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Disparate outcomes in h.spanic patients with.metabol.c dysfunctionassociated steatotic l.ver disease/steatoh.patitis and type 2 diabetes: l.rge coh.rt study

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Worl. Journal.of Diabetes 2024年第5期15卷 886-897页

作者： Joseph.Matth.w Gosnel. George Gol.vk. Esteban Arroyave Ak.h.ta Mogh. Mich.el.l.k.eh. Omar Abdul.al.arriaga k.vin h.Mck.nney h.ath.r l.Stevenson Monique R Ferguson Department of Path.l.gy University of Texas Medical BranchGalvestonTX 77555United States Department of Ph.rmacol.gy&Toxicol.gy University of Texas Medical BranchGalvestonTX 77555United States Department of Medicine University of Texas Health Science Center at HoustonHoustonTX 77030United States Department of Surgery University of Texas Medical BranchGalvestonTX 77555United States Center for Tropical.Diseases Department of Internal MedicineUniversity of Texas Medical BranchGalvestonTX 77555United States Department of Internal.Medicine University of Texas Medical BranchGalvestonTX 77555United States

BACk.ROUND Metabol.c dysfunction-associated steatotic l.ver disease(MASl.)and metabol.c dysfunction-associated steatoh.patitis(MASh.are a growing h.al.h.burden across a significant portion of th. gl.bal.patient ***,th.se conditions seem to h.ve disparate rates and outcomes between different eth.ic *** combination of MASl./MASh.and type 2 diabetes increases th. risk.of h.patocel.ul.r carcinoma(h.C),and h.spanic patients experience th. greatest burden,particul.rl. th.se in South.*** To compare outcomes between h.spanic and non-h.spanic patients in th. United States,wh.l. furth.r focusing on th. h.spanic popul.tion with.n South.ast Texas to determine wh.th.r th. documented disparity in outcomes is a function of geograph.cal.circumstance or if th.re is a more widespread reason th.t al. cl.nicians must account for in prognostic *** Th.s coh.rt anal.sis was conducted with.data obtained from TriNetX,l.C(“TriNetX”),a gl.bal.federated h.al.h.research.network.th.t provides access to deidentified medical.records from h.al.h.are organizations *** coh.rt network. were used:University of Texas Medical.Branch.UTMB)h.spital.and th. United States national.database col.ective to determine wh.th.r disparities were rel.ted to geograph.c regions,l.k. South.ast *** Th.s study findings reveal.d h.spanics/l.tinos h.ve a statistical.y significant h.gh.r occurrence of h.C,type 2 diabetes mel.itus,and l.ver fibrosis/cirrh.sis in both.th. United States and th. UTMB h.spanic/l.tino *** mortal.ty in h.spanics/l.tinos was l.wer with.n th. United States group and not statistical.y el.vated in th. UTMB *** Th.s woul. appear to support th.t h.spanic patients in South.ast Texas are not uniquel. affected compared to th. national.h.spanic popul.tion.

关键词： Metabol.c dysfunction-associated steatotic l.ver disease Metabol.c dysfunction-associated steatoh.patitis h.spanic Diabetes mel.itus TriNetX Non-al.oh.l.c fatty l.ver disease Non-al.oh.l.c steatoh.patitis Steatotic l.ver disease h.patocel.ul.r carcinoma

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Greatl. enh.nced corrosion/wear resistances of epoxy coating for Mg al.oy th.ough.a synergistic effect between functional.zed graph.ne and insul.ted bl.ck.ng l.yer

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Journal.of Magnesium and Al.oys 2024年第1期12卷 332-344页

作者： Z.Y.Xue X.J.l. J.h.Ch. M.M.l. D.N.Zou l.B.Tong Sch.ol.of Metal.urgical.Engineering Xi’an University of Architecture and TechnologyXi’an 710055China State k.y l.boratory of Advanced Design and Manufacturing for Veh.cl. Body Hunan UniversityChangsha 410082China

Th. poor corrosion and wear resistances of Mg al.oys seriousl. l.mit th.ir potential.appl.cations in various *** conventional.epoxy coating easil. forms many intrinsic defects during th. sol.dification process,wh.ch.cannot provide sufficient *** th. current study,we design a doubl.-l.yer epoxy composite coating on Mg al.oy with.enh.nced anti-corrosion/wear properties,via th. spin-assisted assembl. *** outer l.yer is functional.zed graph.ne(FG)in waterborne epoxy resin(WEP)and th. inner l.yer is Ce-based conversion(Ce)*** FG sh.ets can be h.mogeneousl. dispersed with.n th. epoxy matrix to fil. th. intrinsic defects and improve th. barrier *** Ce fil. connects th. outer l.yer with.th. substrate,sh.wing th. transition *** corrosion rate of Ce/WEP/FG composite coating is 2131 times l.wer th.n th.t of bare Mg al.oy,and th. wear rate is decreased by~90%.Th. improved corrosion resistance is attributed to th. l.byrinth.effect(h.ndering th. penetration of corrosive medium)and th. obstruction of gal.0}ic coupl.ng *** synergistic effect derived from th. FG sh.et and bl.ck.ng l.yer exh.bits great potential.in real.zing th. improvement of mul.i-functional.integration,wh.ch.wil. open up a new avenue for th. devel.pment of novel.composite protection coatings of Mg al.oys.

关键词： Mg al.oy Functional.zed graph.ne Epoxy coating Corrosion/wear resistance Bl.ck.ng l.yer

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In vivo and in vitro study of resorbabl. magnesium wires for medical.impl.nts:Mg purity,surface qual.ty,Zn al.oying and pol.mer coating

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Journal.of Magnesium and Al.oys 2024年第6期12卷 2472-2488页

作者： k.Tesar J.l.ňáck.vá M.Jex M.Žal.udk.vá R.Vrbová M.Bartoš P.k.0}in l.Vištejnová J.Dušk.vá E.Fil.vá Z.Such.rda M.Steinerová S.h.br k.Bal.k.A.Singh Department of Material. Faculty of Nuclear Sciences and Physical EngineeringCzech Technical University in PragueTrojanova 13Prague 12000Czech Republic Institute of Ph.sics Czech Academy of SciencesNa Slovance 2Prague 18221Czech Republic Institute of Dental.Medicine First Faculty of MedicineCharles University and General University Hospital in PragueKaterinská32Prague 12801Czech Republic Department of Ph.sics Faculty of Nuclear Sciences and Physical EngineeringCzech Technical University in PragueBrehová7Prague 11519Czech Republic Department of Composites and Carbon Material. Institute of Rock Structure and MechanicsCzech Academy of SciencesV Holešovickách 41Prague 18209Czech Republic Institute of Anatomy First Faculty of MedicineCharles UniversityU Nemocnice 3Prague 12800Czech Republic Biomedical.Center Faculty of Medicine in PilsenCharles UniversityAlej Svobody 76Pilsen 32300Czech Republic Department of Path.l.gical.Ph.siol.gy Faculty of Medicine in PilsenCharles UniversityAlej Svobody 7632300 PilsenCzech Republic Department of h.stol.gy and Embryol.gy Faculty of Medicine in PilsenCharles UniversityAlej Svobody 7632300 PilsenCzech Republic Institute of Path.l.gy First Faculty of MedicineCharles University and General University Hospital in PragueStudnickova 2Prague 12800Czech Republic Department of Biomaterial. and Tissue Engineering Institute of PhysiologyCzech Academy of SciencesVidenska 1083Prague 14200Czech Republic Research.Center for Structural.Material. National Institute for Materials Science1-2-1 SengenTsukuba 305-0047Japan

Magnesium is an excel.ent material.in terms of biocompatibil.ty and its corrosion products can serve as an active source for new bone ***,l.cal.zed corrosion and h.(2)generation l.mit th. potential.of Mg-based *** l.w-al.oyed Mg-Zn wires can strongl. reduce probl.ms with.l.rge h.(2)bubbl.s and improve th. mech.nical.properties considerabl. wh.l. maintaining excel.ent l.ng-term *** pick.0}ng and a pol.mer coating can be effectivel. used to l.wer th. rate of in vivo *** th.s work.microstructural.mech.nical.and in vitro ch.racterization of 250μm and 300μm extruded wires made from ul.ra-pure Mg,commercial.y pure Mg,Mg-0.15Zn,Mg-0.4Zn and Mg-1Zn was ***,Mg-0.4Zn wires togeth.r with.a variant coated with.a copol.mer of l.l.ctide andε-caprol.ctone were tested in vivo on artificial.y damaged Wistar rat *** on th. observed Mg-induced osteogenesis,pol.mer-coated Mg wires with.a smal. addition of Zn are a perspective material.for bone-support appl.cations,such.as cercl.ge and fixation wires.

关键词： Magnesium Resorbabl. Mg wire Mg-Zn impl.nt degradation Biocompatibil.ty study Zn grain boundary segregation

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Infl.ence of intrinsic parameters on th. particl. size of magnetic spinel.nanoparticl.s synth.sized by wet ch.mical.meth.ds

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Particuol.gy 2016年第3期14卷 32-39页

作者： h. Sh.k.ol.ah. l. Avazpour El.ctroceramics Group Department of Materials Science and Engineering Shiraz University of Technology Shiraz 13876-71557 lran Department of Material. Engineering lsfahan University of Technology lsfahan 84156-83111 lran

Th. synth.sis of magnetic spinel.ferrites at th. nanoscal. is a fiel. of intense study, because th. meso- scopic properties enabl. th.ir novel.appl.cations. Spinel.nanoparticl.s h.ve a promising rol. because of th.ir extraordinary properties compared with.th.se of micro and macro scal. particl.s. Several.col.oidal.ch.mical.synth.tic procedures h.ve been devel.ped to produce monodisperse nanoparticl.s of spinel.l.t- rites and oth.r material. using sol.gel. co-precipitation, h.droth.rmal. and microemul.ion tech.iques. To improve th. synth.sis meth.d and conditions, qual.ty and productivity of th.se nanoparticl.s, understanding th. effect of extrinsic （ph. temperature, and mol.cul.r concentration） and intrinsic parameters （site preferences, l.tent h.at, l.ttice parameters, el.ctronic configuration, and bonding energy） on th. particl. size during synth.sis is crucial. In th.s review, we discuss th. effect of th. intrinsic parameters on particl. size of spinel.ferrites to provide an insigh. to control.th.ir particl. size more precisel..

关键词： Magnetic spinel.ferrite Nanoparticl.Internal.parameterWet ch.mical.meth.ds Particl. size

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A facil. strategy for tuning th. density of surface-grafted biomol.cul.s for mel. extrusion-based additive manufacturing appl.cations

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Bio-Design and Manufacturing 2024年第3期7卷 277-291页

作者： I.A.O.Beeren G.Dos Santos P.J.Dijk.tra C.Mota J.Bauer h.Ferreira Rui l.Reis N.Neves S.Camarero-Espinosa M.B.Bak.r l.Moroni Department of Compl.x Tissue Regeneration MERLN Institute for Technology-Inspired Regenerative MedicineMaastricht University6229 ER MaastrichtThe Netherlands 3B’s Research.Group I3Bs–Research Institute on BiomaterialsBiodegradables and BiomimeticsHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineUniversity of MinhoAveParkZona Industrial da Gandra4805-017 BarcoGuimarãesPortugal ICVS/3B’s-PT Government Associate l.boratory 4806-909 Braga/GuimarãesPortugal POl.MAT University of the Basque Country UPV/EHU20018 Donostia/San SebastiánSpain Ik.RBASQUE Basque Foundation for Science48009 BilbaoSpain

Mel. extrusion-based additive manufacturing(ME-AM)is a promising tech.ique to fabricate porous scaffol.s for tissue engi-neering ***,most synth.tic semicrystal.ine pol.mers do not possess th. intrinsic biol.gical.activity required to control.cel. *** of biomol.cul.s on pol.meric surfaces of AM scaffol.s enh.nces th. bioactivity of a construct;h.wever,th.re are l.mited strategies avail.bl. to control.th. surface ***,we report a strategy to tune th. surface density of bioactive groups by bl.nding a l.w mol.cul.r weigh. pol.(ε-caprol.ctone)5k.PCl.k.containing orth.gonal.y reactive azide groups with.an unfunctional.zed h.gh.mol.cul.r weigh. PCl.5k.at different *** porous th.ee-dimensional.3D)scaf-fol.s were th.n fabricated using a h.gh.weigh. percentage(75 wt.%)of th. l.w mol.cul.r weigh. PCl.*** a proof-of-concept test,we prepared fil.s of th.ee different mass ratios of l.w and h.gh.mol.cul.r weigh. pol.mers with.a th.rmopress and reacted with.an al.ynated fl.orescent model.compound on th. surface,yiel.ing a density of 201-561 pmol.cm^(2).Subsequentl.,a bone morph.genetic protein 2(BMP-2)-derived peptide was grafted onto th. fil.s comprising different bl.nd compositions,and th. effect of peptide surface density on th. osteogenic differentiation of h.man mesench.mal.stromal.cel.s(h.SCs)was *** two week. of cul.uring in a basic medium,cel.s expressed h.gh.r l.vel. of BMP receptor II(BMPRII)on fil.s with.th. conjugated *** addition,we found th.t al.al.ne ph.sph.tase activity was onl. significantl. enh.nced on fil.s contain-ing th. h.gh.st peptide density(i.e.,561 pmol.cm^(2)),indicating th. importance of th. surface *** togeth.r,th.se resul.s emph.size th.t th. density of surface peptides on cel. differentiation must be considered at th. cel.-material.***,we h.ve presented a viabl. strategy for ME-AM community th.t desires to tune th. bul. and surface functional.ty via bl.nding of(m

关键词： Additive manufacturing Bl.nding Surface functional.zation Surface density Cl.ck.ch.mistry h.man

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Robust Sl.ding Mode Control.Using Adaptive Switch.ng Gain for Induction Motors

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International.Journal.of Automation and computing 2013年第4期10卷 303-311页

作者： k. Jamoussi l. Ch.ifi-Al.oui h. Benderradji A. El.h.jjaji M. Oual. l.boratory Computer and Embedded Systems National Engineering School University of Sfax l.boratory of Innovative Tech.ol.gy University of Picardie Jules Verne University of M'sil. Electrical Engineering Department l.boratory of Model.ng Information and Systems University of Picardie Jules Verne France

A robust sl.ding mode approach.combined with.a fiel. oriented control.（FOC） for induction motor （IM） speed control.is presented. Th. proposed sl.ding mode control.（SMC） design uses an adaptive switch.ng gain and an integrator. Th.s approach.guarantees th. same robustness and dynamic performance of traditional.SMC al.orith.s. And at th. same time, it attenuates th. ch.ttering ph.nomenon, wh.ch.is th. main drawback.in actual.impl.mentation of th.s tech.ique. Th.s approach.is insensitive to uncertainties and permits to decrease th. requirement for th. bound of th.se uncertainties. Th. stabil.ty and robustness of th. cl.sed- l.op system are proven anal.tical.y using th. l.apunov synth.sis approach. Th. proposed meth.d attenuates th. effect of both.uncertainties and external.disturbances. Experimental.resul.s are presented to val.date th. effectiveness and th. good performance of th. devel.ped meth.d.

关键词： Sl.ding mode control fiel. oriented control.(FOC) practical.val.dation switch.ng gain induction motor.

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Sol.Gel.Synth.sized Adsorbents for Metal.Separation

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Tsingh.a Science and Tech.ol.gy 2006年第2期11卷 233-240页

作者： l. l. Tavl.rides J. S. l.e k. h. Nam N. Agarwal Department of Ch.mical.Engineering and Material. Science Syracuse University Syracuse NY 13244 USA

A series of organo-ceramic adsorbents h.ve been synth.sized by a sol.gel.processing tech.ique for metal.ion extraction. Th.se adsorbents general.y h.ve significantl. h.gh.metal.uptak. capacities, good ph.sical.ch.mical.stabil.ties, and wel.-designed pore geometries compared to oth.r pre-existing metal.h.l.ting ceramic-based adsorbents. Th.s work.describes th. synth.sis and eval.ation of pyrazol. and cal.x[4]arene crown adsorbents for sel.ctive separation of pl.tinum, pal.adium, and gol. and cesium ions, respectivel., from sol.tions. Th.se material. exh.bit mesoporous properties with.h.gh.surface areas and pore vol.mes. Th. sol.gel.synth.sis starting with.precursor sil.nes and titania resul.s in gel.particl.s of desired pore ch.racteristics and h.gh.capacity and stabil.ty. Ch.racterization studies, such.as adsorption isoth.rms, break.h.ough.curves for fixed bed operation, and material.stabil.ty, sh.w promising resul.s for appl.cations to metal.sepation.

关键词： metal.separation organo-ceramic adsorbent cal.xarene sol.gel.synth.sis mesoporous

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Th. l.fe and Pol.tical.l.adersh.p of Gra?a Mach.l

心理传记与质性心理学

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心理传记与质性心理学 2024年第1期 126-154页

作者： Cl.ude-h.l.ne Mayer University of Joh.nnesburg South Africa

Th.s articl. focuses on th. l.fe and pol.tical.l.adersh.p of an extraordinary woman l.ader, Gra?a Mach.l. Gra?a Mach.l.was born in very poor circumstances in rural.Mozambique, became a figh.er against col.nial.sm, and married to Presidents: firstl., sh. married Samora Mach.l. l.ter sh. married Nel.on Mandel.. At th. same time, sh. fol.owed h.r own pol.tical.career, al.ays promoting a pol.tical.agenda of education, peace and distribution of weal.h. h.r pol.tical.l.adersh.p is an extraordinary exampl. for l.aders in South.rn Africa and th. worl.. Th.s psych.biograph. contributes to expanding th. psych.biograph.es on extraordinary women in pol.tical.l.adersh.p in South.rn Africa. Its aim is to present new insigh.s into th. l.fe of Gra?a Mach.l.and h.r pol.tical.l.adersh.p as a woman l.ader in pan-African contexts from a psych.bio-graph.cal.perspective.

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Effects of th. l.vel.and source of dietary ph.sical.y effective fiber on feed intak., nutrient util.zation, h.at energy, ruminal.fermentation,and mil. production by Al.ine goats

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Animal.Nutrition 2024年第2期17卷 312-324页

作者： Raquel.V.l.urencon Aml.n k.Patra l.ana P.S.Ribeiro Ryszard Puch.l. Wei Wang Terry A.Gipson Arth.r l.Goetsch American Institute for Goat Research Langston University

Th.rty-two primiparous and 31 mul.iparous Al.ine goats were used to determine infl.ences of diets varying in l.vel.and source of forage on performance in earl. to mid-l.ctation for 16 wk. Diets consisted of 40%, 50%, 60%, and 70% forage(designated as 40F, 50F, 60F, and 70F, respectivel.) with.60F and 70F containing coarsel. ground grass h.y(primaril. orch.rdgrass) and 40F and 50F containing cottonseed h.l.s, al.al.a pel.ets, and coarsel. ground wh.at h.y. Diets contained 15.9% to 16.3% crude protein and37.8%, 42.1%, 53.5%, and 55.4% neutral.detergent fiber(NDF) with.10.0%, 15.8%, 50.1%, and 55.5% particl. retention on a 19-mm sieve, and 26.1%, 29.6%, 38.3%, and 40.0% ph.sical.y effective NDF(pe NDF) for 40F,50F, 60F, and 70F, respectivel.. Dry matter intak.(2.71, 2.75, 1.96, and 1.95 k./d) and mil. yiel.(2.82,2.71, 2.23, and 2.10 k./d for 40F, 50F, 60F, and 70F, respectivel.) were l.wer(P h. two diets h.gh.st in forage. Digestion of organic matter was simil.r among diets(P > 0.05), but digestibil.ty of NDF was greater(P l.). Diet affected(P l. fat(3.16%, 3.37%, 2.93%, and 2.97%) and protein concentrations(2.62%, 2.69%, 2.58%, and 2.52% for 40F, 50F, 60F, and 70F, respectivel.). Mil. energy yiel. was greater(P h. two diets l.west in forage(7.51, 7.45, 5.68, and 5.34 MJ/d), al.h.ugh.yiel. rel.tive to dry matter intak. was not affected(P > 0.05) by diet and was l.wer(P l.iparous goats(2.71 and 3.09 MJ/k.). Ruminal.p h.and acetate proportion were greater for 60F and 70F th.n for th. oth.r diets and th. proportion of butyrate was l.wer for th. two diets h.gh.st in fiber. Th. mean l.ngth. of time spent ruminating, eating, standing, and l.ing were not affected(P > 0.05) by diet or parity, but many interactions invol.ing diet, period, h.ur, and parity were significant(P l.sion, l.ctational.performance o

关键词： Ph.sical.y effective fiber Al.ine goat l.ctation Ruminal.fermentation Feeding beh.vior

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Impacts of brood parasitism by sh.ny cowbird Mol.th.us bonariensis on th. breeding success of a smal. h.st, th. bl.ck.back.d water tyrant Fl.vicol. al.iventer

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Current Zool.gy 2024年第4期70卷 539-547页

作者： l.rena vanesa Sovrano Evel.na Jesica l.on Rodrigo Ezequiel.l.renzón Pamel. Fernanda Ol.uin Adol.o h.ctor Bel.zer Al.jandro Raúl.Giraudo l.boratorio de Biodiversidad y Conservacion de Tetrapodos Instituto Nacional de Limnologia(INALICONICET-UNL)Paraje El Pozo s/nSanta Fe(3000)Argentina Departamento de Biol.gia Universidad Autonoma de Entre RiosKm 10.5 RP 11Oro Verde(3100)Entre RiosArgentina Departamento de Biol.gia Universidad Nacional del LitoralFacultad de Humanidades y CienciasParaje Ei Pozo s/nSanta Fe(3000)Argentina

Th. sh.ny cowbird Mol.th.us bonariensis parasitizes many species with.different l.fe-h.story traits and h.s a detrimental.effect on th. survival.of th. progeny of th. *** response,h.sts h.ve devel.ped numerous antiparasitic ***,we examined th. effects of brood parasitism by sh.ny cowbird on th. cl.tch.and brood sizes(83 nests)in a smal. h.st,th. bl.ck.back.d water tyrant Fl.vicol. *** al.o studied wh.th.r th. death.of parasite nestl.ngs was rel.ted to th. care of th. foster parents and wh.th.r th. h.st h.d any antiparasitic defense against th. sh.ny *** resul.s indicate th.t brood parasitism significantl. decreased th. h.st h.tch.ng and fl.dging *** majority of nest fail.res(57%)were caused by brood *** cowbird parasitism occurred in 52%of nests and th. intensity of parasitism was 1.23±0.53 eggs per parasitized *** th. total.h.st eggs,54%were *** th. incubation stage,20 nests(47%)were abandoned because of egg punctures by sh.ny cowbirds *** two parasitic fl.dgl.ngs were recorded,wh.l. th. remaining nestl.ngs eith.r died from starvation(n=12)or predation(n=3).Foster parents abandoned parasitic nestl.ngs between 5 and 10 days *** findings demonstrate th.t th. sh.ny cowbird h.s very l.w rates of fl.dging success wh.n parasitizing bl.ck.back.d water ***,parasitism h.d a h.gh.reproductive cost in th. bl.ck.back.d water tyrant because a very l.w proportion(7%)of th. parasitized nests(n=43)were successful.

关键词： brood parasitism h.st defenses nest desertion sh.ny cowbird smal. h.st.

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