR-320a in GC and investigate the underlying molecular *** Quantitative real-time polymerase chain reaction(PCR)was used to determine expression of miR-320a in GC cell lines and ***7.1,miRDB,and *** were used to predict the possible targets of miR-320a,and a dual luciferase assay was used to confirm the *** blotting was used to detect the protein levels of pre-B-cell leukemia homeobox 3(PBX3)in GC cells and tissue *** Counting Kit-8 proliferation,Transwell,wound healing,and apoptosis assays were performed to analyze the biological functions of miR-320a in GC ***-specific PCR was used to analyze the methylation level of the miR-320a promoter CpG islands.5-Aza-2’-deoxycytidine(5-Aza-CdR)and trichostatin A(TSA)were used to treat GC *** miR-320a expression was lower in GC cell lines and tissues than in the normal gastric mucosa cell line GES-1 and matched adjacent normal ***-320a overexpression suppressed GC cell proliferation,invasion and migration,and induced ***3 was a target of miR-320a in *** methylation level of the miR-320a promoter CpG islands was elevated and this was partly reversed by 5-Aza-CdR and *** miR-320a acts as a tumor suppressor and inhibits malignant behavior of GC cells,partly by targeting *** methylation is an important mechanism associated with low expression of miR-320a.

关键词： Gastric cancer miRNA-320a DNA methylation Pre-B-cell leukemia homeobox 3 Tumor suppressor

Remarkable Thermal Contraction in Small Size Single-Walled Boron Nanotubes

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Communications in Computational Physics 2014年第6期16卷 201-212页

作者： Xianhu Zha shuang li Ruiqin Zhang Zijing lin Department of Physics&Collaborative Innovation Center of Suzhou Nano Science and Technology University of Science and Technology of ChinaHefei 230026China. Department of Physics and Materials Science City University of Hong KongKowloon TongHong Kong. USTC-CityU Joint Advanced Research Centre Suzhou 215123China. Nano Structured Materials Center Nanjing University of Science and TechnologyNanjing 210094China.

Density functional theory combined with the Gr¨uneisen approximation is used to calculate the thermal properties of single-walled boron nanotubes(BNTs).The specific heat and thermal expansion are *** thermal expansion coeffi-cient of the BNT is found to be significantly correlated with tube size and chirality.A remarkable thermal contraction is found at small tube *** results indicate that BNTs would have potential applications in sensors,actuators,and memory materials.

关键词： Density functional theory Gruneisen approximation single-walled boron nanotubes remarkable thermal contraction.