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Open Journal of Pediatrics 2016年第3期6卷 252-255页

作者： Angèle Kalmogho Abdoulaye Ouattara Chantal Zoungrana Caroline Yonaba Flore Ouédraogo léonce ilboudo laure Toguyeni ludovic Kam Département de Pédiatrie Centre Hospitalier Universitaire Yalgado Ouédraogo Ouagadougou Burkina Faso Service de Hépato Gastro Entérologie Centre Hospitalier Universitaire Yalgado Ouédraogo Ouagadougou Burkina Faso Service de Pédiatrie Médicale du Centre Hospitalier Universitaire Pédiatrique Charles de Gaulle Ouagadougou Burkina Faso

Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD), characterized by acute exacerbations and remissions. We report the clinical case of an infant, an 8 months female baby. The time between disease onset and diagnosis of the disease was 6 months. It was from an unknown etiology. The main clinical picture was weight stagnation, mucoid bloody diarrhea, and rectal bleeding. The macroscopic aspect in anorectoscopy was an erythematous mucosa with healthy beaches intervals. The mucosa was bleeding easily on contact. Pathological examination realized within the various lesions of the association was highly suggestive. The suggested treatment was made of symptomatic, corticosteroids and immunosuppressant’s therapy. Conclusion: Ulcerative colitis is rare in infants and difficult to manage in our tropical context.

关键词： Ulcerative Colitis Infant Pediatric Burkina Faso

Hypoglycaemiac Medicinal Plants Used by Diabetics at CNHU-HKM

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Journal of Diabetes Mellitus 2024年第1期14卷 41-48页

作者： Annelie Kerekou Hode Hubert Dedjan léonce Gaba Department of Endocrinology Metabolism Nutrition of CNHU-HKM Cotonou Bénin Department of Medicine and Medical Specialties of the CHUD-OP Porto-Novo Benin

Introduction: Diabetes is a major public health problem. Medicinal plants are frequently used either combine with industrial treatment or exclusively, in Africa and particularly in Benin. Our study aims to identify the different medicinal plants used by diabetic patients at the CNHU-HKM. Method: we carried out a descriptive and analytical cross-sectional study. It took place at the University Clinic of Endocrinology, Metabolism and Nutrition of CNHU-HKM over a of 3 months period from 20th of June to 16th of September, 2022, over diabetic followed-up. Results: One hundred and seventy-three (173) patients were gathered using an anonymous inquiry form. In the study population, the age of the patients varied between 31 and 75 years with an average age of 59 +/− 1.43 years, women represented 59% with a sex ratio (male/female) of 0.69. Sixty-five (65) or 37.6% of the population had used medicinal plants. Among given reasons for using medicinal plants were, mainly the positiveness on a third party. Data analysis outcome twenty-nine species of plants belonging to twenty (20) botanical families, the most represented being the Annonaceae and Fabaceae. The most used species are Phyllanthus amarus (hlenwé in fon), Mangifera indica (mangatin in fon), Momordica charantia (gninsikin in fon), Combretum micranthum (kinkéliba in fon), and Picralima nitida (ayorkpè in fon). Most used parts of the plants are the leaves. The recipes are prepared mainly by infusion and are administered exclusively by mouth. Most of the patients who used the hypoglycaemic medicinal plants were satisfied and no adverse effects were reported by them. Conclusion: Hypoglycaemic medicinal plants could be subjected to pharmacognosy and marketed due to their richness in active components, after further toxicological studies.

关键词： Diabetes Hypoglycaemic Medicinal Plants Glycemic Imbalance Chronic Complications Benin

Petrographic and Geochemical Characters of Granites of the Banfora Belt, Burkina Faso (West Africa)

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International Journal of Geosciences 2024年第9期15卷 682-697页

作者： Abdoulaye Ouedraogo Seta Naba Hermann ilboudo laboratoire Gosciences et Environnement (laGE) Dpartement des Sciences de la Terre Unit de Formation et de Recherche en Sciences de la Vie et de la Terre Universit Joseph KI-ZERBO Ouagadougou Burkina Faso Bureau des Mines et de la Gologie du Burkina (BUMIGEB) Ouagadougou Burkina Faso

The Banfora’s birimian greenstones belt is located in the western part of Burkina Faso (west Africa). Recent petrographic and lithogeochemical studies have highlighted plutons intruding the metasedimentary and metavolcanic series. These plutonic rocks are composed of leucogranites belonging to the so-called Ferkessedougou’s or Ferké’s batholith, granites, granodiorites, monzodiorites and quartz monzonites. From the lithogeochemical studies, these plutonic rocks have a calc-alkaline and peraluminous character. The rare earth elements spectra of the Ferké’s leucogranites let distinguished two sub-facies. One of the sub-facies is composed of quartz monzonite to granite, while the other is granitic sensu stricto. However, all these plutonic rocks were emplaced in a geodynamic context of subduction followed by collision.

关键词： Burkina Faso Banfora Greenstones Belt Plutons Geodynamic Context Subduction

Optimized Adsorption of Small and Medium Molecules by a Biosorbent Based on Hevea Hulls

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Journal of Materials Science and Chemical Engineering 2024年第9期12卷 69-83页

作者： Djedjess Essoh Jules César Meledje Yapo Hermann Aristide Yapi David léonce Kouadio Djamatchè Paul Valéry Akesse Kolo Yeo laboratoire des Sciences Physiques Fondamentales et appliques Ecole Normale Suprieure dAbidjan Abidjan Cte dIvoire Mathmatiques physiques Chimie Physique UFR Environnement Universit Jean Lorougnon Gud Daloa Cte dIvoire

In the context of the recovery of agricultural waste, many researches have focused on the preparation of adsorbents from natural waste from fruit trees, egg shells, palm waste or sawdust. This work aims to optimize the preparation of a biosorbent from rubber hulls by studying its ability to adsorb small and medium molecules. The influence of parameters such as drying temperature (X1), particle size (X2), stirring time (X3) and sodium hypochloride mass (X4) was studied. The results indicate that the model used for biosorbent optimization on methylene blue and iodine index is significant. In addition, this model has greater adsorption capabilities on small molecules than with large molecules. Statistical analysis of the data shows that temperature is the most influential factor in the adsorption of small molecules. On the other hand, particle size has a significant influence on the adsorption of large molecules. The optimum biosorbent preparation values are 1.0 for drying temperature (X1), −1.0 for biosorbent grain size (X2), 1.0 for stirring time (X3) and 1.0 for sodium hypochloride mass (X4).

关键词： Optimization Biosorbent Methylene Blue Index Iodine Index Rubber Hulls

Study of Some Biodemographic Parameters of Caryedon serratus Olivier (Coleoptera: Chrysomelidae) Insect Pest of Tamarind (Tamarindus indica lin.) Fruit, in Burkina Faso

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Advances in Entomology 2024年第2期12卷 67-77页

作者： Kilo Francine Marina Ki Koï Wenceslas Kam Emmanuel Kabore Antoine Sanon Zakaria ilboudo laboratoire d’Entomologie Fondamentale et Appliqué e (LEFA) UFR/SVT Universit&eacute Joseph KI-ZERBO Ouagadougou Burkina Faso Institut Supé rieur du D&eacuteveloppement Durable Universit&eacute de Fada N’gourma Fada N’gourma Burkina Faso

The lack of food security leads us to turn to the riches of the forest, namely non-timber forest products (NTFP) and timber forest products (TFP). In Burkina, these products are a source of income for families, improving their living conditions. Tamarindus indica l. that is a NFTP, is widely used in both rural and urban areas. Unfortunately, tamarind is subject to attack by Caryedon serratus. Its biological activity begins on the fruit before the harvest. The aim of our study is to evaluate some biodemographic parameters of the insect pest C. serratus Olivier. First100 healthy T. indica pods were placed in contact with ten pairs of C. serratus for 24 hours. 25 pods, each carrying a maximum of two eggs, were divided into five batches of 5 pods. Then a pair of C. serratus aged less than 24 h was placed in contact with 4 healthy pods for 24 h. Every day, the pair was removed and transferred to another box containing 4 new healthy pods. A total of 20 replicates were performed. The results showed that C. serratus has an average lifespan of 14 days. However, the female (16 days) lived longer and laid an average of 34 eggs during her lifetime. The egg-laying period lasted 14 days, the number of eggs increased until reaching a maximum peak on the 4th day. C. serratus has an embryonic development time of 3 days and an emergence rate of 66.63%. However, the weight of males and females differed significantly (p = 0.0108). We found an intrinsic rate of natural increase of 0.12 and a population doubling time was 5.68 days. These results have enabled us to gain a better understanding of its development cycle and its capacity for regeneration. This allows us to implement control strategies for better stock protection.

关键词： Biodemographic Parameters Stock Caryedon serratus Tamarindus indica

BIERMER’s Disease: About 4 Cases Diagnosed at Regional University Hospital of Ouahigouya (Chur/Ohg) and literature Review

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Open Journal of Gastroenterology 2024年第9期14卷 322-329页

作者： Zanga Damien Ouattara Stève léonce Zoungrana Saïdou Santi Emeline Agathe Carama Fabien Dembele Bafima Désiré Diarra Alain Bougouma Department of Gastroenteroly Ouahigouya Regional University Hospital Ouahigouya Burkina Faso Department of Neurology Bogodogo University Hospital Ouagadougou Burkina Faso Department of Gastroenterology Yalgado Oudraogo University Hospital Center Ouagadougou Burkina Faso

Megaloblastic pernicious anemia is an autoimmune disorder, considered rare in African context. The objective of this study was to report four clinical cases collected at the CHUR/OHG, and to review the literature. The study population consisted of two men and two women. The clinical manifestations were mainly neurological and hematological. The neurological signs were mainly paresthesia. One patient presented memory problems. On the biological level, macrocytic anemia and vitamin B12 deficiency were reported in two cases prior to treatment while the other two without serological assay of vitamin B12 were put on trial treatment. Anti-intrinsic factor antibodies were positive in three patients. The Schilling test was not used. Upper gastrointestinal endoscopy revealed atrophic fundic gastritis in all four patients who received treatment through intramuscular injection of hydroxocobalamin (vitamin B12). The evolution was favorable after one month of treatment in all cases. The literature review is dominated by clinical case reports, the largest cohorts of which are from the Maghreb.

关键词： Anemia Pernicious Megaloblastic Vitamin B12

Numerical Models and Methods of Atmospheric Parameters Originating in the Formation of the Earth’s Climatic Cycle

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Atmospheric and Climate Sciences 2024年第2期14卷 277-286页

作者： Wend Dolean Arsène ilboudo Kassoum Yamba Windé Nongué Daniel Koumbem Issaka Ouédraogo Dé partement Energie Institut de Recherche en Sciences Appliqu&#233es et Technologies (IRSAT) Ouagadougou Burkina Faso Unité de Formation et de Recherche en Sciences Exactes et Appliqu&#233es Universit&#233 Joseph KI-ZERBO Ouagadougou Burkina Faso

Atmospheric models are physical equations based on the ideal gas law. Applied to the atmosphere, this law yields equations for water, vapor (gas), ice, air, humidity, dryness, fire, and heat, thus defining the model of key atmospheric parameters. The distribution of these parameters across the entire planet Earth is the origin of the formation of the climatic cycle, which is a normal climatic variation. To do this, the Earth is divided into eight (8) parts according to the number of key parameters to be defined in a physical representation of the model. Following this distribution, numerical models calculate the constants for the formation of water, vapor, ice, dryness, thermal energy (fire), heat, air, and humidity. These models vary in complexity depending on the indirect trigonometric direction and simplicity in the sum of neighboring models. Note that the constants obtained from the equations yield 275.156˚K (2.006˚C) for water, 273.1596˚K (0.00963˚C) for vapor, 273.1633˚K (0.0133˚C) for ice, 0.00365 in/s for atmospheric dryness, 1.996 in2/s for humidity, 2.993 in2/s for air, 1 J for thermal energy of fire, and 0.9963 J for heat. In summary, this study aims to define the main parameters and natural phenomena contributing to the modification of planetary climate. .

关键词： Atmospheric Parameter 1 Climatic Cycle 2 Numerical Models 3

Distribution of Atmospheric Pollution in Southern Benin

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Open Journal of Air Pollution 2024年第1期13卷 23-55页

作者： Dossou-Gbete Sèdami Codjo Joël Kpadonou Dominique Gbaguidi An Magloire Elegbede Vitalique Saizonou Kpèssou Virtus Mickael Youssao Abdou Karim Alassane Dovonon Firmin léonce Vodounnon Armand Doctoral School of Exact and Applied Sciences University of Abomey-Calavi (UAC) Abomey-Calavi Benin Ecotoxicology and Quality Study Research Unit Applied Chemistry Study and Research Laboratory Department of Chemical Engineering-Processes (GC-P) Polytechnic School of Abomey-Calavi University of Abomey-Calavi Abomey-Calavi Benin Africa Synergy Group Plus Cotonou Benin

This study focuses on air quality in southern Benin in order to show public authorities what the Beninese populations are exposed to for efficient decision-making. Two sampling campaigns were carried out, one in the wet period and the other in the dry season. The measurements were taken using a monitor called an “Air Quality Monitor”. For data processing, the multiple comparison methods of Dun (1961) and the Wilcoxon test were used. To maintain legitimacy, all spatial data were included in the official cartographic repository of Benin: WGS 1984, Transverse Mercator Universe Projection (UTM), Zone 31 North. The Moran statistic was used to measure the levels of spatial autocorrelation of the variables studied and to test the significance. In order to locate the spatial subsets, the local spatial association indices of Anselin local Moran and Getis-Ord, Gi* were used. In terms of results, on the 13 monitoring sites and the 8 parameters chosen to determine air quality, we do not note any significant inter-seasonal difference. Of the eight parameters, only three parameters present spatial autocorrelation leading to predictions of ambient air quality over the entire study area based on the distance separating the points, namely, PM2.5, PM10 and ambient air quality index (AQI). The localities affected by atmospheric pollution in South Benin are located in the south-western part of Benin, headed by Cotonou, which is heavily polluted by CO2, TCOV, PM10 and PM2.5.

关键词： Spatial Distribution Atmospheric Pollutants Southern Benin

Acute Toxicity and Anthelmintic Effects of Gomphrena serrata l. (Amaranthaceae) Extracts on Adult Worms and Eggs of Haemonchus contortus

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Pharmacology & Pharmacy 2024年第5期15卷 207-221页

作者： Hippolyte Ouedraogo Mohamed Bonewendé Belemlilga Aristide Traore Gilchrist Abdoul laurent Boly Félicité Moyenga Gueswindé Geoffroy Ouedraogo Sylvain ilboudo lazare Belemnaba Sylvin Ouedraogo laboratoire de Recherche-Dé veloppement de Phytom&#233dicaments et M&#233dicaments (LR-D/PM) Institut de Recherche en Sciences de la Sant&#233 (IRSS) Centre National de la Recherche Scientifique et Technologique (CNRST) Ouagadougou Burkina Faso laboratoire de Dé veloppement du M&#233dicament (LADME) Centre de Formation deRecherche et d&#8217Expertises en Sciences du M&#233dicament (CEA-CFOREM) &#201cole Doctorale Sciences de la Sant&#233 (ED2S) Universit&#233 Joseph KI-ZERBO Ouagadougou Burkina Faso International Research laboratory-Environnement Sant&#233 Soci&#233t&#233s (IRL 3189 ESS) CNRS/CNRST/UCAD/UGB/USTTB Ouagadougou Burkina Faso

Gomphrena serrata l. (Amaranthaceae) is a medicinal plant widely used traditionally in rural areas to treat many diseases, including gastrointestinal helminthiasis of small ruminants. This work aims to estimate the plant extracts phytochemical potential and study the activities of the aqueous decoction (GS_AD), aqueous macerate (GS_AM), and hydroalcoholic macerate (GS_HEM) of Gomphrena serrata extracts on two developmental stages (eggs and adult worms) of Haemonchus contortus. Phytochemical screening was carried out. The acute toxicity test was performed according to the Organisation for Economic Co-operation and Development (OECD) test guideline 423. The Haemonchus contortus eggs hatching inhibition test was performed left to incubate for 48 hours in the presence of the different plant extracts at increasing concentrations of 0.125;0.25;0.5;0.625;1;2;3 mg/ml. For the motility inhibition test on adult worms, the worms were contacted with the extracts at concentrations of 0.75;1;1.25;1.5;2;3;4 mg/ml and left to incubate for 24 hours. Albendazole and levamisole were used as standard. Phytochemical screening revealed the presence of tannins, saponins, reducing compounds, coumarins and derivatives, anthocyanins, steroids, triterpenes, and flavonoids. An acute toxicity study showed that the oral lD50 value of G. serrata was estimated to be 5000 mg/kg. All extracts showed an effect on both stages of parasite development. The hatching inhibition rate was 100% from 3 mg/ml for all three extracts. The rate of inhibition of motility was 100% from 4 mg/ml for each extract. HEM is more efficient on eggs and Haemonchus contortus adult worms than other extracts with IC50 of 0.457 mg/ml and lC50 of 1.329 mg/ml, respectively. These results suggest that Gomphrena serrata, a plant used by farmers, has anthelmintic properties.

关键词： Gomphrena serrata Haemonchus contortus Anthelmintic In Vitro

On the functions of astrocyte-mediated neuronal slow inward currents

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Neural Regeneration Research 2024年第12期19卷 2602-2612页

作者： Balázs Pál Department of Physiology Faculty of MedicineUniversity of DebrecenDebrecenHungary

Slow inward currents are known as neuronal excitatory currents mediated by glutamate release and activation of neuronal extra synaptic N-met hyl-D-aspartate receptors with the contribution of *** events are significantly slower than the excitatory postsynaptic *** of slow inward currents are determined by seve ral factors including the mechanisms of astrocytic activation and glutamate release,as well as the diffusion pathways from the release site towards the extra synaptic recepto *** are stimulated by neuronal network activity,which in turn excite neurons,forming an astrocyte-neuron feedback *** as a consequence of brain edema,astrocytic swelling can also induce slow inward currents under pathological *** is a growing body of evidence on the roles of slow inward currents on a single neuron or local network *** events often occur in synchro ny on neurons located in the same astrocytic *** synchronization of neuronal excitability,slow inward currents also set synaptic strength via eliciting timing-dependent synaptic *** addition,slow inward currents are also subject to non-synaptic plasticity triggered by long-la sting stimulation of the excitatory *** note,there might be important regionspecific differences in the roles and actions triggering slow inward *** greater networks,the pathophysiological roles of slow inward currents can be better understood than physiological *** inward currents are identified in the pathophysiological background of autism,as slow inward currents drive early hypersynchrony of the neural *** inward currents are significant contributors to paroxysmal depolarizational shifts/interictal *** events are related to epilepsy,but also found in Alzheimer's disease,Parkinson's disease,and stroke,leading to the decline of cognitive *** with features overlapping with slow inward currents(excitatory,N-methyl-Dasp

关键词： astrocyte cortical spreading depolarization gliotransmission glutamate neural synchronization NMDA receptor paroxysmal depolarizational shift slow inward current