检索结果-南通市图书馆

Rare Metals 2021年第1期40卷 202-211页

作者： Jiang-Fan Wang Shu-xin Bai Yi-Cong ye li-An Zhu Hong Zhang College of Aerospace Science and Engineering National University of Defense TechnologyChangsha 410073China

The purity,preferred orientation,microstructure,microhardness,bonding strength,thickness uniformity and thermal stability of rhenium(Re)coatings prepared on graphite wafers by chemical vapor deposition(CVD)and electrodeposition(ED)in molten salts were comparatively studied in this *** was found that carbon(0.0140 wt%)and oxygen(0.0067 wt%)were the primary impurities for CVD and ED Re coatings,*** diffusion of carbon into CVD Re coating caused higher microhardness near the substrate and helped to improve the bonding strength at the same *** preferred orientation,microstructure and microhardness of ED Re coating were all susceptible to *** coating deposition uniformity of ED Re is obviously better than that of CVD Re coating,due to its intrinsic ***(002)-oriented,coarse columnar CVD Re coating exhibited better thermal stability compared with that of the-oriented,fiber-like columnar ED Re coating,while the ED Re grains grew remarkably and the microstructure evolved toward the similar structure of CVD Re after annealing *** diversity of Re coatings in microstructure could be attributed to the mobility of grain boundaries(affected by temperature and impurity)during deposition processes.

关键词： Rhenium coating Graphite wafer Chemical vapor deposition Electrodeposition Molten salt Grain boundary mobility

Enhancing room-temperature thermoelectric performance of n-type Bi_(2)Te_(3)-based alloys via sulfur alloying

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2021年第3期40卷 513-520页

作者： Feng liu ye-Hao Wu Qi Zhang Tie-Jun Zhu xin-Bing Zhao State Key laboratory of Silicon Materials School of Materials Science and EngineeringZhejiang UniversityHangzhou 310027China

Bismuth-telluride-based alloys are the best thermoelectric materials used in commercial solid-state refrigeration near room ***,for n-type polycrystalline alloys,their thermoelectric figure of merit(zT) values at room temperature are often less than1.0,due to the high electron concentration originating from the donor-like effect induced by the mechanical deformation ***,carrier concentration for better performance near room temperature was optimized through manipulating intrinsic point defects by sulfur *** alloying significantly decreases antisite defects concentration and suppresses donor-like effect,resulting in optimized carrier concentration and reduced electronic thermal *** hot deformation process was also applied to improve carrier mobility due to the enhanced *** a result,a high zT value of 1 at 300 K and peak zT value of 1.1 at 350 K were obtained for the twice hot-deformed Bi_(2) Te_(2.7)Se_(0.21)S_(0.09) sample,which verifies sulfur alloying is an effective method to improve thermoelectric performance of n-type polycrystalline Bi2 Te3-based alloys near room temperature.

关键词： Bismuth telluride Thermoelectric Point defect Sulfur alloying Hot deformation

Quantum key distribution system against the probabilistic faint after-gate attack

在线全文

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2020年第11期72卷 43-47页

作者： Meng ye Jian-Hui li Yong Wang Peng Gao xin-xin lu Yong-Jun Qian Power Generation Company GuangZhou 510700China Anhui Qasky Quantum Technology Co. Ltd.Wuhu 241102China

In practical quantum key distribution(QKD)systems,a single photon-detector(SPD)is one of the most vulnerable *** after-gate attack is a universal attack against the ***,the original faint after-gate attack can be discovered by monitoring the *** paper presents a probabilistic generalization of the attack,which we refer to as probabilistic faint after-gate attack,by introducing probability control *** countermeasures for photocurrent monitoring may fail in detecting the eavesdropper under some specific *** mitigate this threat,we provide a method to determine the detectable boundary in the limitation of precision of photocurrent monitoring,and investigate the security of QKD systems under such boundaries using the weak randomness model.

关键词： quantum key distribution practical security single photon-detector weak randomness model

A retrospective study on sperm cryopreservation in 1034 patients diagnosed with cancer in southern China

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2023年第4期25卷 499-504页

作者： Qi-ling Wang Gui-Fang ye Kai-xin Zhong xin Wu Wei-xin lin lu-lu luo xin-Zong Zhang Wei-Jie Zhu NHC Key laboratory of Male Reproduction and Genetics Guangzhou 510600China Department of Andrology Guangdong Provincial Reproductive Science InstituteGuangdong Provincial Fertility HospitalGuangzhou 510600China Human Sperm Bank of Guangdong Province Guangzhou 510600China Institute of Reproductive Immunology College of Life Science and TechnologyJinan UniversityGuangzhou 510632China

Sperm cryopreservation is an effective fertility preservation method for cancer patients before anticancer treatments. However, thereare little data on fertility preservation in large cohorts of patients with cancer in southern China. This retrospective cross-sectionalstudy aimed to assess the fertility preservation status of 1034 newly diagnosed male patients with cancer in the Human SpermBank of Guangdong Province in southern China (Guangzhou, China). Of these, 302 patients had reproductive system tumors,mostly testicular cancers (99.0%), and 732 had other tumors, including lymphoma (33.1%), gastrointestinal cancer (16.3%),nasopharyngeal carcinoma (15.7%), leukemia (7.7%), sarcoma (3.6%), and others (23.6%). Patients with reproductive systemtumors had lower sperm concentration and prefreezing and post-thawing progressive motility than those with non-reproductive systemtumors (all P lity, and normal morphology rate were observed betweenpatients with and without anticancer surgery before sperm cryopreservation (all P l 30, 2022, 63 patients usedtheir cryopreserved sperm for assisted reproductive technology treatments and 39 pregnancies were achieved. This study providesvaluable data on the fertility preservation status in newly diagnosed cancer patients in southern China, demonstrating that patientswith reproductive system tumors had poor sperm quality for their pretreatment fertility preservation.

关键词： cancer fertility preservation sperm cryopreservation sperm quality

An endoparasitoid uses its egg surface proteins to regulate its host immune response

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insect Science 2022年第4期29卷 1030-1046页

作者： Zi-Wen Teng Hui-Zi Wu xin-Hai ye Qi Fang Hong-Xu Zhou Gong-Yin ye China-Australia Cooperation Base of Crop Health and Invasive Species China-Australia Joint Institute of Agricultural and Environmental HealthCollege of Plant Health and MedicineQingdao Agricultural UniversityQingdaoShandong ProvinceChina State Key laboratory of Rice Biology Ministry of Agricultural and Rural Affairs Key Laboratory of Molecular Biology of Crop Pathogens and InsectsKey Laboratory of Biology of Crop Pathogens and Insects of Zhejiang ProvinceInstitute of Insect SciencesZhejiang UniversityHangzhouChina

With proteomic analysis,we identified 379 egg surface proteins from an endoparasitoid,Cotesia *** containing conserved enzymatic domains constitute a large proportion of egg surface *** proteins,such as superoxidase dismutase,homolog of *** 32-kDa protein,and immunoevasive protein-2A,are classical parasitism factors that have known functions in host immunity *** assays revealed that a novel egg surface protein,*** egg surface serpin domain-containing protein had the same function as a *** venom serpin,as both suppressed host melanization in a dose-dependent *** egg surface serpin domain-containing protein is mainly transcribed in *** oocytes with follicular cells,and it is located on both the anterior and posterior sides of the mature egg ***,we used lC-MS/MS to identify 586 binding proteins sourced from *** plasma located on the eggshell surface of ***,which included some immunity-related *** results not only indicate that *** uses its egg surface proteins to reduce the immune response of its host but also imply that endoparasitoid egg surface proteins might be a new parasitism factor involved in host immune regulation.

关键词： egg surface protein immune regulation melanization parasitism factor parasitoid wasp

Mitochondrial DNA mutations associated with aminoglycoside induced ototoxicity

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Otology 2017年第1期12卷 1-8页

作者： Zewen Gao ye Chen Min-xin Guan Division of Clinical Genetics and Genomics The Children's HospitalZhejiang University School of Medicine Institute of Genetics Zhejiang University and Department of GeneticsZhejiang University School of Medicine

Aminoglycosides(Am An) are widely used for their great efficiency against gram-negative bacterial infections. However, they can also induce ototoxic hearing loss, which has affected millions of people around the world. As previously reported, individuals bearing mitochondrial DNA mutations in the 12 S rRNA gene, such as m.1555A>G and m.1494C>T, are more prone to Am An-induced ototoxicity. These mutations cause human mitochondrial ribosomes to more closely resemble bacterial ribosomes and enable a stronger aminoglycoside interaction. Consequently,exposure to Am An can induce or worsen hearing loss in these individuals. Furthermore, a wide range of severity and penetrance of hearing loss was observed among families carrying these mutations. Studies have revealed that these mitochondria mutations are the primary molecular mechanism of genetic susceptibility to Am An ototoxicity, though nuclear modifier genes and mitochondrial haplotypes are known to modulate the phenotypic manifestation.

关键词： Aminoglycosides ototoxicity Genetic susceptibility Mitochondrial DNA mutations

Research on Ultra-wide Bandwidth low-frequency Signal Channelization for xinjiang 110m Radio Telescope

在线全文

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2023年第12期23卷 263-274页

作者： Hai-long Zhang Ya-Zhou Zhang Meng Zhang Jie Wang Jian li xin-Chen ye xin Pei xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China University of Chinese Academy of Sciences Beijing 100049China Key laboratory of Radio Astronomy Chinese Academy of SciencesNanjing 210008China National Astronomical Data Center Beijing 100101China School of Cyber Science and Engineering Qufu Normal UniversityQufu 273165China

Aiming at the subband division of ultra-wide bandwidth low-frequency(UWl)signal(frequency coverage range:704–4032 MHz)of the xinjiang 110 m QiTai radio Telescope(QTT),a scheme of ultra-wide bandwidth signal is ***,we analyze the effect of different window functions such as the Hanning window,Hamming window,and Kaiser window on the performance of finite impulse response(FIR)digital filters,and implement a critical sampling polyphase filter bank(CS-PFB)based on the Hamming window FIR digital ***,we generate 3328 MHz simulation data of ultra-wideband pulsar baseband in the frequency range of 704–4032 MHz using the ultra-wide bandwidth pulsar baseband data generation algorithm based on the 400 MHz bandwidth pulsar baseband data obtained from Parkes CASPSR ***,we obtain 26 subbands of 128 MHz based on CS-PFB and the simulation data,and the pulse profile of each subband by coherent dispersion,integration,and ***,the phase of each subband pulse profile is aligned by non-coherent dedispersion,and to generate a broadband pulse profile,which is basically the same as the pulse profile obtained from the original data using *** experimental results show that the scheme for the QTT UWl receiving system is feasible,and the proposed channel algorithm in this paper is effective.

关键词： pulsars general-methods data analysis-techniques miscellaneous

Improving remote sensing-based net primary production estimation in the grazed land with defoliation formulation model

在线全文

学校读者我要写书评

暂无评论

Journal of Mountain Science 2019年第2期16卷 323-336页

作者： ye Hui HUANG Xiao-tao lUO Ge-ping WANG Jun-bang ZHANG Miao WANG xin-xin State Key laboratory of Desert and Oasis Ecology Xinjiang Institute of Ecology and Geography Chinese Academy of Sciences China University of Chinese Academy of Sciences Key laboratory of Restoration Ecology for Cold Regions in Qinghai Northwest Institute of Plateau Biology Chinese Academy of Sciences Key laboratory of Ecosystem Network Observation and Modeling Institute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences Northwest land and Resources Research Center Shaanxi Normal University Ministry of Education Key laboratory of Biodiversity Science and Ecological Engineering Institute of Biodiversity Science Fudan University

Remote sensing(RS) technologies provide robust techniques for quantifying net primary productivity(NPP) which is a key component of ecosystem production management. Applying RS, the confounding effects of carbon consumed by livestock grazing were neglected by previous studies, which created uncertainties and underestimation of NPP for the grazed lands. The grasslands in xinjiang were selected as a case study to improve the RS based NPP estimation. A defoliation formulation model(DFM) based on RS is developed to evaluate the extent of underestimated NPP between 1982 and 2011. The estimates were then used to examine the spatiotemporal patterns of the calculated NPP. Results show that average annual underestimated NPP was 55.74 gC·m^(-2)yr^(-1) over the time period understudied, accounting for 29.06% of the total NPP for the xinjiang grasslands. The spatial distribution of underestimated NPP is related to both grazing intensity and time. Data for the xinjiang grasslands show that the average annual NPP was 179.41 gC·m^(-2)yr^(-1), the annual NPP with an increasing trend was observed at a rate of 1.04 gC·m^(-2)yr^(-1) between 1982 and 2011. The spatial distribution of NPP reveals distinct variations from high to low encompassing the geolocations of the Tianshan Mountains, northern and southern xinjiang Province and corresponding with mid-mountain meadow, typical grassland, desert grassland, alpine meadow, and saline meadow grassland types. This study contributes to improving RS-based NPP estimations for grazed land and provides a more accurate data to support the scientific management of fragile grassland ecosystems in xinjiang.

关键词： Remote sensing Defoliation formulation model Net primary production Grazed land Spatial-temporal patterns xinjiang

Blocking VEGF signaling augments interleukin-8 secretion via MEK/ERK/1/2 axis in human retinal pigment epithelial cells

在线全文

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2020年第7期13卷 1039-1045页

作者： lin-Bin Zhou ye-Qi Zhou xin-Yu Zhang State Key laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Soochow University Affiliated Children’s Hospital SuzhouJiangsu ProvinceChina

AIM:To identify proangiogenic factors engaged in neovascular age-related macular degeneration(AMD)except vascular endothelial growth factor(VEGF)from human retinal pigment epithelial(h RPE)cells and investigate the underlying ***:VEGF receptor 2(VEGFR2)in ARPE-19 cells was depleted by si RNA transfection or overexpressed through adenovirus *** m RNA and the protein levels of interleukin-8(Il-8)in ARPE-19 cells were measured by quantitative real-time polymerase chain reaction and enzyme-linked immunosorbent assay *** protein levels of AKT,p-AKT,MEK,p-MEK,ERK1/2,p-ERK1/2,JNK,p-JNK,p38 and p-p38 were detected by Western blotting.A selective chemical inhibitor,lY3214996,was employed to inhibit phosphorylation of ERK1/*** viability was determined by MTT ***:Knockdown of VEGFR2 in ARPE-19 cells robustly augmented Il-8 production at both the m RNA and the protein *** VEGFR2 substantially enhanced phosphorylation of MEK and ERK1/2 while exerted no effects on phosphorylation of AKT,JNK and *** ERK1/2 phosphorylation by lY3214996 reversed changes in VEGFR2 knockdown-induced Il-8 upregulation at the m RNA and the protein levels with no effects on cell ***2 overexpression significantly reduced Il-8 generation at the m RNA and the protein ***:Blockade of VEGF signaling augments Il-8 secretion via MEK/ERK1/2 axis and overactivation of VEGF pathway decreases Il-8 production in h RPE *** Il-8 expression after VEGF signaling inhibition in h RPE cells may be responsible for being incompletely responsive to anti-VEGF remedy in neovascular AMD,and Il-8 may serve as an alternative therapeutic target for neovascular AMD.

关键词： age-related macular degeneration vascular endothelial growth factor signaling anti-vascular endothelial growth factor therapy retinal pigment epithelial cells interleukin-8

Total Synthesis of a Hyperbranched N-linked Hexasaccharide Attached to ATCV-1 Major Capsid Protein without Precedent

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2019年第1期37卷 42-48页

作者： Yong-Shi Wang Yong Wu De-Cai Xiong xin-Shan ye State Key laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesPeking UniversityXue Yuan Road No.38Beijing 100191China State Key laboratory of Drug Research Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 200031China

Summary of main observation and conclusion The N-glycans attached to some chloroviruses comprise a hyperbranched core structure without *** are interested in the chemical synthesis of the hexasaccharide attached to ATCV-1 (Acanthocystis turfacea Chlorella virus 1)for its distinct *** exploring four routes,the target hexasaccharide 2 was successfully synthesized for the first time in overall 10% yield over 8 steps from thioglycoside building *** synthetic protocol is characterized by the three-component one-pot glycosylation and the regioselective glycosylation *** disclosed synthetic approach to this new type of N-glycans will facilitate the in-depth understanding of their biological functions.

关键词： chemical routes functions