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Pro-resolving lipid mediator reduces amyloid-β42–induced gene expression in human monocyte–derived microglia

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Neural Regeneration Research 2025年第3期20卷 873-886页

作者： Ying Wang Xiang Zhang Henrik Biverstål Nicolas GBazan Shuai Tan Nailin li Makiko Ohshima Marianne Schultzberg Xiaofei li Department of Neurobiology Care Sciences&SocietyDivision of NeurogeriatricsKarolinska InstitutetStockholmSweden Department of Neurology Neuroscience CenterThe First Hospital of Jilin UniversityChangchunJilin ProvinceChina Department of Physiology and Pharmacology Karolinska InstitutetStockholmSweden Department of Biosciences and Nutrition Karolinska InstitutetHuddingeSweden Neuroscience Center of Excellence Louisiana State UniversityNew OrleansLAUSA Department of Medicine SolnaClinical Pharmacology GroupKarolinska University HospitalStockholmSweden

Specialized pro-resolving lipid mediators including maresin 1 mediate resolution but the levels of these are reduced in Alzheimer's disease brain, suggesting that they constitute a novel target for the treatment of Alzheimer's disease to prevent/stop inflammation and combat disease pathology. Therefore, it is important to clarify whether they counteract the expression of genes and proteins induced by amyloid-β. With this objective, we analyzed the relevance of human monocyte–derived microglia for in vitro modeling of neuroinflammation and its resolution in the context of Alzheimer's disease and investigated the pro-resolving bioactivity of maresin 1 on amyloid-β42–induced Alzheimer's disease–like inflammation. Analysis of RNA-sequencing data and secreted proteins in supernatants from the monocyte-derived microglia showed that the monocyte-derived microglia resembled Alzheimer's disease–like neuroinflammation in human brain microglia after incubation with amyloid-β42. Maresin 1 restored homeostasis by down-regulating inflammatory pathway related gene expression induced by amyloid-β42 in monocyte-derived microglia, protection of maresin 1 against the effects of amyloid-β42 is mediated by a re-balancing of inflammatory transcriptional networks in which modulation of gene transcription in the nuclear factor-kappa B pathway plays a major part. We pinpointed molecular targets that are associated with both neuroinflammation in Alzheimer's disease and therapeutic targets by maresin 1. In conclusion, monocyte-derived microglia represent a relevant in vitro microglial model for studies on Alzheimer's disease-like inflammation and drug response for individual patients. Maresin 1 ameliorates amyloid-β42–induced changes in several genes of importance in Alzheimer's disease, highlighting its potential as a therapeutic target for Alzheimer's disease.

关键词： Alzheimer's disease amyloid-β maresin microglia monocyte neuroinflammation resolution RNA-sequencing specialized pro-resolving lipid mediator

Study of BESIII trigger efficiencies with the 2018 J/ψ data

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Chinese Physics C 2021年第2期45卷 48-55页

作者： M.Ablikim M.N.Achasov P.Adlarson S.Ahmed M.Albrecht R.Aliberti A.Amoroso M.R.An Q.An X.H.Bai Y.Bai O.Bakina R.Baldini Ferroli I.Balossino Y.Ban k.Begzsuren N.Berger M.Bertani D.Bettoni F.Bianchi J.Bloms A.Bortone I.Boyko R.A.Briere H.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.F.Chang W.l.Chang G.Chelkov D.Y.Chen G.Chen H.S.Chen M.l.Chen S.J.Chen X.R.Chen Y.B.Chen Z.J Chen W.S.Cheng G.Cibinetto F.Cossio X.F.Cui H.l.Dai X.C.Dai A.Dbeyssi R.E.de Boer D.Dedovich Z.Y.Deng A.Denig I.Denysenko M.Destefanis F.De Mori Y.Ding C.Dong J.Dong l.Y.Dong M.Y.Dong X.Dong S.X.Du Y.l.Fan J.Fang S.S.Fang Y.Fang R.Farinelli l.Fava F.Feldbauer G.Felici C.Q.Feng J.H.Feng M.Fritsch C.D.Fu Y.Gao Y.Gao Y.Gao Y.G.Gao I.Garzia P.T.Ge C.Geng E.M.Gersabeck A Gilman k.Goetzen l.Gong W.X.Gong W.Gradl M.Greco l.M.Gu M.H.Gu S.Gu Y.T.Gu C.Y Guan A.Q.Guo l.B.Guo R.P.Guo Y.P.Guo A.Guskov T.T.Han W.Y.Han X.Q.Hao F.A.Harris H Hüsken k.l.He F.H.Heinsius C.H.Heinz T.Held Y.k.Heng C.Herold M.Himmelreich T.Holtmann Y.R.Hou Z.l.Hou H.M.Hu J.F.Hu T.Hu Y.Hu G.S.Huang l.Q.Huang X.T.Huang Y.P.Huang Z.Huang T.Hussain W.Ikegami Andersson W.Imoehl M.Irshad S.Jaeger S.Janchiv Q.Ji Q.P.Ji X.B.Ji X.l.Ji H.B.Jiang X.S.Jiang J.B.Jiao Z.Jiao S.Jin Y.Jin T.Johansson N.kalantar-Nayestanaki X.S.kang R.kappert M.kavatsyuk B.C.ke I.k.keshk A.khoukaz P.kiese R.kiuchi R.kliemt l.koch O.B.kolcu B.kopf M.kuemmel M.kuessner A.kupsc M.G.kurth W.kühn J.J.lane J.S.lange P.larin A.lavania l.lavezzi Z.H.lei H.leithoff M.lellmann T.lenz C.li C.H.li Cheng li D.M.li F.li G.li H.li H.li H.B.li H.J.li J.l.li J.Q.li J.S.li ke li l.k.li lei li P.R.li S.Y.li W.D.li W.G.li X.H.li X.l.li Z.Y.li H.liang H.liang H.liang Y.F.liang Y.T.liang l.Z.liao J.libby C.X.lin B.J.liu C.X.liu D.liu F.H.liu Fang liu Feng liu H.B.liu H.M.liu Huanhuan liu Huihui liu J.B.liu J.l.liu J.Y.liu k.liu k.Y.liu ke liu l.liu M.H.liu P.l.liu Q.liu Q.liu S.B.liu Shuai liu T.liu W.M.liu X.liu Y.liu Y.B.liu Z.A.liu Z.Q.liu X.C.lou F.X.lu H.J.lu J.D.lu J.G.lu X.l.lu Y.lu Y.P.lu C.l.luo M.X.luo b P.W.luo T.luo X.l.luo S Institute of High Energy Physics Beijing 100049China Beihang University Beijing 100191China Beijing Institute of Petrochemical Technology Beijing 102617China Bochum Ruhr-University D-44780 BochumGermany Carnegie Mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China China Center of Advanced Science and Technology Beijing 100190China COMSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200443China GIBudker Institute of Nuclear Physics SB RAS(BINP) Novosibirsk 630090Russia GSI Helmholtzcentre for Heavy Ion Research GmbH D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China Hangzhou Normal University Hangzhou 310036China Helmholtz Institute Mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University of Science and Technology Luoyang 471003China Huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA (A)INFN laboratori Nazionali di Frascati I-00044FrascatiItaly(B)INFN Sezione di PerugiaI-06100PerugiaItaly(C)University of PerugiaI-06100PerugiaItaly (A)INFN Sezione di Ferrara I-44122FerraraItaly(B)University of FerraraI-44122FerraraItaly Institute of Modern Physics Lanzhou 730000China Institute of Physics and Technology Peace Ave54BUlaanbaatar 13330Mongolia Jilin University Changchun 130012China Johannes Gutenberg University of Mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany Joint Institute for Nuclear Research 141980 DubnaMoscow regionRussia Justus-liebig-Universitaet Giessen IIPhysikalisches InstitutHeinrich-Buff-Ring 16D-35392GiessenGermany kVI-CART University of GroningenNL-9747 AA GroningenThe Netherlands lanzhou University Lanzhou 730000China liaoning Normal Unive

Using a dedicated data sample taken in 2018 on the J/ψpeak,we perform a detailed study of the trigger efficiencies of the BESIII *** efficiencies are determined from three representative physics processes,namely Bhabha scattering,dimuon production and generic hadronic events with charged *** combined efficiency of all active triggers approaches 100%in most cases,with uncertainties small enough not to affect most physics analyses.

关键词： BESIII trigger efficiency Bhabha dimuon hadronic events

Future Physics Programme of BESⅢ

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Chinese Physics C 2020年第4期44卷 I0001-I0004,1-102页

作者： M.Ablikim M.N.Achasov P.Adlarson S.Ahmed M.Albrecht M.Alekseev A.Amoroso F.F.An Q.An Y.Bai O.Bakina R.Baldini Ferroli Y.Ban k.Begzsuren J.V.Bennett N.Berger M.Bertani D.Bettoni F.Bianchi J Biernat J.Bloms I.Boyko R.A.Briere l.Calibbi H.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.Chai J.F.Chang W.l.Chang J.Charles G.Chelkov Chen G.Chen H.S.Chen J.C.Chen M.l.Chen S.J.Chen Y.B.Chen H.Y.Cheng W.Cheng G.Cibinetto F.Cossio X.F.Cui H.l.Dai J.P.Dai X.C.Dai A.Dbeyssi D.Dedovich Z.Y.Deng A.Denig Denysenko M.Destefanis S.Descotes-Genon F.De Mori Y.Ding C.Dong J.Dong l.Y.Dong M.Y.Dong Z.l.Dou S.X.Du S.I.Eidelman J.Z.Fan J.Fang S.S.Fang Y.Fang R.Farinelli l.Fava F.Feldbauer G.Felici C.Q.Feng M.Fritsch C.D.Fu Y.Fu Q.Gao X.l.Gao Y.Gao Y.Gao Y.G.Gao Z.Gao B.Garillon I.Garzia E.M.Gersabeck A.Gilman k.Goetzen l.Gong W.X.Gong W.Gradl M.Greco l.M.Gu M.H.Gu Y.T.Gu A.Q.Guo F.k.Guo l.B.Guo R.P.Guo Y.P.Guo A.Guskov S.Han X.Q.Hao F.A.Harris k.l.He F.H.Heinsius T.Held Y.k.Heng Y.R.Hou Z.l.Hou H.M.Hu J.F.Hu T.Hu Y.Hu G.S.Huang J.S.Huang X.T.Huang X.Z.Huang Z.l.Huang N.Huesken T.Hussain W.Ikegami Andersson W.Imoehl M.Irshad Q.Ji Q.P.Ji X.B.Ji X.l.Ji H.l.Jiang X.S.Jiang X.Y.Jiang J.B.Jiao Z.Jiao D.P.Jin S.Jin Y.Jin T.Johansson N.kalantar-Nayestanaki X.S.kang R.kappert M.kavatsyuk B.C.ke I.k.keshk T.khan A.khoukaz P.kiese R.kiuchi R.kliemt l.koch O.B.kolcu B.kopf M.kuemmel M.kuessner A.kupsc M.kurth M.G.kurth W.kuhn J.S.lange P.larin l.lavezzi H.leithoff T.lenz C.li Cheng li D.M.li F.li F.Y.li G.li H.B.li H.J.li J.C.li J.W.li ke li l.k.li lei li P.l.li P.R.li Q.Y.li W.D.li W.G.li X.H.li X.l.li X.N.li X.Q.li Z.B.li H.liang H.liang Y.F.liang Y.T.liang G.R.liao l.Z.liao J.libby C.X.lin D.X.lin Y.J.lin B.liu B.J.liu C.X.liu D.liu D.Y.liu F.H.liu Fang liu Feng liu H.B.liu H.M.liu Huanhuan liu Huihui liu J.B.liu J.Y.liu k.Y.liu ke liu Q.liu S.B.liu T.liu X.liu X.Y.liu Y.B.liu Z.A.liu Zhiqing liu Y.F.long X.C.lou H.J.lu J.D.lu J.G.lu Y.lu Y.P.lu C.l.luo M.X.luo P.W.luo T.luo X.l.luo S.lusso X.R.lyu F.C.Ma H.l.Ma l.l.Ma M.M.Ma Q.M.Ma X.N.Ma X.X. Institute of High Energy Physics Beijing 100049China Beihang University Beijing 100191China Beijing Institute of Petrochemical Technology Beijing 102617China Bochum Ruhr-University D-44780 BochumGermany Carnegie Mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China China Center of Advanced Science and Technology Beijing 100190China COMSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200443China G.I.Budker Institute of Nuclear Physics SB RAS(BINP) Novosibirsk 630090Russia GSI Helmholtzcentre for Heavy Ion Research GmbH D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China Hangzhou Normal University Hangzhou 310036China Helmholtz Institute Mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University of Science and Technology Luoyang 471003China Huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN laboratori Nazionali di Frascati I-00044FrascatiItaly INFN Sezione di Ferrara I-44122FerraraItaly Institute of Physics and Technology Peace Ave.54BUlaanbaatar 13330Mongolia Johannes Gutenberg University of Mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany Joint Institute for Nuclear Research 141980 DubnaMoscow regionRussia Justus-liebig-Universitaet Giessen II.Physikalisches InstitutHeinrich-Buff-Ring 16D-35392 GiessenGermany kVI-CART University of GroningenNL-9747 AA GroningenThe Netherlands lanzhou University Lanzhou 730000China liaoning University Shenyang 110036China Nanjing Normal University Nanjing 210023China Nanjing University Nanjing 210093China Nankai University Tianjin 300071China Peking University Beijing 100871China Shandong University Jinan 250100China Shanghai

There has recently been a dramatic renewal of interest in hadron spectroscopy and charm physics. This renaissance has been driven in part by the discovery of a plethora of charmonium-like XYZ states at BESⅢ and B factories, and the observation of an intriguing proton-antiproton threshold enhancement and the possibly related X(1835) meson state at BESⅢ, as well as the threshold measurements of charm mesons and charm baryons. We present a detailed survey of the important topics in tau-charm physics and hadron physics that can be further explored at BESⅢ during the remaining operation period of BEPCⅡ. This survey will help in the optimization of the data-taking plan over the coming years, and provides physics motivation for the possible upgrade of BEPCⅡ to higher luminosity.

关键词： meson hadron optimization

Measurements of the center-of-mass energies of e^(+)e^(-)collisions at BESIII

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Chinese Physics C 2021年第10期45卷 7-15页

作者： M.Ablikim M.N.Achasov P.Adlarson S.Ahmed M.Albrecht R.Aliberti A.Amoroso M.R.An Q.An X.H.Bai Y.Bai O.Bakina R.Baldini Ferroli I.Balossino Y.Ban k.Begzsuren N.Berger M.Bertani D.Bettoni F.Bianchi J.Bloms A.Bortone I.Boyko R.A.Briere H.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.F.Chang W.l.Chang G.Chelkov D.Y.Chen G.Chen H.S.Chen M.l.Chen S.J.Chen X.R.Chen Y.B.Chen Z.J.Chen W.S.Cheng G.Cibinetto F.Cossio X.F.Cui H.l.Dai X.C.Dai A.Dbeyssi R.E.de Boer D.Dedovich Z.Y.Deng A.Denig I.Denysenko M.Destefanis F.De Mori Y.Ding C.Dong J.Dong l.Y.Dong M.Y.Dong X.Dong S.X.Du Y.l.Fan J.Fang S.S.Fang Y.Fang R.Farinelli l.Fava F.Feldbauer G.Felici C.Q.Feng J.H.Feng M.Fritsch C.D.Fu Y.Gao Y.Gao Y.Gao Y.G.Gao I.Garzia P.T.Ge C.Geng E.M.Gersabeck A Gilman k.Goetzen l.Gong W.X.Gong W.Gradl M.Greco l.M.Gu M.H.Gu Y.T.Gu C.Y Guan A.Q.Guo l.B.Guo R.P.Guo Y.P.Guo A.Guskov T.T.Han W.Y.Han X.Q.Hao F.A.Harris k.l.He F.H.Heinsius C.H.Heinz T.Held Y.k.Heng C.Herold M.Himmelreich T.Holtmann G.Y.Hou Y.R.Hou Z.l.Hou H.M.Hu J.F.Hu T.Hu Y.Hu G.S.Huang l.Q.Huang X.T.Huang Y.P.Huang Z.Huang T.Hussain N Husken W.Ikegami Andersson W.Imoehl M.Irshad S.Jaeger S.Janchiv Q.Ji Q.P.Ji X.B.Ji X.l.Ji Y.Y.Ji H.B.Jiang X.S.Jiang J.B.Jiao Z.Jiao S.Jin Y.Jin M.Q.Jing T.Johansson N.kalantar-Nayestanaki X.S.kang R.kappert M.kavatsyuk B.C.ke I.k.keshk A.khoukaz P.kiese R.kiuchi R.kliemt l.koch O.B.kolcu B.kopf M.kuemmel M.kuessner A.kupsc M.G.kurth W.kuhn J.J.lane J.S.lange P.larin A.lavania l.lavezzi Z.H.lei H.leithoff M.lellmann T.lenz C.li C.H.li Cheng li D.M.li F.li G.li H.li H.li H.B.li H.J.li J.l.li J.Q.li J.S.li ke li l.k.li lei li P.R.li S.Y.li W.D.li W.G.li X.H.li X.l.li Xiaoyu li Z.Y.li H.liang H.liang H.liang Y.F.liang Y.T.liang G.R.liao l. Z. liao J.libby C.X.lin B.J.liu C.X.liu D.liu F.H.liu Fang liu Feng liu H.B.liu H.M.liu Huanhuan liu Huihui liu J.B.liu J.l.liu J.Y.liu k.liu k.Y.liu l.liu M.H.liu P.l.liu Q.liu Q.liu S.B.liu Shuai liu T.liu W.M.liu X.liu Y.liu Y.B.liu Z.A.liu Z.Q.liu X.C.lou F.X.lu H.J.lu J.D.lu J.G.lu X.l.lu Y.lu Y.P.lu C.l.luo Institute of High Energy Physics Beijing 100049China Beihang University Beijing 100191China Beijing Institute of Petrochemical Technology Beijing 102617China Bochum Ruhr-University D-44780 BochumGermany Carnegie Mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China China Center of Advanced Science and Technology Beijing 100190China COMSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200443China G.I.Budker Institute of Nuclear Physics SB RAS(BINP) Novosibirsk 630090Russia GSI Helmholtzcentre for Heavy Ion Research GmbH D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China Hangzhou Normal University Hangzhou 310036China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University of Science and Technology Luoyang 471003China Huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN laboratori Nazionali di Frascati INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly INFN laboratori Nazionali di Frascati INFN Sezione di PerugiaI-06100PerugiaItaly INFN laboratori Nazionali di Frascati University of PerugiaI-06100PerugiaItaly INFN Sezione di Ferrara INFN Sezione di FerraraI-44122FerraraItaly INFN Sezione di Ferrara University of FerraraI-44122FerraraItaly 25Institute of Modern PhysicsLanzhou 730000China Institute of Modern Physics Lanzhou 730000China Institute of Physics and Technology Peace Ave.54BUlaanbaatar 13330Mongolia Jilin University Changchun 130012China Johannes Gutenberg University of Mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany Joint Institute for Nuclear Research 141980 DubnaMoscow regionRussia Justus-liebig-Universitaet Giessen II.Physikali

During the 2016-17 and 2018-19 running periods,the BESIII experiment collected 7.5 fb of e^(+)e^(-)collision data at center-of-mass energies ranging from 4.13 to 4.44 *** data samples are primarily used for the study of excited charmonium and charmoniumlike *** analyzing the di-muon process e^(+)e^(-)→(γISR=FSR)μ^(+)μ^(-),we measure the center-of-mass energies of the data samples with a precision of 0.6 *** a run-by-run study,we find that the center-of-mass energies were stable throughout most of the data-collection period.

关键词： center-of-mass energy e^(+)e^(-) annihilation BESIII

Deciphering the role of mtH2O2 in hepatic ischemia-reperfusion injury mechanisms with low-background super-resolution fluorogenic probe

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Science China Chemistry 2025年第1期68卷 297-307页

作者： Bin Fang limin Wang Haoqin li Jiaxin Zhang Yang Ding Pan Pan li Bo Peng Hua Bai lin li Frontiers Science Center for Flexible Electronics Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials &Engineering Northwestern Polytechnical University Institute of Flexible Electronics (IFE Future Technologies) Xiamen University

Hepatic ischemia-reperfusion injury（HIRI） is characterized by mitochondrial dysfunction and oxidative stress. Monitoring mitochondrial hydrogen peroxide（mtH2O2） levels in real-time through super-resolution imaging is crucial for elucidating its distribution in live cells and its mechanism of action during HIRI. However, low-background fluorogenic probes have been overlooked in the context of super-resolution imaging. In this study, we developed a low-background fluorogenic probe（MitoWG） with the potential for super-resolution morphology-correlated mitochondrial identification to track the fluctuates of mtH2O2in HIRI. Activation of the desirable fluorescence properties of the probe by mtH2O2was confirmed using structural illumination microscopy（SIM）, enabling high-quality mitochondrial imaging with exceptional specificity and *** in mtH2O2levels were successfully observed in both cellular and rat models of HIRI. Furthermore, we associated the decline in mitochondrial redox homeostasis with accelerated mtH2O2production during HIRI, which triggered mitophagy deficiency and led to cell death. In conclusion, Mito-WG possesses excellent photophysical and low-background properties for SIM imaging, making it a promising tool for mtH2O2tracking in HIRI research and clinical diagnosis.

关键词： hepatic ischemia-reperfusion injury low-background mtH2O2-activatable super-resolution imaging fluorogenic probe

Amplitude analysis of the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)

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Chinese Physics C 2024年第8期48卷 6-33页

作者： M.Ablikim M.N.Achasov P.Adlarson O.Afedulidis X.C.Ai R.Aliberti A.Amoroso Q.An Y.Bai O.Bakina I.Balossino Y.Ban H.-R.Bao V.Batozskaya k.Begzsuren N.Berger M.Berlowski M.Bertani D.Bettoni F.Bianchi E.Bianco A.Bortone I.Boyko R.A.Briere A.Brueggemann H.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.F.Chang W.l.Chang G.R.Che G.Chelkov C.Chen C.H.Chen Chao Chen G.Chen H.S.Chen M.l.Chen S.J.Chen S.l.Chen S.M.Chen T.Chen X.R.Chen X.T.Chen Y.B.Chen Y.Q.Chen Z.J.Chen Z.Y.Chen S.k.Choi X.Chu G.Cibinetto F.Cossio J.J.Cui H.l.Dai J.P.Dai A.Dbeyssi R.E.de Boer D.Dedovich C.Q.Deng Z.Y.Deng A.Denig I.Denysenko M.Destefanis F.De Mori B.Fang S.S.Fang W.X.Fang Y.Fang Y.Q.Fang R.Farinelli l.Fava F.Feldbauer G.Felici C.Q.Feng J.H.Feng Y.T.Feng k.Fischer M.Fritsch C.D.Fu J.l.Fu Y.W.Fu H.Gao Y.N.Gao Yang Gao S.Garbolino I.Garzia P.T.Ge Z.W.Ge C.Geng E.M.Gersabeck B.Ding X.X.Ding Y.Ding Y.Ding J.Dong l.Y.Dong M.Y.Dong X.Dong M.C.Du S.X.Du Z.H.Duan P.Egorov Y.H.Fan J.Fang JA.Gilman k.Goetzen l.Gong W.X.Gong W.Gradl S.Gramigna M.Greco M.H.Gu Y.T.Gu C.Y.Guan Z.l.Guan A.Q.Guo l.B.Guo M.J.Guo R.P.Guo Y.P.Guo A.Guskov J.Gutierrez k.l.Han T.T.Han X.Q.Hao F.A.Harris k.k.He k.l.He F.H.Heinsius C.H.Heinz Y.k.Heng C.Herold T.Holtmann P.C.Hong G.Y.Hou X.T.Hou Y.R.Hou Z.l.Hou B.Y.Hu H.M.Hu J.F.Hu T.Hu Y.Hu G.S.Huang k.X.Huang l.Q.Huang X.T.Huang Y.P.Huang T.Hussain F.H\"olzken N.H\"usken N.in der Wiesche M.Irshad J.Jackson S.Janchiv J.H.Jeong Q.Ji Q.P.Ji W.Ji X.B.Ji X.l.Ji Y.Y.Ji X.Q.Jia Z.k.Jia D.Jiang H.B.Jiang P.C.Jiang S.S.Jiang T.J.Jiang X.S.Jiang Y.Jiang J.B.Jiao J.k.Jiao Z.Jiao S.Jin Y.Jin M.Q.Jing X.M.Jing T.Johansson S.kabana N.kalantar-Nayestanaki X.l.kang X.S.kang M.kavatsyuk B.C.ke V.khachatryan A.khoukaz R.kiuchi O.B.kolcu B.kopf M.kuessner X.kui A.kupsc W.k\"uhn J.J.lane P.larin l.lavezzi T.T.lei Z.H.lei H.leithoff M.lellmann T.lenz C.li C.li C.H.li Cheng li D.M.li F.li G.li H.li H.B.li H.J.li H.N.li Hui li J.R.li J.S.li k.li l.J.li l.k.li lei li M.H.li P.R.li Q.M.li Q.X.li R.li S.X.li T.li W.D.li W.G.li X.li X.H.li X.l.li X.Y.li Y Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Beihang University Beijing 100191China Bochum Ruhr-University D-44780 BochumGermany Budker Institute of Nuclear Physics SB RAS(BINP) Novosibirsk 630090Russia Carnegie Mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China Central South University Changsha 410083China China Center of Advanced Science and Technology Beijing 100190China China University of Geosciences Wuhan 430074China Chung-Ang University Seoul06974Republic of Korea COMSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200433China GSI Helmholtzcentre for Heavy Ion Research GmbH D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China Hangzhou Normal University Hangzhou 310036China Hebei University Baoding 071002China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China Henan University of Science and Technology Luoyang 471003China Henan University of Technology Zhengzhou 450001China Huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN laboratori Nazionali di Frascati INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly INFN laboratori Nazionali di Frascati INFN Sezione di PerugiaI-06100PerugiaItaly INFN laboratori Nazionali di Frascati University of PerugiaI-06100PerugiaItaly INFN Sezione di Ferrara INFN Sezione di FerraraI-44122FerraraItaly INFN Sezione di Ferrara University of FerraraI-44122FerraraItaly Inner Mongolia University Hohhot 010021China Institute of Modern Physics Lanzhou 730000China Institute of Physics and Technology Peace Avenue 54BUlaanbaatar 13330Mongolia Instituto de A

Using e^(+)e^(−)annihilation data corresponding to an integrated luminosity of 2.93 fb^(−1)taken at the center-of-mass energy√s=3.773 GeV with the BESIII detector,a joint amplitude analysis is performed on the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η).The fit fractions of individual components are obtained,and large interferences among the dominant components of the decays D^(0)→a_(1)(1260)π,D^(0)→π(1300)π,D^(0)→ρ(770)ρ(770),and D^(0)→2(ππ)_(S)are observed in both *** the obtained amplitude model,the CP-even fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are determined to be(75.2±1.1_(stat).±1.5_(syst.))%and(68.9±1.5_(stat).±2.4_(syst.))%,*** branching fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are measured to be(0.688±0.010_(stat.)±0.010_(syst.))%and(0.951±0.025_(stat.)±0.021_(syst.))%,*** amplitude analysis provides an important model for the binning strategy in measuring the strong phase parameters of D^(0)→4πwhen used to determine the CkM angleγ(ϕ_(3))via the B^(−)→Dk^(−)decay.

关键词： BESIII D^(0)meson decays amplitude analysis CP-even fraction

Observation of the Y(4230)and a new structure in e^(+)e^(-)→k^(+)k^(-)J/Ψ

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Chinese Physics C 2022年第11期46卷 7-21页

作者： M.Ablikim M.N.Achasov P.Adlarson M.Albrecht R.Aliberti A.Amoroso M.R.An Q.An X.H.Bai Y.Bai O.Bakina R.Baldini Ferroli I.Balossino Y.Ban V.Batozskaya D.Becker k.Begzsuren N.Berger M.Bertani D.Bettoni F.Bianchi J.Bloms A.Bortone I.Boyko R.A.Briere A.Brueggemann H.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.F.Chang W.l.Chang G.Chelkov C.Chen G.Chen H.S.Chen M.l.Chen S.J.Chen T.Chen X.R.Chen X.T.Chen Y.B.Chen Z.J.Chen W.S.Cheng X.Chu G.Cibinetto F.Cossio J.J.Cui H.l.Dai J.P.Dai A.Dbeyssi R.Ede Boer D.Dedovich Z.Y.Deng A.Denig I.Denysenko M.Destefanis F.De Mori Y.Ding J.Dong l.Y.Dong M.Y.Dong X.Dong S.X.Du P.Egorov Y.l.Fan J.Fang S.S.Fang W.X.Fang Y.Fang R.Farinelli l.Fava F.Feldbauer G.Felici C.Q.Feng J.H.Feng k Fischer M.Fritsch C.Fritzsch C.D.Fu H.Gao Y.N.Gao Yang Gao S.Garbolino I.Garzia P.T.Ge C.Geng E.M.Gersabeck A Gilman k.Goetzen l.Gong W.X.Gong W.Gradl M.Greco M.H.Gu C.Y Guan A.Q.Guo l.B.Guo R.P.Guo Y.P.Guo A.Guskov T.T.Han W.Y.Han X.Q.Hao F.A.Harris k.k.He k.l.He F.H.Heinsius C.H.Heinz Y.k.Heng C.Herold M.Himmelreich T.Holtmann G.Y.Hou Y.R.Hou Z.l.Hou H.M.Hu J.F.Hu T.Hu Y.Hu G.S.Huang k.X.Huang l.Q.Huang l.Q.Huang X.T.Huang Y.P.Huang Z.Huang T.Hussain N Husken W.Imoehl M.Irshad J.Jackson S.Jaeger S.Janchiv Q.Ji Q.P.Ji X.B.Ji X.l.Ji Y.Y.Ji Z.k.Jia H.B.Jiang S.S.Jiang X.S.Jiang Y.Jiang J.B.Jiao Z.Jiao S.Jin Y.Jin M.Q.Jing T.Johansson N.kalantar-Nayestanaki X.S.kang R.kappert M.kavatsyuk B.C.ke I.k.keshk A.khoukaz P.kiese R.kiuchi R.kliemt l.koch O.B.kolcu B.kopf M.kuemmel M.kuessner A.kupsc W.kuhn J.J.lane J.S.lange P.larin A.lavania l.lavezzi Z.H.lei H.leithoff M.lellmann T.lenz C.li C.li C.H.li Cheng li D.M.li F.li G.li H.li H.li H.B.li H.J.li H.N.li J.Q.li J.S.li J.W.li ke li l.J li l.k.li lei li M.H.li P.R.li S.X.li S.Y.li T.li W.D.li W.G.li X.H.li X.l.li Xiaoyu li Z.Y.li H.liang H.liang H.liang Y.F.liang Y.T.liang G.R.liao l.Z.liao J.libby A.limphirat C.X.lin D.X.lin T.lin B.J.liu C.X.liu D.liu F.H.liu Fang liu Feng liu G.M.liu H.liu H.M.liu Huanhuan liu Huihui liu J.B.liu J.l.liu J.Y.liu k.liu k.Y.l Institute of High Energy Physics Beijing 100049China Beihang University Beijing 100191China Beijing Institute of Petrochemical Technology Beijing 102617China Bochum Ruhr-University D-44780 BochumGermany Carnegie Mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China China Center of Advanced Science and Technology Beijing 100190China COMSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200433China G.I.Budker Institute of Nuclear Physics SB RAS(BINP) Novosibirsk 630090Russia GSI Helmholtzcentre for Heavy Ion Research GmbH D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Hangzhou Normal University Hangzhou 310036China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University of Science and Technology Luoyang 471003China Henan University of Technology Zhengzhou 450001China Huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN laboratori Nazionali di Frascati INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly INFN laboratori Nazionali di Frascati INFN Sezione di PerugiaI-06100PerugiaItaly INFN laboratori Nazionali di Frascati University of PerugiaI-06100PerugiaItaly INFN Sezione di Ferrara INFN Sezione di FerraraI-44122FerraraItaly INFN Sezione di Ferrara University of FerraraI-44122FerraraItaly Institute of Modern Physics Lanzhou 730000China Institute of Physics and Technology Peace Ave.54BUlaanbaatar 13330Mongolia Jilin University Changchun 130012China Johannes Gutenberg University of Mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany Joint Institute for Nuclear Research 141980 DubnaMoscow regionRussia Justus-liebig-Universitaet Giessen II.Physikalisches InstitutHeinrich-Buff-Ring 16

The cross sections of e^(+)e^(-)→k^(+)k^(-)J/Ψat center-of-mass energies from 4.127 to 4.600 GeV are measured based on 15.6 fb-1data collected with the BESⅢ detector operating at the BEPCⅡ storage *** resonant structures are observed in the line shape of the cross *** mass and width of the first structure are measured to be(4225.3±2.3±21.5)MeV and(72.9±6.1±30.8)MeV,*** are consistent with those of the established Y(4230).The second structure is observed for the first time with a statistical significance greater than 8σ,denoted as Y(4500).Its mass and width are determined to be(4484.7±13.3±24.1)MeV and(111.1±30.1±15.2)MeV,*** first presented uncertainties are statistical and the second ones are *** product of the electronic partial width with the decay branching fractionΓ(Y(4230)→e^(+)e^(−))B(Y(4230)→k^(+)k^(−)J/Ψ)is reported.

关键词： Y states charmonium-like states BESⅢ

Measurement of integrated luminosities at BESⅢ for data samples at center-of-mass energies between 4.0 and 4.6 GeV

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Chinese Physics C 2022年第11期46卷 53-63页

作者： M.Ablikim M.N.Achasov P.Adlarson S.Ahmed M.Albrecht R.Aliberti A.Amoroso M.R.An Q.An X.H.Bai Y.Bai O.Bakina R.Baldini Ferroli I.Balossino Y.Ban V.Batozskaya D.Becker k.Begzsuren N.Berger M.Bertani D.Bettoni F.Bianchi J.Bloms A.Bortone I.Boyko R.A.Briere A.Brueggemann H.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.F.Chang W.l.Chang G.Chelkov C.Chen G.Chen H.S.Chen M.l.Chen S.J.Chen T.Chen X.R.Chen X.T.Chen Y.B.Chen Z.J.Chen W.S.Cheng X.Chu G.Cibinetto F.Cossio J.J.Cui H.l.Dai J.P.Dai A.Dbeyssi R.Ede Boer D.Dedovich Z.Y.Deng A.Denig I.Denysenko M.Destefanis F.De Mori Y.Ding J.Dong l.Y.Dong M.Y.Dong X.Dong S.X.Du P.Egorov Y.l.Fan J.Fang S.S.Fang W.X.Fang Y.Fang R.Farinelli l.Fava F.Feldbauer G.Felici C.Q.Feng J.H.Feng k Fischer M.Fritsch C.Fritzsch C.D.Fu H.Gao Y.N.Gao Yang Gao S.Garbolino I.Garzia P.T.Ge C.Geng E.M.Gersabeck A Gilman k.Goetzen l.Gong W.X.Gong W.Gradl M.Greco M.H.Gu C.Y Guan A.Q.Guo l.B.Guo R.P.Guo Y.P.Guo A.Guskov T.T.Han W.Y.Han X.Q.Hao F.A.Harris k.k.He k.l.He F.H.Heinsius C.H.Heinz Y.k.Heng C.Herold M.Himmelreich T.Holtmann G.Y.Hou Y.R.Hou Z.l.Hou H.M.Hu J.F.Hu T.Hu Y.Hu G.S.Huang k.X.Huang l.Q.Huang l.Q.Huang X.T.Huang Y.P.Huang Z.Huang T.Hussain N Husken W.Imoehl M.Irshad J.Jackson S.Jaeger S.Janchiv Q.Ji Q.P.Ji X.B.Ji X.l.Ji Y.Y.Ji Z.k.Jia H.B.Jiang S.S.Jiang X.S.Jiang Y.Jiang J.B.Jiao Z.Jiao S.Jin Y.Jin M.Q.Jing T.Johansson N.kalantar-Nayestanaki X.S.kang R.kappert M.kavatsyuk B.C.ke I.k.keshk A.khoukaz P.kiese R.kiuchi R.kliemt l.koch O.B.kolcu B.kopf M.kuemmel M.kuessner A.kupsc W.kuhn J.J.lane J.S.lange P.larin A.lavania l.lavezzi Z.H.lei H.leithoff M.lellmann T.lenz C.li C.li C.H.li Cheng li D.M.li F.li G.li H.li H.li H.B.li H.J.li H.N.li J.Q.li J.S.li J.W.li ke li l.J li l.k.li lei li M.H.li P.R.li S.X.li S.Y.li T.li W.D.li W.G.li X.H.li X.l.li Xiaoyu li Z.Y.li H.liang H.liang H.liang Y.F.liang Y.T.liang G.R.liao l.Z.liao J.libby A.limphirat C.X.lin D.X.lin T.lin B.J.liu C.X.liu D.liu F.H.liu Fang liu Feng liu G.M.liu H.liu H.M.liu Huanhuan liu Huihui liu J.B.liu J.l.liu J.Y.liu k.l Institute of High Energy Physics Beijing 100049China Beihang University Beijing 100191China Beijing Institute of Petrochemical Technology Beijing 102617China Bochum Ruhr-University D-44780 BochumGermany Carnegie Mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China China Center of Advanced Science and Technology Beijing 100190China COMSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200433China G.I.Budker Institute of Nuclear Physics SB RAS(BINP) Novosibirsk 630090Russia GSI Helmholtzcentre for Heavy Ion Research GmbH D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Hangzhou Normal University Hangzhou 310036China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University of Science and Technology Luoyang 471003China Henan University of Technology Zhengzhou 450001China Huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN laboratori Nazionali di Frascati INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly INFN laboratori Nazionali di Frascati INFN Sezione di PerugiaI-06100PerugiaItaly INFN laboratori Nazionali di Frascati University of PerugiaI-06100PerugiaItaly INFN Sezione di Ferrara INFN Sezione di FerraraI-44122FerraraItaly INFN Sezione di Ferrara University of FerraraI-44122FerraraItaly Institute of Modern Physics Lanzhou 730000China Institute of Physics and Technology Peace Ave.54BUlaanbaatar 13330Mongolia Jilin University Changchun 130012China Johannes Gutenberg University of Mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany Joint Institute for Nuclear Research 141980 DubnaMoscow regionRussia Justus-liebig-Universitaet Giessen II.Physikalisches InstitutHeinrich-Buff-Ring 16

The integrated luminosities of data samples collected in the BESⅢ experiment in 2016-2017 at centerof-mass energies between 4.19 and 4.28 GeV are measured with a precision better than 1% by analyzing large-angle Bhabha scattering *** integrated luminosities of old datasets collected in 2010-2014 are updated by considering corrections related to detector performance,offsetting the effect of newly discovered readout errors in the electromagnetic calorimeter,which can haphazardly occur.

关键词： integrated luminosity e^(+)e^(-)annihilation Bhabha scattering

luminosities and energies of e^(+)e^(−) collision data taken between √s=4.61 GeV and 4.95 GeV at BESⅢ

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Chinese Physics C 2022年第11期46卷 64-75页

From December 2019 to June 2021,the BESⅢ experiment collected approximately 5.85 fb^(−1) of data at center-of-mass energies between 4.61 and 4.95 *** is the highest collision energy BEPCⅡ has reached to *** accumulated e^(+)e^(−) annihilation data samples are useful for studying charmonium(-like)states and charmed-hadron *** adopting a novel method of analyzing the production of A_(c)^(+)A_(c)^(-) pairs in e^(+)e^(−) annihilation,the center-of-mass energies are measured with a precision of 0.6 *** luminosities are measured with a precision of better than 1% by analyzing the events of large-angle Bhabha *** measurements provide important inputs to analyses based on these data samples.

关键词： luminosity center-of-mass energy BESⅢdetector